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Total Excision (total + excision)

Distribution by Scientific Domains
Medical Sciences100%
Distribution within Medical Sciences
Dermatology42%
Surgery & Surgical Specialties28%

Selected Abstracts

Multiple pilomatricoma with perforation

INTERNATIONAL JOURNAL OF DERMATOLOGY, Issue 12 2002
Emel Fetil MD
A 22-year-old woman presented to our clinic with a complaint of masses on various parts of her body. A mass on her right forearm had appeared 5 years ago and had enlarged during the past 6 months. Two lesions on the back of her neck had a 3-year history, one lesion on her eyebrow had a 2-year history, and one lesion on her left forearm had a 1-year history. The lesion on her left forearm was discharging purulent material. Dermatologic examination revealed a 15 × 16 mm tumor on the right forearm, 11 × 6 mm and 10 × 5 mm tumors on the back of the neck, and a 20 × 20 mm tumor on the eyebrow; they were flesh-colored, well-defined, firm tumors. On her left forearm, there was a 12 × 10 mm, well-defined, firm, blue,red tumor discharging chalky white granules; purulent material was detected (Fig. 1). Figure 1. Firm, blue,red tumor discharging chalky white granules There was no regional lymphadenopathy. Systemic examination was normal. Laboratory examination of hematologic, biochemical, and urinalysis tests was normal. There was no family history of similar lesions. Total excision of all the tumors was performed. Histopathologic examination of the material revealed clusters of eosinophilic shadow cells surrounded by a fibrous capsule. There were also foreign body giant cells. Areas of calcification, cholesterol clefts, and ossification were detected. An intraepidermal perforating area was detected from the biopsy material of the left forearm (Fig. 2). There were no recurrences after 1 year of follow-up. Figure 2. Intraepidermal perforating area and clusters of shadow cells (hematoxylin and eosin, × 200) [source]

Primary cancer of the sphenoid sinus,A GETTEC study,

HEAD & NECK: JOURNAL FOR THE SCIENCES & SPECIALTIES OF THE HEAD AND NECK, Issue 3 2009
Pierre Olivier Vedrine MD
Abstract Background. Primary involvement of the sphenoid sinus occurs in 2% of all paranasal sinus tumors and is associated with dismal prognosis. Optimal management remains debatable. Methods. A total of 23 patients were treated for a primary cancer of the sphenoid sinus from 1988 to 2004. Charts were reviewed for patient-, tumor-, and treatment-related parameters. Univariate and multivariate analyses were conducted to identify prognostic factors for locoregional control and survival. Results. Cranial neuropathies were present in 12 patients. Pathologic findings included adenoid cystic carcinoma, adenocarcinoma, lymphoma, squamous cell carcinoma, sarcoma, neuroendocrine carcinoma, melanoma, and malignant hemangiopericytoma. All but 2 patients had stages III to IV cancer. Radiotherapy was performed in 18 patients and chemotherapy in 12. Of 10 patients undergoing surgery, total excision with grossly negative margins was achieved in 4 patients and subtotal resection in 6. Median locoregional control and overall survival were 12 and 41 months, respectively. On multivariate analysis, cranial neuropathy was associated with worse locoregional control and survival. Surgery was rarely complete because of advanced stages at presentation, but it yielded better outcomes than other treatments without surgery in non lymphoma-cases. Conclusion. Early CT and MRI should be performed when facing aspecific, rhinological, or neuro-ophtalmological symptoms. Cranial neuropathies indicate a worse prognosis. Surgery, including debulking surgery, may be preferred to combined modality treatments without surgery. Its apparently favorable impact on prognosis would need to be tested in homogenous histological groups of patients, which is impossible because of the rarity of the disease. Highly conformal radiotherapy (adjuvant or definitive) should be encouraged and optimized with concurrent chemotherapy in advanced stages. Aggressive multidisciplinary management including surgery, chemotherapy, and radiotherapy should be encouraged and adapted on histology and tumor extensions. Progress is still warranted to improve outcomes. © 2008 Wiley Periodicals, Inc. Head Neck, 2009 [source]

Stop female genital mutilation: appeal to the international dermatologic community

INTERNATIONAL JOURNAL OF DERMATOLOGY, Issue 5 2002
Aldo Morrone MD
Female genital mutilation (FGM) is a traditional cultural practice, but also a form of violence against girls, which affects their lives as adult women. FGM comprises a wide range of procedures: the excision of the prepuce; the partial or total excision of the clitoris (clitoridectomy) and labia; or the stitching and narrowing of the vaginal orifice (infibulation). The number of girls and women who have been subjected to FGM is estimated at around 137 million worldwide and 2 million girls per year are considered at risk. Most females who have undergone mutilation live in 28 African countries. Globalization and international migration have brought an increased presence of circumcised women in Europe and developed countries. Healthcare specialists need to be made aware and trained in the physical, psychosexual, and cultural aspects and effects of FGM and in the response to the needs of genitally mutilated women. Health education programs targeted at immigrant communities should include information on sexuality, FGM, and reproduction. Moreover, healthcare workers should both discourage women from performing FGM on their daughters and receive information on codes of conduct and existing laws. The aim is the total eradication of all forms of FGM. [source]

