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Temporary Loss (temporary + loss)

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Medical Sciences	100%

Selected Abstracts

A new type of susceptibility-artefact-based magnetic resonance angiography: intra-arterial injection of superparamagnetic iron oxide particles (SPIO) A Resovist® in combination with TrueFisp imaging: a feasibility study

CONTRAST MEDIA & MOLECULAR IMAGING, Issue 5 2006
Robbert M. Maes
Abstract The goal of this study was to evaluate the use of super paramagnetic particles of iron oxide (SPIO) as a dark blood contrast agent, in combination with a bright blood steady-state free precession sequence for magnetic resonance angiography (MRA), in an animal model. The original concentration of the SPIO of 500,mmol Fe/l and dilutions to 250, 125, 60, 30, 10 and 5,mmol Fe/l were intra-arterially injected into the aorta of a pig. Then the dilution of 10,mmol Fe/l was chosen for repeated intra-arterial injections into two pigs. During these intra-arterial SPIO injections MR images were acquired with a 1.5,T scanner. Signal intensity measurements were performed in the aorta. The signal-to-noise ratio during SPIO bolus passage was significantly less than during baseline conditions (Fisher's F -ratio 159.8, p,<,0.005) or the recovery signal-to-noise ratio (Fisher's F -ratio 144.6, p,<,0.005). Also, confirmation of flow distal to the catheter-tip position was possible. The use of SPIO as a dark blood agent in combination with a bright blood MR imaging sequence is feasible. Temporary loss of intraluminal signal occurs due to local decrease of the signal because of induction of local inhomogeneities after mixture the present blood and SPIO solution. It provides immediate information about blood flow distal to the catheter and is a potentially useful to guide intravascular MR-interventional procedures. Copyright © 2006 John Wiley & Sons Ltd. [source]

Temporary hair removal by low fluence photoepilation: Histological study on biopsies and cultured human hair follicles

LASERS IN SURGERY AND MEDICINE, Issue 8 2008
Guido F. Roosen MSc
Abstract Background and Objectives We have recently shown that repeated low fluence photoepilation (LFP) with intense pulsed light (IPL) leads to effective hair removal, which is fully reversible. Contrary to permanent hair removal treatments, LFP does not induce severe damage to the hair follicle. The purpose of the current study is to investigate the impact of LFP on the structure and the physiology of the hair follicle. Study Design/Materials and Methods Single pulses of IPL with a fluence of 9 J/cm2 and duration of 15 milliseconds were applied to one lower leg of 12 female subjects, followed by taking a single biopsy per person, either immediately, or after 3 or 7 days. Additionally, we present a novel approach to examine the effects of LFP, in which ex vivo hairy human scalp skin was exposed to IPL pulses with the same parameters as above, followed by isolation and culturing of the hair follicles over several days. Samples were examined histologically and morphologically. Results The majority of the cultured follicles that had been exposed to LFP treatment showed a marked treatment effect. The melanin containing part of the hair follicle bulb was the target and a catagen-like transformation was observed demonstrating that hair formation had ceased. The other follicles that had been exposed to LFP showed a less strong or no response. The skin biopsies also revealed that the melanin-rich region of the hair follicle bulb matrix was targeted; other parts of the follicle and the skin remained unaffected. Catagen/telogen hair follicles were visible with unusual melanin clumping, indicating this cycle phase was induced by the IPL treatment. Conclusions Low fluence photoepilation targets the pigmented matrix area of the anagen hair follicle bulb, causing a highly localized but mild trauma that interrupts the hair cycle, induces a catagen-like state and eventually leads to temporary loss of the hair. Lesers Surg. Med. 40:520,528, 2008. © 2008 Wiley-Liss, Inc. [source]

1224: Psychological preparation for the ophthalmic operation, suggestive techniques guiding the patient during the procedures

ACTA OPHTHALMOLOGICA, Issue 2010
E JAKUBOVICS
Purpose An illness, pain, an emotionally demanding situation (e.g. an injury, being frightened) are associated with certain conditions of the psyche, in which suggestions have strong effects on people. During the operation the patient's thoughts focus on their conditions and the challenges ahead. The fear of pain, temporary loss of usual references, being placed in helpless positions, the light from the microscope, the surgical drapes (which excluded the environmental stimuli), being confronted by alarming machines and seemingly incomprehensible actions of hospital staff, brings the spontaneously altered state of mind. Our working hypothesis was that if the patients are psychologically well prepared before the operation and if this is followed by positive verbal suggestions during the procedure, their pain relief requirement will be less and their condition will improve faster. Methods We developed a specific verbal suggestion protocol for the patients and observed the patients' psychological and physiological state in the perioperative period. Results The protocol worked well in reducing patients' fear and improved their satisfaction. This protocol is easy for doctors and staff to learn. Based on the literature and our studies, younger people are more susceptible. Conclusion Except the excellent painless surgical technique, the comfortable environment, the psychological drive of patients around the procedure has a robust factor to improve the patients satisfactory. [source]

Enuresis in hyperthyroidism: a temporary lack of central control mechanism leads to nocturnal enuresis

ACTA PAEDIATRICA, Issue 1 2010
J Meir
Abstract We report on a 9-year-old boy who suffered from hyperthyroidism and a new appearance of enuresis. Bedwetting ceased and prepulse inhibition (PPI) , measured as a parameter of central control , increased during the course of therapy. Conclusion:, The increase in PPI is an indication that enuresis in hyperthyroidism could be as a result of a temporary loss of central control on brainstem reflexes. The case conveys new insights into the correlation between thyroid hormones and micturition patterns and the aetiology of enuresis. [source]