Wallis Test (Walli + test)

Distribution by Scientific Domains
Distribution within Medical Sciences

Kinds of Wallis Test

  • kruskal Walli test


  • Selected Abstracts


    Genetic study of the myelin oligodendrocyte glycoprotein (MOG) gene in schizophrenia

    GENES, BRAIN AND BEHAVIOR, Issue 1 2005
    G. Zai
    Schizophrenia (SCZ) is a neuropsychiatric disorder that affects approximately 1% of the general population. The human leukocyte antigen (HLA) system has been implicated in several genetic studies of SCZ. The myelin oligodendrocyte glycoprotein (MOG) gene, which is located close to the HLA region, is considered a candidate for SCZ due to its association with white matter abnormalities and its importance in mediating the complement cascade. Four polymorphisms in the MOG gene (CA)n (TAAA)n, and two intronic polymorphisms, C1334T and C10991T, were investigated for the possibility of association with SCZ using 111 SCZ proband and their families. We examined the transmission of the alleles of each of these polymorphisms with the transmission disequilibrium test. We did not observe significant evidence for biased transmission of alleles at the (CA)n (,2 = 2.430, 6 df, P = 0.876) (TAAA)n (,2 = 3.550, 5 df, P = 0.616), C1334T (,2 = 0.040, 1 df, P = 0.841) and C10991T (,2 = 0.154, 1 df, P = 0.695) polymorphisms. Overall haplotype analysis using the TRANSMIT program was also not significant (,2 = 7.954, 9 df, P = 0.539). Furthermore, our results comparing mean age at onset in the genotype groups using the Kruskal,Wallis Test were not significant. Our case-control analyses (182 cases age-, sex- and ethnicity-matched with healthy controls) and combined z -score [(CA)n: z -score =,1.126, P = 0.130; (TAAA)n: z -score = ,0.233, P = 0.408; C1334T: z -score = 0.703, P = 0.241; C10991T: z -score = 0.551, P = 0.291] were also not significant. Although our data are negative, the intriguing hypothesis for MOG in SCZ may warrant further investigation of this gene. [source]


    Emergency Department Treatment of Viral Gastritis Using Intravenous Ondansetron or Dexamethasone in Children

    ACADEMIC EMERGENCY MEDICINE, Issue 10 2006
    Christine M. Stork PharmD
    Abstract Objectives To compare the efficacy of intravenous ondansetron or dexamethasone compared with intravenous fluid therapy alone in children presenting to the emergency department with refractory vomiting from viral gastritis who had failed attempts at oral hydration. Methods This double-blind, randomized, controlled trial was performed in a tertiary care pediatric emergency department. Children aged 6 months to 12 years presenting with more than three episodes of vomiting in the past 24 hours, mild/moderate dehydration, and failed oral hydration were included. Patients with other medical causes were excluded. Subjects were randomized to dexamethasone 1 mg/kg (15 mg maximum), ondansetron 0.15 mg/kg, or placebo (normal saline [NS], 10 mL). All subjects also received intravenous NS at 10,20 mL/kg/hr. Oral fluid tolerance was evaluated at two and four hours. Those not tolerating oral fluids at four hours were admitted. Discharged patients were evaluated at 24 and 72 hours for vomiting and repeat health care visits. The primary study outcome was hospitalization rates between the groups. Data were analyzed using chi-square test, Kruskal,Wallis test, Mantel,Haenszel test, and analysis of variance, with p < 0.05 considered significant. Results A total of 166 subjects were enrolled; data for analysis were available for 44 NS-treated patients, 46 ondansetron-treated patients, and 47 dexamethasone-treated patients. Hospital admission occurred in nine patients (20.5%) receiving placebo (NS alone), two patients (4.4%) receiving ondansetron, and seven patients (14.9%) receiving dexamethasone, with ondansetron significantly different from placebo (p = 0.02). Similarly, at two hours, more ondansetron-treated patients (39 [86.6%]) tolerated oral hydration than NS-treated patients (29 [67.4%]; relative risk, 1.28; 95% confidence interval = 1.02 to 1.68). There were no differences in number of mean episodes of vomiting or repeat visits to health care at 24 and 72 hours in the ondansetron, dexamethasone, or NS groups. Conclusions In children with dehydration secondary to vomiting from acute viral gastritis, ondansetron with intravenous rehydration improves tolerance of oral fluids after two hours and reduces the hospital admission rate when compared with intravenous rehydration with or without dexamethasone. [source]


    Analysis of the gutta-percha filled area in C-shaped mandibular molars obturated with a modified MicroSeal technique

    INTERNATIONAL ENDODONTIC JOURNAL, Issue 3 2009
    R. Ordinola-Zapata
    Abstract Aim, To analyse the gutta-percha filled area of C-shaped molar teeth root filled with the modified MicroSeal technique with reference to the radiographic features and the C-shaped canal configuration. Methodology, Twenty-three mandibular second molar teeth with C-shaped roots were classified according to their radiographic features as: type I , merging, type II , symmetrical and type III , asymmetrical. The canals were root filled using a modified technique of the MicroSeal system. Horizontal sections at intervals of 600 ,m were made 1 mm from the apex to the subpulpal floor level. The percentage of gutta-percha area from the apical, middle and coronal levels of the radiographic types was analysed using the Kruskal,Wallis test. Complementary analysis of the C-shaped canal configurations (C1, C2 and C3) determined from cross-sections from the apical third was performed in a similar way. Results, No significant differences were found between the radiographic types in terms of the percentage of gutta-percha area at any level (P > 0.05): apical third, type I: 77.04%, II: 70.48% and III: 77.13%, middle third, type I: 95.72%, II: 93.17%, III: 91.13% and coronal level, type I: 98.30%, II: 98.25%, III: 97.14%. Overall, the percentage of the filling material was lower in the apical third (P < 0.05). No significant differences were found between the C-shaped canal configurations apically; C1: 72.64%, C2: 79.62%, C3: 73.51% (P > 0.05). Conclusions, The percentage of area filled with gutta-percha was similar in the three radiographic types and canal configuration categories of C-shaped molars. These results show the difficulty of achieving predictable filling of the root canal system when this anatomical variation exists. In general, the apical third was less completely filled. [source]


    Fracture strength of bovine incisors after intra-radicular treatment with MTA in an experimental immature tooth model

    INTERNATIONAL ENDODONTIC JOURNAL, Issue 9 2007
    E. A. Bortoluzzi
    Abstract Aim, To evaluate, using an experimental immature tooth model, the fracture resistance of bovine incisors submitted to different reinforcement treatments with mineral trioxide aggregate (MTA). Methodology, An immature tooth model was created by sectioning the coronal and apical portions of 40 bovine incisors 8 mm above and 12 mm below the cementoenamel junction. The root canals were irrigated with 1.0% sodium hypochlorite. They were enlarged both coronally and apically using number 703 carbide burs (ISO: 500,104-168-007-021) and their internal diameter was standardized to 2.1 mm. The specimens were assigned to four groups (n = 10): GI-control (without filling); GII-apical MTA plug + filling with gutta-percha and endodontic sealer; GIII-filling with MTA; GIV-apical MTA plug + filling with MTA + metallic post (Reforpost I). A polyether impression material was used to simulate the periodontal ligament. The specimens were submitted to a compressive load at a crosshead speed of 0.5 mm min,1 in a servo-hydraulic universal testing machine (MTS 810) applied at 45° to the long axis of the tooth until failure. Data were submitted to statistical analysis by the Kruskal,Wallis test at 5% significance level. Results, GIV presented the highest fracture resistance (32.7N) and differed significantly from the other groups (P < 0.05). No statistically difference was found between GII (16.6N) and GIII (23.4N) (P > 0.05). GIII had a significantly higher fracture resistance than GI (P < 0.05). Conclusions, The use of MTA + metallic post as an intra-radicular reinforcement treatment increased the resistance to fracture of weakened bovine teeth in an experimental immature tooth model. [source]


