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Slow

Distribution by Scientific Domains
Life Sciences26%
Medical Sciences26%
Chemistry13%
Earth and Environmental Science7%
Humanities and Social Sciences5%
Business, Economics, Finance and Accounting5%
Polymers and Materials Science4%
Engineering3%
Physics and Astronomy2%
4 Other Domains9%
Distribution within Life Sciences
Neuroscience15%
Anatomy & Physiology7%
36 Other Subdomains71%

Kinds of Slow

  • very slow
    		•

    Terms modified by Slow

  • slow activation
  • slow addition
  • slow change
  • slow component
  • slow conduction
  • slow conformational change
  • slow convergence
  • slow conversion
  • slow cooling
  • slow cooling rate
  • slow crack growth
  • slow decline
  • slow decrease
    		•
  • slow degradation
  • slow development
  • slow diffusion
  • slow evaporation
  • slow evolution
  • slow flow
  • slow freezing
  • slow growing
  • slow growth
  • slow growth rate
  • slow increase
  • slow isoform
  • slow kinetics
    		•
  • slow mixing
  • slow movement
  • slow muscle
  • slow onset
  • slow pathway
  • slow pathway ablation
  • slow pathway conduction
  • slow phase
  • slow process
  • slow progress
  • slow progression
  • slow rate
  • slow recovery
    		•
  • slow reduction
  • slow relaxation
  • slow release
  • slow response
  • slow speed
  • slow step
  • slow walking speed
  • slow wave
  • slow wave activity
  • slow wave sleep

    • Selected Abstracts

    WHY DID JAPAN'S TFP GROWTH SLOW DOWN IN THE LOST DECADE?

    THE JAPANESE ECONOMIC REVIEW, Issue 2 2006
    AN EMPIRICAL ANALYSIS BASED ON FIRM-LEVEL DATA OF MANUFACTURING FIRMS
    This study analyses the cause of the slowdown in Japan's TFP growth during the 1990s. Many preceding studies, examining the issue at the macro- or industry-level, have found that the slowdown was primarily due to the stagnation in TFP growth in the manufacturing sector. Using firm level panel data covering the entire sector, we investigate the causes of the TFP slowdown and find that the reallocation of resources from less efficient to more efficient firms was very slow and limited. This "low metabolism" seems to be an important cause for the slowdown in Japan's TFP growth. [source]

    High-frequency gamma oscillations coexist with low-frequency gamma oscillations in the rat visual cortex in vitro

    EUROPEAN JOURNAL OF NEUROSCIENCE, Issue 8 2010
    Olaleke O. Oke
    Abstract Synchronization of neuronal activity in the visual cortex at low (30,70 Hz) and high gamma band frequencies (> 70 Hz) has been associated with distinct visual processes, but mechanisms underlying high-frequency gamma oscillations remain unknown. In rat visual cortex slices, kainate and carbachol induce high-frequency gamma oscillations (fast-,; peak frequency , 80 Hz at 37°C) that can coexist with low-frequency gamma oscillations (slow-,; peak frequency , 50 Hz at 37°C) in the same column. Current-source density analysis showed that fast-, was associated with rhythmic current sink-source sequences in layer III and slow-, with rhythmic current sink-source sequences in layer V. Fast-, and slow-, were not phase-locked. Slow-, power fluctuations were unrelated to fast-, power fluctuations, but were modulated by the phase of theta (3,8 Hz) oscillations generated in the deep layers. Fast-, was spatially less coherent than slow-,. Fast-, and slow-, were dependent on ,-aminobutyric acid (GABA)A receptors, ,-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors and gap-junctions, their frequencies were reduced by thiopental and were weakly dependent on cycle amplitude. Fast-, and slow-, power were differentially modulated by thiopental and adenosine A1 receptor blockade, and their frequencies were differentially modulated by N -methyl- d -aspartate (NMDA) receptors, GluK1 subunit-containing receptors and persistent sodium currents. Our data indicate that fast-, and slow-, both depend on and are paced by recurrent inhibition, but have distinct pharmacological modulation profiles. The independent co-existence of fast-, and slow-, allows parallel processing of distinct aspects of vision and visual perception. The visual cortex slice provides a novel in vitro model to study cortical high-frequency gamma oscillations. [source]

