Special Demands (special + demand)

Distribution by Scientific Domains


Selected Abstracts


Treatment principles of atopic dermatitis

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY & VENEREOLOGY, Issue 1 2002
K. Thestrup-Pedersen
Abstract Atopic dermatitis (AD) is today the most common, chronic inflammatory skin disease among children in developed countries. Its cumulative prevalence varies from 20% in northern Europe and the USA to approximately 5% in Mediterranean countries. As a chronic disease it puts a special demand on treatment. There is no curative therapy, but competent guidance on treatment principles can control the disease in most, if not all children. This article summarizes the evidence-based knowledge that relates to the treatment of atopic eczema. It also gives advice and opinions on prophylactic measures as these are the focus of interest from most parents. Learning objective This article should enable you to give advice and guidance to parents of children with AD, including what is necessary for diagnosis, what is of value and importance considering allergies and allergological investigations, allergen exposure, prophylactic measures, diets and indoor environment. Finally, you should be able to explain the diversity of treatment principles for parents. [source]


Performance of parallel preconditioners for adaptive hp FEM discretization of incompressible flows

INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, Issue 5 2002
Andrew C. Bauer
Abstract Adaptive hp finite element (FEM) approximations of incompressible flow make special demands on parallel solution algorithms. We report here on the performance of standard algebraic preconditioning techniques for the efficient solution of such problems. We employ a Schur complement scheme to eliminate the ,bubble' degrees of freedom associated with the velocity field, thus removing the zeros from the diagonals and enabling the use of standard algebraic techniques. Using new data management strategies and the PETSc library of iterative solvers for linear systems, numerical results for Jacobi, Block Jacobi and Additive Schwartz preconditioners are presented. Copyright © 2002 John Wiley & Sons, Ltd. [source]


The design of single particle laser mass spectrometers,

MASS SPECTROMETRY REVIEWS, Issue 2 2007
Daniel M. MurphyArticle first published online: 16 OCT 200
Abstract This review explores some of the design choices made with single particle mass spectrometers. Different instruments have used various configurations of inlets, particle sizing techniques, ionization lasers, mass spectrometers, and other components. Systematic bias against non-spherical particles probably exceeds a factor of 2 for all instruments. An ionization laser tradeoff is the relatively poor beam quality and reliability of an excimer laser versus the longer wavelengths and slower response time of an Nd-YAG laser. Single particle instruments can make special demands on the speed and dynamic range of the mass spectrometers. This review explains some of the choices made for instruments that were developed for different types of measurements in the atmosphere. Some practical design notes are also given from the author's experience with each section of the instrument. Published 2006 Wiley Periodicals, Inc., Mass Spec Rev 26:150,165, 2007 [source]


Purification, crystallization and preliminary X-ray diffraction studies of parakeet (Psittacula krameri) haemoglobin

ACTA CRYSTALLOGRAPHICA SECTION F (ELECTRONIC), Issue 10 2009
S. M. Jaimohan
Birds often show efficient oxygen management in order to meet the special demands of their metabolism. However, the structural studies of avian haemoglobins (Hbs) are inadequate for complete understanding of the mechanism involved. Towards this end, purification, crystallization and preliminary X-ray diffraction studies have been carried out for parakeet Hb. Parakeet Hb was crystallized as the met form in low-salt buffered conditions after extracting haemoglobin from crude blood by microcentrifugation and purifying the sample by column chromatography. Good-quality crystals were grown from 10% PEG 3350 and a crystal diffracted to about 2.8,Å resolution. Preliminary diffraction data showed that the Hb crystal belonged to the monoclinic system (space group C2), with unit-cell parameters a = 110.68, b = 64.27, c = 56.40,Å, , = 109.35°. Matthews volume analysis indicated that the crystals contained a half-tetramer in the asymmetric unit. [source]