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Kinds of Time Span Selected AbstractsMental health improvements of substance-dependent clients after 4 months in a Therapeutic CommunityDRUG AND ALCOHOL REVIEW, Issue 5 2010ANNE-MAREE POLIMENI Abstract Introduction and Aims. Odyssey House Victoria's Therapeutic Community (TC) accepts substance-dependent clients, including those with co-occurring mental health issues. American data suggest that TCs are effective in rehabilitating such clients; however, Australian research is limited. The aim of the study was to examine Minnesota Multiphasic Personality Inventory-2 (MMPI-2) profiles of Odyssey House TC residents early in their residency and again after 4 months, to chart changes in MMPI-2 profiles and compare them with norms for psychological health. Design and Methods. The sample comprised 351 clients who were part of the residential program between 1997 and 2007, and who remained in treatment at the TC for at least 4 months. They were administered the MMPI-2 after 5 weeks in treatment and again after 4 months. Results. At the first assessment, the validity scales of the MMPI-2 plus the clinical scales Depression, Psychopathic Deviate, Paranoia, Psychasthenia and Schizophrenia were in the clinical range. At the second assessment, mean scores on all clinical scales except Mania were significantly or near significantly lower and, except for Psychopathic Deviate, within the normal range. The validity scales also demonstrated improvement, although two of the three remained in the clinical range. Discussion and Conclusions. Results indicated that treatment within the TC over this time span was associated with improved mental health. The present study suggests that residential rehabilitation's holistic approach provides a suitable treatment model for clients with co-occurring mental health and substance use disorders.[Polimeni A-M, Moore SM, Gruenert S. Mental health improvements of substance-dependent clients after 4 months in a Therapeutic Community. Drug Alcohol Rev 2010] [source] Quantifying sediment storage in a high alpine valley (Turtmanntal, Switzerland)EARTH SURFACE PROCESSES AND LANDFORMS, Issue 13 2009Jan-Christoph Otto Abstract The determination of sediment storage is a critical parameter in sediment budget analyses. But, in many sediment budget studies the quantification of magnitude and time-scale of sediment storage is still the weakest part and often relies on crude estimations only, especially in large drainage basins (>100,km2). We present a new approach to storage quantification in a meso-scale alpine catchment of the Swiss Alps (Turtmann Valley, 110,km2). The quantification of depositional volumes was performed by combining geophysical surveys and geographic information system (GIS) modelling techniques. Mean thickness values of each landform type calculated from these data was used to estimate the sediment volume in the hanging valleys and the trough slopes. Sediment volume of the remaining subsystems was determined by modelling an assumed parabolic bedrock surface using digital elevation model (DEM) data. A total sediment volume of 781·3×106,1005·7×106,m3 is deposited in the Turtmann Valley. Over 60% of this volume is stored in the 13 hanging valleys. Moraine landforms contain over 60% of the deposits in the hanging valleys followed by sediment stored on slopes (20%) and rock glaciers (15%). For the first time, a detailed quantification of different storage types was achieved in a catchment of this size. Sediment volumes have been used to calculate mean denudation rates for the different processes ranging from 0·1 to 2·6,mm/a based on a time span of 10,ka. As the quantification approach includes a number of assumptions and various sources of error the values given represent the order of magnitude of sediment storage that has to be expected in a catchment of this size. Copyright © 2009 John Wiley & Sons, Ltd. [source] Scale dependence of spatial patterns and cartography on the detection of landscape change: relationships with species' perceptionECOGRAPHY, Issue 4 2002Susana Suárez-Seoane This paper analyses how landscape pattern detection changes when different spatial and temporal scales and several levels of detail of the cartography are used to describe a landscape affected by land abandonment in northern Spain. In order to integrate landscape composition and structure at different temporal and spatial scales in the same framework, a multiple correspondence factorial analysis was ran for each typology of landscape units. Annual rates of change and scale dependencies were calculated for each typology from the Euclidean distances in the factorial space. Finally, the potential assessment of habitat utilisation by species with different landscape perception and movement capacity was modelled for the range of typologies. The amount of variance explained by the factorial analysis decreased with the complexity of the typology. Annual rates of change appeared different according to the time span and the detail of the landscape unit typology used. For all typologies, changes were faster during 1983,95, a period characterised by massive land abandonment. However, when the whole period (1956,95) was considered, annual changes were much lower, showing differences between typologies. As a general trend, the variance of the mean annual change decreased with the size of the analysis units. In response to land abandonment, different scale dependencies were found for different levels of detail of the cartography. Coarser typologies are suitable when analysing highly mobile species. However, species with small movement capacity or with a preference for homogeneous habitats perceive more detail in landscape. In this case, a detailed typology is more appropriate. [source] Transplacental mutagenicity of N -ethyl- N -nitrosourea at the hprt locus in T-lymphocytes of exposed B6C3F1 miceENVIRONMENTAL AND MOLECULAR MUTAGENESIS, Issue 1 2001Hillary E. Sussman Abstract Previous studies have compared age-related differences in total mutagenic burden in mice of differing age (preweanling, weanling, or young adult) after single intraperitoneal (i.p.) injections of ethylnitrosourea (ENU). The purpose of the present investigation was to determine the effects of time elapsed since treatment on the frequency of hprt mutant T-cells (Mf) from mice treated transplacentally with single acute vs. multiple split doses of ENU. To this end, pregnant C57BL/6 mice (n = 13,16/group), which had been bred to C3H males, were given i.p. injections of 40 mg ENU/kg bw in a single dose on day 18 of gestation, in a split dose of 6 mg ENU/kg bw on days 12 through 18 of gestation, or DMSO vehicle alone. Groups of pups were necropsied on days 10, 13, 15 (single dose only), 17, 20, 40, and 70 postpartum for T-cell isolations and hprt Mf measurements using