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Water Control (water + control)
Selected AbstractsWATER CONTROL AND CEREAL MANAGEMENT ON THE BRONZE AGE IBERIAN PENINSULA: LA MOTILLA DEL AZUEROXFORD JOURNAL OF ARCHAEOLOGY, Issue 3 2008GONZALO ARANDA Summary. Archaeological research conducted in the La Mancha region (central area of the Iberian Peninsula) has made it possible to identify motillas. This specific type of archaeological site consists of a central fortification surrounded by an inhabited area. They appear in high densities throughout the plains of this area, distributed at regular intervals and located in places where the phreatic level is closest to the surface and the water has low salinity. The strong relationship between sites and water has subsequently been supported by fieldwork, especially in the Motilla del Azuer settlement, where a complex well that was cut into the natural terrace to reach the phreatic level has been documented. Research has also demonstrated that the large-scale storage of cereals was another significant function. The quantity and capacity of the different storage systems documented in two large enclosures suggest that these sites were engaged in the control and management of cereals. [source] Bakery Food Manufacture and Quality: Water Control and EffectsINTERNATIONAL JOURNAL OF FOOD SCIENCE & TECHNOLOGY, Issue 11 2009C. E. (Chuck) Walker No abstract is available for this article. [source] The Collapse of the Classic Maya: A Case for the Role of Water ControlAMERICAN ANTHROPOLOGIST, Issue 3 2002Lisa J. Lucero This article focuses on the role of water control in the emergence and demise of Classic Maya political power (c. C.E. 250-950), one that scholars have long underestimated. The scale of water control correlates with the degree of political power, reflected in three levels of Maya civic-ceremonial centers,regional, secondary, and minor. Such power derives from a complex relationship among center location, seasonal water supply, amount of agricultural land, and settlement density. Maya kings monopolized artificial reservoirs and other water sources during annual drought, providing the means to exact tribute from subjects. Climate change undermined the institution of rulership when existing ceremonies and technology failed to provide sufficient water. The collapse of rulers' power at regional centers in the Terminal Classic (c. C.E. 850-950) had differing impacts on smaller centers. Secondary and minor centers not heavily dependent on water control survived the drought and the collapse of regional centers. [Keywords: political power, water control, Classic Maya collapse] [source] Resistance of apple trees to Cydia pomonella egg-laying due to leaf surface metabolitesENTOMOLOGIA EXPERIMENTALIS ET APPLICATA, Issue 1 2008Nadia Lombarkia Abstract During host plant selection and particularly after alighting on a plant, chemical cues from the plant surface influence an insect's acceptance of the plant and, subsequently, its egg-laying behaviour. Primary metabolites in the phylloplane may be more important than hitherto known. We have shown that soluble carbohydrates, such as glucose, fructose, and sucrose, and sugar alcohols, such as sorbitol, quebrachitol, and myo -inositol, can be detected by insects after contacting the plant and that they positively influence egg-laying of the codling moth, Cydia pomonella (L.) (Lepidoptera: Tortricidae), on apple trees. We addressed the question whether a lack of these substances could also explain apple tree resistance to C. pomonella in terms of reduced egg-laying. Leaf surface washings were collected in an apple orchard by spraying water on the resistant cultivar X65-11 and on the susceptible cultivar P5R50A4. The washings were tested on a nylon cloth on isolated females under no-choice conditions. The washings were analysed and synthetic blends, each consisting of the six metabolites in the proportions established in the leaf surface washings of both cultivars, were then tested for their effect on egg-laying of C. pomonella. Dose,response egg-laying tests were carried out on substrates impregnated with the X65-11 leaf surface blend at 1, 100, 1 000, and 10 000 times the natural dose. Egg-laying behaviour in the bioassays with leaf surface washings of both cultivars closely resembled egg-laying in the orchard. Washings of P5R50A4 stimulated egg-laying to a greater extent than those of X65-11 and the water control. Synthetic blends reduced substrate acceptance