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Tricyclic Derivatives (tricyclic + derivative)
Selected AbstractsChemInform Abstract: Design and Synthesis of Tricyclic Derivatives as High Density Lipoprotein Cholesterol Enhancers.CHEMINFORM, Issue 18 2001Hassan Elokdah Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] 1H and 13C NMR spectral data for a tricyclic derivative of a Diels,Alder adductMAGNETIC RESONANCE IN CHEMISTRY, Issue 1 2006Susimaire Pedersoli Abstract A complete NMR analysis with full assignment for 1H and 13C NMR spectral data for 5-(acetyloxy)-3-hydroxy-9,10-dimethoxy-6-oxo-11-oxatricyclo[6.2.1.02,7]undec-2-yl acetate (8) is described. This compound was prepared by rapid hydrogenation of the unstable Diels,Alder adduct obtained from the reaction between 3,4-dimethoxyfuran (4) and 2,5-diacetoxy-1,4-benzoquinone (5). Full homonuclear hydrogen coupling constants measurements and molecular mechanics calculations were performed for the determination of the relative stereochemistry. Copyright © 2005 John Wiley & Sons, Ltd. [source] Synthesis of tricyclic pyrido[2,3-b][1,4]-thiazines via nucleophilic substitution of activated precursorsJOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 5 2003Manuela Weber Pyrido-anellated compounds analogous to tricyclic 1,4-benzothiazine derivatives were synthesized. Thus, under mild reaction conditiones substitution of thiolactim 3 with different N -nucleophiles yielded the precursors for compounds, which were cyclized in a further step to the corresponding tricyclic derivatives. [source] A convenient synthesis of 5- and 8-nitroquinazoline-2,4-dione derivativesJOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 2 2002D. Aziane 3-Nitrophthalic acid 1 was converted selectively to the two regioisomeric monoesters 2 and 3, which were subsequently transformed via Curtius rearrangement to the corresponding 5- and 8-nitroquinazoline-2,4-diones 4 and 5, respectively. The reduction of the nitro group produced 5- and 8-aminoquinazoline-2,4-diones 6 and 7, respectively, in good yields. The condensation of compounds 7b and 7c with carbon disulfide in pyridine afforded tricyclic derivatives 9, which are analogues of the HIV-1 reverse transcriptase inhibitor 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1- jk][1,4]benzodiazepin-2(1H)-one(TIBO). [source] | ||||||||||