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Ultimate Load (ultimate + load)
Selected AbstractsAn unconditionally convergent algorithm for the evaluation of the ultimate limit state of RC sections subject to axial force and biaxial bendingINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN ENGINEERING, Issue 8 2007G. Alfano Abstract We present a numerical procedure, based upon a tangent approach, for evaluating the ultimate limit state (ULS) of reinforced concrete (RC) sections subject to axial force and biaxial bending. The RC sections are assumed to be of arbitrary polygonal shape and degree of connection; furthermore, it is possible to keep fixed a given amount of the total load and to find the ULS associated only with the remaining part which can be increased by means of a load multiplier. The solution procedure adopts two nested iterative schemes which, in turn, update the current value of the tentative ultimate load and the associated strain parameters. In this second scheme an effective integration procedure is used for evaluating in closed form, as explicit functions of the position vectors of the vertices of the section, the domain integrals appearing in the definition of the tangent matrix and of the stress resultants. Under mild hypotheses, which are practically satisfied for all cases of engineering interest, the existence and uniqueness of the ULS load multiplier is ensured and the global convergence of the proposed solution algorithm to such value is proved. An extensive set of numerical tests, carried out for rectangular, L-shaped and multicell sections shows the effectiveness of the proposed solution procedure. Copyright © 2007 John Wiley & Sons, Ltd. [source] Effects of Liver-Derived Insulin-Like Growth Factor I on Bone Metabolism in Mice,JOURNAL OF BONE AND MINERAL RESEARCH, Issue 11 2002Klara Sjögren Abstract Insulin-like growth factor (IGF) I is an important regulator of both skeletal growth and adult bone metabolism. To better understand the relative importance of systemic IGF-I versus locally expressed IGF-I we have developed a transgenic mouse model with inducible specific IGF-I gene inactivation in the liver (LI-IGF-I,/,). These mice are growing normally up to 12 weeks of age but have a disturbed carbohydrate and lipid metabolism. In this study, the long-term effects of liver-specific IGF-I inactivation on skeletal growth and adult bone metabolism were investigated. The adult (week 8,55) axial skeletal growth was decreased by 24% in the LI-IGF-I,/, mice whereas no major reduction of the adult appendicular skeletal growth was seen. The cortical cross-sectional bone area, as measured in the middiaphyseal region of the long bones, was decreased in old LI-IGF-I,/, mice. This reduction in the amount of cortical bone was caused mainly by decreased periosteal circumference and was associated with a weaker bone determined by a decrease in ultimate load. In contrast, the amount of trabecular bone was not decreased in the LI-IGF-I,/, mice. DNA microarray analysis of 30-week-old LI-IGF-I,/, and control mice indicated that only four genes were regulated in bone whereas ,40 genes were regulated in the liver, supporting the hypothesis that liver-derived IGF-I is of minor importance for adult bone metabolism. In summary, liver-derived IGF-I exerts a small but significant effect on cortical periosteal bone growth and on adult axial skeletal growth while it is not required for the maintenance of the trabecular bone in adult mice. [source] Long-Term Effect of Incadronate Disodium (YM-175) on Fracture Healing of Femoral Shaft in Growing RatsJOURNAL OF BONE AND MINERAL RESEARCH, Issue 3 2001Chaoyang Li Abstract The aim of this study was to investigate the long-term effect of incadronate on fracture healing of the femoral shaft in rats. Female Sprague-Dawley 8-week-old rats were injected subcutaneously (sc) with either vehicle (V group) or two doses of incadronate (10 ,g/kg and 100 ,g/kg) three times a week for 2 weeks. Right femoral diaphysis was then fractured and fixed with intramedullary stainless wire. Just after fracture, incadronate treatment was stopped in pretreatment groups (P groups: P-10 and P-100) or continued in continuous treatment groups (C groups: C-10 and C-100). All rats were killed at 25 weeks or 49 weeks after surgery. Fractured femur was evaluated radiologically and mechanically and then stained in Villanueva bone stain and embedded in methyl methacrylate. Undecalcified cross-sections from the fracture area were evaluated microradiologically and histomorphometrically. Radiographic observation showed that the fracture line disappeared in all groups. Cross-sectional area in the C-100 group was the biggest among all groups and in the C-10 group was larger than that in the V group at 25 weeks. Histological and histomorphometric observations showed that the process of fracture healing was delayed under continuous treatment with incadronate as evidenced by the delay of both lamellar cortical shell formation and resolution of original cortex in C groups. Percent linear labeling perimeter, mineral apposition rate (MAR), and bone formation rate (BFR) in C groups significantly decreased compared with the other groups, indicating that the callus