Waveform Shocks (waveform + shock)

Distribution by Scientific Domains


Selected Abstracts


Open-Chest Epicardial "Surgical" Defibrillation:

PACING AND CLINICAL ELECTROPHYSIOLOGY, Issue 3 2003
Biphasic Versus Monophasic Waveform Shocks
ZHANG, Y., et al.: Open-Chest Epicardial "Surgical" Defibrillation: Biphasic Versus Monophasic Waveform Shocks. The aim of the study was to compare biphasic versus monophasic shocks for open-chest epicardial defibrillation. Transthoracic biphasic waveform shocks require less energy to terminate ventricular fibrillation compared to monophasic waveform shocks. However, if biphasic shocks are effective for open-chest epicardial ("surgical") defibrillation has not been established. Twenty-eight anesthetized adult swine (15,25 kg) underwent a midline sternotomy. Ventricular fibrillation was electrically induced. After 15 seconds of ventricular fibrillation, each pig in group 1(n = 16)randomly received damped sinusoidal monophasic epicardial shocks and truncated exponential biphasic epicardial shocks from large(44.2 cm2)paddle electrodes at eight energy levels(2,50 J). Pigs in group 2(n = 12)received monophasic and truncated exponential biphasic shocks from small(15.9 cm2)paddle electrodes. In group 1 (large paddle electrodes), the overall percent shock success rose from15 ± 9%at 2 J to97 ± 3%at 50 J. In this group there was no significant difference in percent of shock success between damped sinusoidal monophasic and biphasic waveform shocks. In group 2 (small paddle electrodes), biphasic shocks yielded a significantly higher percent of shock success than monophasic shocks at mid-energy levels from 7 to 20 J (allP < 0.01). With small surgical paddle electrodes, biphasic waveform shocks demonstrated a significantly higher percent of shock success rate compared to monophasic waveform shocks. With large paddle electrodes, the two waveforms were equally effective. (PACE 2003; 26:711,718) [source]


Biphasic versus Monophasic Cardioversion in Shock-Resistant Atrial Fibrillation:

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Issue 8 2003
A Randomized Clinical Trial
Introduction: Cardioversion of atrial fibrillation using monophasic transthoracic shocks occasionally is ineffective. Biphasic cardioversion requires less energy than monophasic cardioversion, but its efficacy in shock-resistant atrial fibrillation is unknown. Thus, we compared the efficacy of cardioversion using biphasic versus monophasic waveform shocks in patients with atrial fibrillation previously refractory to monophasic cardioversion. Methods and Results: Fifty-six patients with prior failed monophasic cardioversion were randomized to either a 360-J monophasic damped sinusoidal shock or biphasic truncated exponential shocks at 150 J, followed by 200 J and then 360 J, if necessary. If either waveform failed, patients were crossed over to the other waveform. The primary endpoint was defined as the proportion of patients achieving sinus rhythm following initial randomized therapy. Stepwise multivariate logistic regression examined independent predictors of shock success, including patient age, sex, left atrial diameter, body mass index, drug therapy, and waveform. Twenty-eight patients were randomized to the biphasic shocks and 28 to the monophasic shocks. Sinus rhythm was restored in 61% of patients with biphasic versus 18% with monophasic shocks (P = 0.001). Seventy-eight percent success was achieved in patients who crossed over to the biphasic shock after failing monophasic cardioversion, whereas only 33% were successfully cardioverted with a monophasic shock after crossover from biphasic shock (P = 0.02). Overall, 69% of patients who received a biphasic shock at any point in the protocol were cardioverted successfully, compared to 21% with the monophasic shock (P < 0.0001). The type of shock was the strongest predictor of shock success (P = 0.0001) in multivariate logistic regression. Conclusion: An ascending sequence of 150-, 200-, and 360-J transthoracic biphasic cardioversion shocks are successful more often than a single 360-J monophasic shock. Thus, biphasic shocks should be the recommended configuration of choice for all cardioversions. (J Cardiovasc Electrophysiol, Vol. 14, pp. 868-872, August 2003) [source]