    The effect of application time of EDTA and NaOCl on intracanal smear layer removal: an SEM analysis

    INTERNATIONAL ENDODONTIC JOURNAL, Issue 5 2005
    C. S. Teixeira
    Abstract Aim, To verify, under the scanning electron microscope (SEM), the influence of irrigation time with ethylenediaminetetraacetic acid (EDTA) and sodium hypochlorite (NaOCl) on intracanal smear layer removal. Methodology, Twenty-one extracted human permanent teeth with single straight root canals were included. The root canals of the teeth were instrumented and, at the end of preparation, were irrigated with 3 mL of 15% EDTA, followed by 3 mL of 1% NaOCl for 1 min (group 1), for 3 min (group 2), and for 5 min (group 3). The canals of teeth in group 4 (control) did not receive the final irrigation. The teeth were sectioned longitudinally and prepared for an SEM. The dentinal wall of cervical, middle and apical thirds was graded according to the amount of debris and smear layer remaining on the walls. The results were analysed using the Kruskal,Wallis and Conover,Inman tests. Results, In all the canals of experimental groups irrigation with EDTA and NaOCl completely removed the smear layer from the cervical and middle thirds. In the apical third, the dentine surface were partially covered, particularly in the teeth of group 1, where there was significantly more smear layer when compared with the other thirds in the same group (P < 0.007). However, the Kruskal,Wallis test showed overall that there were no significant differences between groups 1, 2 and 3 (P > 0.05). Conclusion, In this limited laboratory study, canal irrigation with EDTA and NaOCl for 1, 3 and 5 min were equally effective in removing the smear layer from the canal walls of straight roots. [source]


    Decalcification of root canal dentine by citric acid, EDTA and sodium citrate

    INTERNATIONAL ENDODONTIC JOURNAL, Issue 6 2004
    L. F. Machado-Silveiro
    Abstract Aim, To measure the demineralization capability of 1 and 10% citric acid, 10% sodium citrate and 17% EDTA during immersions of 5, 10 and 15 min on root canal dentine. Methodology, Crowns were sectioned from eight maxillary canines. The cementum was removed from the cervical third of the roots to expose the dentine. Canals were prepared using a handpiece-mounted Largo Peeso reamer. A 3-mm thick cross-sectional slice was obtained from the cervical third of each root. Each slice was sectioned into four equal parts. These specimens were assigned to one of four groups (n = 8) for the application of 1% citric acid, 10% citric acid, 10% sodium citrate or 17% EDTA. Each specimen underwent three successive 5-min immersions in each solution at room temperature. The solutions were not renewed between immersions. Two millimetres of solution were collected from the extracts and lanthanum oxide was added for the calcium reading by spectrophotometry. To compare the amounts of calcium removed by each solution, the Friedman test was used for the global comparison and the Wilcoxon test for paired comparisons. Differences between groups were evaluated using the Kruskal,Wallis test for the global comparison and Mann,Whitney test for paired comparisons. Results, Overall, 1 and 10% citric acid were more effective than EDTA or sodium citrate at the three immersion times (P < 0.001); 10% citric acid was more effective than 1% citric acid (P < 0.001). EDTA and 1 and 10% citric acid showed decreasing effectiveness with time, and the decrease was significant for citric acid at both concentrations (P < 0.001). Although sodium citrate removed little calcium during the three time periods, the small increase recorded was significant (P < 0.01). Conclusions, Citric acid at 10% was the most effective decalcifying agent, followed by 1% citric acid, 17% EDTA and 10% sodium citrate. [source]


    In vitro antimicrobial activity of several concentrations of sodium hypochlorite and chlorhexidine gluconate in the elimination of Enterococcus faecalis

    INTERNATIONAL ENDODONTIC JOURNAL, Issue 6 2001
    B. P. F. A. Gomes
    Abstract Aim The aim of this study was to assess, in vitro, the effectiveness of several concentrations of NaOCl (0.5%, 1%, 2.5%, 4% and 5.25%) and two forms of chlorhexidine gluconate (gel and liquid) in three concentrations (0.2%, 1% and 2%) in the elimination of E. faecalis. Methodology A broth dilution test using 24-well cell culture plates was performed and the time taken for the irrigants to kill bacterial cells was recorded. Isolated 24 h colonies of pure cultures of E. faecalis grown on 10% sheep blood plus Brain Heart Infusion (BHI) agar plates were suspended in sterile 0.85% NaCl solution. The cell suspension was adjusted spectrophotometrically to match the turbidity of a McFarland 0.5 scale. One mL of each tested substance was placed on the bottom of wells of 24-well cell culture plates (Corning, NY), including the control group (sterile saline). Six wells were used for each time period and irrigant concentration. Two mL of the bacterial suspension were ultrasonically mixed for 10 s with the irrigants and placed in contact with them for 10, 30, and 45 s; 1, 3, 5, 10, 20, and 30 min; and 1 and 2 h. After each period of time, 1 mL from each well was transferred to tubes containing 2 mL of freshly prepared BHI + neutralizers in order to prevent a residual action of the irrigants. All tubes were incubated at 37°C for 7 days. The tubes considered to have positive growth were those which presented medium turbidity during the incubation period. Data were analysed statistically by the Kruskal,Wallis test, with the level of significance set at P < 0.05. Results All irrigants were effective in killing E. faecalis, but at different times. Chlorhexidine in the liquid form at all concentrations tested (0.2%, 1% and 2%) and NaOCl (5.25%) were the most effective irrigants. However, the time required by 0.2% chlorhexidine liquid and 2% chlorhexidine gel to promote negative cultures was only 30 s and 1 min, respectively. Conclusions Even though all tested irrigants possessed antibacterial activity, the time required to eliminate E. faecalis depended on the concentration and type of irrigant used. [source]


    Ineffective Peripheral Tissue Perfusion: Clinical Validation in Patients With Hypertensive Cardiomiopathy