and egg-laying, compared to the washings of X65-11. Ratios between components within the blend are responsible for this resistance. In conclusion, quantities and ratios of the six primary metabolites found on the leaf surface may influence host preference of C. pomonella as well as their egg-laying behaviour, thus they may play a role in the trees' resistance to the codling moth. [source] First Documentation of Cultural Transmission of Predator Recognition by Larval AmphibiansETHOLOGY, Issue 6 2007Maud C. O. Ferrari Predation is a pervasive selective agent shaping a prey's behaviour, morphology and life history. To survive, prey animals have to respond adaptively to predation threats and this can be achieved through learned predator recognition. Cultural transmission of predator recognition is likely a widespread means of learning in social animals, including mammals, birds and fishes. However, no studies have investigated the cultural transmission of predator recognition in amphibians. In our study, we examined whether naïve woodfrog (Rana sylvatica) tadpoles can acquire the recognition of the odour of a predatory tiger salamander (Ambystoma tigrinum) from experienced conspecifics. After conditioning some tutors to recognize salamander odour, we paired naïve observer tadpoles with either a salamander-naïve or salamander-experienced tutor and exposed the pairs to either salamander odour or a water control. Observers were subsequently tested alone for a response to salamander odour. We found that when given salamander odour, observer tadpoles that were paired with a salamander-experienced tutor successfully learned to recognize the salamander odour as a threat, whereas the observers paired with salamander-naïve tutors did not. Likewise, tadpoles exposed to the water control did not learn to recognize the salamander regardless of whether they were paired with a naïve or experienced tutor. This is the first study demonstrating cultural transmission of predator recognition in an amphibian species. [source] A multi-sample design for assessing the comedolytic activity of topical productsINTERNATIONAL JOURNAL OF COSMETIC SCIENCE, Issue 5 2004H. Knaggs Synopsis Background:, Facial comedolytic studies allow testing of a maximum of two products. The upper back provides a larger area with a more uniform distribution of microcomedones for comedolytic studies. Objective:, To design a multi-sample method for assessing comedolytic activity of topical products on the back. The effect of season on product discrimination was also explored. Methods:, Three cleansing formulations (products B, C and D), a negative water control and 0.025% Retin-A® cream (positive control) were tested. Seven subjects were recruited in summer and nine in fall. Products were applied for 8 weeks, comedolysis was assessed by visually evaluating cyanoacrylate follicular biopsies taken at baseline and post-treatment. Results:, In all data sets (summer, fall and combined), sites treated with Retin-A® had a significantly lower number of microcomedones as compared to the negative water control. In addition, cleansers B and D showed a significant reduction from baseline in the fall and combined (summer and fall) data, but not in summer data alone indicating different responses to treatment during the year. Conclusions:, The design was sensitive enough to detect differences between cleansing formulations under normal washing conditions. Reduced sensitivity observed during summer suggests hot humid conditions may decrease the comedolytic performance of topical products. Résumé Arrière-plan:, Les études d'agents comédolytiques sur le visage permettent de tester un maximum de deux produits. La partie supérieure du dos offre une plus grande surface couverte d'une distribution plus uniforme de micro-comédons. Objectif:, Mettre au point une méthode multi échantillons permettant d'appréhender l'activité comédolytique de produits appliqués de façon topique sur le dos. L'influence de la saison sur la différenciation des produits a également étéétudiée. Méthode:, Trois formulations lavantes (B, C, D), l'eau en tant que témoin négatif, une crème contenant 0,025% de rétina-A® en tant que témoin positif ont été testées. Sept sujets ont été recrutés en été, neuf l'ont été en automne. Les produits ont été appliqués durant 8 semaines. La comédolyse a étéévaluée par observation visuelle de biopsies folliculaires au cyanoacrylate faite avant et après traitement. Résultat:, Dans chaque groupe de