remodeling was suppressed under continuous treatment, especially with a high dose. Mechanical study showed that the stiffness and ultimate load of the fractured femur in the C 100 group were the highest among all groups at both 25 weeks and 49 weeks. In conclusion, this study showed that long-term continuous treatment with incadronate delayed the process of fracture healing of femur in rats, especially under high dose but it did not impair the recovery of mechanical integrity of the fracture. [source] Use of a bioscaffold to improve healing of a patellar tendon defect after graft harvest for ACL reconstruction: A study in rabbitsJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 2 2008Sinan Karaoglu Abstract Following harvest of a bone-patellar tendon-bone (BPTB) autograft, the central third of the patellar tendon (PT) does not heal well. The healing tissues also form adhesions to the fat pad and can cause abnormal patellofemoral joint motion. The hypotheses were that a bioscaffold could enhance patellar tendon healing through contact guidance and chemotaxis, and the scaffold could serve as a barrier to decrease adhesion formation between the neo-PT and infrapatellar fat pad. In 20 New Zealand White rabbits, a central-third PT defect was created. One strip of porcine small intestinal submucosa (SIS) was attached to both the anterior and posterior sides of the PT defect of the SIS-treated group (n,=,10). For comparison, a central defect was left nontreated (n,=,10). At 12 weeks, histomorphology was examined using Masson's trichrome staining. The cross-sectional area (CSA) was determined with a laser micrometer, and the central BPTB complexes were tested in uniaxial tension. SIS-treated samples showed a greater amount of healing tissue with denser and well-oriented collagen fibers and more spindle-shaped cells. There was no noticeable adhesion formation in the SIS-treated group. For the nontreated group, there were significantly more and diffuse adhesive formations. The SIS-treated group also had a 68% increase in neo-PT CSA, 98% higher stiffness, and 113% higher ultimate load than that in the nontreated group. SIS treatment increased the quantity of healing tissue, improved the histological appearance and biomechanical properties of the neo-PT, and prevented adhesion formation between the PT and fat pad. © 2007 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 26:255,263, 2008 [source] Effect of cortical thickness and cancellous bone density on the holding strength of internal fixator screwsJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 6 2004J. Seebeck Abstract Internal fixators are a new class of implants designed to preserve the periosteal blood supply of the bone. In contrast to conventional plate fixation in which the screws have spherical heads and are loaded mainly by axial pullout forces, screws in internal fixators are "locked" within the plate and therefore subjected to axial as well as bending loads. In this study the ultimate loads of screws of a commercially available internal fixator system were tested in a pullout (n = 72) and cantilever bending mode (n = 72) in metaphyseal and diaphyseal regions of four pairs of human tibiae with different bone qualities. Cortical thickness and cancellous bone density were determined at the screw insertion sites. Stepwise multiple linear regression revealed that cortical thickness and cancellous density can explain 93% and 98% of the variance of the ultimate load of the screws in an axial pullout and cantilever bending mode. Screws in internal fixators are better suited to transmit shear forces and thereby make better use of the strength potential of bone than screws used in conventional plate fixation: this is especially advantageous when bone strength is reduced, e.g. due to osteoporosis. © 2004 Orthopaedic Research Society. Published by Elsevier Ltd. All rights reserved. [source] Mechanical properties of the scapholunate ligament correlate with bone mineral density measurements of the handJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 4 2004James D. Johnston Abstract The mechanical properties of the scapholunate ligament have been previously examined in small sample sizes, with ultimate load and occasionally stiffness reported. The present study examined 16 scapholunate ligaments in uniaxial extension at two rates and determined stiffness, ultimate load, and stress relaxation properties. Mean stiffness values of 66.4 ± 28.6 N/mm at an elongation rate of 50 mm/min and 94.5 ± 44.4 N/mm at an elongation rate of 100 mm/min were found. Relaxation behavior, determined by the percent load remaining after 100 s, was found to be 68.1 ± 12%. Mean ligament ultimate loads were 357 ± 110 N (n = 8). In eight specimens, failure occurred in bone. Positive correlations were observed between bone mineral density of the hand and ligament stiffness, ligament ultimate load, and bone ultimate load. No correlation was observed between bone mineral density and ligament load relaxation behavior. The results provide a comprehensive understanding of scapholunate ligament biomechanics and demonstrate a relationship between bone and ligament properties. © 2004 Orthopaedic Research Society. Published by Elsevier Ltd. All rights