    INTERNATIONAL JOURNAL OF NURSING TERMINOLOGIES AND CLASSIFICATION, Issue 2 2006
    Rita de Cassia Gengo de Silva MS
    PURPOSE.,To validate defining characteristics of ineffective peripheral tissue perfusion using vasomotor function assessment. METHODS.,Twenty-four patients with hypertensive cardiomiopathy were evaluated for 18 defining characteristics of ineffective peripheral tissue perfusion and underwent vasomotor function assessment with induction of reactive hyperemia, intra-arterial infusion of acetylcholine, and pulse wave velocity measurement. The Student's t test and Kruskall,Wallis test were used to assess the significance of relationships between defining characteristics and vasomotor function data. FINDINGS.,Diminished lower extremity pulses were associated with diminished forearm blood flow during acetylcholine infusion; left ventricular overload, intermittent claudication, and diminished skin moisture were associated with elevated pulse wave velocity values. CONCLUSION.,The defining characteristics of ineffective peripheral tissue perfusion were highly associated with vasomotor function data as "gold standards" for that diagnosis. PRACTICE IMPLICATIONS.,Nurses should be able to accurately assess diminished lower extremity pulses, intermittent claudication, and diminished skin moisture as relevant characteristics of ineffective peripheral tissue perfusion in patients with hypertensive cardiomiopathy. Irrigation Tissulaire Périphérique Inefficace: Validation Clinique Chez les Patients Atteints de Cardiomyopathie Hypertensive BUT.,Valider les caractéristiques de Irrigation tissulaire périphérique inefficace en utilisant l'évaluation de la fonction vasomotrice. MÉTHODES.,Vingt-quatre patients souffrant de cardiomyopathie hypertensive furent évalués au regard des 18 caractéristiques du diagnostic Irrigation vasculaire périphérique inefficace et de la fonction vasomotrice par induction d'une hyperémie réactionnelle, la perfusion intra-artérielle d'acétylcholine, et la mesure de la vélocité de l'onde du pouls. Les tests "Student t et Kruskall,Wallis" furent utilisés pour déterminer l'importance des liens entre les caractéristiques et les valeurs de la fonction vasomotrice. RÉSULTATS.,La diminution des pulsations périphériques des membres inférieurs fut associée à une diminution du flot sanguin pendant la perfusion d'acétylcholine; une surcharge ventriculaire gauche, de la claudication intermittente et une diminution de l'hydratation de la peau furent associées à des valeurs élevées de la vélocité de l'onde du pouls. CONCLUSION.,,Les caractéristiques de Irrigation tissulaire périphérique inefficace qui furent associées de manière significative à la fonction vasomotrice peuvent être considérées comme les "étalons or" de ce diagnostic. IMPLICATIONS POUR LA PRATIQUE.,Les infirmières devraient être capables d'évaluer correctement la diminution des pouls périphériques, la claudication intermittente, et la diminution de l'hydratation de la peau, car ce sont des caractéristiques pertinentes de l'irrigation tissulaire périphérique inefficace chez les patients atteints de cardiomyopathie hypertensive. Translation by Cécile Boisvert, MSN, RN Perfusão Tissular Periférica Ineficaz: Validação Clínica em Pacientes com Miocardiopatia Hipertensiva PROPÓSITO.,Validar as caraterísticas definidoras do diagnóstico de perfusão tissular periférica ineficaz usando a avaliação da função vasomotora. MÉTODO.,Vinte e quatro pacientes com miocardiopatia hipertensiva foram avaliados segundo 18 características definidoras de perfusão tissular periférica ineficaz e submetidos a avaliação da função vasomotora por indução de hiperemia reativa, infusão intra-arterial de acetilcolina e por mensuração da velocidade da onda de pulso. Testes T de Student e de Kruskall,Wallis foram aplicados para avaliar a significância das relações entre as características definidoras e os dados da função vasomotora. RESULTADOS.,Diminuição de pulso nas extremidades inferiores foi associada com o menor fluxo de sangue no antebraço durante a infusão de acetilcolina; sobrecarga ventricular esquerda, claudicação intermitente e diminuição da hidratação da pele foram associados com valores elevados de velocidade de onda de pulso. CONCLUSÃO.,Quatro características definidoras de perfusão tissular periférica ineficaz foram altamente associadas com função vasomotora alterada como "padrão ouro" para este diagnóstico. IMPLICAÇÕES PARA A PRÁTICA.,As enfermeiras devem ser capazes de avaliar com precisão a diminuição dos pulsos das extremidades inferiores, claudicação intermitente e diminuição na hidratação da pele como características definidoras relevantes da perfusão tissular periférica ineficaz em pacientes com miocardiopatia hipertensiva. Translation by Alba Leite de Barros, PhD, RN Perfusión Tisular Periférica Inefectiva: Validación Clínica en Pacientes que Presentan Miocardiopatía Hipertensiva PROPÓSITO.,Validar las características definitorias del diagnóstico Perfusión tisular periférica inefectiva utilizando una valoración de la función vasomotora. METODOLOGÍA.,Veinticuatro pacientes diagnosticados de Miocardiopatía Hipertensiva fueron evaluados con respecto a las 18 características definitorias del diagnóstico Perfusión tisular periférica inefectiva y sometidos a una valoración de la función vasomotora con inducción de Hiperemia reactiva, infusión intra-arterial de acetilcolina, y medida de la velocidad de la onda del pulso. Se utilizaron los análisis estadísticos de t-Student y Kruskall,Wallis para valorar el significado de las relaciones entre las características definitorias y los datos obtenidos de la valoración de la función vasomotora. HALLAZGOS.,Durante la infusión de acetilcolina se detectó disminución de los pulsos en la extremidad inferior relacionado con la disminución del volumen de sangre en el antebrazo; la sobrecarga ventricular izquierda, claudicación intermitente y disminución de la hidratación de la piel fueron asociadas con la elevación de los valores de la velocidad de la onda del pulso. CONCLUSIÓN.,Las características definitorias del diagnóstico Perfusión tisular periférica inefectiva estaban fuertemente asociadas a los datos procedentes de la valoración de la función vasomotora identificándose como "estándares fundamentales" para este diagnóstico. IMPLICACIONES PARA LA PRÁCTICA.,Las enfermeras deberían ser capaces de valorar cuidadosamente la presencia de pulsos disminuidos en las extremidades inferiores, y la disminución de la hidratación de la piel ya que son características relevantes del diagnóstico Perfusión tisular periférica inefectiva en pacientes que presentan Miocardiopatía Hipertensiva. Translation by Adolf Guirao, RN [source]


    Tuscany autochthonous cattle breeds: an original genetic resource investigated by AFLP markers

    JOURNAL OF ANIMAL BREEDING AND GENETICS, Issue 1 2006
    R. Negrini
    Summary The aim of this study was to assess the genetic diversity of four autochthonous cattle breeds of Tuscany and their relationships in comparison with Italian Friesian and Italian Brown, using amplified fragment length polymorphism markers. A total of 212 individuals were genotyped with three primer combinations generating 102 polymorphic markers. Average expected heterozygosity ranged from 0.23 in Mucca Pisana to 0.26 in Chianina, Italian Friesian, Italian Brown and Maremmana. The differences resulted not significant (Kruskall,Wallis test, p = 0.416). Gst-B index revealed that 86% of the total genetic variance is retained within population and only 14% is accounted by the between populations component. Multivariate analysis at individual and population level indicated that: (i) Calvana and Chianina are quite separate from the other breeds as an effect of the bottleneck experienced or as a signature of different origin; (ii) Podolian, Maremmana and Italian Brown clustered with the double purpose Mucca Pisana, revealing their contribution to its admixed genetic make up; (iii) Italian Friesian behaved always as out group. The ,analysis of molecular variance' recovered a significant subdivision clustering the six populations into three groups: Italian Friesian and Italian Brown versus Maremmana and Mucca Pisana versus Chianina and Calvana (6% of the total variance). [source]


