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Stronger Decrease (stronger + decrease)
Selected AbstractsTributyltin uptake and depuration in Hyalella azteca: Implications for experimental designENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 2 2004Adrienne J. Bartlett Abstract The purpose of this study was to address four aspects of the kinetics of tributyltin (TBT) in the freshwater amphipod Hyalella azteca: time to steady state, route of uptake, depuration rates, and effect of gut clearance. The amphipods accumulated TBT rapidly, reaching steady state within 14 d. Body concentrations were similar between caged and sediment-exposed animals, indicating that the primary route of uptake is via dissolved TBT. However, the rate of uptake was significantly higher in sediment-exposed amphipods. During depuration, body concentrations of TBT exhibited a biphasic decline, with a stronger decrease over the first 24 h that is attributed primarily to gut clearance, followed by a more gradual decrease most likely due to excretion from the body. Gut contents contributed significantly to body concentrations of TBT, accounting for 30% of the initial total body burden in sediment-exposed amphipods. Half-lives of TBT in gut-cleared H. azteca were 8 d and 14 d for amphipods exposed to spiked water and spiked sediment, respectively. The results of this study have significant implications in the experimental design and interpretation of studies involving the effects of TBT in H. azteca. [source] Facial nerve injury-induced disinhibition in the primary motor cortices of both hemispheresEUROPEAN JOURNAL OF NEUROSCIENCE, Issue 6 2000Tamás Farkas Abstract Unilateral facial nerve transection induces plastic reorganization of the somatotopic order in the primary motor cortex area (MI). This process is biphasic and starts with a transient disinhibition of connections between cortical areas in both hemispheres. Little is known about the underlying mechanisms. Here, cortical excitability has been studied by paired pulse electrical stimulation, applied either within the MI or peripherally to the trigeminal nerve, while the responses were recorded bilaterally in the MI. The ratios between the amplitudes of the second and first evoked potentials (EPs or fEPSPs) were taken as measures of the inhibitory capacity in the MI ipsilateral or contralateral to the nerve injury. A skin wound or unilateral facial nerve exposure immediately caused a transient facilitation, which was followed by a reset to some level of inhibition in the MI on both sides. After facial nerve transection, the first relatively mild reduction of inhibition started shortly (within 10 min) after denervation. This was followed by a second step, involving a stronger decrease in inhibition, 40,45 min later. Previous publications have proved that sensory nerve injury (deafferentation) induces disinhibition in corresponding areas of the sensory cortex. It is now demonstrated that sham operation and, to an even greater extent, unilateral transection of the purely motoric facial nerve (deefferentation), each induce extended disinhibition in the MIs on both sides. [source] Trends in the southern oscillation phenomenon and Australian rainfall and changes in their relationshipINTERNATIONAL JOURNAL OF CLIMATOLOGY, Issue 3 2004Ramasamy Suppiah Abstract An attempt has been made to investigate decadal-scale trends in Australian rainfall and in the southern oscillation index (SOI) and their influence on the relationship between them. Monthly rainfall data from high-quality stations in Australia (from 1900 to 1995), India, Sri Lanka and Tahiti are used. The relationship between the SOI and Australian rainfall is positive, but shows decadal-scale variations during the past century. Although there were extended and severe El Niño events in the early 1990s and in 1997, Australia did not experience the expected severe rainfall deficiencies characteristic of previous events. However, severe drought conditions over eastern Australia were associated with a moderate El Niño event during 2002,03. Long-term fluctuations of March,May (MAM) rainfall show high-frequency variations, but trends during June,August (JJA), September,November (SON) and December,February (DJF) show low-frequency or decadal-scale variations. Trends and multi-decadal fluctuations in all-Australian spring (SON) and summer (DJF) rainfall are strongly dominated by rainfall trend fluctuations in northern and eastern Australia. Austral summer rainfall shows an increasing trend during the 1980s and 1990s, particularly in Queensland and New South Wales, despite the occurrence of extended and severe El Niños. However, some parts of New South Wales and Queensland experienced severe rainfall deficiencies during 2002,03 in conjunction with an El Niño event. The relationship between the SOI and rainfall on the interannual time scale is strong when the SOI and rainfall follow the same direction, but it is weak when they follow opposite directions on a decadal-time scale. The poor correlation during the 1920s and 1930s was due to a slightly increasing trend in the SOI and a stronger decreasing trend in rainfall. A weakening in the relationship between the SOI and rainfall in recent years, after the mid-1970s, is due to a small increase in rainfall in the 1980s and 1990s and a strong decrease in the SOI. Rainfall trends were enhanced (stronger decreases or increases) when the influence of the SOI (or El Niño-southern oscillation (ENSO)) was removed. Enhanced increases and decreases are particularly strong during SON and DJF, when the ENSO phenomenon is at the mature stage and also the influence on Australian rainfall is strong. The increasing trend in rainfall during the 1980s and 1990s in some parts of eastern Australia and the decreasing trend in the SOI result in more rainfall for a given SOI compared with the same SOI during the previous period, i.e. before the mid-1970s. A similar analysis was carried out for two periods, before and after 1972, for Tahiti, India and Sri Lanka. The upward or downward shift in regression lines is very clear during the season, that shows a strong relationship between rainfall and the SOI. Moreover, strengthening or weakening of the relationship between rainfall and the SOI is largely dependent on their multi-decadal variations and trends during the past century. Increases in rainfall during the 1980s and the 1990s and decreases in the SOI have weakened their relationship, both in Australia and India. Such a relationship gives more rainfall for a given SOI after 1973. The pattern was reversed for Sri Lanka, where rainfall during the second intermonsoon season has decreased. Analyses of trends in temperature at Darwin and Tahiti and of rainfall over Australia, India, Tahiti and Sri Lanka suggest a regional-scale change in climate, whereas the SOI reflects a change in the large-scale circulation pattern over the Indo-Pacific region after the mid-1970s. Copyright © 2004 Royal Meteorological Society [source] Cortical processing of near-threshold tactile stimuli: An MEG studyPSYCHOPHYSIOLOGY, Issue 3 2010Anja Wühle Abstract In the present study we tested the applicability of a paired-stimulus paradigm for the investigation of near-threshold (NT) stimulus processing in the somatosensory system using magnetoencephalography. Cortical processing of the NT stimuli was studied indirectly by investigating the impact of NT stimuli on the source activity of succeeding suprathreshold test stimuli. We hypothesized that cortical responses evoked by test stimuli are reduced due to the preactivation of the same finger representation by the preceding NT stimulus. We observed attenuation of the magnetic responses in the secondary somatosensory (SII) cortex, with stronger decreases for perceived than for missed NT stimuli. Our data suggest that processing in the primary somatosensory cortex including recovery lasts for <200 ms. Conversely, the occupancy of SII lasts ,500 ms, which points to its role in temporal integration and conscious perception of sensory input. [source] | ||||||||||