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Ventricle Physiology (ventricle + physiology)

Distribution by Scientific Domains
Medical Sciences100%

Kinds of Ventricle Physiology

  • single ventricle physiology
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    Selected Abstracts

    Neurodevelopmental Outcomes in Infants after Surgery for Congenital Heart Disease: A Comparison of Single-Ventricle vs.

    CONGENITAL HEART DISEASE, Issue 2 2010
    Two-Ventricle Physiology
    ABSTRACT Introduction., The neurodevelopmental outcome of children with repaired congenital heart defect has risen in importance with improved survival. This study compares neurodevelopmental outcomes of children who had CHD with single ventricle physiology with those who had CHD with two-ventricle physiology. Patients and Methods., Participants included 112 infants discharged from the NICU between February 1999 to August 2006. The 12 infants who had a known genetic defect were excluded. Of the 100 infants 26 had single ventricle physiology and 74 had CHD with two-ventricle physiology. The children were seen in a follow-up clinic and growth parameters and standardized instruments were used to evaluate development. The referral rate to early intervention services was also compared. Results., The number of functional ventricles did not significantly differentiate growth parameters at 6,8 months of age. Early cognitive outcomes were relatively unimpaired in both the groups (single ventricle vs. two ventricle physiology). Early motor outcomes were worse in (p < 0.05) CHD with single ventricle physiology. The rate of referral for early intervention services was high in both groups compared to the average rate of referral in the state, but there was not a significant difference between the CHD groups. Conclusion., Significant differences noted on motor outcomes at the 6,8 month visit were no longer apparent in later visits. Referral to early intervention services is high in both the groups. These findings are important to those caring for infants with CHD because many of these patients may need referral for early intervention. [source]

    Techniques and Applications of Transcatheter Embolization Procedures in Pediatric Cardiology

    JOURNAL OF INTERVENTIONAL CARDIOLOGY, Issue 5 2003
    JAMES Y. SIM M.D.
    Transcatheter embolization of congenital or acquired superfluous vascular structure has become routine procedures performed by interventional pediatric cardiologists. Embolization procedure is often part of a collaborative effort with cardiac surgeons to palliate complex congenital heart defect, such as in embolizing aortopulmonary collateral arteries in patient with single ventricle physiology. In other cases, the procedure is the definitive treatment as in embolizing coronary artery fistula. Pediatric cardiologists performing embolization procedures should be familiar with available technologies as well as understand the underlying cardiac anatomy and pathophysiology. This article provides a comprehensive review of presently available embolization agents and technologies. Some of the technologies are used only by interventional radiologists but may be useful to pediatric cardiologists. Specific clinical applications in pediatric cardiology are also discussed with summary of current literature. With continue advancement in transcatheter technology and operator expertise, all unwanted vascular communication should be amenable to transcatheter embolization. (J Interven Cardiol 2003;16:425,448) [source]

    Children with corrected or palliated congenital heart disease on home mechanical ventilation,

    PEDIATRIC PULMONOLOGY, Issue 7 2010
    Jeffrey D. Edwards MD
    Abstract Infants and children with surgically corrected or palliated congenital heart disease (CHD) are at risk for chronic respiratory failure, necessitating home mechanical ventilation (HMV) via tracheostomy. However, very little data exists on this population or their outcomes. We conducted a retrospective chart review of all children with CHD enrolled in the Childrens Hospital Los Angeles HMV program between 1994 and 2009. Data were collected on type of heart lesion, surgeries performed, number of failed extubations, timing of tracheostomy, mortality, length of time on HMV, weaning status, associated co-morbidities, and Risk Adjusted classification for Congenital Heart Surgery (RACHS-1) category. Thirty-five children were identified; six with single ventricle anatomy, who received palliative procedures. Twenty-three (66%) patients are alive; 8 (23%) living patients have been weaned off HMV. Twelve (34%) patients are deceased. The incidence of mortality for single ventricle patients was 50%, and only one of the surviving children has received final palliation and weaned off HMV. Eight of nine patients (89%) with a RACHS score ,4 died, and none have been weaned off of HMV. The 5-year survival for all CHD HMV patients was 68%; 90% for patients with RACHS ,3; and 12% for patients with score ,4. Children with more complex lesions, as demonstrated by single ventricle physiology or greater RACHS scores, had higher mortality rates and less success weaning off HMV. This case series suggests that caregivers should give serious consideration to the type of heart defect as they advise families considering HMV in children with CHD. Pediatr Pulmonol. 2010; 45:645,649. © 2010 Wiley-Liss, Inc. [source]

    Design of a Protective Cage for an Intravascular Axial Flow Blood Pump to Mechanically Assist the Failing Fontan

    ARTIFICIAL ORGANS, Issue 8 2009
    Amy L. Throckmorton
    Abstract Currently, no long-term mechanical bridge-to-transplant or bridge-to-recovery therapeutic alternative exists for failing single ventricles. A blood pump that would augment pressure in the cavopulmonary circulation is needed, and would lead to a reduction in elevated systemic venous pressure, and improve cardiac output. Thus, we are developing a collapsible, percutaneously inserted, axial flow blood pump to support the cavopulmonary circulation in adult patients with a failing single ventricle physiology. This collapsible axial flow pump is designed for percutaneous positioning. The outer protective cage will be designed with radially arranged filaments as touchdown surfaces to protect the vessel wall from the rotating components. This study examined the geometric characteristics of the protective cage of filaments and the impeller through the development and numerical analysis of 13 models. A blood damage analysis was also performed on selected geometric models to assess the probability of blood trauma. All models demonstrated an acceptable hydraulic performance by delivering 2,6 L/min at a rotational speed of 6000,10 000 rpm and generating pressure rise of 5,20 mm Hg. Expected trends in the hydraulic performance of the pump models were found. This study represents the initial first design phase of the impeller and protective cage of filaments. Validation of these flow and performance predictions will be completed in the next round of experimental testing with blood bag evaluation. [source]