résultats (été, automne et cumulé), les zones traitées avec la rétina-A® possèdent un nombre de micro-comédons statistiquement plus faible, comparé au témoin négatif (l'eau). De plus, les produits de nettoyage B et D ont montré une diminution significative par rapport à la situation avant traitement en automne, ainsi qu'en situation cumulé (automne + été), mais pas en été. Ces résultats indiquent des réponses différentes au traitement durant l'année. Conclusion:, La méthode est assez sensible pour détecter la différence entre des formulations nettoyantes utilisées sous condition normale d'utilisation. La diminution de sensibilité observée en été laisse suggérer que des conditions climatiques chaudes et humides diminuent l'efficacité comédolytique des produits appliqués de façon topique. [source] Irrigation and drainage systems research and development in the 21st century,IRRIGATION AND DRAINAGE, Issue 4 2002Bart Schultz irrigation; drainage; développement durable; système de réseau Abstract One critical problem confronting mankind today is how to manage the intensifying competition for water between expanding urban centres, traditional agricultural activities and in-stream water uses dictated by environmental concerns. In the agricultural sector, the dwindling number of economically attractive sites for large-scale irrigation and drainage projects limits the prospects of increasing the gross cultivated area. Therefore, the required increase in agricultural production will necessarily rely largely on a more accurate estimation of crop water requirements on the one hand, and on major improvements in the construction, operation, management and performance of existing irrigation and drainage systems, on the other. The failings of present systems and the inability to sustainably exploit surface and groundwater resources can be attributed essentially to poor planning, design, system management and development. This is partly due to the inability of engineers, planners and managers to adequately quantify the effects of irrigation and drainage projects on water resources and to use these effects as guidelines for improving technology, design and management. To take full advantage of investments in agriculture, a major effort is required to modernize irrigation and drainage systems and to further develop appropriate management strategies compatible with the financial and socio-economic trends, and the environment. This calls for a holistic approach to irrigation and drainage management and monitoring so as to increase food production, conserve water, prevent soil salinization and waterlogging, and to protect the environment. All this requires, among others, enhanced research and a variety of tools such as water control and regulation equipment, remote sensing, geographic information systems, decision support systems and models, as well as field survey and evaluation techniques. To tackle this challenge, we need to focus on the following issues: affordability with respect to the application of new technologies; procedures for integrated planning and management of irrigation and drainage systems; analysis to identify causes and effects constraining irrigation and drainage system performance; evapotranspiration and related calculation methods; estimation of crop water requirements; technologies for the design, construction and modernization of irrigation and drainage systems; strategies to improve irrigation and drainage system efficiency; environmental impacts of irrigation and drainage and measures for creating and maintaining sustainability; institutional strengthening, proper financial assessment, capacity building, training and education. Copyright © 2002 John Wiley & Sons, Ltd. Résumé Aujourd'hui le problème critique pour l'humanité est comment manier la compétition intensifiante pour de l'eau entre les centres urbains en expansion, pour des activités traditionnellement agricoles et pour l'usage de l'eau fluviale prescrit par des conditions écologistes. Dans le secteur agricole les perspectives d'agrandir les champs cultivés bruts sont limitées par le nombre diminuant des terrains économiquement attractifs pour des projets d'irrigation et du drainage de grande envergure. Par conséquent l'augmentation nécessaire de la production agricole comptera surtout sur une évaluation plus précise du besoin des plantes d'un côté, et de l'autre sur de grandes améliorations dans la construction, dans l'opération, dans le management et dans la performance