the T-cell cloning assay. The time required to reach maximum Mfs in T-cells isolated from thymus of transplacentally treated animals was 2 weeks, the same time span as previously observed after ENU treatment of adult, weanling, and preweanling mice. Mfs in T-cells isolated from spleens of control animals averaged 2.1 ± 0.3 (SE) × 10,6. In spleens of mice treated transplacentally with ENU in a single dose, Mfs reached a maximum at 15 days postpartum [84.7 ± 15.8 (SE) × 10,6] and decreased to lower but still elevated levels at 40 days postpartum. In spleens of mice treated transplacentally with ENU in a split dose, Mfs reached a maximum at 13 days postpartum [74.0 ± 16.3 (SE) × 10,6] and decreased to background levels at 40 days postpartum. The areas under the curves describing the change in hprt Mfs over time for ENU-treated vs. control mice estimate the mutagenic potency for transplacental single- and split-dose exposures to be 1.9 and 0.8 × 103, respectively. Comparison of the mutagenic potency estimates for mice exposed to ENU in utero to 4-week-old mice given a similar dose of the same lot number of ENU indicates that the mouse is more susceptible to ENU-induced mutagenesis during fetal life. Environ. Mol. Mutagen. 38:30,37, 2001 © 2001 Wiley-Liss, Inc. [source] Procrastination as self-regulation failure of performance: effects of cognitive load, self-awareness, and time limits on ,working best under pressure'EUROPEAN JOURNAL OF PERSONALITY, Issue 5 2001Joseph R. Ferrari Effects of cognitive load, objective self-awareness and time limits on the self-regulation of performance speed and accuracy were investigated between procrastinators and non-procrastinators. In experiment 1 chronic procrastinators completed fewer items (slow speed) and made more errors (less accuracy) than non-procrastinators under high but not low cognitive load conditions when the time span was limited and brief. In experiment 2 chronic procrastinators performed slower than non-procrastinators under a 2 second, but not under no limit, 1 second, or 4 second time limit conditions. Chronic procrastinators compared to non-procrastinators also performed more slowly and made more performance errors under objective self-awareness conditions regardless of the length of time. These experiments indicate that chronic procrastinators regulate ineffectively their performance speed and accuracy when they ,work under pressure' (defined by high cognitive load, objective self-awareness, and imposed time limitations). Copyright © 2001 John Wiley & Sons, Ltd. [source] Human evolution at the Matuyama-Brunhes boundaryEVOLUTIONARY ANTHROPOLOGY, Issue 1 2004Article first published online: 12 FEB 200, Giorgio Manzi Abstract The cranial morphology of fossil hominids between the end of the Early Pleistocene and the beginning of the Middle Pleistocene provides crucial evidence to understand the distribution in time and space of the genus Homo. This evidence is critical for evaluating the competing models regarding diversity within our genus. The debate focuses on two alternative hypotheses, one basically anagenetic and the other cladogenetic. The first suggests that morphological change is so diffused, slow, and steady that it is meaningless to apply species names to segments of a single lineage. The second is that the morphological variation observed in the fossil record can best be described as a number of distinct species that are not connected in a linear ancestor-descendant sequence. Today much more fossil evidence is available than was in the past to test these alternative hypotheses, as well as intermediate variants. Special attention must be paid to Africa because this is the most probable continental homeland for both the origin of the genus Homo (around 2.5,2 Ma),1 as well as the site, two million or so years later, of the emergence of the species H. sapiens.2 However, the African fossil record is very poorly represented between 1 Ma and 600 ka. Europe furnishes recent discoveries in this time range around the Matuyama-Brunhes chron boundary (780,000 years ago), a period for which, at present, we have no noteworthy fossil evidence in Africa or the Levant. Two penecontemporaneous sources of European fossil evidence, the Ceprano calvaria (Italy)3 and the TD6 fossil assemblage of Atapuerca (Spain)4 are thus of great interest for testing hypotheses about human evolution in the fundamental time span bracketed between the late Early and the Middle Pleistocene. This paper is based on a phenetic approach to cranial variation aimed at reviewing the Early-to-Middle Pleistocene trajectories of human evolution. The focus of the paper is on neither the origin nor the end of the story of the genus Homo, but rather its chronological and phylogenetic core. Elucidation of the evolutionary events that happened around 780 ka during the transition from the Early to Middle Pleistocene is one of the new frontiers for human paleontology, and is critical for understanding the processes that ultimately led to the origin of H. sapiens. [source] Aboveground plant biomass, carbon, and nitrogen dynamics before and after burning in a seminatural grassland of Miscanthus sinensis in Kumamoto, JapanGCB BIOENERGY, Issue 2 2010YO TOMA Abstract Although fire has been used for several thousand years to maintain Miscanthus sinensis grasslands in Japan, there is little information about the nutrient dynamics in these ecosystems immediately after burning. We investigated the loss of aboveground biomass; carbon (C) and nitrogen (N) dynamics; surface soil C change before and after burning; and carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) fluxes 2 h after burning in a M. sinensis grassland in Kumamoto, Japan. We calculated average C and N accumulation rates within the soil profile over the past 7300 years, which were 58.0 kg C ha,1 yr,1 and 2.60 kg N ha,1 yr,1, respectively. After burning, 98% of aboveground biomass and litter were consumed. Carbon remaining on the field, however, was 102 kg C ha,1. We found at least 43% of C was possibly lost due to decomposition. However, remaining C, which contained ash and charcoal, appeared to contribute to C accumulation in soil. There was no difference in the amount of 0,5 cm surface soil C before and after burning. The amount of remaining litter on the soil surface indicated burning appeared not to have caused a reduction in soil C nor did it negatively impact the sub-surface vegetative crown of M. sinensis. Also, nearly 50 kg N ha,1 of total aboveground biomass and litter N was lost due to burning. Compared with before the burning event, postburning CO2 and CH4 fluxes from soil appeared not to be directly affected by burning. However, it appears the short time span of measurements of N2O flux after burning sufficiently characterized the pattern of increasing N2O fluxes immediately after burning. These