    Relationships between nurse care-giving behaviours and preterm infant responses during bathing: a preliminary study

    JOURNAL OF CLINICAL NURSING, Issue 1-2 2010
    Jen-Jiuan Liaw
    Aims., The purpose of this study was to explore the relationships between specific nurse care-giving behaviours and preterm infant behavioural responses during bathing and to identify nurse behaviours associated with infant ,stress'. Background., Although recent advances in medical technology have improved neonatal intensive care, the high mortality and morbidity rates in preterm infants have not decreased proportionally. As caregivers strive to reduce infant mortality and morbidity, a factor for consideration is which caregiver behaviours are associated with preterm infant well-being. Design., A descriptive correlational design. Method., Convenience samples of 24 preterm infants and 12 nurses were recruited. A total of 120 baths were videotaped. Infant and nurse behaviours were measured using the coding schemes developed by the researchers. Pearson coefficient correlation, non-parametric Kruskal,Wallis test, t -test and generalised linear models were methods for data analysis. Results., As nurses provided more support, stress was reduced in the infants, and their self-regulation during the bath was enhanced especially by the use of ,containment' and ,positional support'. Conversely, non-therapeutic caregiver behaviours including ,rapid and rough handling' of the baby, ,chatting with other people' and ,inappropriate handling' increased infant ,stress' during the bath. Conclusion., The findings provide new information about the link between care-giving and infant responses and how caregivers can better interact with preterm infants during a very sensitive period of brain development. Relevance to clinical practice., How nurses take care of the preterm infants influences their responses to care-giving stimuli. To interact better with the infant during care-giving procedures, nurses need to provide more supportive care-giving behaviours especially ,position support' and ,containment' based on the infant's needs, and avoid care-giving that may be too rough and occur too quickly without attending the baby's stressful signals, positioning the baby in hyperextension posture, or chatting with other people during procedures. [source]


    Fatigue in multiple sclerosis patients

    JOURNAL OF CLINICAL NURSING, Issue 9 2009
    Mukadder Mollao
    Aim., This study aimed to describe fatigue and the factors that affect fatigue in people with multiple sclerosis. Background., Fatigue is the most common symptom and has the greatest effect on multiple sclerosis patients' activities of daily living. There is limited understanding of the level of fatigue experienced by people with multiple sclerosis, with research currently limited to other symptoms and problems related to multiple sclerosis. Design., This research was conducted as a descriptive survey. Methods., The study involved 120 people with multiple sclerosis. The data were collected with a Patient Questionnaire and a Visual Analogue Scale for Fatigue (VAS-F). Variance analysis, Mann,Whitney U -test and Kruskal,Wallis test were used in the data analysis. Results., All of the individuals in the sample experienced fatigue. Their fatigue was also affected by factors such as age, gender, education, marital status, number of children, occupation and duration of illness. In addition, the situations with the greatest effect on their fatigue were taking a hot bath/shower, hot/humid weather, stress, infection and other illnesses causing fever, disturbance in sleep pattern, increase in daily activities and exercise. Conclusions., Fatigue is a symptom that has a significant effect on the daily lives of people with multiple sclerosis. Accordingly, it is recommended that factors affecting fatigue in people with multiple sclerosis be evaluated and that education programmes directed at how to control these factors. Relevance to clinical practice., The determination of factors affecting fatigue is important for multiple sclerosis individuals' ability to cope with fatigue and keep it under control. To be able to accomplish this it is necessary for health care personnel, the family and friends to work together. [source]


    Significance of Periodontal Risk Assessment in the recurrence of periodontitis and tooth loss

    JOURNAL OF CLINICAL PERIODONTOLOGY, Issue 2 2010
    G. Matuliene
    Matuliene G, Studer R, Lang NP, Schmidlin K, Pjetursson BE, Salvi GE, Brägger U, Zwahlen M. Significance of Periodontal Risk Assessment on the recurrence of periodontitis and tooth loss. J Clin Periodontol 2010; 37: 191,199. doi: 10.1111/j.1600-051X.2009.01508.x. Abstract Aim: To investigate the association of the Periodontal Risk Assessment (PRA) model categories with periodontitis recurrence and tooth loss during supportive periodontal therapy (SPT) and to explore the role of patient compliance. Material and Methods: In a retrospective cohort, PRA was performed for 160 patients after active periodontal therapy (APT) and after 9.5 ± 4.5 years of SPT. The recurrence of periodontitis and tooth loss were analysed according to the patient's risk profile (low, moderate or high) after APT and compliance with SPT. The association of risk factors with tooth loss and recurrence of periodontitis was investigated using logistic regression analysis. Results: In 18.2% of patients with a low-risk profile, in 42.2% of patients with a moderate-risk profile and in 49.2% of patients with a high-risk profile after APT, periodontitis recurred. During SPT, 1.61 ± 2.8 teeth/patient were lost. High-risk profile patients lost significantly more teeth (2.59 ± 3.9) than patients with moderate- (1.02 ± 1.8) or low-risk profiles (1.18 ± 1.9) (Kruskal,Wallis test, p=0.0229). Patients with erratic compliance lost significantly (Kruskal,Wallis test, p=0.0067) more teeth (3.11 ± 4.5) than patients compliant with SPT (1.07 ± 1.6). Conclusions: In multivariate logistic regression analysis, a high-risk patient profile according to the PRA model at the end of APT was associated with recurrence of periodontitis. Another significant factor for recurrence of periodontitis was an SPT duration of more than 10 years. [source]


    Evaluation of the relationship between smoking during pregnancy and subgingival microbiota

    JOURNAL OF CLINICAL PERIODONTOLOGY, Issue 1 2005
    Nurcan Buduneli
    Abstract Background: Numerous studies have shown that smoking negatively affects periodontal health. Hormonal changes, which occur during pregnancy have also been reported to have adverse effects on the periodontal tissues or indirectly through alterations in the subgingival bacterial flora. At present, no knowledge exists concerning possible effects of smoking on the composition of subgingival plaque in pregnancy. The purpose of the present study was to evaluate the effects of smoking during pregnancy on the subgingival plaque bacteria most commonly associated with periodontal disease. Methods: A total number of 181 women were examined within 72 h post-partum. Smoking status was recorded by means of a self-reported questionnaire and the study population was divided into three groups; non-smokers, light smokers, and heavy smokers. In each woman, two subgingival plaque samples were obtained from mesio- or disto-buccal aspect of randomly selected one molar and one incisor tooth by sterile paperpoints. Clinical periodontal recordings comprising presence of dental plaque, bleeding on probing (BOP), and probing pocket depth (PPD) were performed at six sites per each tooth at all teeth. Plaque samples were analysed by checkerboard DNA,DNA hybridization with respect to 12 bacterial species. In all analyses, the individual subject was the computational unit. Thus, mean values for all clinical parameters were calculated and bacterial scores from each individual sample were averaged. Statistical methods included ,2 test, Kruskal,Wallis test and Mann,Whitney U -test. Results: Mean ages were similar in the study groups. Plaque, BOP and PPD recordings were lower in the heavy-smoker group, but the differences were not statistically significant (p>0.05). The detection rates and bacterial loads of the specific subgingival bacteria exhibited no significant differences between the groups. No correlation could be found between smoking status and detection rates and bacterial loads of various bacterial species. Conclusion: The present findings suggest that smoking during pregnancy does not have a significant effect on the composition of subgingival plaque bacteria. [source]