des systèmes d'irrigation et du drainage. On peut attribuer les défauts des systèmes actuels et l'incompétence d'exploiter durablement les ressources hydriques de surface et souterraines au planification, au système de la gestion de l'eau et au système du développement. Cela est partiellement dû à l'incapacité des ingénieurs, des planificateurs et des gérants, de quantifier adéquatement les effets des projets d'irrigation et de drainage sur les ressources hydriques et d'utiliser ces résultats pour améliorer la technologie, la planification et la gestion de l'eau. Pour profiter le mieux possible des investissements dans l'agriculture, on exige un effort considérable pour moderniser les systèmes d'irrigation et de drainage et pour développer des stratégies de gestion de l'eau qui doivent être appropriées et compatibles avec les tendances financières et socio-économiques et avec l'environnement. Ceci a besoin d'une procédure holistique pour la gestion et le monitorage de l'eau, pour augmenter la production d'aliments, pour conserver l'eau, pour prévenir la salination du sol et pour protéger l'environnement. Tout cela demande, entre autres choses, une recherche d'avant-garde et une variété d'instruments comme les contrôles du régime hydrique et les appareils de régulation, la télédétection, les systèmes de l'information géographique, les systèmes et les modèles de support de décision et de même les levés sur le terrain et les techniques d'évaluation. Pour entreprendre ce défi nous devons nous concentrer sur les questions suivantes: capacité de mettre enoeuvre des technologies nouvelles; le développement des procédures pour intégrer la planification et la gestion des systèmes d'irrigation et de drainage; l'analyse pour identifier les causes et les effets de forcer à la performance des systèmes d'irrigation et de drainage; l'évapotranspiration et les méthodes de calcul en question; l'évaluation des exigences hydriques des cultures; les technologies pour le dessein, la construction et la modernisation des projets d'irrigation et de drainage; les stratégies pour améliorer l'efficacité des systèmes d'irrigation et de drainage; les impacts des projets d'irrigation et de drainage et des mesures appropriées pour créer et entretenir la durabilité; l'amélioration du contexte institutionnel, l'évaluation financière, la formation et l'amélioration des compétences techniques. Copyright © 2002 John Wiley & Sons, Ltd. [source] Susceptibility of immature stages of Chrysoperla rufilabris (Neurop., Chrysopidae) to pyriproxyfen, a juvenile hormone analogJOURNAL OF APPLIED ENTOMOLOGY, Issue 2-3 2002T.-Y. Chen Effects of pyriproxyfen (Knack), a juvenile analog, at three concentrations (10, 50 and100 mg [AI]/l), on survival and development of all immature stages of Chrysoperla rufilabris (Burmeister), were determined in the laboratory. Pyriproxyfen significantly reduced the survival rates when eggs, first and third instars were treated, but not when the second instars and pupae were treated. When eggs were treated, the two higher concentrations reduced the eggs viability by 33.3,50%, and only 0.0,6.7% developed to adults. The lowest concentration of pyriproxyfen (10 mg [AI]/l) caused high mortality on third instars, not on other stages, indicating the third instar was the most vulnerable stage. Pyriproxyfen had significant effects on development for all immature C. rufilabris that successfully developed to adults with variations among the developmental stages and concentrations. The overall developmental duration from eggs to adults when eggs, first, and third instars were treated were 2.6,4.2, 2.4,4.1 respectively, and 6.0,7.1 d longer than those in water control, respectively. However, the overall developmental durations from eggs to adults were 0.5,1.2 d shorter than in water control when the second instars were treated with pyriproxyfen. The compatibility of pyriproxyfen with natural enemies in integrated pest management programs is discussed. [source] Efficacy of Listerine® Antiseptic in reducing viral contamination of salivaJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 4 2005Timothy F. Meiller Abstract Aim: The anti-viral efficacy of oral antimicrobial rinses has not been adequately studied in terms of potential clinical significance. As a follow-up to an in vitro study on the effect of oral antiseptics on Herpes simplex virus, Type 1, this study was undertaken to evaluate the in vivo effect of an essential oil containing oral antiseptic on the