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Unusual Reaction (unusual + reaction)
Selected AbstractsMetallic Taste: An Unusual Reaction to Botulinum Toxin ADERMATOLOGIC SURGERY, Issue 5 2003Christian Murray MD BACKGROUND Botulinum neurotoxin formulations are safe and effective agents for the treatment of facial rhytides. OBJECTIVES A patient is described who complained of metallic taste after each treatment with botulinum toxin A (BTX-A). RESULTS The sensation of metallic taste diminished after successive treatments with BTX-A, despite adequate dosing for cosmetic purposes. CONCLUSION Metallic taste is associated with the use of numerous medications; however, the pathogenesis remains unclear. Alteration in zinc metabolism, which may occur with BTX-A administration, has been suggested as a possible mechanism. Although this is the first known report of dysgeusia after BTX-A, physicians and patients may be reassured that the taste alteration was self-limited and was not significantly problematic for the patient in our case. [source] An Unusual Reaction of (,-Dimethylaminoethoxy)triethyltin with Phenyltin Trichloride.EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 21 2006Aryl; X, Symmetrical Dimers [R2SnXY], The First X-ray Structural Evidence of the Existence of Complexes R2SnXY·R2SnXY (R = Alkyl, Y = Hal, Y) Both as Unsymmetrical Adducts [R2SnX2·R2SnY2] Abstract The substituent exchange reaction of PhSnCl3 with [Et3Sn(OCH2CH2NMe2)] gives rise unexpectedly to the unsymmetrical adduct [Ph2SnCl2·Ph2Sn(OCH2CH2NMe2)2] (2). It has been unambiguously proved for the first time that compounds of the RSnX3 type are able to undergo the hydrocarbon substituent redistribution reaction. The analogous tin complexes [Et2SnCl2·Et2Sn(OMe)2] (5) and [Bu2Sn(OAc)2·Bu2Sn(OMe)2] (6), which have ligands other than ,-dimethylaminoethoxy and could be considered as "organotin analogs of Grignard reagents" have symmetrical dimeric structures, i.e., can be formulated as [Bu2Sn(OMe)(OAc)]2 and [Et2Sn(OMe)Cl]2, respectively. Both types of structures, viz., unsymmetrical adduct (2) and symmetrical dimer (5, 6), have been characterized by X-ray diffraction analysis. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006) [source] ChemInform Abstract: Unusual Reaction of 7-Methyl-1,3,7-triazapyrenium Salts with Aqueous K3[Fe(CN)6] Solution.CHEMINFORM, Issue 6 2010O. P. Demidov Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Unusual Reaction of Chloroacetyl Chloride with 1,2-Dichloroethene.CHEMINFORM, Issue 26 2009Properties of 2-Chlorovinyl Dichloromethyl Ketone., Synthesis Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Unusual Reaction of 5-Benzoyl-3-ethoxycarbonyl-6-methylthio-1-R-1,2-dihydropyridin-2-ones with 1,3-DiaminopropaneCHEMINFORM, Issue 21 2009V. N. Britsun Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Unusual Reaction of Chloroacetyl Chloride with 1,2-Dichloroethylene.CHEMINFORM, Issue 51 20084-Trichlorobut-3-en-2-one., Synthesis of Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Unusual Reaction of Ethyl 2-Cyano-3,3-bis(methylsulfanyl)acrylate with Cyanothioacetamide.CHEMINFORM, Issue 51 2006V. D. Dyachenko Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] An Unusual Reaction of (2-Oxo-1,2-dihydro-3H-indol-3-ylidene)acetic Acid Esters with Hydrazine.CHEMINFORM, Issue 11 2006V. O. Kozminykh Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Unusual Reaction of ,-Hydroxy ,-Diazo Carbonyl Compounds with TsNHN=CHCOCl/Et3N.CHEMINFORM, Issue 37 2004Weifeng Shi Abstract For Abstract see ChemInform Abstract in Full Text. [source] Unusual Reaction of Chloramine-T with Araldoximes.CHEMINFORM, Issue 26 2003V. Padmavathi Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: Unusual Reaction of Condensed 2,3-Dihydro-2,3-pyrrolediones (I) with o-Phenylenediamine.CHEMINFORM, Issue 30 2001I. V. Mashevskaya Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Unusual Reactions Between Aromatic Carbon Supernucleophiles and 1,2-Diazabuta-1,3-dienes: Useful Routes to New Pyrazolone and Cinnoline Derivatives.CHEMINFORM, Issue 52 2008Luciano Forlani Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Pseudoepitheliomatous hyperplasia , an unusual reaction following tattoo: report of a case and review of the literatureINTERNATIONAL JOURNAL OF DERMATOLOGY, Issue 7 2007Wei Cui MD A 59-year-old woman presented with an itchy and uncomfortable raised lesion at a tattoo site (Fig. 1) on the lateral aspect of the left leg, just above the ankle. The tattoo had been placed 2 years before her presentation and the tattoo site was sun exposed. Immediately after she had the tattoo, she noticed redness of the skin. After a week, a pruritic and red scaly nodule developed that continued to gradually enlarge until her presentation. The patient had tried topical