findings indicate burning did not cause significant reductions in soil C nor did it result in elevated CO2 and CH4 emissions from the soil relative to before the burning event. [source] FxJj43: A window into a 1.5-million-year-old palaeolandscape in the Okote Member of the Koobi Fora Formation, northern KenyaGEOARCHAEOLOGY: AN INTERNATIONAL JOURNAL, Issue 4 2002Nicola Stern FxJj43 differs from most other archaeological sites preserved in the Okote Member of the Koobi Fora Formation in ways that make it especially suited to the problem of clarifying the behavioral information encapsulated in fine time-lines. At this site in northern Kenya, a continuous strip of outcrops, preserving a set of interlocking landforms, can be traced around the modern erosion front for more than half a kilometer. The characteristics and three-dimensional geometries of the beds making up these outcrops show that they have preserved the southern bank, levee, and floodplain of a westerly flowing sandy channel. Both stone tools and animal bones are strewn across the eroding surfaces of these outcrops, and excavations show that they are derived from a narrow stratigraphic horizon immediately overlying the volcanic ash at the base of the sequence. The blue tuff, and the archaeological horizon that overlies it, have been dated using the 40Ar- 39Ar method on single crystals of alkali feldspar. Although there is no direct measure of how long it took the archaeological horizon to accumulate, it probably accumulated over a time span of 102,103 years. Thus the locality may be used to test the proposition that the analysis of archaeological debris from fine-time lines will help to resolve ambiguities in the interpretation of early Pleistocene archaeological assemblages. © 2002 Wiley Periodicals, Inc. [source] New insights from reactive transport modelling: the formation of the sericitic vein envelopes during early hydrothermal alteration at Butte, MontanaGEOFLUIDS (ELECTRONIC), Issue 3 2002S. Geiger Abstract A reactive transport computer code has been employed to model hydrothermal alteration of a granitoid rock bordering a discrete vein channel. The model suggests that the grey sericitic and sericitic with remnant biotite alteration envelopes at the porphyry copper deposit at Butte, Montana, can be formed by a reducing, low pH, and low salinity fluid under constant temperature and pressure conditions of approximately 400 °C and less than 100 MPa during a time span of approximately 100 years or less. Hydrothermal alteration has little effect on the porosity of the host rock (Butte Quartz Monzonite), and the diffusivity of the aqueous species also changes little. A sequence of mineral reaction fronts characterizes the alteration envelopes. The biotite dissolution front occurs closest to the vein channel and marks the transition from the grey sericitic to sericitic with remnant biotite envelope. The plagioclase dissolution front occurs farthest into the matrix and marks the edge of relatively fresh Butte Quartz Monzonite. From the properties of the quasi-stationary state approximation (Lichtner 1988; Lichtner 1991), it follows that once the sequence of reaction fronts is fully established, their relative locations remain constant and the widths of the reaction zones increase with the square root of time. [source] Mechanical deformation model of the western United States instantaneous strain-rate fieldGEOPHYSICAL JOURNAL INTERNATIONAL, Issue 1 2006Fred F. Pollitz SUMMARY We present a relationship between the long-term fault slip rates and instantaneous velocities as measured by Global Positioning System (GPS) or other geodetic measurements over a short time span. The main elements are the secularly increasing forces imposed by the bounding Pacific and Juan de Fuca (JdF) plates on the North American plate, viscoelastic relaxation following selected large earthquakes occurring on faults that are locked during their respective interseismic periods, and steady slip along creeping portions of faults in the context of a thin-plate system. In detail, the physical model allows separate treatments of faults with known geometry and slip history, faults with incomplete characterization (i.e. fault geometry but not necessarily slip history is available), creeping faults, and dislocation sources distributed between the faults. We model the western United States strain-rate field, derived from 746 GPS velocity vectors, in order to test the importance of the relaxation from historic events and characterize the tectonic forces imposed by the bounding Pacific and JdF plates. Relaxation following major earthquakes (M, 8.0) strongly shapes the present strain-rate field over most of the plate boundary zone. Equally important are lateral shear transmitted across the Pacific,North America plate boundary along ,1000 km of the continental shelf, downdip forces distributed along the Cascadia subduction interface, and distributed slip in the lower lithosphere. Post-earthquake relaxation and tectonic forcing, combined with distributed deep slip, constructively interfere near the western margin of the plate boundary zone, producing locally large strain accumulation along the San Andreas fault (SAF) system. However, they destructively interfere further into the plate interior, resulting in smaller and more variable strain accumulation patterns in the eastern part of the plate boundary zone. Much of the right-lateral strain accumulation along the SAF system is systematically underpredicted by models which account only for relaxation from known large earthquakes. This strongly suggests that in addition to viscoelastic-cycle effects, steady deep slip in the lower lithosphere is needed to explain the observed strain-rate field. [source] Magnetic polarity stratigraphy of Siwalik Group sediments of Karnali River section in western NepalGEOPHYSICAL JOURNAL INTERNATIONAL, Issue 3 2000Pitambar Gautam The remanent magnetization of siltstones and sandstones sampled at 476 levels/sites throughout a 3560 m thick molasse sequence belonging to the Siwalik Group (0,2015 m: Lower; 2015,3560 m: Middle) has been studied by stepwise thermal demagnetization. This section is exposed along the Karnali River in Nepal. The natural remanent magnetization (NRM) usually consists of two components: a viscous or thermoviscous component of recent field origin, and an ancient characteristic component (ChRM). The former component is of normal polarity and resides either in goethite (unblocking temperature < 150 °C; resistant to AFD up to 150 mT) or in maghemite (unblocking temperature 150,400 °C). Goethite contributes up to 90 per cent of the total intensity in the finer variegated muddy samples belonging to the lower half of the section. Maghemite content is significant in the grey mud-free lithologies from the upper half of the section. The main component, unblocked