reduction of viral titer in saliva during active viral infection. Method: Patients were recruited and evaluated in a single visit protocol at the onset of a perioral outbreak, consistent historically and clinically with recurrent Herpes labialis. Direct immunofluorescence of cytological smears of the lesions/oral fluids was used to confirm Herpes simplex virus types I or II. Patients were randomly assigned to one of two treatment groups: (1) active ingredient and (2) sterile water control. The viral lesion was evaluated as to clinical stage according to standard protocol. Salivary fluid samples were taken: (1) at baseline; (2) immediately following a 30 s rinse; (3) 30 min. after the 30 s rinse; and (4) on the repeat trial, also at 60 min. after the 30 s rinse. All samples were evaluated for viral titer and results compared. Results: In Trial 1, the sample population consisted of 19 males and 21 females with an average age of 29.2 and in Trial 2, 21 males, 19 females with an average age of 28. In both Trials 1 and 2, recoverable infectious virions were reduced to zero after a 30 s experimental rinse; whereas, the control rinse resulted in a non-significant (p>0.05) reduction. The experimental group also demonstrated a continued significant (p<0.05) reduction 30 min. post rinse when compared with baseline while the control group returned to baseline levels. In Trial 2, the 60 min. post rinse follow-up demonstrated a 1,2 log residual reduction from baseline in the experimental group; however, this was not significant. Conclusions: There is clinical efficacy in utilizing an oral rinse with the antimicrobial agent Listerine® Antiseptic in reducing the presence of viral contamination in oral fluids for at least 30 min. after oral rinse. The risk of viral cross contamination generated from these oral fluids in person to person contact or during dental treatment may be reduced. [source] Effect of an essential oilcontaining antiseptic mouthrinse on plaque and salivary Streptococcus mutans levelsJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 3 2000D. H. Fine Abstract Background: Clinical studies in which antimicrobial mouthrinses were shown to have significant antiplaque activity most frequently have used gingivitis as the clinically relevant endpoint. However, there is evidence to suggest that mouthrinses containing active agents effective against Streptococcus mutans, such as chlorhexidine, may also have a rôle in inhibiting dental caries. This clinical study was conducted to determine the effect of 2×-daily rinsing with an essential oilcontaining antiseptic mouthrinse (Listerine® Antiseptic) on levels of recoverable S. mutans and total streptococci in supragingival interproximal plaque and in saliva. Additionally, a follow-up in vitro study is reported which determined whether a differential susceptibility to the antiseptic mouthrinse exists among different strains of streptococci. Method: Following baseline saliva and plaque sampling for quantification of recoverable S. mutans and total streptococci, 29 qualifying subjects were randomly assigned either the essential oil mouthrinse or a sterile water control. They rinsed with 20 ml for 30 s 2×daily for 11 days and once on the 12th day, in addition to their usual oral hygiene procedures. On day 12, saliva and plaque samples were again collected and microbiological quantification performed. The procedures were repeated with the alternate rinse after a 1-week washout period. Results: The essential oil mouthrinse produced respective reductions of 69.9% and 75.4% in total recoverable streptococci and in S. mutans in plaque, and corresponding reductions of 50.8% and 39.2% in saliva. The in vitro study revealed that streptococci from the mutans group were more susceptible to the bactericidal activity of the essential oil mouthrinse than streptococci from the mitis group. Conclusions: As antimicrobial mouthrinses are most frequently recommended to patients whose mechanical oral hygiene procedures are not adequate for the control of supragingival plaque and gingivitis, this study provides an additional rationale for the inclusion of the essential-oil mouthrinse as an adjunct to daily oral hygiene procedures. [source] Landing responses of Anopheles gambiae elicited by oxocarboxylic acidsMEDICAL AND VETERINARY ENTOMOLOGY, Issue 2 2002T. P. Healy Abstract A wind tunnel bioassay and video system were used to observe Anopheles gambiae Giles sensu stricto (Diptera: Culicidae) landing on glass