Squamous cell carcinoma: a rare complication of dermoid cysts

NEUROPATHOLOGY & APPLIED NEUROBIOLOGY, Issue 2 2002
K. Ashkan
Introduction:, Dermoid cysts constitute 0.3% of all brain tumours. Carcinomatous differentiation has been described only in a handful of cases. Material and methods:, A 44-year-old-man presented with a several-year history of headaches and a 5-week history of progressive visual deterioration in the left eye. Clinical examination confirmed a normal visual acuity but an impaired left visual field. A magnetic resonance imaging scan showed a lesion in the left paraclinoid area compressing the ipsilateral optic nerve. Signal characteristics of the lesion were consistent with a dermoid or epidermoid cyst. At operation, the lesion was thought to be typical of a dermoid cyst and a near-complete excision was achieved leaving behind parts adherent to the optic nerve. Histology showed invasive squamous cell carcinoma arising within the dermoid tumour. Postoperatively the patient received radiotherapy. Results:, The patient's clinical condition initially stabilized. At 15 months follow up, however, there was clinical and radiological evidence of tumour progression and he died 1 year later. Conclusion:, Squamous cell carcinoma may rarely arise from an intracranial dermoid tumour. This may hinder total excision of the lesion and confounds the prognosis. [source]

Primary bronchopulmonary leiomyosarcoma of the left main bronchus in a child presenting with wheezing and atelectasis of the left lung

PEDIATRIC PULMONOLOGY, Issue 4 2002
Dong-Shang Lai M.D.
Abstract Primary lung tumors are rare in children, and primary bronchopulmonary leiomyosarcomas are very rare in children, with only 10 cases reported in the English-language literature. We report on the eleventh case of primary bronchopulmonary leiomyosarcoma in a child, and it is the first case in Taiwan, and also in Asia. In addition, this is the second case of this tumor arising in the left main bronchus. Before the present case, there were only 2 cases of this tumor in the main bronchus: one was in the right main-stem bronchus, and the other in the left-stem main bronchus. Ours is the second case showing pleural effusion. Chest roentgenogram and bronchoscopy are helpful in the diagnosis of primary bronchopulmonary tumors, but a definitive diagnosis can only be made by biopsy. The tumor is potentially curable if total excision is possible; irradiation has little therapeutic value, and early excision offers the only hope of cure. The child is alive and well 19 months after pneumonectomy, without having received radiotherapy or chemotherapy. Pediatr Pulmonol. 2002; 33:318-321. © 2002 Wiley-Liss, Inc. [source]

A case of perforating pilomatricoma

THE JOURNAL OF DERMATOLOGY, Issue 6 2006
Harun CIRALIK
ABSTRACT Pilomatricoma is a rare skin neoplasm, most commonly seen in the head and neck region, and occurring in the first two decades of life. It is usually solitary and varies from 0.5 to 2 cm in diameter. Its etiology is unknown. Perforating pilomatricoma is a rare clinical variant that presents as a draining, crusted nodule or ulcer, and is reported to arise faster than the classic pilomatricoma. Herein, we report a case of 35-year-old female, who had a 4-month history of a growing mass on her leg. On physical examination, a 4-cm diameter, asymptomatic, erythematous, ulcerated mass was noted on the left anterio-lateral upper leg. The first histopathological analysis of a punch biopsy from the lesion was reported as basal cell carcinoma. Therefore, the lesion was totally excised. There were shadow cells, squamoid cells, and basaloid aggregations more prominently in the one area in the tumor. In addition, calcification, foreign body giant cells and inflammatory cells were present. Punch or excisional biopsies are preferred as a method of diagnosis for the majority of cutaneous neoplasms. If total excision is not the method of choice, multiple punch biopsies should be made from different areas in large skin tumors for correct diagnosis. [source]

Resection of the rectum and total excision of the internal anal sphincter with smooth muscle plasty and colonic pouch for treatment of ultralow rectal carcinoma,

BRITISH JOURNAL OF SURGERY (NOW INCLUDES EUROPEAN JOURNAL OF SURGERY), Issue 11 2004
G. I. Vorobiev
Background: Intersphincteric resection can provide tumour-free margins for rectal tumours located 0,1 cm above the dentate line. However, the internal anal sphincter (IAS) is partially or totally resected and some degree of anal incontinence may develop. A novel technique of smooth muscle plasty of the IAS and colonic pouch construction is described, along with an assessment of morbidity, oncological results and functional outcome. Patients and methods: Between 1997 and 2002, 27 patients (16 men; median age 55 (range 26,75) years) were operated on for T2,3 N0,1 M0 rectal carcinoma located a median of 1·0 (range 0·5,1·5) cm from the dentate line. Resection of the IAS was performed transanally. A smooth muscle cuff, fashioned from the muscular layer of colon, and a colonic pouch were used for anorectal reconstruction. Results: There were no perioperative deaths. Anastomotic leakage developed in two patients. After a median follow-up of 38 (range 14,66) months no local recurrence was detected. Distant metastases occurred in three patients, two of whom died. Perfect functional outcome was achieved in 22 of 26 patients. At 6 months after surgery the mean(s.d.) resting anal pressure was 49(8) mmHg. Conclusion: In selected patients intersphincteric resection does not compromise the oncological result. The suggested anorectal reconstruction may improve the functional outcome. Copyright © 2004 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. [source]