    Amygdala amino acid and monoamine levels in genetically Fast and Slow kindling rat strains during massed amygdala kindling: a microdialysis study

    EUROPEAN JOURNAL OF NEUROSCIENCE, Issue 1 2004
    Rick S. Shin
    Abstract We investigated the neurochemistry of epileptic seizures in rats selectively bred to be seizure-prone (Fast) vs. seizure-resistant (Slow) to amygdala kindling. Microdialysis was used to measure levels of amino acids [glutamate, aspartate and gamma-aminobutyric acid (GABA)] and monoamines (noradrenaline, dopamine and serotonin) during ,massed' stimulation (MS) (every 6 min) of the ipsilateral amygdala for a total of 40 stimulation trials. Behavioral seizure profiles together with their afterdischarge thresholds (ADTs) and associated durations were assessed during the procedure, and subsequently were redetermined 1, 7 and 14 days later. Then normal ,daily' kindling commenced and continued until the animal reached the fully kindled state. During MS, several generalized seizures were triggered in Fast rats that were associated with long afterdischarge (AD) durations and intermittent periods of elevated thresholds, but in Slow rats, most stimulations were associated with stable ADTs and short ADs. Progressively increasing extracellular glutamate and decreasing GABA was observed in Fast rats during the MS, whereas Slow rats showed levels similar to baseline values. Levels of noradrenaline and dopamine, but not of serotonin, were also increased in both strains throughout the MS treatment. In Fast rats, a dramatic lengthening of AD durations occurred 7 and 14 days following MS, as well as subsequent strong positive transfer to daily kindling, all of which were not seen in Slow rats. Together, these results show that repeated, closely spaced stimulations of the amygdala can differentially alter excitatory and/or inhibitory transmitter levels in a seizure network, and that sensitivity to this manipulation is genetically determined. [source]

    EMG and Oxygen Uptake Responses During Slow and Fast Ramp Exercise in Humans

    EXPERIMENTAL PHYSIOLOGY, Issue 1 2002
    Barry W. Scheuermann
    This study examined the relationship between muscle recruitment patterns using surface electromyography (EMG) and the excess O2 uptake (ExV,O2) that accompanies slow (SR, 8 W min,1) but not fast (FR, 64 W min,1) ramp increases in work rate (WR) during exercise on a cycle ergometer. Nine subjects (2 females) participated in this study (25 ± 2 years, ± S.E.M.). EMG was obtained from the vastus lateralis and medialis and analysed in the time (root mean square, RMS) and frequency (median power frequency, MDPF) domain. Results for each muscle were averaged to provide an overall response and expressed relative to a maximal voluntary contraction (%MVC). ,V,O2/,WR was calculated for exercise below (S1) and above (S2) the lactate threshold (LT) using linear regression. The increase in RMS relative to the increase in WR for exercise below the LT (,RMS/,WR-S1) was determined using linear regression. Due to non-linearities in RMS above the LT, ,RMS/,WR-S2 is reported as the difference in RMS (,RMS) and the difference in WR (,WR) at end-exercise and the LT. SR was associated with a higher (P < 0.05) ,V,O2/,WR (S1, 9.3 ± 0.3 ml min,1 W,1; S2, 12.5 ± 0.6 ml min,1 W,1) than FR (S1, 8.5 ± 0.4 ml min,1 W,1; S2, 7.9 ± 0.4 ml min,1 W,1) but a similar ,RMS/,WR-S1 (SR, 0.11 ± 0.01% W,1; FR, 0.10 ± 0.01% W,1). ExV,O2 was greater (P < 0.05) in SR (3.6 ± 0.7 l) than FR (-0.7 ± 0.4 l) but was not associated with a difference in either ,RMS/,WR-S2 (SR, 0.14 ± 0.01% W,1; FR, 15 ± 0.02% W,1) or MDPF (SR, 2.6 ± 5.9%; FR, -15.4 ± 4.5%). The close matching between power output and RMS during SR and FR suggests that the ExV,O2 of heavy exercise is not associated with the recruitment of additional motor units since ExV,O2 was observed during SR only. Compared to the progressive decrease in MDPF observed during FR, the MDPF remained relatively constant during SR suggesting that either (i) there was no appreciable recruitment of the less efficient type II muscle fibres, at least in addition to those recruited initially at the onset of exercise, or (ii) the decrease in MDPF associated with fatigue was offset by the addition of a higher frequency of type II fibres recruited to replace the fatigued motor units. [source]

