Treatment Panel III (treatment + panel_iii)

Distribution by Scientific Domains

Terms modified by Treatment Panel III

  • treatment panel iii criterioN

  • Selected Abstracts

    The prevalence of metabolic syndrome in Japanese renal transplant recipients

    NEPHROLOGY, Issue 4 2007
    SUMMARY: Background: The prevalence of metabolic syndrome (MS) after renal transplantation has yet to be elucidated. In the present study, we investigated the prevalence of MS in Japanese renal transplant recipients. Methods: A cross-sectional study was conducted to determine the prevalence of MS in 101 renal transplant recipients at Osaka City University Hospital. The prevalence of MS was determined using the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATPIII) criteria (modified and original) and the International Diabetes Federation (IDF) criteria. Results: Using the modified (Japanese) NCEP criteria, a total of 24 out of 101 patients (23.8%) had MS including 21 out of 64 male patients (32.8%) and three out of 37 female patients (8.1%). Using the modified (Asian) NCEP criteria, MS was diagnosed in 23 patients (22.8%); 19 male (29.7%) and four female (10.8%). Using the original NCEP criteria, MS was diagnosed in 15 patients (14.9%); 12 male (18.8%) and three female (8.1%). Using the IDF criteria, MS was diagnosed in 16 patients (15.8%); 15 male (23.4%) and one female (2.7%). Conclusion: The prevalence of MS differed according to the NCEP criteria used, which had different cut-off points for waist circumference (14.9,23.8%). By the IDF criteria, which cites central obesity as an essential component, the prevalence of MS was slightly lower. Furthermore, in our study, MS was more prevalent in male renal transplant recipients. [source]

    The Impact of the Components of Metabolic Syndrome on Heart Rate Variability: Using the NCEP-ATP III and IDF Definitions

    Background: This study examined the relationship between metabolic syndrome (MetS) and heart rate variability (HRV) in Korean adults. Methods: Data were collected from family health examinations performed from December 2003 through January 2004, and 1,041 subjects consisting of males and females aged 20,87 years were included in this study. Measurement of the 5-minute HRV and several examinations for MetS were completed. The HRV was analyzed in both the time domain with the standard deviation of NN (SDNN) intervals and the frequency domain with the low frequency (LF) and high frequency (HF) components. MetS was defined by the criteria of the National Cholesterol Education Program's Adult Treatment Panel III (NCEP-ATP III) and the International Diabetes Federation (IDF). Results: There were significant differences in the MetS components and HRV indices between the two groups (with vs without MetS). The adjusted means of the HRV indices in the group with MetS were significantly lower than those in the group without MetS (P < 0.05). Furthermore, a significant negative correlation was found between all components of MetS and the HRV indices; additionally, as the number of MetS components increased, the HRV indices gradually decreased. Conclusions: Decreased cardiac autonomic tone was strongly associated with an increased cardiovascular risk, and HRV measurement could become an indispensable part of evaluating one's risk of cardiovascular disease, though we currently do not have sufficient information to identify the cutoff values for the HRV indices. [source]

    Relationship of abdominal obesity with cardiovascular disease, diabetes and hyperlipidaemia in Spain

    Felipe F. Casanueva
    Summary Objectives, To evaluate the relevance of obesity and abdominal obesity in the prevalence of cardiovascular disease (CVD), diabetes mellitus, hyperlipidaemia and hypertension in primary care patients and to ascertain whether waist circumference (WC) measurement should be included in routine clinical practice in addition to body mass index (BMI). Methods, As part of the IDEA study, primary care physicians from Spain recruited patients aged 18,80 years. WC and BMI and the presence of CVD, diabetes mellitus, hyperlipidaemia and hypertension were recorded. Finally, 17 980 were analysed. An age-related increase in adiposity was observed. Overall 33% were obese by BMI, and 51% of subjects presented abdominal obesity by the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATPIII) (WC > 102 cm for men and > 88 cm for women). Although there was a correlation between BMI and WC, they presented different distribution patterns. Women, but not men, with a high level of education, professional activity and smoking were associated with a lower WC. Abdominal obesity was significantly associated with CVD. Some subjects with abdominal obesity but lean by BMI, showed an increased prevalence of CVD and diabetes. Furthermore, abdominal obesity was strongly associated with dyslipidaemia and hypertension. Conclusions, Half of the primary care patients studied showed abdominal obesity as measured by WC, whereas one-third was obese by BMI. Abdominal obesity was strongly associated with CVD and diabetes, even in patients lean by BMI. WC should be included in the routine clinical practice in addition to BMI. [source]

    Insulin resistance and the metabolic syndrome in obese French children

    Céline Druet
    Summary Objective, To estimate the frequency of the metabolic syndrome (MS) and of the insulin resistance syndrome (IRS) in overweight or obese French children and to determine the risk factors. Design, patients and methods, A total of 308 overweight and obese children [166 girls, 142 boys, aged 7,17 years; median body mass index (BMI) 4ˇ7 standard deviation (SD) (Q1,Q3: 3ˇ9,5ˇ8) adjusted for age and sex] were included. The frequency of the MS was assessed with the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) criteria and the frequency of the IRS with World Health Organization (WHO) criteria. Results, The overall frequency of MS and IRS was 15ˇ9% and 42ˇ5%, respectively. The most common component, after abdominal obesity (95ˇ8%) and IR (71ˇ8%), was elevated systolic blood pressure (28ˇ6%). The frequency of glucose tolerance disorders was low (3ˇ6%). The frequency of MS was independently influenced by homeostatic model assessment (HOMA) (P = 0ˇ06) and waist-to-hip ratio (P = 0ˇ09), whereas the frequency of IRS was influenced by adiposity (degree of obesity: P = 0ˇ02; waist-to-hip ratio: P = 0ˇ05), puberty (P = 0ˇ05) and mother's BMI (P = 0ˇ01). Ethnicity had no effect on either MS or IRS. Conclusions, Metabolic complications and IR are frequent in overweight and obese children whereas the frequency of glucose tolerance disorders is very low. IRS is more prevalent than MS, indicating a major role of IR, which could precede the other metabolic complications in obese children. IRS is a relevant marker for the risk of type 2 diabetes (T2D) and cardiovascular complications in obese European children. [source]