in the high-temperature range (commonly 610,680 °C) and believed to reside in haematite, presumably of mostly detrital origin, represents a characteristic remanence (ChRM). The tilt-corrected ChRM directions at individual sites show antipodal clusters (ratio of normal- to reverse-polarity sites: 0.62), and yield mean inclinations recording significant inclination shallowing,a feature well recorded in the Siwaliks. This ChRM is interpreted to represent a largely primary detrital remanence. The ChRM data from 430 sites yield the Karnali River magnetic polarity sequence, whose correlation with the geomagnetic polarity timescale (Cande & Kent 1995) suggests a depositional age of 16 Ma (younger than chron C5Cn.1n) to 5.2 Ma (around the top of chron C3r) for the 3560 m section sampled. Hence, the Karnali River exposes the oldest part of the Siwalik Group in Nepal. Estimates of the sediment accumulation rate (SAR) average to 32.9 cm kyr,1 for the 10.8 Myr time span of deposition. [source] Convergence acceleration by self-adjusted time stepsize using Bi-CGSTAB method for turbulent separated flow computationINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN FLUIDS, Issue 2 2002W. B. Tsai Abstract Poor convergence behavior is usually encountered when numerical computations on turbulent separated flow are performed. A design of self-adjusted stepsize concept both in time span and spatial coordinate systems to achieve faster convergence is demonstrated in this study. The determination of the time stepsize based on the concept of minimization of residuals using the Bi-CGSTAB algorithm is proposed. The numerical results show that the time stepsize adjusted by the proposed method indeed improves the convergence rate for turbulent separated flow computations using advanced turbulence models in low-Reynolds number forms. Copyright © 2002 John Wiley & Sons, Ltd. [source] Hypothesis: exposure to endocrine-disrupting chemicals may interfere with timing of pubertyINTERNATIONAL JOURNAL OF ANDROLOGY, Issue 2 2010A. Mouritsen Summary A recent decline in onset of puberty , especially among girls , has been observed, first in the US in the mid-1990s and now also in Europe. The development of breast tissue in girls occurs at a much younger age and the incidence of precocious puberty (PP) is increasing. Genetic factors and increasing prevalence of adiposity may contribute, but environmental factors are also likely to be involved. In particular, the widespread presence of endocrine-disrupting chemicals (EDCs) is suspected to contribute to the trend of earlier pubertal onset. The factors regulating the physiological onset of normal puberty are poorly understood. This hampers investigation of the possible role of environmental influences. There are many types of EDCs. One chemical may have more than one mode of action and the effects may depend on dose and duration of the exposure, as well as the developmental stage of the exposed individual. There may also be a wide range of genetic susceptibility to EDCs. Human exposure scenarios are complex and our knowledge about effects of mixtures of EDCs is limited. Importantly, the consequences of an exposure may not be apparent at the actual time of exposure, but may manifest later in life. Most known EDCs have oestrogenic and/or anti-androgenic actions and only few have androgenic or anti-oestrogenic effects. Thus, it appears plausible that they interfere with normal onset of puberty. The age at menarche has only declined by a few months whereas the age at breast development has declined by 1 year; thus, the time span from initiation of breast development to menarche has increased. This may indicate an oestrogen-like effect without concomitant central activation of the hypothalamic,pituitary axis. The effects may differ between boys and girls, as there are sex differences in age at onset of puberty, hormonal profiles and prevalence of precocius puberty. [source] Exploring the predictability of the ,Short Rains' at the coast of East AfricaINTERNATIONAL JOURNAL OF CLIMATOLOGY, Issue 11 2004Stefan Hastenrath Abstract The boreal autumn ,Short Rains' at the coast of East Africa are deficient when there is weak development of a zonal circulation cell along the Indian Ocean equator, an anomalously low sea-surface temperature in the western portion of the basin, and in the high phase of the southern oscillation. Such large-scale circulation departures and their precursors are described by compact indices. September values of these indices for the period 1958,96 are used to explore the predictability of an index (RON) of October,November rainfall at the coast of East Africa. Regressions with cross-validation over the entire 1958,96 period are evaluated for the early (1958,77) and late (1978,96) halves of the record. In complementary experiments, the entire record is separated into 1958,77 as a training period and 1978,96 as a verification period. In all experiments, correlation of calculated versus observed rainfall is high for the early record and low for the late half of the record, a behaviour not noted in cross-validation over the entire 39 year time span. The 11-year sliding correlations of the indicated circulation indices with RON all reveal a drastic deterioration of relationships from the early to the late half of the record, although the equatorial zonal circulation cell appears to remain strong throughout. Copyright © 2004 Royal Meteorological Society [source] Quetiapine indication shift in the elderly: diagnosis and dosage in 208 psychogeriatric patients from 2000 to 2006INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, Issue 5 2007Lorenz Hilwerling Abstract Rationale Quetiapine was approved in Germany as an atypical antipsychotic for treatment of schizophrenia in 2000, followed by the approval as an antipsychotic for treatment of bipolar mania in 2003. The approval of quetiapine for treatment of bipolar depression is expected. We hypothesized that the psychogeriatric prescription pattern for quetiapine shifts from the psychotic to the affective spectrum. Methods Retrospectively we screened discharge reports of all geriatric inpatients of the psychiatric department of the Ruhr-University of Bochum in the period from January 2001 until March 2006 and identified 208 individual patients aged over 60 years, who had received quetiapine as final medication. Age, gender, daily drug dose, year of treatment and diagnosis (according to ICD-10) were recorded and analyzed. Results Over the six-year time span, the proportion of affective disorders (F3) as indication for quetiapine in the elderly increased, whereas the proportion of dementia (F0) as indication for quetiapine decreased significantly. The proportion of schizophrenic disorders (F2) treated with quetiapine did not change significantly. Discussion Since the decision of the German Federal