    Effects of temperature, ammonium and glucose concentrations on yeast growth in a model wine system

    INTERNATIONAL JOURNAL OF FOOD SCIENCE & TECHNOLOGY, Issue 10 2006
    Daniela D'Amato
    Summary In enology, alcoholic fermentation is a complex process involving several mechanisms. Slow and incomplete alcoholic fermentation is a chronic problem for the wine industry and factors leading to sluggish and stuck fermentations have been extensively studied and reviewed. The most studied cause of sluggish and stuck fermentation is the nitrogen content limitation. Nevertheless, other factors, such as temperature of fermentation and sugar concentration can affect the growth of yeasts. In this study we modelled the yeast growth-cycle in wine model system as a function of temperature, sugar and ammonium concentrations; the individual effects and the interaction of these factors were analysed by means of a quadratic response surface methodology. Cell concentrations and weight loss were monitored in the whole wine fermentation process. The results of central composite design show that lower is the availability of nitrogen, higher is the cell growth rate; moreover, initial nitrogen concentration also influences survival time of Saccharomyces cerevisiae. [source]

    Effect of Different Crop Densities of Winter Wheat on Recovery of Nitrogen in Crop and Soil within the Growth Period

    JOURNAL OF AGRONOMY AND CROP SCIENCE, Issue 3 2001
    K. Blankenau
    Previous experiments have shown that, at harvest of winter wheat, recovery of fertilizer N applied in early spring [tillering, Zadok's growth stage (GS) 25] is lower than that of N applied later in the growth period. This can be explained by losses and immobilization of N, which might be higher between GS 25 and stem elongation (GS 31). It was hypothesized that a higher crop density (i.e. more plants per unit area) results in an increased uptake of fertilizer N applied at GS 25, so that less fertilizer N is subject to losses and immobilization. Different crop densities of winter wheat at GS 25 were established by sowing densities of 100 seeds m,2 (Slow), 375 seeds m,2 (Scfp= common farming practice) and 650 seeds m,2 (Shigh) in autumn. The effect of sowing density on crop N uptake and apparent fertilizer N recovery (aFNrec = N in fertilized treatments , N in unfertilized treatments) in crops and soil mineral N (Nmin), as well as on lost and immobilized N (i.e. non-recovered N = N rate , aFNrec), was investigated for two periods after N application at GS 25 [i.e. from GS 25 to 15 days later (GS 25 + 15d), and from GS 25 + 15d to GS 31] and in a third period between GS 31 and harvest (i.e. after second and third N applications). Fertilizer N rates varied at GS 25 (0, 43 and 103 kg N ha,1), GS 31 (0 and 30 kg N ha,1) and ear emergence (0, 30 and 60 kg ha,1). At GS 25 + 15d, non-recovered N was highest (up to 33 kg N ha,1 and up to 74 kg N ha,1 at N rates of 43 and 103 kg N ha,1, respectively) due to low crop N uptake after the first N dressing. Non-recovered N was not affected by sowing density. Re-mineralization during later growth stages indicated that non-recovered N had been immobilized. N uptake rates from the second and third N applications were lowest for Slow, so non-recovered N at harvest was highest for Slow. Although non-recovered N was similar for Scfp and Shigh, the highest grain yields were found at Scfp and N dressings of 43 + 30 + 60 kg N ha,1. This combination of sowing density and N rates was the closest to common farming practice. Grain yields were lower for Shigh than for