reserved. [source] Biomechanical consequences of an isolated overload on the human vertebral bodyJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 5 2000David L. Kopperdahl The biomechanical consequences of an isolated overload to the vertebral body may play a role in the etiology of vertebral fracture. In this context, we quantified residual strains and reductions in stiffness and ultimate load when vertebral bodies were loaded to various levels beyond the elastic regimen and related these properties to the externally applied strain and bone density. Twenty-three vertebral bodies (T11-L4, from 23 cadavers aged 20,90 years) were loaded once in compression to a randomized nominal strain level between 0.37 and 4.5%, unloaded, and then reloaded to 10% strain. Residual strains of up to 1.36% developed on unloading and depended on the applied strain (r2 = 0.85) but not on density (p = 0.25). Percentage reductions in stiffness and ultimate load of up to 83.7 and 52.5%, respectively, depended on both applied strain (r2 = 0.90 and r2 = 0.32, respectively) and density (r2 = 0.23 and r2 = 0.22, respectively). Development of residual strains is indicative of permanent deformations, whereas percentage reductions in stiffness are direct measures of effective mechanical damage. These results therefore demonstrate that substantial mechanical damage,which is not visible from radiographs,can develop in the vertebral body after isolated overloads, as well as subtle but significant permanent deformations. This behavior is similar to that observed previously for cylindrical cores of trabecular bone. Taken together, these findings indicate that the damage behavior of the lumbar and lower thoracic vertebral body is dominated by the trabecular bone and may be an important factor in the etiology of vertebral fracture. [source] Melatonin effect on bone metabolism in rats treated with methylprednisoloneJOURNAL OF PINEAL RESEARCH, Issue 4 2006Marta G. Ladizesky Abstract:, The present study was undertaken to examine the effect of melatonin (25 ,g/mL of drinking water, about 500 ,g/day) on a 10-wk long treatment of male rats with methylprednisolone (5 mg/kg s.c., 5 days/wk). Bone densitometry and mechanical properties, calcemia, phosphatemia and serum bone alkaline phosphatase activity and C-telopeptide fragments of collagen type I (CTX) were measured. Both melatonin and methylprednisolone decreased significantly body weight (BW) and the combination of both treatments resulted in the lowest BW values found. Consequently, all results were analyzed with BW as a covariate. Densitometrically, methylprednisolone augmented bone mineral content (BMC), bone area (BA) and bone mineral density (BMD) in the entire skeleton, BMC in cortical bone, and BMC and BMD in trabecular bone. Melatonin increased BMC and BA in whole skeleton and BMC and BMD in trabecular bone. For BMC and BA of whole skeleton, BMC of cortical bone, and BMC and BMD of trabecular bone, the combination of glucocorticoids and melatonin resulted in the highest values observed. Femoral weight of rats receiving methylprednisolone or melatonin increased significantly and both treatments summated to achieve the greatest effect. In femoral biomechanical testing, methylprednisolone augmented ultimate load and work to failure significantly. Rats receiving the combined treatment of methylprednisolone and melatonin showed the highest values of work to failure. The circulating levels of CTX, an index of bone resorption, decreased after methylprednisolone or melatonin, both treatments summating to achieve the lowest CTX values found. Serum calcium increased after methylprednisolone and serum phosphorus decreased after treatment with methylprednisolone or melatonin while serum bone alkaline phosphatase levels remained unchanged. The results are compatible with the view that low doses of methylprednisolone or melatonin decrease bone resorption and have a bone-protecting effect. [source] Nonlinear FEM Simulation of Air Cushion Vehicle (ACV) Skirt Joint Under Tension LoadingNAVAL ENGINEERS JOURNAL, Issue 2 2009JIA ZHOU The mechanical properties of an air cushion vehicle (ACV) skirt cloth, which is a nonlinear rubber-coated fabric, are tested on a Series IX 4465 electron tension machine manufactured by Instron Company. Compared with the Mooney,Rivlin and Ogden form, the second-order Mooney,Rivlin form agrees with the model test result better. The ultimate bearing capacity of an ACV skirt joint structure is tested on a mechanical tension machine and the ultimate load is recorded manually. Then, considering the contact effect of each assembly and the large-displacement of skirt elements, a nonlinear finite element method (FEM)-based simulation process of an ACV skirt joint structure under tension loading is presented. The simulation process comprises three steps: assembly of parts, bolts' tightening, and tensioning the skirt cloth. Under these loadings, the stress distribution and deformation of the skirt cloth, and the cloth broken locations and directions are obtained. These results agree well with the test results. As for the ultimate bearing capacity of the skirt joint, the simulation result is slightly smaller than the test result. Thus, this FEM-based simulation