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Synthetic Transformations (synthetic + transformation)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

ChemInform Abstract: A Simple and Efficient Strategy Towards Eleven-Membered Carbocycles via Novel Synthetic Transformations of Pentafulvenes.

CHEMINFORM, Issue 17 2008
K. Syam Krishnan
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Synthetic Transformations of Higher Terpenoids.

CHEMINFORM, Issue 27 2003
Part 8. [4 + 2]-Cycloaddition Reactions of Lambertianic Acid.
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

The Development of Enantioselective Rhodium-Catalysed Hydroboration of Olefins

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 5 2005
Anne-Marie Carroll
Abstract Rhodium-catalysed enantioselective hydroboration of olefins is a valuable synthetic transformation, typically employing a chiral catalyst and an achiral borane source. The pertinent chemo-, regio- and enantioselectivity issues of this reaction are discussed. However, the main emphasis of this review is on the evolution of catalytic asymmetric hydroboration. This has primarily relied upon the development and application of chiral bidentate P,P and P,N ligands which have exhibited varying degrees of success in this transformation. [source]

Diversity-Oriented Approach to Biologically Relevant Molecular Frameworks Starting with ,-Naphthol and Using the Claisen Rearrangement and Olefin Metathesis as Key Steps

CHEMISTRY - A EUROPEAN JOURNAL, Issue 31 2006
Sambasivarao Kotha Prof. Dr.
Abstract A diversity-oriented approach for the synthesis of various structurally different molecular frameworks from readily accessible and common precursors is described. A Claisen rearrangement followed by ring-closing metathesis or ethylene-promoted ring-closing enyne metathesis has been utilized as the key synthetic transformation to generate naphthoxepine derivatives. The ring-closing metathesis approach has also been used to generate spirocyclic compounds and the pleiadene framework. [source]

Broadening the Synthetic Scope of the Iron(III)-Catalyzed Aza-Prins Cyclization

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 12 2010
Rubén M. Carballo
Abstract The nature and influence of the N -sulfonyl group in aza-Prins cyclization and the reactivity of the six-membered aza-cycle generated has been studied. The aza-Prins cyclization of ,,,-unsaturated amines with a tosyl group at the nitrogen atom produces 2-alkyl-4-halo-1-tosyl-1,2,5,6-tetrahydropyridines with a halovinyl function, extraordinarily stable to further derivatization and detosylation conditions. To modulate the reactivity of such aza-cycles, a general study of the aza-Prins cyclization reaction was performed with several sulfonamides. Ring formation occurs satisfactorily with both N -nosyl and N -mesylamines providing optimal conditions for further synthetic transformations. To exemplify the scope of this methodology, a short synthesis of the alkaloid coniine was successfully carried out. [source]

Three-Component Synthesis of Highly Functionalized 5-Acetyloxazoles

CHEMISTRY - A EUROPEAN JOURNAL, Issue 22 2009
Tilman Lechel
Abstract By a flexible three-component synthesis, alkoxy-substituted enamides are easily available from lithiated alkoxyallenes, nitriles and carboxylic acids (see scheme). The treatment of these versatile intermediates with trifluoroacetic acid provided 5-acetyloxazoles in moderate to good yields. Different substituents are possible at C-2 and C-5 and the 5-acetyl group is a suitable handle for further synthetic transformations. [source]