Scfp, presumably due to high competition between plants for nutrients and water. In conclusion, reducing or increasing sowing density compared to Scfp did not reduce immobilization (and losses) of fertilizer N and did not result in increased fertilizer N use efficiency or grain yields. Einfluß unterschiedlicher pflanzendichten von Winterweizen auf die Wiederfindung von Stickstoff in Pflanze und Boden während der Vegetationsperiode Aus Wintergetreideversuchen ist bekannt, daß zur Ernte die Wiederfindung von Düngerstickstoff aus der Andüngung (Bestockung, [GS-Skala nach Zadok] GS 25) im Aufwuchs und in mineralischer Form im Boden (Nmin) niedriger ist als die von Düngerstickstoff der Schosser-und Ährengaben. Dies kann auf höhere Verluste bzw. eine höhere Immobilisation von Düngerstickstoff zwischen GS 25 und Schoßbeginn zurückgeführt werden, da hier die N-Aufnahme der Pflanzen im Vergleich zu späteren Wachstumsstadien gering ist. Daraus wurde abgeleitet, daß eine Erhöhung der Pflanzendichte zu einer erhöhten Aufnahme von früh gedüngtem N führen könnte, so daß weniger Dünger-N für Verlust- und Immobilisationsprozesse im Boden verbleibt. Unterschiedliche Pflanzendichten wurden durch unterschiedliche Aussaatstärken im Herbst erreicht (Slow= 100 Körner m,2, Scfp [herkömmliche Praxis]= 375 Körner m,2, Shigh= 650 Körner m,2). In der folgenden Vegetationsperiode wurde der Einfluß der verschiedenen Aussaatstärken auf die N-Aufnahme, die apparente Wiederfindung von Dünger-N (aFNrec = N in gedüngten , N in ungedüngten Prüfgliedern) in Pflanzen und Nmin, sowie auf potentielle Verluste und Immobilisation von Dünger-N (N-Defizit = N-Düngung , aFNrec) für zwei Phasen im Zeitraum zwischen der ersten N-Gabe (GS 25) und der Schossergabe zu GS 31 (d. h. zwischen GS 25 und 15 Tagen später [GS 25 + 15d] und von GS 25 + 15d bis GS 31), sowie zwischen GS 31 und der Ernte (d. h. nach der zweiten und dritten N-Gabe) untersucht. Die N-Düngung variierte zu den Terminen GS 25 (0, 43, 103 kg N ha,1), GS 31 (0, 30 kg N ha,1) und zum Ährenschieben (0, 30, 60 kg N ha,1). Unabhängig von der Aussaatstärke war das N-Defizit zum Termin GS 25 + 15d am höchsten (bis zu 33 kg N ha,1 und 74 kg N ha,1 bei einer N-Düngung von 43 bzw. 103 kg N ha,1), da die N-Aufnahme durch die Pflanzen während der Bestockungsphase am geringsten war. Das N-Defizit zeigt vornehmlich immobilisierten N an, da zu späteren Terminen eine Re-Mobilisation von N auftrat. Zwischen GS 31 und der Ernte wurden für die Aussaatstärke Slow die geringsten Aufnahmeraten von Düngerstickstoff aus der Schosser- und Ährengabe errechnet, so daß für Slow die höchsten N-Defizitmengen ermittelt wurden. Obwohl die N-Defizitmengen für Scfp und Shigh annähernd gleich waren, wurden bei N-Düngung von 43 + 30 + 60 kg N ha,1 für Scfp die höchsten Kornerträge erzielt. Diese Kombination von Aussaatstärke und N-Düngung kann als praxisüblich bezeichnet werden. Für Shigh wurden vermutlich niedrigere Kornerträge erzielt, weil die Konkurrenz um Nährstoffe und Wasser zwischen den Pflanzen aufgrund der hohen Pflanzendichte am intensivsten war. Die Ergebnisse lassen den Schluß zu, daß eine Verringerung oder Erhöhung der Pflanzendichte über entsprechende Aussaatstärken nicht zu einer Reduktion der Dünger-N-Immobilisation (oder von N-Verlusten) führt und demnach auch nicht die Dünger-N-Ausnutzung durch die Bestände erhöht wird. [source]

    Accelerated Junctional Escape Rhythm with Retrograde P Waves Through Alternating Slow and Fast Pathways

    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Issue 7 2001
    ALAN ACKERMANN D.O.
    [source]