cylinders, heated to human skin temperature (34°C) and treated with aqueous solutions of oxocarboxylic acids. Six of nine compounds tested: 2-oxobutanoic, 2-oxo-3-methylbutanoic, 2-oxopentanoic, 2-oxo-3-methylpentanoic, 2-oxo-4-methylpentanoic and 2-oxohexanoic elicited significant landing responses in comparison to a water control. Landing responses appeared to be restricted to C4,C6, 2-oxocarboxylic acids. A solution of 1 µg/µL of 2-oxopentanoic acid elicited the highest level of response that was temperature dependent: significant numbers of landings occurred only within ±,2°C of human skin temperature. Chemical analysis by linked gas-liquid chromatography/mass spectrometry of methyl-oxime, trimethylsilyl derivatized samples of human sweat extracts revealed the presence of 2-oxopropanoic (pyruvic) acid and three behaviourally active, branched chain acids: 2-oxo-3-methylbutanoic, 2-oxo-3-methylpentanoic and 2-oxo-4-methylpentanoic. [source] Manipulation of glycemic response with isomaltulose in a milk-based drink does not affect cognitive performance in healthy adultsMOLECULAR NUTRITION & FOOD RESEARCH (FORMERLY NAHRUNG/FOOD), Issue 4 2010Louise Dye Abstract Previous research suggests that glucoregulation and nutrient interventions, which alter circulating glucose, impact cognitive function. To examine the effect of modulating glycemic response using isomaltulose on cognitive function 24 healthy male adult participants consumed energy and macronutrient-matched milk-based drinks containing 50,g isomaltulose, 50,g sucrose or a water control in a counterbalanced within-subject design. Interstitial glucose was measured continuously in 12 subjects and all provided 9 capillary measures on each test day. A 30-min cognitive test battery was administered before and twice (+35 and +115,min) after drink ingestion. Immediate, delayed, recognition, verbal and working memory, and psychomotor performance were assessed. Glycemic profiles induced by the drinks differed significantly during the first but not the second post-drink test battery. Neither administration of the sucrose nor isomaltulose drinks produced consistent effects on verbal or working memory, or psychomotor performance. This study used isomaltulose as an investigative tool to lower glycemic response. Importantly, it demonstrates a lack of effect of modulating glucose on cognitive performance based on reliable, continuously measured glycemia. It refutes the hypothesis that glycemia is associated with cognitive performance and questions the suggestion that isomaltulose has an effect on cognitive performance. [source] The Collapse of the Classic Maya: A Case for the Role of Water ControlAMERICAN ANTHROPOLOGIST, Issue 3 2002Lisa J. Lucero This article focuses on the role of water control in the emergence and demise of Classic Maya political power (c. C.E. 250-950), one that scholars have long underestimated. The scale of water control correlates with the degree of political power, reflected in three levels of Maya civic-ceremonial centers,regional, secondary, and minor. Such power derives from a complex relationship among center location, seasonal water supply, amount of agricultural land, and settlement density. Maya kings monopolized artificial reservoirs and other water sources during annual drought, providing the means to exact tribute from subjects. Climate change undermined the institution of rulership when existing ceremonies and technology failed to provide sufficient water. The collapse of rulers' power at regional centers in the Terminal Classic (c. C.E. 850-950) had differing impacts on smaller centers. Secondary and minor centers not heavily dependent on water control survived the drought and the collapse of regional centers. [Keywords: political power, water control, Classic Maya collapse] [source] Abscisic acid is involved in the response of grape (Vitis vinifera L.) cv. Malbec leaf tissues to ultraviolet-B radiation by enhancing ultraviolet-absorbing compounds, antioxidant enzymes and membrane sterolsPLANT CELL & ENVIRONMENT, Issue 1 2010FEDERICO J. BERLI ABSTRACT We investigated the interactions of abscisic acid (ABA) in the responses of grape leaf tissues to contrasting ultraviolet (UV)-B treatments. One-year-old field-grown plants of Vitis vinifera L. were exposed to photosynthetically active radiation (PAR) where solar UV-B was eliminated by using polyester filters, or where PAR was supplemented with UV-B irradiation. Treatments combinations included weekly foliar sprays