Court in 2002 ,off label' use goes to the expenses of the prescriber. So the decrease of quetiapine in dementia is probably due to its ,off label' status in dementia. The psychogeriatric indication shift for quetiapine towards affective disorders could be the consequence of good clinical experiences with the drug and growing evidence for its antidepressant effect. Conclusion In addition to controlled pharmacological trials prospective clinical research is needed to evaluate the prescription attitudes of clinicians. Copyright © 2006 John Wiley & Sons, Ltd. [source] Two millennia of male stature development and population health and wealth in the Low CountriesINTERNATIONAL JOURNAL OF OSTEOARCHAEOLOGY, Issue 4 2005G. J. R. MaatArticle first published online: 5 AUG 200 Abstract This paper offers a review of shifts in average male stature and their relationship with health and wealth in the Low Countries from AD 50 to 1997. Twenty-one population samples were studied to cover the full time span. To make data compatible, so-called ,virtual statures' were used, i.e. the statures which adult males were supposed to have had at the end of their growth period, before they started shrinking by ageing. Original data were extracted from ,in situ measured statures', ,calculated statures' and ,corrected cadaveric statures'. If possible, maximum femoral lengths were also collected from the same population samples to check whether trends in stature development were in agreement with raw skeletal data. A long phase of stature decrease from ca. 176,cm to 166,cm, a so-called ,negative secular trend', was noticed from the Roman Period up to and including the first half of the 19th century. This was followed by a sharp and still ongoing increase in stature to 184,cm, a typical ,positive secular trend', from the second half of the 19th century to the present time. General shifts in stature and ,outliers' illustrative for the process are viewed in the context of socio-economic, demographic, health and nutritional factors. Copyright © 2005 John Wiley & Sons, Ltd. [source] Reciprocal distribution of two congeneric trees, Betula platyphylla var. japonica and Betula maximowicziana, in a landscape dominated by anthropogenic disturbances in northeastern JapanJOURNAL OF BIOGEOGRAPHY, Issue 12 2005Katsuhiro Osumi Abstract Aim, Information has been compiled on disturbance regimes and the life-history characteristics of Betula platyphylla var. japonica (Miq.) Hara and B. maximowicziana Regel to investigate the impact of humans on the present distribution patterns of these two congeneric tree species. Location, The study area is in the central region of the northern Kitakami Mountain Range, located in the northeast of Honshu Island, Japan. Methods, First, the present distributions of B. maximowicziana and B. platyphylla var. japonica were mapped at the landscape scale. To examine the factors affecting the distribution patterns, topographic features and past land use were taken into account. Second, life-history traits of both species were clarified at various growth stages either by fieldwork or through a literature search. Previous studies have provided some information on seed production, seed dispersal, seedling dynamics, sprouting, and growth. In the present study, field observations and experiments were conducted regarding seed-bank formation, size and age at reproduction, and the life span of canopy trees. Results,Betula platyphylla var. japonica and B. maximowicziana were spatially segregated in the studied landscape (14,000 ha). The distribution of each species was correlated more strongly with land use at the beginning of the twentieth century than with site environmental factors such as altitude or slope angle. Betula platyphylla var. japonica was distributed more frequently on former grasslands, whereas B. maximowicziana was almost exclusively limited to past old-growth forests. As typical pioneers, the two species showed similar life-history traits but differed in several critical points. Betula platyphylla var. japonica has a vigorous sprouting ability, which might increase its resistance to burning and logging, whereas B. maximowicziana forms a persistent seed bank in the soil, indicating an advantage in regenerating in disturbances found in forest communities. Other critical differences were detected in age-related characteristics such as minimum age of reproduction and life span. Main conclusions, The earlier reproductive maturity and the shorter life span of B. platyphylla var. japonica indicate a shorter population cycle than that for B. maximowicziana. The latter would be excluded from grasslands that were burned frequently, as a result of the longer time span before initial reproduction and its poor sprouting ability. In contrast, B. platyphylla var. japonica would be excluded from old-growth forests, where disturbance was infrequent, owing to its shorter life span and lack of a persistent seed bank. [source] Impact of the black rhinoceros (Diceros bicornis minor) on a local population of Euphorbia bothae in the Great Fish River Reserve, South AfricaAFRICAN JOURNAL OF ECOLOGY, Issue 4 2009Bodina L. Luske Abstract In the Great Fish River Reserve, South Africa, black rhinoceros (Diceros bicornis minor) feed extensively on a local population of Euphorbia bothae. Maintaining the endangered black rhinoceros and the protected E. bothae population are both conservation priorities of the reserve. Therefore, the sustainability of this plant,animal interaction was investigated by comparing population characteristics, browsing incidence and intensity within the reserve and in an adjacent exclosure without access to rhino. Fixed-point photographs showed that over a 2-month period 36.6% of 213 monitored plants were browsed, with an average biomass loss of 13%, and 1% were destroyed. Of 26 plants re-photographed after approximately 3 years, 70% showed a decrease in biomass, averaging 37.8% over this period. In this time span, 19% of the monitored plants died. Small plants (<45 cm) were over-represented in the rhino-browsed area, whereas the fraction of reproductively active plants and overall plant density were found to be lower than in the adjacent exclosure. No evidence of short-term compensatory growth in response to browsing was found for E. bothae. This study indicates that, with the current population size, rhinos are overexploiting the E. bothae population and special measures should be taken to prevent local extinction. Résumé Dans la Great Fish River Reserve, en Afrique du Sud, le rhinocéros noir (Diceros bicornis minor) se nourrit en très grande partie d'une population locale d'Euphorbia bothae. Le maintien du rhino noir en danger et de la population protégée d'E. bothae sont deux priorités de la réserve en matière de conservation. C'est pourquoi on a investigué la durabilité de cette