    Muscle fibre types and size distribution in sub-antarctic notothenioid fishes

    JOURNAL OF FISH BIOLOGY, Issue 6 2000
    D. A. Fernandez
    The presumptive tonic muscles fibres of Cottoperca gobio, Champsocephalus esox, Harpagifer bispinis, Eleginops maclovinus, Patagontothen tessellata, P. cornucola and Paranotothenia magellanica stained weakly or were unstained for glycogen, lipid, succinic dehydrogenase (SDHase) and myosin ATPase (mATPase) activity. Slow, intermediate and fast twitch muscle fibres, distinguished on the basis of the pH stability of their mATPases, showed intense, moderate and low staining activity for SDHase, respectively. Slow fibres were the major component of the pectoral fin adductor profundis muscle. The proportion of different muscle fibre types varied from the proximal to distal end of the muscle, but showed relatively little variation between species. The myotomes contained a lateral superficial strip of red muscle composed of presumptive tonic, slow twitch and intermediate fibres, thickening to a major wedge at the horizontal septum. All species also had characteristic secondary dorsal and ventral wedges of red muscle. The relative abundance and localization of muscle fibre types in the red muscle varied between species and with body size in the protandric hermaphrodite E. maclovinus. The frequency distribution of diameters for fast twitch muscle fibres, the major component of deep white muscle, was determined in fish of a range of body sizes. The absence of fibres <20 ,m diameter was used as a criterion for the cessation of muscle fibre recruitment. Fibre recruitment had stopped in P. tessellata of 13·8 cm LT and E. maclovinus of 32·8 cm LT, equivalent to 49 and 36·5% of their recorded maximum sizes respectively. As a result in 20-cm P. tessellata, the maximum fibre diameter was 300 ,m and 36% of fibres were in excess of 200 ,m. The unusually large maximum fibre diameter, the general arrangement of the red muscle layer and the extreme pH lability of the mATPase of fast twitch fibres are all common characters of the sub-Antarctic and Antarctic Notothenioids, including Cottoperca gobio, the suggested sister group to the Notothenidae. [source]

    Slow but steady progress in child health in Papua New Guinea

    JOURNAL OF PAEDIATRICS AND CHILD HEALTH, Issue 12 2004
    T Duke
    First page of article [source]

    Dissociated Activity and Pulmonary Vein Fibrillation Following Functional Disconnection:

    PACING AND CLINICAL ELECTROPHYSIOLOGY, Issue 6 2003
    Impact for the Arrhythmogenesis of Focal Atrial Fibrillation
    The present study sought to investigate the electrophysiological properties of isolated pulmonary veins following successful radiofrequency (RF) catheter ablation in patients with paroxysmal atrial fibrillation (PAF). Overall, 71 pulmonary veins in 37 consecutive patients (age:56 ± 9 years) with recurrent PAF were targeted for RF ablation at the ostial region in order to achieve a complete functional block. Following disconnection, the incidence of dissociated pulmonary vein (PV) activity and its response to orciprenalin were studied. RF ablation abolished conduction in 67 (94%) of 71 potentially arrhythmogenic PVs after a mean of10.7 ± 6.4 RFapplications for each PV. After ablation, spontaneous dissociated automatic activity (9 to 52 beats/min, median 27) was found in 6 out of 67 isolated PVs (left superior:n = 1, left inferior:n = 1, right superior:n = 2, common left PV:n = 2). Slight acceleration (13 to 68 beats/min, median 29) of dissociated PV activity was observed during infusion of orciprenalin. Following isolation, initiation of sustained or nonsustained local fibrillation was recorded in only two cases of the common left sided PV with preceding automatic activity. In one patient PV fibrillation occurred during orciprenalin infusion following a repetitive response to a dissociated automatic rhythm with increasing duration as well as destabilization. In the other patient, PV fibrillation occurred immediately after the occurrence of PV automaticity. Slow dissociated automatic rhythms are detectable within 9% of disconnected PVs. The unique anatomic substrate of common left PVs seem to favor the occurrence of local fibrillation following isolation. The initiation pattern of fibrillation within the isolated PV has pathophysiological implications and underlines the contribution of multiple factors to the onset and sustenance of PAF. (PACE 2003; 26:1363,1370) [source]

    Exploring cultural drivers for wildlife trade via an ethnoprimatological approach: a case study of slender and slow lorises (Loris and Nycticebus) in South and Southeast Asia

