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Tracking Changes (tracking + change)
Selected AbstractsTracking Changes in Jack London's Representation of the Railroad TrampTHE JOURNAL OF AMERICAN CULTURE, Issue 2 2007Christine Photinos First page of article [source] Conservation Status as a Biodiversity Trend Indicator: Recommendations from a Decade of Listing Species at Risk in British ColumbiaCONSERVATION BIOLOGY, Issue 4 2005JAMES F. QUAYLE especies amenazadas; especies en peligro; estado del ambiente Abstract:,Species conservation status is commonly used as a broad-scale indicator of the state of biological diversity. To learn about its value for tracking trends, we examined provincial lists of terrestrial vertebrate species and subspecies at risk in British Columbia, Canada, for 1992 and 2002 to see whether changes in these lists reflected changes in the status of the taxa they represent. Examination of the case histories of individual species and subspecies showed that 65% of additions and deletions to the British Columbia Red List were the result of improvement in knowledge of species status, changes in assessment procedures, and refinements in taxonomy rather than actual changes in a species' status. Comparison to an alternate set of rank scores provided by NatureServe for taxa that appeared on both 1992 and 2002 British Columbia Red Lists revealed changes in status that were not reflected by movement from the list. Estimates of historical conservation status for species on the 1992 British Columbia Red List demonstrated ambiguity around the natural baseline with regard to tracking changes in list composition over time. We discourage the continued use of indicators based solely on conservation status as a means of tracking biodiversity. Instead we recommend advancing strategic indicators around species at risk based on long-term monitoring data, deliberate and explicitly stated baselines, and consistent methods of conservation ranking. Resumen:,El estatus de conservación de las especies comúnmente es utilizado como un indicador de escala amplia del estado de la diversidad biológica. En un esfuerzo por aprender sobre su valor para el seguimiento de tendencias, examinamos listas provinciales, para 1992 y 2002, de especies y subespecies de vertebrados terrestres en riesgo en Columbia Británica, Canadá, para ver si los cambios en estas listas reflejaban cambios en el estatus de los taxa que representan. El examen de la historia del caso de especies y subespecies individuales mostró que 65% de las adiciones y supresiones en la Lista Roja de Columbia Británica fueron el resultado de avances en el conocimiento del estatus de la especie, de cambios en los procedimientos de evaluación y de refinamientos en la taxonomía y no de cambios en el estatus de una especie. La comparación con un conjunto alternativo de valores de clasificación proporcionado por NatureServe para taxa que aparecieron tanto en la Lista Roja de Columbia Británica de 1992 como de 2002 reveló cambios en el estatus que no se reflejaron en movimientos en la lista. Estimaciones del estatus de conservación histórico de especies en la Lista Roja de Columbia Británica de 1992 demostraron ambigüedad alrededor de la línea de base natural en relación con el seguimiento de cambios en el tiempo en la composición de la lista. Desalentamos el uso continuo de indicadores basados solamente en el estatus de conservación como un medio para el seguimiento de biodiversidad. En cambio, recomendamos avanzar con indicadores estratégicos en torno a especies en riesgo con base en datos de monitoreo de largo plazo, en líneas básicas puestas de manifiesto deliberada y explícitamente y en métodos consistentes para la clasificación de la conservación. [source] PERSPECTIVE: PURGING THE GENETIC LOAD: A REVIEW OF THE EXPERIMENTAL EVIDENCEEVOLUTION, Issue 12 2002Peter Crnokrak Abstract., Inbreeding depression, the reduction in fitness that accompanies inbreeding, is one of the most important topics of research in evolutionary and conservation genetics. In the recent literature, much attention has been paid to the possibility of purging the genetic load. If inbreeding depression is due to deleterious alleles, whose effect on fitness are negative when in a homozygous state, then successive generations of inbreeding may result in a rebound in fitness due to the selective decrease in frequency of deleterious alleles. Here we examine the experimental evidence for purging of the genetic load by collating empirical tests of rebounds in fitness-related traits with inbreeding in animals and plants. We gathered data from 28 studies including five mammal, three insect, one mollusc, and 13 plant species. We tested for purging by examining three measures of fitness-component variation with serial generations of inbreeding: (1) changes in inbreeding depression, (2) changes in fitness components of inbred lines relative to the original outbred line, and (3) purged population (outcrossed inbred lines) trait means as a function of ancestral outbred trait means. Frequent and substantial purging was found using all three measures, but was particularly pronounced when tracking changes in inbreeding depression. Despite this, we found little correspondence between the three measures of purging within individual studies, indicating