interaction plante-animal en comparant les caractéristiques des populations, l'incidence et l'intensité de la consommation du rhino dans la réserve et dans un enclos adjacent d'où les rhinos sont exclus. Des photographies prises d'un point fixe ont montré que, sur une période de deux mois, 36.6% des 213 plantes suivies avaient été broutées, avec une perte moyenne de biomasse de 13%, et un pour cent avait été détruit. Des 26 plantes qui avaient été rephotographiées après environ trois ans, 70% montraient une diminution de la biomasse, qui était de 37.8% en moyenne pour cette période. Pendant ce laps de temps, 19% des plantes suivies sont mortes. Les petites plantes (<45 cm) étaient surreprésentées dans la zone broutée par les rhinos, alors que la fraction des plantes actives au point de vue reproduction et la densité générale des plantes se sont avérées plus faibles que dans l'enclos adjacent. On n'a pu mettre en évidence aucune croissance compensatoire d'E. bothaeà court terme en réponse au broutage des rhinos. Cette étude indique que, vu la taille actuelle de leur population, les rhinos surexploitent la population d'E. bothae et qu'il faut prendre des mesures spéciales pour empêcher l'extinction locale de cette dernière. [source] Short-term anti-plaque effect of two chlorhexidine varnishesJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 8 2005Jan Cosyn Abstract Background: Chlorhexidine (CHX) varnishes have been mainly used for the prevention of caries in high-risk populations. Reports regarding their anti-plaque effect on a clinical level are limited to non-existing as opposed to their microbiological impact on plaque formation. Aim: The aim of this preliminary investigation was to evaluate the anti-plaque effect of two CHX varnishes applied on sound enamel in relation to a positive control, a negative control and to one another. Methods: Sixteen healthy subjects volunteered for this randomized-controlled, single-blind, four-treatment,four-period crossover-designed clinical trial. A 3-day plaque re-growth model was used to determine de novo plaque accumulation following CHX rinsing, Cervitec® application, EC40® application and no therapy. The amount of plaque was measured using the Quigley and Hein plaque index and "automatic image analysis" (AIA). Results and Conclusions: Varnish treatment resulted in significantly higher plaque levels than CHX rinsing irrespective of the varnish that was used (p0.002), implying that the latter is likely to remain the gold standard as an anti-plaque agent. However, highly significant differences were also found in favour of both varnish systems when compared with no therapy (p<0.001), which indicates that varnish treatment is an effective means of inhibiting plaque formation in a short time span. Cervitec® exhibited slightly, yet significantly, higher plaque levels in comparison with EC40® as determined by AIA (p=0.006). Large-scale trials with a longer observation period are necessary to substantiate these results. [source] Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population-based studyAGING CELL, Issue 6 2005Carmen M. Martin-Ruiz Summary Cross-sectional studies have repeatedly suggested peripheral blood monocyte telomere length as a biomarker of aging. To test this suggestion in a large population-based follow-up study of the oldest old, we measured telomere length at baseline in 598 participants of the Leiden 85-plus Study (mean age at baseline 89.8 years). We also obtained second telomere measurements from 81 participants after an average time span of between 3.9 and 12.9 years. Telomere length at baseline was not predictive for mortality (P > 0.40 for all-cause, cardiovascular causes, cancer or infectious diseases, Cox regression for gender-adjusted tertiles of telomere length) or for the incidence of dementia (P = 0.78). Longitudinally, telomere length was highly unstable in a large fraction of participants. We conclude that blood monocyte telomere length is not a predictive indicator for age-related morbidity and mortality at ages over 85 years, possibly because of a high degree of telomere length instability in this group. [source] Export market participation, spillovers, and foreign direct investment in Australian food manufacturingAGRIBUSINESS : AN INTERNATIONAL JOURNAL, Issue 3 2010Shauna Phillips Generating a more outward looking sector has been one of the principal aims of agrifood policy in Australia for the past two decades. Australia's proximity to fast-growing economies of East Asia has been seen as a major source for export growth. Over the same time span, there has been an increase in foreign ownership in the food sector. Using a firm-level data set for 2005, we characterize the probability that a firm participates in exporting by a set of firm characteristics, including foreign ownership and spillovers from foreign-owned firms, and find that foreign ownership neither increases nor decreases the probability that a firm will be involved in exporting. [EconLit citations: Q170, Q130]. © 2010 Wiley Periodicals, Inc. [source] Head structures of males of Strepsiptera (Hexapoda) with emphasis on basal splitting events within the orderJOURNAL OF MORPHOLOGY, Issue 5 2006Rolf Georg Beutel Abstract Internal and external head structures of males of Strepsiptera were examined and the head of a species of Mengenilla is described in detail. The results suggest a reinterpretation of some structures. The head of basal extant strepsipterans is subprognathous, whereas it is strictly orthognathous in the groundplan of Strepsiptera s.l. The labrum and hypopharynx are not part of the mouthfield sclerite. The labial palps are absent in all strepsipterans. A very slightly modified mandibular articulation is preserved in Eoxenos, whereas it is distinctly reduced in other extant groups. A salivary duct, salivary glands, and a cephalic aorta are absent. The cladistic analysis of 44 characters of the head results in the following branching pattern: (Protoxenos + (Mengea + (Eoxenos + (Mengenilla [Austr.] + Mengenilla) + (Elenchus + Dundoxenos + Xenos + Stylops)))). Most apomorphies of males are associated with the necessity of finding females within a short time span and with a reduced necessity to consume food: large "raspberry" eyes, flabellate antennae with numerous dome-shaped chemoreceptors, Hofeneder's organ, an ovoid sensillum of the maxillary palp, and the simplified condition of the maxilla and the labium. Strepsiptera excl. Protoxenos are supported by the dorsomedian frontal impression, the dorsally shifted antennal insertions, a reduced number of antennal segments, absence of the galea, and probably by the presence of the mouthfield sclerite, which is a unique apomorphic feature. The balloon-gut combined with an unusual air-uptake apparatus is another possible autapomorphy of this clade. It is likely that the last common