of ABA or a water control. The levels of UV-B absorbing flavonols, quercetin and kaempferol were significantly decreased by filtering out UV-B, while applied ABA increased their content. Concentration of two hydroxycinnamic acids, caffeic and ferulic acids, were also increased by ABA, but not affected by plus UV-B (+UV-B) treatments. Levels of carotenoids and activities of the antioxidant enzymes, catalase, ascorbate peroxidase and peroxidase were elevated by +ABA treatments, but only if +UV-B was given. Cell membrane , -sitosterol was enhanced by ABA independently of +UV-B. Changes in photoprotective compounds, antioxidant enzymatic activities and sterols were correlated with lessened membrane harm by UV-B, as assessed by ion leakage. Oxidative damage expressed as malondialdehyde content was increased under +UV-B treatments. Our results suggest that the defence system of grape leaf tissues against UV-B is activated by UV-B irradiation with ABA acting downstream in the signalling pathway. [source] Induced systemic resistance against three foliar diseases of Agrostis stolonifera by (2R,3R)-butanediol or an isoparaffin mixtureANNALS OF APPLIED BIOLOGY, Issue 2 2010A.M. Cortes-Barco Induced systemic resistance (ISR) is a type of plant defence mechanism typically activated by non-pathogenic root-associated micro-organisms and systemic priming of gene expression in response to subsequent pathogen challenge. ISR was found to be activated by PC1, a mixture of food-grade synthetic isoparaffins and (2R,3R)-butanediol, a volatile organic compound produced by bacteria. In controlled environment tests, application of PC1 or (2R,3R)-butanediol to the soil reduced the diseased leaf area of Agrostis stolonifera by 20,40% for the fungal pathogens, Microdochium nivale, Rhizoctonia solani or Sclerotinia homoeocarpa compared to the water control. In A. stolonifera, expression of the jasmonate synthesis-related genes, AsAOS1, encoding an allene oxide synthase, and AsOPR4, encoding a 12-oxo-phytodienoic acid reductase, and expression of a pathogenesis-related protein gene, AsGns5, encoding an acidic , -1,3-glucanase, were primed for increased expression by PC1 or (2R,3R)-butanediol when M. nivale was inoculated 7 days later. However, the compounds differed in their ability to induce expression prior to pathogen challenge. PC1 induced AsAOS1 expression upon treatment, whereas (2R,3R)-butanediol induced expression of AsOPR4 and AsGns5 upon treatment. These results indicate that both (2R,3R)-butanediol and PC1 can produce ISR in A. stolonifera but may do so through different mechanisms. [source] The Interaction of Gestational and Postnatal Ethanol Experience on the Adolescent and Adult Odor-Mediated Responses to Ethanol in Observer and Demonstrator RatsALCOHOLISM, Issue 10 2010Amber M. Eade Background:, Gestational ethanol exposure enhances the adolescent reflexive sniffing response to ethanol odor. Postnatal exposures of naïve animals as either an observer (i.e., conspecific) or demonstrator (i.e., intoxicated peer) using a social transmission of food odor preference paradigm also yields enhanced odor-mediated responses. Studies on the interaction of fetal and postnatal exposures using the social transmission paradigm have been limited to the responses of observers. When combined, the enhanced response is greater than either form of exposure alone and, in observer females, yields adult persistence. The absence of a male effect is noteworthy, given that chemosensory mechanisms are suggested to be an important antecedent factor in the progression of ethanol preference. Observers gain odor information on the breath of the demonstrator through social interaction. Demonstrators experience the pharmacologic properties of ethanol along with retronasal and hematogenic olfaction. Thus, we tested whether augmentation of the fetal ethanol-induced behavioral response with postnatal exposure as a demonstrator differed from that as an observer. We also examined whether re-exposure as a demonstrator yields persistence in both sexes. Methods:, Pregnant dams were fed an ethanol containing or control liquid diet throughout gestation. Progeny received four ethanol or water exposures: one every 48 hours through either intragastric infusion or social interaction with the infused peer beginning on P29. The reflexive behavioral sniffing response to ethanol odor was tested at postnatal (P) day 37 or P90, using whole-body plethysmography. Results:, When tested in either adolescence