    In vitro evaluation of novel low abrasive air polishing powders

    JOURNAL OF CLINICAL PERIODONTOLOGY, Issue 1 2003
    G. J. Petersilka
    Abstract Aim of the study: Though efficient in stain and plaque removal, air polishing is highly abrasive on root cementum or dentin even if working parameters are adjusted to minimize damage. As abrasiveness is also influenced by the physical properties of the powders used, the aim of the study was to evaluate the safety of novel low abrasive air polishing powders in vitro. Material and methods: Using four novel air polishing powders (A, B, C and D) and a standard sodium bicarbonate (NaHCO3) powder, roots of 126 extracted teeth were air polished under standardized conditions at various working parameter combinations (distance: 2 mm, 4 mm and 6 mm; powder and water setting: low, medium and high) at an angulation of 90° for 20 s. Instrumentation was performed in triplicate; resulting root defects were quantified laser-optically. Results: Mean defect depths after application of powders A, B, C and D were significantly lower than with standard powder (A: 17.9 ± 10.9 µm, B: 48.2 ± 32.7 µm, C: 92.5 ± 57.9 µm, D: 33.9 ± 19.6 µm, NaHCO3: 163.1 ± 71.1 µm) (Kruskal,Wallis test). Among the experimental powders, D was transported most reliably in the air polishing unit and allowed complete removal of disclosed plaque as assessed on freshly extracted teeth. Conclusion: The novel air polishing powder D is of low abrasiveness to root cementum and dentin while being effective in removing dental plaque. Thus, it may be useful for safe and efficient plaque removal on exposed root surfaces. [source]


    Direct Dentin Bonding Technique Sensitivity When Using Air/Suction Drying Steps

    JOURNAL OF ESTHETIC AND RESTORATIVE DENTISTRY, Issue 2 2008
    PASCAL MAGNE DMD
    ABSTRACT Statement of Problem:, Moisture control before and after application of the primer/adhesive components of etch-and-rinse dentin bonding agents is usually achieved using a stream of air delivered by an air syringe. Suction drying with a suction tip is a common alternative for moisture control, but data about the use of suction drying instead of the air syringe is scarce or nonexistent. Purpose:, The purpose of this study was to compare the dentin microtensile bond strength (MTBS) using either the air syringe or the suction tip to control the amount of moisture. Materials and Methods:, Fifteen freshly extracted human molars were divided randomly into three groups of five. A three-step etch-and-rinse dentin bonding agent (OptiBond FL) was used. Group 1 was the control group and utilized air drying alone (with an air syringe) during the placement of the dentin adhesive on the ground-flat occlusal dentin surface. Group 2 also used air drying alone, but teeth were prepared with a standardized MOD cavity. Group 3 utilized suction drying alone in the standardized MOD cavity. All teeth were restored with 1.5-mm-thick horizontal increments of composite resin (Filtek Z100). Specimens were stored in water for 24 hours, then prepared for a nontrimming MTBS test. Bond strength data were analyzed with a Kruskal,Wallis test at p < 0.05. Specimens were also evaluated for mode of fracture and interface characterization using scanning electron microscope (SEM) analysis. Results:, The mean MTBSs were not statistically different from one another (p = 0.54) at 54.0 MPa (air-drying, flat dentin), 53.4 MPa (air-drying, MOD), and 49.2 MPa (suction drying, MOD). Microscopic evaluation of failure modes indicated that most failures were interfacial. Failed interfaces, when analyzed under SEM, appeared typically mixed with areas of failed adhesive resin and areas of cohesively failed dentin. Conclusions:, There are no differences in MTBS to human dentin using either the air syringe or the suction tip to control the amount of moisture. The conventional three-step dentin bonding agent used in the present study not only proved insensitive to the moisture-control method but also to the effect of increased polymerization shrinkage stress (ground-flat versus MOD preparation). CLINICAL SIGNIFICANCE Although the effect of common errors on the performance of total-etch adhesives has been investigated, data about the use of suction drying instead of an air syringe is scarce or nonexistent. The present study demonstrated that both the air syringe and the suction tip can be used to control moisture when using etch-and-rinse dentin bonding agents. The conventional three-step dentin bonding agent tested, OptiBond FL, demonstrated low technique sensitivity. [source]


    The effect of three different periodontal pre-treatment procedures on the success of telescopic removable partial dentures

    JOURNAL OF ORAL REHABILITATION, Issue 4 2003
    R. Polansky
    summary, In this prospective study, 120 teeth consisting of maxillary and mandibular canines and premolars were divided into three groups each containing 40 teeth. The teeth were assigned randomly in quadrants to three different periodontal treatment protocols. The first group was treated with professional prophylaxis only. The second group received additional deep scaling. With the third group, additional surgical periodontal flap surgery and scaling was performed. Both papillary bleeding index (PBI) and probing depth (PD) were evaluated before, during and after treatment. During the subsequent prosthetic treatment phase all teeth were then used as telescope abutments supporting a removable prosthesis. The documentation of the attachment level (AL) was then used as a clinical parameter. One year after the incorporation of telescopic removable partial dentures (RPDs), PD, PBI and AL were again evaluated. The resulting periodontal parameters were compared between the different groups using the general linear model (GLM) repeated measures and the Kruskal,Wallis test for non-parametric variables. Differences within the three treatment groups were determined using the t -test, e.g. the Wilcoxon test for dependent variables (P < 0·05). A significant decrease in inflammatory indices (PBI) was found for all types of periodontal treatment (P < 0·03 for all groups). Additionally, the reduction in PD was significant for all of the three groups (P < 0·001 for all groups). The greatest reduction in PD was observed in the group in which a surgical approach was used. Evaluation of the attachment level after the incorporation of the telescopic RPDs showed that tooth position did not influence the periodontal prognosis and that the use of telescopic RPDs exerted no ascertainable negative influence on the periodontium of the abutment teeth. [source]


    Tensile bond strengths of four different dentin adhesives on irradiated and non-irradiated human dentin in vitro

    JOURNAL OF ORAL REHABILITATION, Issue 9 2001
    C. R. Gernhardt
    This study evaluated the influence of irradiation on dentin bond strength. Sixty irradiated and 60 non-irradiated human third molars were used. The irradiation dose of 60 Gy was fractionally applied over 6 weeks (2 Gy day,1, 5 days week,1). All teeth were prepared in a special manner allowing the simulation of intra-pulpal pressure and dentin perfusion. Dentin specimens with a thickness of 2·0 mm were obtained under standardized conditions. The specimens were randomly assigned to four experimental groups. Tensile bond strength of four different dentin bonding agents (ScotchbondÔ 1, Solobond Plus®, Prime&BondÔ 2·1 and Syntac®) was evaluated using an Instron Universal testing machine. Pairwise comparison did not show any significant differences between the irradiated and non-irradiated groups. The influence of the different dentin adhesives was significant (P=0·0001; ANOVA). Compared with Solobond Plus® and Prime&BondÔ 2·1, the use of ScotchbondÔ 1 resulted in a significantly higher tensile bond strength in non-irradiated specimen (P< 0·05; closed test procedure based on Kruskal,Wallis test). Within the limitations of an in vitro study, it can be concluded that adhesive restoration procedures can be successfully used in patients irradiated for cancer of the head and neck. [source]


