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Big Impact (big + impact)
Selected AbstractsRapid screening in cervical cytology , a simple method with a big impactCYTOPATHOLOGY, Issue 3 2004Chris Faraker No abstract is available for this article. [source] Rapid screening in cervical cytology , a simple method with a big impactCYTOPATHOLOGY, Issue 2 2004Paul Cross No abstract is available for this article. [source] Postural stability of Parkinson's disease patients is improved by decreasing rigidityEUROPEAN JOURNAL OF NEUROLOGY, Issue 2 2005A. Bartoli Postural instability has a big impact on the quality of life of patients with Parkinson's disease (PD) as it often leads to an insecure stance and fall. We investigated if postural stability in these patients improves by decreasing rigidity with a dopaminergic agonist. In our study, we tested eight PD patients with no concomitant diseases. Their age was 61 ± 2 years (mean ± SE) and their Hoehn-Yahr score was 3 ± 0.1. The patients were evaluated according to the Unified Parkinson's Disease Rating Scale for motor function (mUPDRS) and with stabilometric measurements of forward,backward and side-to-side body oscillations during free stance with eyes open. Both evaluations were performed in an ,off' state and in an apomorphine-induced ,on' state. As expected, the mUPDRS score was significantly decreased in the ,on' state with posture being improved in six patients, gait in eight patients and postural stability in seven of eight patients. In addition, apomorphine caused a significant reduction of the relative amplitude of lower frequencies and an increase of the relative amplitude of higher frequencies of forward,backward body oscillations. The results of stabilometry and mUPDRS evaluations are in agreement with the effect of apomorphine on rigidity, indicating that postural stability of PD patients is improved by decreasing rigidity. [source] The Effect of Exercise Date Uncertainty on Employee Stock Option ValueJOURNAL OF BUSINESS FINANCE & ACCOUNTING, Issue 5-6 2003Brian A. Maris The IASC recently recommended that employee compensation in the form of stock options be measured at the ,fair value' based on an option pricing model and the value should be recognized in financial statements. This follows adoption of SFAS No. 123 in the United States, which requires firms to estimate the value of employee stock options using either a Black-Scholes or binomial model. Most US firms used the B-S model for their 1996 financial statements. This study assumes that option life follows a Gamma distribution, allowing the variance of option life to be separate from its expected life. The results indicate the adjusted Black-Scholes model could overvalue employee stock options on the grant date by as much as 72 percent for nondividend paying firms and by as much as 84 percent for dividend paying firms. The results further demonstrate the sensitivity of ESO values to the volatility of the expected option life, a parameter that the B-S model or a Poisson process cannot accommodate. The variability of option life has an especially big impact on ESO value for firms whose ESOs have a relatively short life (5 years, for example) and high employee turnover. For such firms, the results indicate a binomial option pricing model is more appropriate for estimating ESO value than the B-S type model. [source] Micro research with big impactCANCER, Issue 3 2010Carrie Printz No abstract is available for this article. [source] A supply chain design model with unreliable supplyNAVAL RESEARCH LOGISTICS: AN INTERNATIONAL JOURNAL, Issue 8 2007Lian Qi Abstract Uncertainties abound within a supply chain and have big impacts on its performance. We propose an integrated model for a three-tiered supply chain network with one supplier, one or more facilities and retailers. This model takes into consideration the unreliable aspects of a supply chain. The properties of the optimal solution to the model are analyzed to reveal the impacts of supply uncertainty on supply chain design decisions. We also propose a general solution algorithm for this model. Computational experience is presented and discussed. © 2007 Wiley Periodicals, Inc. Naval Research Logistics, 2007 [source] | ||||||||||