ancestor of Strepsiptera excl. Protoxenos did not process food. Strepsiptera s.str. are characterized by the strongly reduced condition of the labrum and the absence of the epistomal suture. Eoxenos is the sister group of the remaining Strepsiptera s.str. Synapomorphies of Mengenilla + Stylopidia are the advanced reduction of the mandibular articulation and the secondary absence of the ovoid sensillum. The monophyly of Mengenilla is confirmed, even though a small free labrum is present in Australian species. Derived features of Stylopidia are the absence of the coronal suture and the reduced condition of the frontal suture. Apomorphies that have evolved within Stylopidia are the membranization of parts of the head, the fusion of antennal segments, the increase or decrease of the number of flabellate flagellomeres, reductions and modifications of the mandibles, and modifications of the mouthfield sclerite. The monophyly of Stylopiformia is not unambiguously supported. A position of the mandibles posterior to the mouthfield sclerite (when adducted) is a possible synapomorphy shared by Xenos, Stylops, and other "higher Stylopidia." The blade-like distal part of the mandibles suggests a closer relationship of Elenchus with these taxa. © 2004 Wiley-Liss, Inc. [source] The Effect of a Constant Electrical Field on Osseointegration after Immediate Implantation in Dog Mandibles: A Preliminary StudyJOURNAL OF PROSTHODONTICS, Issue 5 2007Yadollah Soleymani Shayesteh DDS Purpose: The long time span between insertion of implants and functional rehabilitation often inconveniences patients. Accelerating bone growth around dental implants can shorten this time span. This in vivo study evaluated the effect of a constant electrical field on bone growth around dental implants. Materials and Methods: Four mongrel dogs were used in this study. Sixteen dental implants were placed immediately after extraction of the first premolar and molar teeth. A constant electrical field (CEF) generator was placed in the mucoperiostal pouch created from the subperiostral dissection under the inferior border of the dog's mandible and connected to the experiment side fixtures. CEF provided 3 V of electrical potential during osseointegration. Histologic sections were stained with hematoxylin,eosin and observed under light microscopy. The sections were analyzed histomorphometrically to calculate the amount of newly formed bone. Statistical analysis was performed with SPSS 11.0 computer software (,= 0.05). Results: At the end of the first stage of the osseointegration (90 days) CEF group sections showed enhanced growth of the trabeculae compared with the control group. Statistical analysis revealed significant differences between experimental and control groups. Bone contact ratio was statistically significant in the experimental group (p= 0.001). An increase in the local bone formation and bone contact ratio was observed with direct electrical stimulation of the implant and the bone area around the implant. Conclusion: Minimal direct electrical current, which can produce an electrical field around the implant, can increase the amount of bone formation and decrease the time of osseointegration. [source] Detection of Recent Ethanol Intake With New Markers: Comparison of Fatty Acid Ethyl Esters in Serum and of Ethyl Glucuronide and the Ratio of 5-Hydroxytryptophol to 5-Hydroxyindole Acetic Acid in UrineALCOHOLISM, Issue 5 2005K Borucki Background: At present, recent ethanol consumption can be routinely detected with certainty only by direct measurement of ethanol concentration in blood or urine. Because ethanol is rapidly eliminated from the circulation, however, the time span for this detection is in the range of hours. Several new markers have been proposed to extend the detection interval, but their characteristics have not yet justified their use in routine clinical practice. We therefore investigated three new markers and compared their kinetics and sensitivities: (1) fatty acid ethyl esters (FAEEs) in serum, (2) ethyl glucuronide (EtG) in urine, and (3) the ratio of 5-hydroxytryptophol to 5-hydroxyindole acetic acid (5-HTOL/5-HIAA) in urine. Methods: Seventeen healthy men participated in a drinking experiment. Blood and urine samples were collected twice daily on three consecutive days and once daily on days 4 and 5. Ethanol concentration was determined by gas chromatography, FAEE levels, by gas chromatography with mass spectrometry, EtG concentration, by liquid chromatography-tandem mass spectrometry, and 5-HTOL/5-HIAA ratio, by high-performance liquid chromatography. Results: The peak serum ethanol concentrations of the subjects ranged from 5.4 to 44.7 mmol/liter (mean ± SD, 30.1 ± 9.1 mmol/liter). In the case of the serum ethanol determination, 100% sensitivity was reached only immediately after the end of the drinking experiment, and in the case of FAEE levels and 5-HTOL/5-HIAA ratio, it tested for 6.7 hr after the end of the ethanol intake. Thereafter, these latter parameters declined until 15.3 hr (FAEEs) and 29.4 hr (5-HTOL/5-HIAA), subsequently remaining in a stable range until 78.5 hr without further decrease. In contrast, EtG concentration showed 100% sensitivity until 39.3 hr and thereafter decreased, falling to below the limit of quantification of 0.1 mg/liter at 102.5 hr. Conclusion: After moderate drinking, EtG in the urine proved to be a superior marker of recent ethanol consumption in healthy subjects. This is because EtG is a direct ethanol metabolite, it occurs in the urine only when ethanol has been consumed, and its sensitivity remains at the level of 100% for 39.3 hr. [source] Recommending change clusters to support software investigation: an empirical studyJOURNAL OF SOFTWARE MAINTENANCE AND EVOLUTION: RESEARCH AND PRACTICE, Issue 3 2010Martin P. Robillard Abstract During software maintenance tasks, developers often spend a valuable amount of effort investigating source code. This effort can be reduced if tools are available to help developers navigate the source code effectively. We studied to what extent developers can benefit from information contained in clusters of change sets to guide their investigation of a software system. We defined change clusters as groups of change sets that have a certain amount of elements in common. Our analysis of 4200 change sets for seven different systems and covering a cumulative time span of over 17 years of development showed that less than one in five tasks overlapped with change clusters. Furthermore, a detailed qualitative analysis of the results revealed that only 13% of the clusters associated with applicable change tasks were likely to be useful. We conclude that change clusters can only support a minority of change tasks, and should only be recommended if it is possible to do so at minimal cost to the developers. Copyright © 2009 John