    Effect of cavity varnish, amalgam liner or dentin bonding agents on the marginal leakage of amalgam restorations

    JOURNAL OF ORAL REHABILITATION, Issue 5 2001
    S. Belli
    The purpose of this in vitro study was to compare marginal leakage of Class II amalgam restorations lined with different agents (two new generation dentin bonding systems, a cavity varnish and an amalgam liner). Forty freshly extracted human molar teeth were divided into five groups. Class II preparations were prepared in the mesial and distal surfaces of each molar. While the cavities in two groups were lined with two new generation bonding systems, the other two groups were treated with an amalgam lining material and a cavity varnish. Fifth group was used as control, without any lining. Amalgam* was hand-condensed into each preparation. Specimens were thermocycled, stained and sectioned. Microleakage was graded using a stereomicroscope. Mean microleakage scores for occlusal and cervical margins were calculated and analised. For the leakage values on occlusal margins, Kruskal,Wallis test indicated no significant difference in all groups. For the leakage values on cervical margins, Kruskal,Wallis test indicated significant difference in four groups when compared with controls (P < 0·001). On the other hand, there was no significant difference between the occlusal and cervical leakage values in each group. [source]


    Expression of periodontal interleukin-6 protein is increased across patients with neither periodontal disease nor diabetes, patients with periodontal disease alone and patients with both diseases

    JOURNAL OF PERIODONTAL RESEARCH, Issue 5 2010
    J. H. Ross
    Ross JH, Hardy DC, Schuyler CA, Slate EH, Mize TW, Huang Y. Expression of periodontal interleukin-6 protein is increased across patients with neither periodontal disease nor diabetes, patients with periodontal disease alone and patients with both diseases. J Periodont Res 2010; 45: 688,694. © 2010 John Wiley & Sons A/S Background and Objective:, Epidemiological studies have established that patients with diabetes have an increased prevalence and severity of periodontal disease. Interleukin (IL)-6, a multifunctional cytokine, plays a role in the tissue inflammation that characterizes periodontal disease. Our recent study has shown a trend of increase in periodontal IL-6 expression at the mRNA level across patients with neither periodontal disease nor diabetes, patients with periodontal disease alone and patients with both diseases. However, the periodontal IL-6 expression at the protein level in these patients has not been investigated. Material and Methods:, Periodontal tissue specimens were collected from eight patients without periodontal disease and diabetes (group 1), from 17 patients with periodontal disease alone (group 2) and from 10 patients with both periodontal disease and diabetes (group 3). The frozen sections were prepared from these tissue specimens and IL-6 protein expression was detected and quantified. Results:, The nonparametric Kruskal,Wallis test showed that the difference in IL-6 protein levels among the three groups was statistically significant (p = 0.035). Nonparametric analysis using the Jonckheere,Terpstra test showed a tendency of increase in periodontal IL-6 protein levels across group 1 to group 2 to group 3 (p = 0.006). Parametric analysis of variance (ANOVA) on IL-6 protein levels showed that neither age nor gender significantly affected the difference of IL-6 levels among the groups. Conclusion:, Periodontal IL-6 expression at the protein level is increased across patients with neither periodontal disease nor diabetes, patients with periodontal disease alone and patients with both diseases. [source]


    Factors affecting human supragingival biofilm composition.

    JOURNAL OF PERIODONTAL RESEARCH, Issue 4 2009

    Background and Objective:, Little is known regarding the factors that affect the microbial composition of supragingival biofilms. This study was designed to test the hypothesis that tooth location affects the microbial composition of supragingival plaque beyond the effect due to plaque mass as reflected by total DNA probe count. Material and Methods:, Supragingival plaque samples were taken from the mesiobuccal aspect of each tooth in 187 subjects (n = 4745 samples). All samples were individually analyzed for their content of 40 bacterial species using checkerboard DNA,DNA hybridization. Significance of differences in mean species counts and proportions were determined among tooth surfaces and six tooth type categories: molars, bicuspids, incisors/canines in the mandible and maxilla separately using the Kruskal,Wallis test. Stepwise multiple linear regression was employed to examine the relationship between species proportions and total DNA probe count, tooth location, periodontal and smoking status, age and sex. Results:, All species differed significantly among tooth types and among the six tooth categories. Higher plaque levels were seen on molars and lower incisors. Some differences observed between tooth types could be partly explained by the level of plaque. Teeth with high plaque mass exhibited high levels of Capnocytophaga gingivalis, Actinomyces naeslundii genospecies 2, Campylobacter rectus and Campylobacter showae. However, certain species, such as Veillonella parvula and Streptococcus sanguinis, differed significantly at different tooth locations despite similarities in plaque mass. Twenty of the test species exhibited a significant association with tooth location after adjusting for total DNA probe count and subject level factors. Conclusion:, While plaque mass was associated with differences in proportions of many species in supragingival biofilms, tooth location also was strongly associated with species proportions in both univariate and multivariate analyses. [source]


    Nurses' ethical perceptions about coercion

    JOURNAL OF PSYCHIATRIC & MENTAL HEALTH NURSING, Issue 4 2004
    M. LIND mscnrn
    Purpose of the study: The purpose of this study was to describe Finnish psychiatric nurses' ethical perceptions about coercive measures in acute psychiatric setting. Methods: The data were collected with a questionnaire developed for this study. The sample included 170 Finnish psychiatric nurses on acute wards in five psychiatric hospitals. The data were analysed using frequency and percentage distributions, mean and standard deviations. The internal consistency of the instrument was explored with Cronbach's alpha. The association between the background variables and the sum score of the items of the questionnaire was tested with Mann,Whitney U -test and Kruskal,Wallis test. The open-ended question was analysed with content analysis. Results: Some psychiatric nurses perceived coercive measures as ethically problematic. In particular, the implementation of forced medication (18%), four-point restraints (16%) and patient seclusion (11%) were perceived as ethically problematic. Female nurses and nurses who worked on closed wards perceived the measures to be more problematic than male nurses and nurses who did not work on closed wards. Conclusion: In Finland, special attention has been paid to ethical questions related to the care of psychiatric patients and to the enhancement of patients' rights, yet the majority of the nurses participating in the survey did not perceive coercive measures as ethically problematic. More research on this issue as well as further education of the personnel and more extensive teaching of ethics in nursing schools are needed to support the ability of the psychiatric personnel to identify ethically problematic situations. In addition, it is important to consider new measures for generating genuine moral reflection among the personnel on the usage of coercive measures as well as on their effectiveness and legitimacy in the psychiatric care. [source]


