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Subjects' Perception (subject + perception)
Selected AbstractsThe Impact of Treatment Intervention on Parenting Stress in Postpartum Depressed Mothers: A Prospective StudyAMERICAN JOURNAL OF ORTHOPSYCHIATRY, Issue 1 2006FRCPC, Shaila Misri MD The aim of this study was to evaluate whether treatment intervention for postpartum depression impacted maternal parenting stress levels. Twenty,three mothers referred for postpartum mood and anxiety disorder to an outpatient program were included in the study. Statistically and clinically significant decreases in levels of parenting stress were evident at the end of the treatment. Subjects' perceptions of their parenting characteristics were found to be a major contributor to stress levels. In addition to monitoring of depressive symptoms, routine assessment of maternal parenting qualities is recommended to ensure healthy child outcomes. [source] The use of light-emitting diode therapy in the treatment of photoaged skinJOURNAL OF COSMETIC DERMATOLOGY, Issue 3 2007FACCS, FRACGP, Fabien Baez MBBS, MAACS, MCPSA Summary Background, Light-emitting diode (LED) therapy is an increasingly popular methodology for the treatment of sun damage. Combination use of light wavelengths reported to stimulate collagen synthesis and accelerate fibroblast,myofibroblast transformation may display a composite rejuvenative effect. Objective, To clinically assess reduction in sun damage signs following a 5-week course of LED therapy and to assess subject's perception of the treatment. Methods, Thirteen subjects with wrinkles or fine lines in the periorbital and nasolabial region and those presenting Glogau scale photodamage grade II,III received nine 20-min duration light treatments using the OmniluxÔ LED system. The treatments combined wavelengths of 633 and 830 nm at fluences of 126 and 66 J/cm2, respectively. Sun-damage reduction was assessed at 6, 9, and 12 weeks by clinical photography and patient satisfaction scores. Results, The majority of subjects displayed "moderate" (50%) or "slight" (25%) response to treatment at investigator assessment. Treatment of the periorbital region was reported more effective than the nasolabial region. At 12-week follow-up, 91% of subjects reported improved skin tone, and 82% reported enhanced smoothness of skin in the treatment area. Conclusion, Good response to LED therapy has been shown in this modest sample. Larger trials are needed to assess optimum frequency of light treatments and overall treatment time. [source] Imaging brain activity during natural vision using CASL perfusion fMRIHUMAN BRAIN MAPPING, Issue 7 2007Hengyi Rao Abstract Functional MRI (fMRI) has begun to be used to explore human brain activity during ecological and natural conditions. Arterial spin labeling (ASL) perfusion fMRI provides an appealing approach for imaging sustained brain activity during natural conditions because of its long-term temporal stability and ability to noninvasively quantify absolute cerebral blood flow (CBF). The present study used ASL perfusion fMRI to measure brain activation patterns associated with natural vision by concurrently recording CBF and blood oxygen level-dependent (BOLD) contrasts while subjects were freely viewing a cartoon movie. Reliable quantitative whole-brain CBF values (,60 mL/100g/min) as well as regional CBF values (45,80 mL/100g/min) were measured during movie viewing and resting states. The perfusion contrast revealed CBF increases in multiple visual pathway areas and frontal areas, and CBF decreases in ventromedial frontal cortex and superior temporal cortex during movie viewing compared to resting states. Concurrent BOLD contrast revealed similar but weaker activation and deactivation patterns. Regression analyses of both CBF data and BOLD data showed significant associations between activation in the middle temporal (MT) region and subjects' perception of motion. Region of interest analysis based on a priori literature-defined MT demonstrated significant monotonic stepwise associations between the intensity of motion perception and the CBF and BOLD signal changes. These results demonstrate the feasibility of using ASL perfusion fMRI for imaging both sustained and dynamic effects in neural activation during natural and ecologically valid situations, and support the notion of maintained functional segregation and specialization during natural vision. Hum Brain Mapp, 2006. © 2006 Wiley-Liss, Inc. [source] A comparison between human magnetostimulation thresholds in whole-body and head/neck gradient coilsMAGNETIC RESONANCE IN MEDICINE, Issue 2 2001Blaine A. Chronik Gradient coil magnetostimulation thresholds were measured in a group of 20 volunteers in both a whole-body gradient coil and a head/neck gradient coil. Both coils were operated using both x and y axes simultaneously (xy oblique mode). The waveform applied was a 64-lobe trapezoidal train with 1-ms flat-tops and varying rise times. Thresholds were based on the subjects' perception of stimulation, and painful sensations were not elicited. Thresholds were expressed in terms of the total gradient excursion required to cause stimulation as a function of the duration of the excursion. Thresholds for each subject were fit to a linear model, and values for the threshold curve slope (SRmin) and vertical axis intercept (,Gmin) were extracted. For the body coil, the mean values were: SRmin = 62.2 mT/m/ms, ,Gmin = 44.4 mT/m. For the head/neck coil, the mean values were: SRmin = 87.3 mT/m/ms, ,Gmin = 78.9 mT/m. These curve parameters were combined with calculated