that the manner in which a researcher chooses to estimate purging will affect interpretation of the results obtained. The discrepancy suggests an alternative hypothesis: rebounds in fitness with inbreeding may have resulted from adaptation to laboratory conditions and not to purging when using outcrossed inbred lines. However, the pronounced reduction in inbreeding depression for a number of studies provides evidence for purging, as the measure is likely less affected by selection for laboratory conditions. Unlike other taxon-specific reviews on this topic, our results provide support for the purging hypothesis, but firm predictions about the situations in which purging is likely or the magnitude of fitness rebound possible when populations are inbred remain difficult. Further research is required to resolve the discrepancy between the results obtained using different experimental approaches. [source] Understanding future ecosystem changes in Lake Victoria basin using participatory local scenariosAFRICAN JOURNAL OF ECOLOGY, Issue 2009Eric O. Odada Abstract Understanding future ecosystem changes is central to sustainable natural resource management especially when coupled with in-depth understanding of impacts of drivers, such as governance, demographic, economic and climate variations and land use policy. This offers comprehensive information for sustainable ecosystem services provision. A foresight process of systematic and presumptive assessment of future state and ecosystem integrity of Lake Victoria basin, as participatory scenario building technique, is presented. Four scenarios have been illustrated as possible future states of the basin over the next twenty years. Using a scenario building model developed in Ventana Simulation (VENSIM®) platform, the paper presents a scenario methodology for tracking changes in lake basin ecosystem status. Plausible trends in land use change, changes in lake levels and contribution of fisheries are presented. This is part of an initial attempt to setup long-term environmental policy planning strategies for Lake Victoria basin. The assumptions, driving forces, impacts and opportunities under each scenario depict major departure and convergence points for an integrated transboundary diagnosis and analysis of regional issues in the basin as well as strategic action planning for long-term interventions. The findings have been presented in terms of temporal, spatial, biophysical and human well-being dimensions. The attempts in this study can be embedded in a policy framework for basin management priority setting and may guide partnerships for environmental management. [source] Comparison of calibrated and uncalibrated arterial pressure,based cardiac output monitors during orthotopic liver transplantation,LIVER TRANSPLANTATION, Issue 6 2010Vladimir Krejci Arterial pressure,based cardiac output monitors (APCOs) are increasingly used as alternatives to thermodilution. Validation of these evolving technologies in high-risk surgery is still ongoing. In liver transplantation, FloTrac-Vigileo (Edwards Lifesciences) has limited correlation with thermodilution, whereas LiDCO Plus (LiDCO Ltd.) has not been tested intraoperatively. Our goal was to directly compare the 2 proprietary APCO algorithms as alternatives to pulmonary artery catheter thermodilution in orthotopic liver transplantation (OLT). The cardiac index (CI) was measured simultaneously in 20 OLT patients at prospectively defined surgical landmarks with the LiDCO Plus monitor (CIL) and the FloTrac-Vigileo monitor (CIV). LiDCO Plus was calibrated according to the manufacturer's instructions. FloTrac-Vigileo did not require calibration. The reference CI was derived from pulmonary artery catheter intermittent thermodilution (CITD). CIV -CITD bias ranged from ,1.38 (95% confidence interval = ,2.02 to ,0.75 L/minute/m2, P = 0.02) to ,2.51 L/minute/m2 (95% confidence interval = ,3.36 to ,1.65 L/minute/m2, P < 0.001), and CIL -CITD bias ranged from ,0.65 (95% confidence interval = ,1.29 to ,0.01 L/minute/m2, P = 0.047) to ,1.48 L/minute/m2 (95% confidence interval = ,2.37 to ,0.60 L/minute/m2, P < 0.01). For both APCOs, bias to CITD was correlated with the systemic vascular resistance index, with a stronger dependence for FloTrac-Vigileo. The capability of the APCOs for tracking changes in CITD was assessed with a 4-quadrant plot for directional changes and with receiver operating characteristic curves for specificity and sensitivity. The performance of both APCOs was poor in detecting increases and fair in detecting decreases in CITD. In conclusion, the calibrated and uncalibrated APCOs perform differently during OLT. Although the calibrated APCO is less influenced by changes in the systemic vascular resistance, neither device can be used interchangeably with thermodilution to monitor cardiac output during liver transplantation. Liver Transpl 16:773-782, 2010. © 2010 AASLD. [source] Comparison of the USCOM ultrasound cardiac output monitor with pulmonary artery catheter thermodilution in patients undergoing liver transplantation,LIVER TRANSPLANTATION, Issue 7 2008Lai-Sze Grace Wong The aim of the study was to compare the standard technique of cardiac output determination by pulmonary artery catheter thermodilution (PAC-TD) with a noninvasive ultrasound Doppler monitor (USCOM Pty., Ltd., Coffs Harbour, Australia) in surgery for liver transplantation. We wished to determine if the degree of accuracy would allow the ultrasound cardiac output monitor (USCOM) to be used as an alternative monitor in a clinical setting in which wide fluctuations in cardiac output could be expected. This was a prospective method comparison study, with 71 paired measurements obtained in 12 patients undergoing liver transplantation in a university teaching hospital. Bland-Altman analysis of the 2 techniques showed a bias of 0.39 L/minute, with the USCOM cardiac output lower compared with that of PAC-TD. The bias was small and did not vary with the magnitude of the cardiac output. The 95% limits of agreement were ,1.47 and 2.25 L/minute. There was good repeatability for USCOM measurements, with a repeatability coefficient of 0.43 for USCOM versus 0.77 for PAC-TD. We conclude that USCOM is acceptable for the clinical determination of noninvasive cardiac output, particularly in situations in which tracking changes over time is more important than knowing the precise value. However, the utility of USCOM is limited by its inability to measure pulmonary artery pressure. Liver Transpl 14:1038,1043, 2008. © 2008 AASLD. [source] A rapid way of tracking changes in cell wall polymers during biofuel productionBIOTECHNOLOGY & BIOENGINEERING, Issue 3 2010Article first published online: 23 DEC 200 No abstract is available for this article. [source] Automated classification of Plasmodium sporozoite movement patterns reveals a shift towards productive motility during salivary gland infectionBIOTECHNOLOGY JOURNAL, Issue 6 2009Stephan Hegge Abstract The invasive stages of malaria and other apicomplexan parasites use a unique motility machinery based on actin, myosin and a number of parasite-specific proteins to invade host cells and tissues. The crucial importance of this motility machinery at several stages of the life cycle of these parasites makes the individual components potential drug targets. The different stages of the malaria parasite exhibit strikingly diverse movement patterns, likely reflecting the varied needs to achieve successful invasion. Here, we describe a Tool for Automated Sporozoite Tracking (ToAST) that allows the rapid simultaneous analysis of several hundred motile Plasmodium sporozoites, the stage of the malaria parasite transmitted by the mosquito. ToAST reliably categorizes different modes of sporozoite movement and can be used for both tracking changes in movement patterns and comparing overall movement parameters, such as average speed or the persistence of sporozoites undergoing a certain type of movement. This allows the comparison of potentially small differences between distinct parasite populations and will enable screening of drug libraries to find inhibitors of sporozoite motility. Using ToAST, we find that isolated sporozoites change their movement patterns towards productive motility during the first week after infection of mosquito salivary glands. [source] In vitro susceptibility of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis: a European multicenter study during 2000,2001CLINICAL MICROBIOLOGY AND INFECTION, Issue 7 2003M. E. Jones Objective, To assess the current (2001) activity of respiratory fluoroquinolones and comparator agents against respiratory pathogens isolated in European countries. Methods, During 2000,2001, we prospectively collected 1995 isolates of Haemophilus influenzae, 1870 isolates of Streptococcus pneumoniae and 649 isolates of Moraxella catarrhalis from hospital laboratories in France, Germany, Greece, Italy, Spain and the UK. National Committee for Clinical Laboratory Standards (NCCLS)-approved broth microdilution antimicrobial susceptibility testing methods and interpretive criteria were used throughout. Results, Of the S. pneumoniae isolates, 99.6% were susceptible to moxifloxacin, gatifloxacin and levofloxacin; the corresponding figure for H. influenzae was 100%. All M. catarrhalis isolates had moxifloxacin MICs ,,0.12 mg/L. For all three pathogens, fluoroquinolone susceptibility remained unchanged from the previous 1997,98 study. The incidence of penicillin non-susceptibility in the S. pneumoniae isolates tested remained similar to or higher than that recorded in previous studies: France, 165/291 (56.7%); Germany, 46/506 (9.1%); Greece, 20/55 (36.4%); Italy, 45/364 (12.4%); Spain, 146/268 (54.5%); and the UK, 26/386 (6.7%). Significant levels of resistance to oral compounds (cefuroxime, cefaclor, cefdinir, clarithromycin, azithromycin, tetracycline, and trimethoprim,sulfamethoxazole) were detected among S. pneumoniae isolates. ,-Lactamase production among H. influenzae isolates ranged from 6.2% to 33.1% per country, and ampicillin, clarithromycin or trimethoprim,sulfamethoxazole resistance were the most common phenotypes detected. ,-Lactamase production among M. catarrhalis isolates ranged from 94.1% to 100% per country. Conclusions, With the exception of a few localized reports, resistance to moxifloxacin and other new fluoroquinolones in common respiratory pathogens is a rare occurrence, despite significant resistance to other compound classes. Surveillance will play a key role in tracking changes in fluoroquinolone susceptibility in European countries. [source] | |||||||||||||