Various Outcomes (various + outcome)

Distribution by Scientific Domains


Selected Abstracts


The Sexual Debut of Girls in Early Adolescence: The Intersection of Race, Pubertal Timing, and Friendship Group Characteristics

JOURNAL OF RESEARCH ON ADOLESCENCE, Issue 3 2004
Shannon E. Cavanagh
Scholars who have studied the effects of early pubertal timing on girls' sexual debut contend that this association may result from the company they keep. Although this basic biosocial model of adolescent behavior has been applied to various outcomes with diverse samples of adolescent girls, less work has contextualized this microlevel developmental phenomenon within the larger macrolevel structures of race and ethnicity. Using a sample of White, African American, and Latina girls (N=1,299) drawn from the National Longitudinal Study of Adolescent Health, this study conducted within-group multivariate analyses and found important differences in the linkages that make up this biosocial model by race and ethnicity, with the linkages strongest for Whites, followed by Latina, and African American girls. These differences in association may reflect differences in the social construction of girlhood across race and ethnicity. [source]


The impact of volume on outcomes after oesophageal cancer surgery

ANZ JOURNAL OF SURGERY, Issue 9 2010
Ioannis Rouvelas
Abstract Oesophageal cancer is an aggressive disease with a poor prognosis. Oesophagectomy is an established, potentially curative treatment, for patients with resectable oesophageal cancer. The anatomical location of the oesophagus explains why this type of operation is one of the most demanding and traumatic surgical procedures undertaken in general surgery. Unfortunately, the risk for severe post-operative complications is high and the chance for cure remains low. It is, however, encouraging that the post-operative morbidity has been decreasing and the survival has been improving during recent years. Several factors might have contributed to this improvement, including the centralization of oesophageal cancer surgery to high volume centres. This review focuses on the impact of hospital and surgeon volume on various outcomes after oesophagectomy for oesophageal cancer. Most available research indicates that, as far as post-operative complications, early post-operative mortality and health economics after oesophagectomy are concerned, high surgery volume is to be recommended, while the few studies evaluating long-term survival and health-related quality of life adjusted for tumour stage found no evidence of a role for volume. In conclusion, the available literature supports the centralization of oesophagectomy for cancer to dedicated centres with a multidisciplinary approach and a good track record of valid clinical research. [source]


Leadership and Effectiveness in the Context of Gender: The Role of Leaders' Verbal Behaviour,

BRITISH JOURNAL OF MANAGEMENT, Issue 1 2008
Gisela Mohr
This field study focuses on verbal consideration, which is a leadership behaviour that expresses esteem for the follower and her or his work, knowledge and opinion. It was assumed that the relationship between verbal consideration and various outcomes is moderated by the leader's gender. One-hundred-and-forty leaders and 455 of their direct followers were surveyed in a one-wave questionnaire study in Germany. Male and female leaders showed the same degree of verbal consideration as rated by their followers. Verbal consideration is related to three out of four outcome variables for both sexes. One unexpected moderating effect of leaders' gender was found: followers of male leaders displaying verbal consideration report less ,irritation' (a state of exhaustion considered a threat to good task fulfilment). One explanation may be that male leaders get ,extra credit' for showing verbal consideration as it may be thought to entail special effort, whereas for female leaders it may be seen as normal and routine. This assumption should be examined in further studies in order to get more information about the different mechanisms by which female and male leaders reach the same quality of outcomes. [source]


Two-photon microscopy of host,pathogen interactions: acquiring a dynamic picture of infection in vivo

CELLULAR MICROBIOLOGY, Issue 4 2009
Vjollca Konjufca
Summary Two-photon (2P) microscopy has become increasingly popular among immunologists for analysing single-cell dynamics in tissues. Researchers are now taking 2P microscopy beyond the study of model antigen systems (e.g. ovalbumin immunization) and are applying the technique to examine infection in vivo. With the appropriate fluorescent probes, 2P imaging can provide high-resolution spatio-temporal information regarding cell behaviour, monitor cell functions and assess various outcomes of infection, such as host cell apoptosis or pathogen proliferation. Imaging of transgenic and knockout mice can be used to probe molecular mechanisms governing the host response to infection. From the microbe side, imaging genetically engineered mutant strains of a pathogen can test the roles of specific virulence factors in pathogenesis. Here, we discuss recent work that has applied 2P microscopy to study models of infection and highlight the tremendous potential that this approach has for investigating host,pathogen interactions. [source]


Low socioeconomic status as a risk factor for asthma, rhinitis and sensitization at 4 years in a birth cohort

CLINICAL & EXPERIMENTAL ALLERGY, Issue 5 2005
C. Almqvist
Summary Background The relation between socioeconomic status and allergic diseases in childhood is controversial. Some studies have proposed childhood asthma to be more common in families with low socioeconomic status, while sensitization to airborne allergens seems to be more frequent in individuals with higher socioeconomic status in childhood. Objective To assess the relation between socioeconomic status and asthma, rhinitis and sensitization in an unselected prospective birth cohort. Methods Four thousand and eighty-nine families with children born 1994,1996 in predefined areas of Stockholm answered questionnaires on environmental factors, socioeconomic status (parental occupation), and symptoms of allergic disease at birth, 1, 2 and 4 years of age. Blood samples taken at 4 years from 2614 children were analysed for specific IgE to common airborne and food allergens. Odds ratios (OR) and 95% confidence intervals (CI) for various outcomes in relation to socioeconomic status were estimated with a multiple logistic regression model, adjusting for potential confounders such as heredity for allergic diseases, maternal smoking, short duration of breastfeeding and house construction. Results There was a decreasing risk of asthma and rhinitis with increasing socioeconomic status. The OR for asthma was 0.33 (95% CI 0.17,0.66) and for rhinitis 0.50 (0.32,0.79) comparing the highest and the lowest socioeconomic groups, with a tendency to stronger effects in those with heredity for allergic disease. The risk of sensitization to food allergens also decreased with increasing socioeconomic status; OR 0.65 (0.41,1.02) in the highest socioeconomic group (Ptrend=0.03), which was not clearly seen for airborne allergens. Conclusion Asthma, rhinitis and sensitization is more common in lower than in higher socioeconomic groups after adjustment for traditional risk factors. This may be related to additional uncontrolled differences in life style and environmental exposures between the groups, and calls for further studies. [source]