Home  About us  Contact
 

Systemic Retinoids (systemic + retinoid)

Distribution by Scientific Domains
Medical Sciences100%

Selected Abstracts

Retinoids and Wound Healing

DERMATOLOGIC SURGERY, Issue 10 2006
MARK ABDELMALEK MD
BACKGROUND Retinoids are widely used in dermatology and may play a role in wound healing. The exact role of retinoids in wounds is confusing and controversial, however. Systemic retinoids are presumed to be detrimental to wound healing; however, this standard is based on isolated reports. OBJECTIVE The objective was to provide a critical review of the available literature regarding the role of both topical and systemic retinoids in various aspects of wound healing. CONCLUSIONS Pretreatment with retinoids likely promotes wound healing after facial resurfacing procedures and full- or partial-thickness wounds. While the evidence is mixed regarding the effects of retinoids applied to fresh and healing wounds, the majority of the evidence available shows favorable wound-healing properties in this setting. The medical,legal standard regarding the avoidance of facial resurfacing and surgical procedures in patients on or recently completing a course of systemic retinoids was likely prematurely established. [source]

Palmoplantar Keratoderma and Skin Grafting: Postsurgical Long-term Follow-up of Two Cases with Olmsted Syndrome

PEDIATRIC DERMATOLOGY, Issue 2 2008
Marie-Sophie Bédard M.D.
Treatment options include topical keratolytics, systemic retinoids, and debulking procedures. Full-thickness excision of hyperkeratotic plaques followed by skin grafting has been reported in the medical literature, although long-term results have not been evaluated. We present two cases of Olmsted syndrome with severe palmoplantar keratoderma treated with excision and skin grafting, along with long-term clinical results 11 years (patient 1) and 6 years (patient 2) following the initial surgery. [source]

Acitretin induced bipedal edema

THE JOURNAL OF DERMATOLOGY, Issue 5 2006
Hong Liang TEY
ABSTRACT Generalized edema has been reported to be a rare side effect of systemic retinoids. We report a patient who developed localized bipedal edema from acitretin. Other causes of bipedal edema were excluded and withdrawal of acitretin led to resolution of the edema. [source]