Wiley & Sons, Ltd. [source] Applying centrality measures to impact analysis: A coauthorship network analysisJOURNAL OF THE AMERICAN SOCIETY FOR INFORMATION SCIENCE AND TECHNOLOGY, Issue 10 2009Erjia Yan Many studies on coauthorship networks focus on network topology and network statistical mechanics. This article takes a different approach by studying micro-level network properties with the aim of applying centrality measures to impact analysis. Using coauthorship data from 16 journals in the field of library and information science (LIS) with a time span of 20 years (1988,2007), we construct an evolving coauthorship network and calculate four centrality measures (closeness centrality, betweenness centrality, degree centrality, and PageRank) for authors in this network. We find that the four centrality measures are significantly correlated with citation counts. We also discuss the usability of centrality measures in author ranking and suggest that centrality measures can be useful indicators for impact analysis. [source] Vegetation, environment, and time: The origination and termination of ecosystemsJOURNAL OF VEGETATION SCIENCE, Issue 5 2006Stephen T. Jackson Abstract Terrestrial ecosystems originate when particular plant species attain dominance at specific locations under specific environmental regimes. Ecosystems terminate, gradually or abruptly, when the dominant species or functional types are replaced by others, usually owing to environmental change or severe and irreversible disturbance. Assessing whether current ecosystems are sustainable in the face of future environmental change can be aided by examining the range of environmental variation those ecosystems have experienced in the past, and by determining the environmental conditions under which those ecosystems arose. The range of environmental variation depends on the time scale at which it is assessed. A narrow time span (e.g. 200,300 years) may underestimate the range of variation within which an ecosystem is sustainable, and it may also underestimate the risk of major transformation or disruption of that ecosystem by environmental change. Longer time spans (e.g. 1000,2000 years) increase the range of variation, by encompassing a larger sample of natural variability as well as non-stationary variability in the earth system. Most modern ecosystems disappear when the time span is expanded to 10000,15 000 years owing to secular changes in earth's climate system. Paleo-ecological records can pinpoint the time of origination of specific ecosystems, and paleo-environmental records can reveal the specific environmental changes that led to development of those ecosystems and the range of environmental variation under which those ecosystems have maintained themselves in the past. This information can help identify critical environmental thresholds beyond which specific modern ecosystems can no longer be sustained. [source] HCV-specific T-cell responses in injecting drug users: evidence for previous exposure to HCV and a role for CD4+ T cells focussing on nonstructural proteins in viral clearanceJOURNAL OF VIRAL HEPATITIS, Issue 6 2008T. A. Ruys Summary., In order to understand the parameters associated with resolved hepatitis C virus (HCV)-infection, we analysed the HCV-specific T-cell responses longitudinally in 13 injecting drug-users (IDUs) with a prospectively identified acute HCV infection. Seven IDUs cleared HCV and six IDUs remained chronically infected. T-cell responses were followed in the period needed to resolve and a comparable time span in chronic carriers. Ex vivo T-cell responses were measured using interferon-, Elispot assays after stimulation with overlapping peptide pools spanning the complete HCV genome. CD4+ memory- T-cell responses were determined after 12-day stimulation with HCV proteins. The maximum response was compared between individuals. The T-cell responses measured directly ex vivo were weak but significantly higher in resolvers compared to chronic carriers, whereas the CD4+ memory -T-cell response was not different between resolvers and chronic carriers. However, HCV Core protein was targeted more often in chronic carriers compared to individuals resolving HCV infection. CD4+ T-cell responses predominantly targeting nonstructural proteins were associated with resolved HCV infection. Interestingly, observation of memory-T-cell responses present before the documented HCV-seroconversion suggests that reinfections in IDUs occur often. The presence of these responses however, were not predictive for the outcome of infection. However, a transition of the HCV-specific CD4+ memory -T-cell response from targeting Core to targeting nonstructural proteins during onset of infection was associated with a favourable outcome. Therefore, the specificity of the CD4+ memory -T-cell responses measured after 12-day expansion seems most predictive of resolved infection. [source] Subclinical reactivation of herpes simplex virus type 1 in the oral cavityMOLECULAR ORAL MICROBIOLOGY, Issue 5 2000B. Knaup Reactivation in the oral cavity either symptomatically (recrudescence) or without symptoms (recurrence) may contribute to the transmission of herpes simplex virus type 1 (HSV-1), especially in critical areas of exposure such as dentistry. In order to measure the frequency of HSV-1 reactivation, nested polymerase chain reaction (PCR) was performed on oral swabs collected from 30 healthy people over a period of 58,161 days. In total 19 of 25 (76%) seropositive people were PCR-positive at least once, 6 of these 19 (32%) had recrudescence and 13 (68%) had only asymptomatic reactivation. Frequencies of additional recurrences were higher in people showing symptomatic reactivation than in those who had only recurrences. Recrudescence is a risk factor for elevated levels of asymptomatic HSV-shedding. In most cases HSV-1 was detected only by nested PCR investigated by early onset of therapy or time span before sampling. [source] Convergence acceleration by varying time-step size using Bi-CGSTAB method for turbulent flow computationNUMERICAL METHODS FOR PARTIAL DIFFERENTIAL EQUATIONS, Issue 5 2001W. B. Tsai Abstract A design of varying step size approach both in time span and spatial coordinate systems to achieve fast convergence is demonstrated in this study. This method is based on the concept of minimization of residuals by the Bi-CGSTAB algorithm, so that the convergence can be enforced by varying the time-step size. The numerical results show that the time-step size determined by the proposed method improves the convergence rate for turbulent computations using advanced turbulence models in low Reynolds-number form, and the degree of improvement increases with the degree of the complexity of the turbulence models. © 2001 John Wiley & Sons, Inc. Numer Methods Partial Differential Eq 17: 454,474, 2001. [source] |