Low Energy Biphasic Waveform Cardioversion of Atrial Arrhythmias in Pediatric Patients and Young Adults

PACING AND CLINICAL ELECTROPHYSIOLOGY, Issue 12 2006
LEONARDO LIBERMAN M.D.
Background: Low-dose biphasic waveform cardioversion has been used for the termination of atrial arrhythmias in adult patients. The energy required for termination of atrial arrhythmias in pediatric patients is not known. The objective of this study is to determine the minimum energy required for successful external cardioversion of atrial arrhythmias in pediatric patients using biphasic waveform current. Methods: Prospective study of all patients less than 24 years of age with and without congenital heart disease undergoing synchronized cardioversion for atrial arrhythmias. Patients were assigned to receive an initial biphasic energy shock of 0.2,0.5 J/kg and if unsuccessful in terminating the arrhythmia, subsequent sequential shocks of 1 and 2 J/kg would be administered until cardioversion was achieved. The end point of the cardioversion protocol was successful cardioversion or delivery of three shocks. Results: Between June 2005 and June 2006, 16 patients underwent biphasic cardioversion for atrial flutter or fibrillation. The mean age was 14.7 ± 6.4 years (range: 2 weeks to 24 years). The mean weight was 51 ± 21 kg (range: 3.8,82 kg). Seven patients had normal cardiac anatomy, three had a single ventricle (Fontan), two had a Senning operation; the remaining four patients had varied forms of congenital heart disease. The median length of time that the patients were in tachycardia was 12 hours (range: 5 minutes to 2 months). Using either transthoracic echocardiography (TTE) or transesophageal echocardiography (TEE), no thrombi were identified in any patient. All patients were successfully cardioverted with biphasic waveform energy. The successful energy shock was 0.35 ± 0.19 J/kg (range: 0.2,0.9 J/kg). All but one patient were successfully cardioverted with less than 0.5 J/kg. The transthoracic impedance range was between 41 and 144 ,; one patient had an impedance of 506 , (2-week-old infant with a weight of 3.8 kg). The mean current delivered was 5.4 ± 2.2 A (range: 1,11 A). Conclusion: Low-dose energy using biphasic waveform shocks can be used for successful termination of atrial arrhythmias in pediatric patients with and without congenital heart disease. [source]


Open-Chest Epicardial "Surgical" Defibrillation:

PACING AND CLINICAL ELECTROPHYSIOLOGY, Issue 3 2003
Biphasic Versus Monophasic Waveform Shocks
ZHANG, Y., et al.: Open-Chest Epicardial "Surgical" Defibrillation: Biphasic Versus Monophasic Waveform Shocks. The aim of the study was to compare biphasic versus monophasic shocks for open-chest epicardial defibrillation. Transthoracic biphasic waveform shocks require less energy to terminate ventricular fibrillation compared to monophasic waveform shocks. However, if biphasic shocks are effective for open-chest epicardial ("surgical") defibrillation has not been established. Twenty-eight anesthetized adult swine (15,25 kg) underwent a midline sternotomy. Ventricular fibrillation was electrically induced. After 15 seconds of ventricular fibrillation, each pig in group 1(n = 16)randomly received damped sinusoidal monophasic epicardial shocks and truncated exponential biphasic epicardial shocks from large(44.2 cm2)paddle electrodes at eight energy levels(2,50 J). Pigs in group 2(n = 12)received monophasic and truncated exponential biphasic shocks from small(15.9 cm2)paddle electrodes. In group 1 (large paddle electrodes), the overall percent shock success rose from15 ± 9%at 2 J to97 ± 3%at 50 J. In this group there was no significant difference in percent of shock success between damped sinusoidal monophasic and biphasic waveform shocks. In group 2 (small paddle electrodes), biphasic shocks yielded a significantly higher percent of shock success than monophasic shocks at mid-energy levels from 7 to 20 J (allP < 0.01). With small surgical paddle electrodes, biphasic waveform shocks demonstrated a significantly higher percent of shock success rate compared to monophasic waveform shocks. With large paddle electrodes, the two waveforms were equally effective. (PACE 2003; 26:711,718) [source]