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Triazole Compounds (triazole + compound)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

Efficient Synthesis of 5-Fluoroalkylated 1H-1,2,3-Triazoles and Application of the Bromodifluoromethylated Triazole to Prepare New gem-Difluorinated Triazole Compounds.

CHEMINFORM, Issue 19 2003
Weimin Peng
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

Preparation, characterization and biological activities of novel ferrocenyl-substituted azaheterocycle compounds

APPLIED ORGANOMETALLIC CHEMISTRY, Issue 3 2003
Jian-Xin Fang
Abstract ,-Haloacetylferrocene and ,-triazolylacetylferrocene have been prepared from acetylferrocene and they have proved to be useful building blocks for the synthesis of ferrocenyl propenone. Two new types of ferrocenyl vinyl triazole compound, (Z,E)-ferrocenyl-[1-(1,2,4-triazol-1-yl)-2-phenyl]-vinyl-ones, have been synthesized and their structures characterized by crystal X-ray diffraction analysis. It has been shown for the first time that ferrocene, as an organometallic compound, has been introduced into bioactive triazole compounds in search of potent bioactive substances. Their biological activities are also discussed. Copyright © 2003 John Wiley & Sons, Ltd. [source]

Rapid Diversity-Oriented Synthesis in Microtiter Plates for In Situ Screening of HIV Protease Inhibitors

CHEMBIOCHEM, Issue 11 2003
Ashraf Brik Dr.
Click and go: By using click chemistry based on a new triazole forming reaction condition (see scheme), over 100 triazole compounds generated in microtiter plates from a core structure were screened for HIV protease inhibition in situ without product isolation. Potent inhibitors, active at nanomolar concentrations, against the wild type and drug resistant mutants were identified. [source]