method is proven to be reliable and relatively conservative. [source] Effect of cortical thickness and cancellous bone density on the holding strength of internal fixator screwsJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 6 2004J. Seebeck Abstract Internal fixators are a new class of implants designed to preserve the periosteal blood supply of the bone. In contrast to conventional plate fixation in which the screws have spherical heads and are loaded mainly by axial pullout forces, screws in internal fixators are "locked" within the plate and therefore subjected to axial as well as bending loads. In this study the ultimate loads of screws of a commercially available internal fixator system were tested in a pullout (n = 72) and cantilever bending mode (n = 72) in metaphyseal and diaphyseal regions of four pairs of human tibiae with different bone qualities. Cortical thickness and cancellous bone density were determined at the screw insertion sites. Stepwise multiple linear regression revealed that cortical thickness and cancellous density can explain 93% and 98% of the variance of the ultimate load of the screws in an axial pullout and cantilever bending mode. Screws in internal fixators are better suited to transmit shear forces and thereby make better use of the strength potential of bone than screws used in conventional plate fixation: this is especially advantageous when bone strength is reduced, e.g. due to osteoporosis. © 2004 Orthopaedic Research Society. Published by Elsevier Ltd. All rights reserved. [source] Mechanical properties of the scapholunate ligament correlate with bone mineral density measurements of the handJOURNAL OF ORTHOPAEDIC RESEARCH, Issue 4 2004James D. Johnston Abstract The mechanical properties of the scapholunate ligament have been previously examined in small sample sizes, with ultimate load and occasionally stiffness reported. The present study examined 16 scapholunate ligaments in uniaxial extension at two rates and determined stiffness, ultimate load, and stress relaxation properties. Mean stiffness values of 66.4 ± 28.6 N/mm at an elongation rate of 50 mm/min and 94.5 ± 44.4 N/mm at an elongation rate of 100 mm/min were found. Relaxation behavior, determined by the percent load remaining after 100 s, was found to be 68.1 ± 12%. Mean ligament ultimate loads were 357 ± 110 N (n = 8). In eight specimens, failure occurred in bone. Positive correlations were observed between bone mineral density of the hand and ligament stiffness, ligament ultimate load, and bone ultimate load. No correlation was observed between bone mineral density and ligament load relaxation behavior. The results provide a comprehensive understanding of scapholunate ligament biomechanics and demonstrate a relationship between bone and ligament properties. © 2004 Orthopaedic Research Society. Published by Elsevier Ltd. All rights reserved. [source] Das Druckgurtmodell für StahlbetonbauteileBETON- UND STAHLBETONBAU, Issue 8 2009Der nachfolgende Beitrag erscheint aus Anlass des 60. Berechnungs- und Bemessungsverfahren; Versuche Abstract In den vergangenen Jahren wurden verschiedene auf die Bemessung von Stahl- und Spannbetonbauteilen ausgerichtete theoretische Modelle entwickelt. Heute stehen das Zuggurtmodell, das Modell der gerissenen (Steg-)Scheibe und das Druckgurtmodell zur Verfügung, auf deren Grundlage Verformungsverhalten und Tragwiderstände umfassend beurteilt werden können. Auf das Druckgurtmodell wird im vorliegenden Beitrag detailliert eingegangen. Es berücksichtigt die Festigkeits- und Duktilitätssteigerung durch eine Umschnürungsbewehrung sowie die bruchmechanisch begründete Entfestigung des Betons und die damit einhergehende Verformungslokalisierung. Auf der Grundlage neuerer Versuchsergebnisse können für die komplexen Interdependenzen zwischen diesen Effekten plausible Beziehungen angegeben werden. Die mithilfe des Druckgurtmodells gewonnenen Erkenntnisse sind für die Baupraxis von Bedeutung: Das Verhalten von auf Druck beanspruchten Bauteilen (z. B. Druckplatten von Brückenquerschnitten, Stützen) lässt sich zuverlässig erfassen; darüber hinaus ergeben sich wichtige Hinweise für die konstruktive Durchbildung. Compression Chord Model for Structural Concrete In recent years, several theoretical models have been developed with the scope on the design of reinforced and prestressed concrete structures. Today, the tension chord model, the cracked membrane model and the compression chord model are available, with which the deformation behaviour as well as ultimate loads can be determined. In the present contribution the compression chord model is discussed in detail. The model takes the increase of strength and ductility due to a confining reinforcement into account and considers the softening as well as the localisation of deformations accompanying the fracture of concrete. On the basis of new test results plausible relations for the complex interdependencies between these effects are found. The results of the compression chord model are relevant for practical applications: The behaviour of compressed members (e.g. in bridge girders or columns) can be assessed reliably; moreover, hints for the detailing of reinforcement can be deduced. [source] | |||||||||||||