values for the induced electric field as a function of position within the coil to yield the tissue specific parameters Er (electric field rheobase) and ,c (chronaxie). For tissue stimulated within the body coil, the mean values were: Er = 1.8 V/m, ,c = 770 ,s. For tissue stimulated within the head/neck coil, the mean values were: Er = 1.3 V/m, ,c = 1100 ,s. Scalar potential contributions were not included in the calculation of induced electric fields. The mean threshold curves were combined with the gradient system performance curves to produce operational limit curves. The operational limit curves for the head/neck coil system were verified to be higher than those of the whole-body coil; however, the head/neck system was also found to be physiologically limited over a greater range of its operation than was the body coil. Subject thresholds between the two coils were not well correlated. Magn Reson Med 46:386-394, 2001. © 2001 Wiley-Liss, Inc. [source] How much of a priority is treating erectile dysfunction?DIABETIC MEDICINE, Issue 3 2003A study of patients' perceptions Abstract Background Erectile dysfunction (ED) is one complication of diabetes for which the treatment is rationed. Despite considerable public debate there has been no formal assessment of the views of patients and sufferers of the priority of treating ED. Aims To determine the perceptions of diabetic patients of the relative priority of treating ED in comparison with treatments for other diabetic complications and common medical conditions. Methods Psychological measures were used to assess subjects' perceptions of the relative importance of ED in comparison with eight other common problems (blindness, foot ulcers, high blood pressure, impotence, kidney disease, high cholesterol, migraine, mild indigestion and sleeping difficulties). The concept of willingness to pay was used to assess the amount per month participants would be prepared to pay for treatment for ED and other conditions. Four groups (controls, healthy diabetic men, impotent diabetic men and impotent diabetic men not in a sexual relationship) were studied. Results Significant differences were found between the four groups with regard to the ranking of the importance of ED compared with other health problems. Impotent diabetic male patients were prepared to pay more for treatment for their condition than all other conditions except blindness and renal failure. Conclusions Men with diabetes, in particular ED sufferers, believe ED has a major impact on quality of life and is as important to treat as many other conditions associated with diabetes. Diabet. Med. 20, 205,209 (2003) [source] Assessing the responsiveness of measures of oral health-related quality of lifeCOMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY, Issue 1 2004David Locker Abstract ,,, Objectives: This paper illustrates ways of assessing the responsiveness of measures of oral health-related quality of life (OHRQoL) by examining the sensitivity of the oral health impact profile (OHIP)-14 to change when used to evaluate a dental care program for the elderly. Methods: One hundred and sixteen elderly patients attending four municipally funded dental clinics completed a copy of the OHIP-14 prior to treatment and 1 month after the completion of treatment. The post-treatment questionnaire also included a global transition judgement that assessed subjects' perceptions of change in their oral health following treatment at the clinics. Change scores were calculated by subtracting post-treatment OHIP-14 scores from pre-treatment scores. The longitudinal construct validity of these change scores were assessed by means of their association with the global transition judgements. Measures of responsiveness included effect sizes for the change scores, the minimal important difference, and Guyatt's responsiveness index. An receiver operating characteristic (ROC) curve was constructed to determine the accuracy of the change scores in predicting whether patients had improved or not as a result of the treatment. Results: Based on the global transition judgements, 60.2% of subjects reported improved oral health, 33.6% reported no change, and only 6.2% reported that it was a little worse. These changes are reflected in mean pre- and post-treatment OHIP-14 scores that declined from 15.8 to 11.5 (P < 0.001). Mean change scores showed a consistent gradient in the expected direction across categories of the global transition judgement, but differences between the groups were not significant. However, paired t -tests showed no significant differences in the pre- and post-treatment scores of stable subjects, but showed significant declines for subjects who reported improvement. Analysis of data from stable subjects indicated that OHIP-14 had excellent test,retest reliability with an intraclass correlation coefficient (ICC) of 0.84. Effect size based on change scores for all subjects and subgroups of subjects were small to moderate. The ROC analysis indicated that OHIP-14 change scores were not good ,diagnostic tests' of improvement. The minimal important difference for the OHIP-14 was of 5-scale points, but detecting this difference would require relatively large sample sizes. Conclusions: OHIP-14 appeared to be responsive to change. However, the magnitude of change that it detected in the context described here was modest, probably because it was designed primarily as a discriminative measure. The psychometric properties of the global transition judgements that often provide the ,gold standard' for responsiveness studies need to be established. [source] | ||||||||||