vitamin A and D ointment with no relief. The patient also had tattoos on the arms without any noticeable skin changes. The patient reported that the tattoo procedure on her leg was more painful than that on her arms, and was performed by a different (and perhaps inexperienced) tattoo artist. The original tattoo contained red, green, and yellow pigments. Figure 1. Raised nodular lesion with irregular margins A diagnosis of tattoo granuloma was considered; squamous cell carcinoma and fungal infection were included in the differential diagnosis. A punch biopsy was performed, followed by complete surgical excision of the lesion with a split-thickness skin graft from the right thigh. The skin excision specimen showed a 3 × 2.5-cm granular and pitted pink lesion with well-demarcated, somewhat irregular borders. The lesion was raised 0.5 cm above the skin surface. The lesion was present in the center of the original tattoo. Portions of the original tattoo with green and blue,green pigmentation were visible on either side of the lesion. No satellite lesions were identified. Microscopically, the raised lesion demonstrated striking pseudoepitheliomatous hyperplasia, with irregular acanthosis of the epidermis and follicular infundibula, hyperkeratosis, and parakeratosis (Fig. 2). Follicular plugging was present with keratin-filled cystic spaces. There was a brisk mononuclear inflammatory infiltrate in the dermis, composed primarily of lymphocytes, with admixed plasma cells and histiocytes. Giant cells were occasionally identified. Dermal pigment deposition was noted both within the lesion and in the surrounding skin, corresponding to the original tattoo. Variable dermal fibrosis was noted, with thick collagen bundles in some areas. There was no evidence of epidermal keratinocytic atypia, dyskeratosis, or increased suprabasal mitotic activity. Special stains (periodic acid,Schiff and acid-fast) for microorganisms were negative. Figure 2. (a) Raised lesion with marked pseudoepitheliomatous hyperplasia and follicular plugging (hematoxylin and eosin; magnification, ×2.5). (b) Irregularly elongated and thickened rete pegs with blunt ends associated with dermal chronic inflammation (hematoxylin and eosin; magnification, ×5). (c) Follicular dilation and plugging with keratin-filled cystic spaces (hematoxylin and eosin; magnification, ×5). (d) Dermal pigment and fibrosis (hematoxylin and eosin; magnification, ×10) [source] Persistent urticaria characterized by recurrent lasting urticarial erythema with histological features of prominent perivascular eosinophilic infiltrationCLINICAL & EXPERIMENTAL DERMATOLOGY, Issue 5 2009H. Amano Summary We report a 29-year-old woman with a 15-year history of recurrent pruritic urticarial erythemas. The individual lesions lasted for > 24 h, and antihistaminic agents were not effective. Histological examination of a skin biopsy revealed interstitial oedema of the dermis and perivascular infiltration of numerous eosinophils without vasculitis. No internal organ involvement or peripheral blood eosinophilia was present. A diagnosis of persistent urticaria was made and the patient was successfully treated with oral corticosteroid therapy. Persistent urticaria has been described as an unusual reaction that lasts longer than typical urticaria. It is effectively treated with corticosteroids, but not with antihistaminic agents. In order to choose the most effective treatment, persistent urticaria should be recognized as a different clinical condition from typical urticaria. [source] Bioactive taxoids from the Japanese yew Taxus cuspidataMEDICINAL RESEARCH REVIEWS, Issue 3 2002Jun'ichi Kobayashi Abstract A series of new taxoids, named taxuspines A,H and J,Z (1,25) and taxezopidines A,H and J,L (26,36), have been isolated together with 37 known taxoids (37,73) including paclitaxel (53) from the Japanese yew, Taxus cuspidata Sieb. et Zucc. (Taxaceae). These new taxoids possess various skeletons containing 5/7/6, 6/10/6, 6/5/5/6, 6/8/6, or 6/12-membered ring systems. Among the new taxoids, some non-taxol-type compounds remarkably reduced CaCl2 -induced depolymerization of microtubules, or increased cellular accumulation of vincristine in multidrug-resistant tumor cells as potent as verapamil. On the other hand, chemical derivatization of taxinine (37), one of major taxoids obtained from this yew, led to the discovery of unusual reactions of taxinine derivatives. Here we describe our recent results on the isolation, structure elucidation, and bioactivity of these new and known taxoids and the formation of unexpected products of the unusual reactions of taxinine. © 2002 Wiley Periodicals, Inc. Med Res Rev, 22, No. 3, 305,328, 2002; Published online in wiley InterScience (www.interscience.wiley.com). DOI 10.1002/med.10005 [source] | |||||||||||||