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Wall Friction (wall + friction)
Selected AbstractsThe effect of mixer properties and fill level on granular flow in a bladed mixerAICHE JOURNAL, Issue 2 2010Brenda Remy Abstract The discrete element method was used to study the effect of mixer properties and fill level on the granular flow of monodisperse, cohesionless spheres in a bladed mixer. For fill levels just covering the span of the blades, a three-dimensional (3-D) recirculation zone develops in front of the blades, which promotes vertical and radial mixing. Increasing fill level reduces the size of the recirculation zone, decreases bed dilation and hinders particle diffusivities. However, above a critical fill level, the behavior of the particles within the span of the blade is found to be invariant of fill level. At low-fill levels, the pressure within the particle bed varies linearly with bed height and can be approximated by hydrostatics. At higher fill levels, a constant pressure region develops within the span of the blades due to the angled pitch of the blades. Cylinder wall friction is shown to significantly influence granular behavior in bladed mixers. At low-wall friction, the 3-D recirculation zone observed for high-wall friction conditions does not develop. High-wall friction leads to an increase in convective and diffusive particle mixing. Shear stresses are shown to be a function of wall friction. Blade position along the vertical axis is shown to influence flow patterns, granular temperature and stress. The effect of increasing the mixer diameter at a constant particle diameter was also studied. When the mixer diameter is larger than a critical size such that wall effects are minimized, the observed granular behavior follows simple scaling relations. Particle velocities and diffusivities scale linearly with mixer size and blade speed. Normal and shear stress profiles are found to scale linearly with the total weight of the particle bed. © 2009 American Institute of Chemical Engineers AIChE J, 2010 [source] The rheological properties of modified microcrystalline cellulose containing high levels of model drugsJOURNAL OF PHARMACEUTICAL SCIENCES, Issue 6 2009Paul E. Knight Abstract The rheological properties of different types of microcrystalline cellulose (MCC) mixed with model drugs and water have been evaluated to identify the influence of sodium carboxymethylcellulose (SCMC) added to the cellulose during preparation. A ram extruder was used as a capillary rheometer. The mixtures consisted of 20% spheronizing agent (standard grade MCC or modified types with 6% or 8% of low viscosity grade SCMC) and 80% of ascorbic acid, ibuprofen or lactose monohydrate. The introduction of SCMC changed all rheological parameters assessed. It produced more rigid systems, requiring more stress to induce and maintain flow. Degree of non-Newtonian flow, angle of convergence, extensional viscosity, yield and die land shear stress at zero velocity, and static wall friction were increased, but recoverable shear and compliance were decreased. The presence of SCMC did not remove the influence of the type of drug. The mixture of ibuprofen and standard MCC had the lowest values for shear stress as a function of the rate of shear, extensional viscosity, and angle of convergence, but the highest values for recoverable shear and compliance. The findings indicate that the system has insufficient rigidity to form pellets. © 2008 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 98:2160,2169, 2009 [source] Momentum Balance for Two-Phase Horizontal Pipe Flow Part 1: Friction FactorsASIA-PACIFIC JOURNAL OF CHEMICAL ENGINEERING, Issue 1-2 2004P. L. Spedding Estimations of gas wall, liquid wall and interfacial friction factors for two-phase horizontal co-current pipe flow are discussed critically after being checked against reliable data obtained under a wide range of conditions. The use of equivalent diameters and the Blasius relation were shown to be valid for estimation of the gas wall friction. Prediction of liquid wall and interfacial friction factors proved to be more difficult but estimation improved if consideration was given to the effects of liquid holdup and interfacial liquid shape. [source] |