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tert-Butyl Hydroperoxide (tert-butyl + hydroperoxide)
Selected AbstractsChemInform Abstract: Indium(III) Chloride Catalyzed Oxidative Cleavage of Carbon,Carbon Multiple Bonds by tert-Butyl Hydroperoxide in Water , A Safe Alternative to Ozonolysis.CHEMINFORM, Issue 31 2008Brindaban C. Ranu Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: CuCl Catalyzed Selective Oxidation of Primary Alcohols to Carboxylic Acids with tert-Butyl Hydroperoxide at Room Temperature.CHEMINFORM, Issue 30 2008Sreedevi Mannam Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Oxidation of Anisoles to p-Benzoquinone Monoketals Catalyzed by a Ruthenium Complex of 1,4,7-Trimethyl-1,4,7-triazacyclononane with tert-Butyl Hydroperoxide.CHEMINFORM, Issue 10 2006Wai-Hung Cheung Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Photochemical Oxidation of 1,3-Dithianes with tert-Butyl Hydroperoxide (TBHP).CHEMINFORM, Issue 43 2004M. H. Habibi Abstract For Abstract see ChemInform Abstract in Full Text. [source] A Silica Gel Supported Ruthenium Complex of 1,4,7-Trimethyl-1,4,7-triazacyclononane as Recyclable Catalyst for Chemoselective Oxidation of Alcohols and Alkenes by tert-Butyl Hydroperoxide.CHEMINFORM, Issue 14 2003Wai-Hung Cheung Abstract For Abstract see ChemInform Abstract in Full Text. [source] Identification of distinct and common gene expression changes after oxidative stress and gamma and ultraviolet radiation,MOLECULAR CARCINOGENESIS, Issue 2 2003Alexandra N. Heinloth Abstract The human genome is exposed to many different kinds of DNA-damaging agents. While most damage is detected and repaired through complex damage recognition and repair machineries, some damage has the potential to escape these mechanisms. Unrepaired DNA damage can give rise to alterations and mutations in the genome in an individual cell, which can result in malignant transformation, especially when critical genes are deregulated. In this study, we investigated gene expression changes in response to oxidative stress, gamma (,) radiation, and ultraviolet (UV) radiation and their potential implications in cancer development. Doses were selected for each of the three treatments, based on their ability to cause a similar G1 checkpoint induction and slow down in early S-phase progression, as reflected by a comparable reduction in cyclin E,associated kinase activity of at least 75% in logarithmically growing human dermal diploid fibroblasts. To investigate gene expression changes, logarithmically growing dermal diploid fibroblasts were exposed to either , radiation (5 Gy), oxidative stress (75 ,M of tert-butyl hydroperoxide (t -butyl-OOH)), or UV radiation (UVC) (7.5 J/m2) and RNA was harvested 6 h after treatment. Gene expression was analyzed using the NIEHS Human ToxChip 2.0 with approximately 1901 cDNA clones representing known genes and expressed sequence tags (ESTs). We were able to identify common and distinct responses in dermal diploid fibroblasts to the three different stimuli used. Within our analysis, gene expression profiles in response to , radiation and oxidative stress appeared to be more similar than profiles expressed after UV radiation. Interestingly, equivalent cyclin E,associated kinase activity reduction with all the three treatments was associated with greater transcriptional changes after UV radiation than after , radiation and oxidative stress. While samples treated with UV radiation displayed modulations of their mitogen activated protein kinase (MAPK) pathway, , radiation had its major influence on cell-cycle progression in S-phase and mitosis. In addition, cell cultures from different individuals displayed significant differences in their gene expression responses to DNA damage. Published 2003 Wiley-Liss, Inc. [source] Functional analysis and expression characteristics of chloroplastic Prx IIEPHYSIOLOGIA PLANTARUM, Issue 3 2008Filipe Gama Peroxiredoxins (Prxs) are ubiquitous thiol-dependent peroxidases capable of eliminating a variety of peroxides through reactive catalytic cysteines, which are regenerated by reducing systems. Based on amino acid sequences and their mode of catalysis, five groups of thiol peroxidases have been distinguished in plants, and type II Prx is one of them with representatives in many sub-cellular compartments. The mature form of poplar chloroplastic Prx IIE was expressed as a recombinant protein in Escherichia coli. The protein is able to reduce H2O2 and tert-butyl hydroperoxide and is regenerated by both glutaredoxin (Grx) and thioredoxin (Trx) systems. Nevertheless, compared with Trxs, Grxs, and more especially chloroplastic Grx S12, are far more efficient reductants towards Prx IIE. The expression of Prx IIE at both the mRNA and protein levels as a function of organ type and abiotic stress conditions was investigated. Western blot analysis revealed that Prx IIE gene is constitutively expressed in Arabidopsis thaliana, mostly in young and mature leaves and in flowers. Under photo-oxidative treatment and water deficit, almost no change was observed in the abundance of Prx IIE in A. thaliana, while the level of Prx Q (one of the two other chloroplastic Prxs with 2-Cys Prx) increased in response to both stresses, indicating that plastidic members of the Prx family exhibit specific patterns of expression under stress. [source] High temperature does not alter fatigability in intact mouse skeletal muscle fibresTHE JOURNAL OF PHYSIOLOGY, Issue 19 2009Nicolas Place Intense activation of skeletal muscle results in fatigue development, which involves impaired function of the muscle cells resulting in weaker and slower contractions. Intense muscle activity also results in increased heat production and muscle temperature may rise by up to ,6°C. Hyperthermia is associated with impaired exercise performance in vivo and recent studies have shown contractile dysfunction and premature fatigue development in easily fatigued muscle fibres stimulated at high temperatures and these defects were attributed to oxidative stress. Here we studied whether fatigue-resistant soleus fibres stimulated at increased temperature show premature fatigue development and whether increasing the level of oxidative stress accelerates fatigue development. Intact single fibres or small bundles of soleus fibres were fatigued by 600 ms tetani given at 2 s intervals at 37°C and 43°C, which is the highest temperature the muscle would experience in vivo. Tetanic force in the unfatigued state was not significantly different at the two temperatures. With 100 fatiguing tetani, force decreased by ,15% at both temperatures; the free cytosolic [Ca2+] (assessed with indo-1) showed a similar ,10% decrease at both temperatures. The oxidative stress during fatigue at 43°C was increased by application of 10 ,m hydrogen peroxide or tert-butyl hydroperoxide and this did not cause premature fatigue development. In summary, fatigue-resistant muscle fibres do not display impaired contractility and fatigue resistance at the highest temperature that mammals, including humans, would experience in vivo. Thus, intrinsic defects in fatigue-resistant muscle fibres cannot explain the decreased physical performance at high temperatures. [source] | ||||||||||