or adulthood - fetal ethanol exposed adolescent ethanol observers and demonstrators significantly differed in their odor-mediated response to ethanol odor both between themselves and from their respective water controls. Nonetheless, adolescent ethanol re-exposure as a demonstrator, like an observer, enhanced the reflexive sniffing response to ethanol odor at both testing ages by augmenting the known effects of prior fetal ethanol experience. At each age, the magnitude of the enhanced odor response in demonstrators was similar to that of observers. Interestingly, only re-exposure as a demonstrator resulted in persistence of the behavioral response into adulthood in both sexes. Conclusions:, The method of ethanol re-exposure plays an important role in prolonging the odor-mediated effects of fetal exposure. While ethanol odor-specific exposure through social interaction is important, additional factors such as the pairing of retronasal and hematogenic olfaction with ethanol's intoxicating properties appear necessary to achieve persistence in both sexes. [source] Oseltamivir Treatment Prevents the Increased Influenza Virus Disease Severity and Lethality Occurring in Chronic Ethanol Consuming MiceALCOHOLISM, Issue 8 2010Ryan A. Langlois Background:, Chronic consumption of ethanol (EtOH) is well recognized to lead to defective innate and adaptive immune responses and increase the severity of pulmonary infections. Our own studies have demonstrated that chronic EtOH consumption decreases CD8 T-cell immunity to influenza virus infections (IAV) leading to severe infections and mortality. Interestingly, antiviral treatment of IAVs has been shown to be compromised in mice and humans that are immuno-deficient. It is known that EtOH can alter the pharmacokinetics of antivirals. Therefore, the effectiveness of influenza antiviral therapy during chronic ethanol consumption remains in question. Methods:, BALB/c mice were placed on 18% (w/v) EtOH in their drinking water for 8 weeks. Chronic EtOH consuming and water controls were then treated with 10 mg/kg oseltamivir orally and infected intranasally with influenza virus 4 hours post-oseltamivir treatment. The mice were then treated with oseltamivir twice daily until day 7 postinfection. Influenza disease severity was measured by morbidity and mortality, pulmonary viral titers, and histology. Results:, Chronic EtOH consuming mice infected with IAV and treated with oseltamivir have decreased morbidity and mortality, pulmonary viral titers, and pulmonary pathology compared to untreated EtOH mice. Conclusions:, Despite the severe immune defect seen in chronic EtOH mice as well as the potential for EtOH to inhibit the conversion of oseltamivir into an active form, treatment with oseltamivir reduces viral shedding as well as disease severity. These data suggest that the combination of a limited adaptive immune response plus the anti-IAV drug oseltamivir is sufficient to curb high mortality and mediate resolution of IAVs in mice chronically consuming ethanol. [source] Dose,response effects of clove oil from Syzygium aromaticum on the root-knot nematode Meloidogyne incognita,PEST MANAGEMENT SCIENCE (FORMERLY: PESTICIDE SCIENCE), Issue 3 2008Susan LF Meyer Abstract BACKGROUND: Clove oil, derived from the plant Syzygium aromaticum(L.) Merr. & Perry, is active against various organisms, and was prepared in a soy lecithin/detergent formulation to determine concentrations active against the root-knot nematode Meloidogyne incognita (Kofoid and White) Chitwood. RESULTS: In microwell assays, the mean effective clove oil concentration that reduced egg hatch by 50% (EC50) was 0.097% (v/v) clove oil; the EC50 for second-stage juvenile (J2) viability was 0.145% clove oil (compared with carrier control treatments). Volatiles from 5.0% clove oil reduced nematode egg hatch in water by 30%, and decreased viability of hatched J2 by as much as 100%. Reductions were not as large with nematodes in carrier. In soil trials with J2 recovered from Baermann funnels, the EC50 = 0.192% clove oil (compared with water controls). CONCLUSION: The results demonstrated that the tested formulation is active against M. incognita eggs and J2, that the EC50 values for J2 in the microwell studies and the soil recovery tests were similar to each other and that direct contact with the clove oil is needed for optimal management results with this natural product. Published in 2007 by John Wiley & Sons, Ltd. [source] | |||||||||||||||||||||||||||||||