    Patients' satisfaction with outpatient psychiatric care

    JOURNAL OF PSYCHIATRIC & MENTAL HEALTH NURSING, Issue 2 2003
    U. SIPONEN
    The purpose of this study was to describe patient satisfaction with outpatient psychiatric care in two community care clinics in Finland. Data were collected using a structured questionnaire from 300 outpatients between February and March 2000. A total of 171 patients returned completed questionnaires (response rate 57%). The data analysis was based on descriptive statistics, chi-square test, the Mann,Whitney U -test and the Kruskal,Wallis test. Item homogeneity was analysed using Cronbach alpha coefficient. The results showed that patient satisfaction was highest in areas pertaining to staff and care discussions, and lowest in areas pertaining to information. Patients who considered the wait for treatment to be too long were more dissatisfied with staff, their chance of influencing their own care, and the help they received, compared with patients who considered the wait to be reasonable in length. We can conclude that although patients are quite satisfied with their outpatient treatment in general, the patient information process is not at a satisfactory level at outpatient psychiatric clinics. In the future, more emphasis should be put on developing more innovative methods to increase psychiatric patients' knowledge level regarding their own illness and treatment. [source]


    Are you an invited speaker?

    JOURNAL OF THE AMERICAN SOCIETY FOR INFORMATION SCIENCE AND TECHNOLOGY, Issue 6 2009
    A bibliometric analysis of elite groups for scholarly events in bioinformatics
    Participating in scholarly events (e.g., conferences, workshops, etc.) as an elite-group member such as an organizing committee chair or member, program committee chair or member, session chair, invited speaker, or award winner is beneficial to a researcher's career development. The objective of this study is to investigate whether elite-group membership for scholarly events is representative of scholars' prominence, and which elite group is the most prestigious. We collected data about 15 global (excluding regional) bioinformatics scholarly events held in 2007. We sampled (via stratified random sampling) participants from elite groups in each event. Then, bibliometric indicators (total citations and h index) of seven elite groups and a non-elite group, consisting of authors who submitted at least one paper to an event but were not included in any elite group, were observed using the Scopus Citation Tracker. The Kruskal,Wallis test was performed to examine the differences among the eight groups. Multiple comparison tests (Dwass, Steel, Critchlow,Fligner) were conducted as follow-up procedures. The experimental results reveal that scholars in an elite group have better performance in bibliometric indicators than do others. Among the elite groups, the invited speaker group has statistically significantly the best performance while the other elite-group types are not significantly distinguishable. From this analysis, we confirm that elite-group membership in scholarly events, at least in the field of bioinformatics, can be utilized as an alternative marker for a scholar's prominence, with invited speaker being the most important prominence indicator among the elite groups. [source]


    Tensile bond strength of a flowable composite resin to ER:YAG-laser-treated dentin,

    LASERS IN SURGERY AND MEDICINE, Issue 5 2005
    Juliana Donadio-Moura MSD
    Abstract Background and Objectives This in vitro study evaluated the influence of a flowable composite resin (FCR) on the tensile bond strength of resin to dentin treated with the Er:YAG Laser (L) and diamond bur (DB). Study Design/Materials and Methods Ninety dentin surfaces obtained from 45 third molars were ground and randomly divided into six groups (n,=,15): G1,DB, G2,DB+FCR, G3,L (100 mJ, 10 Hz, 37.04 J/cm2), G4,L (100 mJ, 10 Hz, 37.04 J/cm2)+FCR, G5,L (250 mJ, 2 Hz, 92.60 J/cm2), and G6,L (250 mJ, 2 Hz, 92.60 J/cm2)+FCR. After surface etching with 37% phosphoric acid and the application of an adhesive system, inverted conical specimens were prepared with a hybrid composite resin. In groups G2, G4, and G6 a FCR was placed before the hybrid composite resin. After 24 hours-storage in distilled water, the tensile test was performed in a universal testing machine (0.5 mm/minute, 500 N). Results Data were submitted to Kruskal Wallis test (P,=,0.01). The mean bond strength values (MPa±SD) were: G1,13.54 (±2.99), G2,14.67 (±2.32), G3,9.49 (±3.09), G4,14.60 (±2.76), G5,8.97 (±3.89), and G6,13.02 (±2.18). Groups G1 and G2 presented the highest bond strength values, which were statistically similar to those of G4 and G6. The groups treated with laser and without the FCR (G3 and G5) showed the lowest shear bond strength values. Conclusions FCR can increase the adhesion to dentin treated with Er:YAG laser within different parameters. © 2005 Wiley-Liss, Inc. [source]


    Premedication with melatonin vs midazolam in anxious children

    PEDIATRIC ANESTHESIA, Issue 7 2008
    BERRIN ISIK MD
    Summary Aim:, Failure of dental treatment caused by anxiety is a common problem in children. Oral midazolam has been the most commonly used premedication for pediatric patient but the use of midazolam may be associated with paradoxical reactions in children. Melatonin may induce a natural sleepiness and improve sedation. We have investigated premedication with melatonin compared with midazolam in children under nitrous oxide/oxygen (N2O/O2) sedation for dental treatment. Methods:, In a randomized study, 60 children received either 3 mg of melatonin [Melatonina (3 mg®) 60 min before the procedure (n = 15); group I], 0.5 mg·kg,1 melatonin 60 min before the procedure (n = 15; group II), 0.75 mg·kg,1 midazolam [Dormicum (15 mg/3 ml ®) 15 min before the procedure (n = 15); group III] or 3 ml of 0.09 NaCl 15 min (n = 7) or 60 min before the procedure (n = 8; group IV) orally. The children were sedated with 40/60% N2O/O2 inhalation. The heart rate and O2 saturation were monitored during the treatment period. The level of sedation was assessed according to the Ramsay Sedation Scale. The children's sedation success during dental treatment was classified. The sedation success and other sedation-related events recorded. Comparisons among the four groups were made using one-way anova or Kruskal,Wallis test, and if any significant differences were noted, the Tukey's HSD or Mann,Whitney U -test were used for intergroup comparisons. All differences were considered significant at P < 0.05. Results:, The evaluation of sedation success was as follows: group I: satisfactory (n = 1), average satisfactory (n = 4), and unsatisfactory (n = 10); group II: satisfactory (n = 2), average satisfactory (n = 3), and unsatisfactory (n = 10); group III: satisfactory (n = 9), average satisfactory (n = 6); and group IV: satisfactory (n = 1), average satisfactory (n = 3), and unsatisfactory (n = 11). Conclusion:, In these doses and clinical conditions, melatonin was similar to that of placebo and did not contribute to N2O/O2 sedation of anxious children. [source]


    Rapid emergence does not explain agitation following sevoflurane anaesthesia in infants and children: a comparison with propofol

    PEDIATRIC ANESTHESIA, Issue 1 2003
    Ira Todd Cohen MD
    Summary Background: Emergence agitation in children is frequently associated with the use of the new highly insoluble volatile anaesthetics. Rapid emergence has been cited as one of the possible causes. Propofol also permits rapid emergence from general anaesthesia but is not associated with agitation. Methods: The emergence characteristics of children receiving sevoflurane and propofol anaesthesia were examined. After induction with sevoflurane, 53 children, aged 2,36 months, who were undergoing ambulatory surgery, were randomized to receive maintenance anaesthesia with either sevoflurane or propofol. Introperative analgesia with either 2 µg·kg,1 of intravenous fentanyl or a caudal block with 0.25% bupivacaine was supplied according to surgical procedure. An observer blinded to anaesthetic technique recorded the time to achieve extubation and recovery and assessed emergence behaviour. Data were analysed using Wilcoxon scores, Kruskal,Wallis test, chi-square and multiple regression analysis. Results: The results showed that the time to extubation and recovery were similar between the two study groups, but that emergence agitation was significantly higher in the sevoflurane group compared with the propofol group. No relationship between analgesic technique and agitation scores was found. Conclusions: Although both sevoflurane and propofol allow for rapid emergence from general anaesthesia, only sevoflurane is associated with a high incidence of emergence agitation in infants and young children. Rapid emergence does not fully explain this phenomena. [source]


    Liver histology after current intensified therapy for childhood acute lymphoblastic leukemia: microvesicular fatty change and siderosis are the main findings

    PEDIATRIC BLOOD & CANCER, Issue 3 2003
    Päivi Halonen MD
    Abstract Background During modern intensified therapy for childhood acute lymphoblastic leukemia (ALL) serum liver enzymes reach fairly high levels. Since no recent data on liver histopathology after therapy are available, we conducted a study of the subject. Procedure Liver biopsy specimens were evaluated and serum liver function tests and lipid profiles measured from 27 consecutive children, aged 3.5,17.6 years, treated according to the regimens for standard (SR) and intermediate risk (IR) ALL. Results None of the patients had entirely normal liver histology. Fatty infiltration was detected in 25 out of 27 (93%) and siderosis in 19 out of 27 patients (70%). Fourteen (52%) had both. Three (11%) also had mild portal and/or periportal fibrosis in addition to fatty change and siderosis. Fatty change was mainly microvesicular. Siderosis was in most cases grade II/IV to III/IV (in 16/19 or 84%). No hepatitis or cirrhosis was found. Serum total and LDL-cholesterol levels were higher in the patients with fibrosis than in the patients with fatty change (P,=,0.036, P,=,0.042) or with siderosis,±,fatty change (P,=,0.036, P,=,0.042). In serial ALT measurements a value of 300 U/L or more was oftener reached in the fibrosis than in the fatty change or siderosis groups (in 33 vs. in 12 or in 4% of the measurements, respectively, P,=,0.014, in Kruskall,Wallis test). Conclusions Microvesicular fatty change and siderosis are the main liver findings after current therapy for childhood ALL. Fibrosis occurs rarely. High values in serial serum ALT measurements repeatedly or a disturbed serum lipid profile may facilitate decisions about the need for a liver biopsy. Med Pediatr Oncol 2003;40:148,154. © 2003 Wiley-Liss, Inc. [source]


    Self-perception levels of mothers dealing with infant care problems for babies 0,12 months old

    PEDIATRICS INTERNATIONAL, Issue 5 2009
    nar Bayhan
    Abstract Background:, Babies need the presence of an adult, especially their mothers, from the moment they are born in order to have their needs fulfilled. The significance of the care, particularly during the newborn and the babyhood period, increases gradually as the children grow older. The adequate and efficient fulfillment of needs during the newborn and babyhood period are fundamental in terms of child development. On the other hand, many mothers don't know what to do about problematic situations related to infant care that they might encounter when they have a newborn baby. Methods:, The self-perception of 864 mothers, in various educational level groups, with 432 male and 432 female babies, was analyzed in regards to dealing with problems that arise related to infant care. A questionnaire, developed by Pridham and Chang (1991), was filled out during interviews with the mothers. The analyses of the data obtained as the result of the study were evaluated with the Kruskal,Wallis test while the statistically significant findings were dually compared using the Mann,Whitney test. Results:, At the conclusion of the study it was determined that the gender of the baby did not effect the mother's self-perception during problem solving, whereas their educational levels created remarkable differences amongst their responses. [source]


    The recovery of walking ability and subclassification of stroke

    PHYSIOTHERAPY RESEARCH INTERNATIONAL, Issue 3 2001
    Gillian Baer MSc, MCSP
    Abstract Background and Purpose The recovery of walking after a stroke is a key functional goal for many patients. Reports vary, but approximately 50,80% of patients will regain some degree of walking ability following stroke (Skilbeck et al., 1983). There are few data available to show whether different subclassifications of stroke have distinct patterns of gait recovery. The present paper describes the pattern of walking recovery in a population of stroke patients classified according to the Oxfordshire Community Stroke Project classification (Bamford et al., 1991). Method A prospective observational study. Stroke patients (n=238) admitted to the inpatient Stroke Rehabilitation Unit at the Western General Hospital, Edinburgh were initially included, with data for 185 patients ultimately available for analysis. Standardized measures of recovery of 10 steps and a 10-metre walk were used routinely to examine recovery time of walking ability. The main outcome measures consisted of days taken to achieve a 10-step walk, days to achieve a 10-metre walk, and initial and discharge gait velocity over 10 metres. Results Eighty-nine per cent of the sample (n=164) achieved a 10-step walk in a median time of five days and a 10-metre walk in eight days. The median initial gait velocity was 0.45 m/s which improved by discharge to 0.55 m/s. Further analysis by subgroup revealed that subjects sustaining a partial anterior circulation infarct, lacunar infarct or posterior circulation infarct recovered significantly more quickly than those subjects with a total anterior circulation infarct (Kruskal Wallis test for days to achieve 10 steps (H = 22.524, N = 164, df = 3) p<0.001; Kruskal Wallis test for days to achieve a 10-metre walk (H = 22.586, N = 164, df = 3) p<0.001. Conclusions An hierarchical pattern of recovery of gait was observed with definite variation between the subclassifications of stroke. It is suggested that further work needs to be undertaken to identify more accurately the factors that may influence the recovery of walking following stroke. Copyright © 2001 Whurr Publishers Ltd. [source]


    Comparative mechanical property characterization of three indirect composite resin materials compared with two direct composites

    POLYMERS FOR ADVANCED TECHNOLOGIES, Issue 6 2003
    Dr. Figen Demirel
    Abstract Various new indirect composite materials have been developed with required advantages. In this study three indirect composite material (Artglass, Belleglass HP, Targis) were tested for flexural strength, fracture toughness, wear resistance and hardness against Filtek P60 and Z-100. Five specimens of each material were fabricated according to the manufacturer's directions. The flexural strength and fracture toughness was measured using the bending test. The wear test was performed to accelerated wear in a toothbrushing apparatus. Vickers hardness was measured for each of the tested materials. The statistical tests used for flexural strength, fracture toughness, wear and hardness were One-way ANOVA and Kruskal,Wallis test. The level of statistical significance chosen was p,=,0.05. Results of the study showed that Filtek P60 was superior to the other composites in all tests. Significant differences were found among the materials. The differences in flexural strength, fracture toughnes, wear and hardness may have been due to differences in chemistry or method of polymerization of the composites. Copyright © 2003 John Wiley & Sons, Ltd. [source]