    AMERICAN JOURNAL OF PRIMATOLOGY, Issue 10 2010
    K.A.I. Nekaris
    Abstract Illegal and unsustainable trade in wildlife is a major conservation challenge. For Asian primates, economic and cultural traditions, and increased forest access mean that trade may have become detrimental for certain species. Slow and slender lorises (Nycticebus and Loris) are primates particularly prevalent in trade, determined until now by focused counts of lorises in regional markets. Here, we use international trade statistics and a participant,observer approach to assess culturally specific drivers for trade in lorises in South and Southeast Asia, to provide a broader context to help mitigate this practice. Analysis of international records for the last 30 years revealed that live animal trade was more prevalent than trade in body parts (slow lorises, 86.4%; slender lorises, 91.4%), with Laos, Cambodia, and Thailand the largest exporters. We then examine drivers of international and domestic trade based on long-term data from 1994,2009 in Sri Lanka, Cambodia, and Indonesia. We show that slender lorises are important in Sri Lankan folklore, but their use as pets and for traditional medicine is rare. Trade in Bengal slow and pygmy lorises in Cambodia for use in traditional medicines, a practice with deeply historical roots, is widespread. Despite its own set of myths about the magical and curative properties of lorises, trade in Javan, Bornean, and greater slow lorises in Indonesia is largely for pets. Conservation practices in Asia are often generalized and linked with the region's major religions and economies. We show here that, in the case of wildlife trade, culturally specific patterns are evident among different ethnic groups, even within a country. Revealing such patterns is the foundation for developing conservation management plans for each species. We suggest some participatory methods for each country that may aid in this process. Am. J. Primatol. 72:877,886, 2010. © 2010 Wiley-Liss, Inc. [source]

    Blepharokymographic Analysis of Eyelid Motion in Bell's Palsy

    THE LARYNGOSCOPE, Issue 2 2007
    Seung-Ho Choi MD
    Abstract Objective: To present characteristics of eyelid motion measured by blepharokymography in Bell's palsy patients and to discuss possible roles and limitations of blepharokymography. Study Design. Retrospective analysis. Methods: The study included 72 patients with Bell's palsy who presented to the Department of Otolaryngology at Asan Medical Center, Seoul, Korea, between April 2002 and March 2005, and who underwent both electroneuronography and blepharokymography. Parameters of eyelid motion were measured using revised blepharokymography. Correlations between blepharokymography and electroneuronography or House-Brackmann grade were examined by Spearman rank correlation and Kendall's ,-b correlation, respectively. Results: Compared with the normal side, all parameters of eyelid motion except opening time were decreased on the palsy side, with peak closing velocity showing the greatest difference (40.2%). On average, paralytic eyelids moved down 6.5 mm in 277 ms with a peak velocity of 55.4 mm/s, whereas normal eyelids moved down 9.7 mm in 214 ms, with a peak velocity of 142.6 mm/s. Subtle paralytic eyelid motion or "lid lag" could be objectively documented by blepharokymography to have longer and gentler downward slopes in displacement curves. Most blepharokymographic parameters correlated with ocular electroneuronography and House-Brackmann grade. Conclusions: Slow or incomplete closure of paralytic eyelids can be graphically and numerically analyzed by blepharokymography. Blepharokymography may be useful for evaluating status, predicting prognosis, and assessing effects of rehabilitative procedures, including gold weight implants in patients with facial palsy. [source]

    Slow Delayed Rectifier Potassium Current (IKs) and the Repolarization Reserve

    ANNALS OF NONINVASIVE ELECTROCARDIOLOGY, Issue 1 2007
    Norbert Jost Ph.D.
    The aim of this review is to present the properties of the slow component of the delayed rectifier potassium current (IKs) in the human ventricle. The review gives a detailed description of the physiology, molecular biology and pharmacology of the IKs current, including kinetic properties, genetic structures, agonists and antagonists. The authors also present the role of the IKs current in the human cardiac repolarization focusing on several pathophysiological situations, such as the LQT syndrome and the Torsade de Pointes arrhythmia. [source]

    Divergent selection and realized heritability for growth in the Japanese scallop, Patinopecten yessoensis Jay

    AQUACULTURE RESEARCH, Issue 9 2010
    Jun Liang
    Abstract In order to improve the production and accurately estimate response to selection, divergent selection for growth in shell height was conducted in a cultured population of the Japanese scallop Patinopecten yessoensis. Applying the same selection intensity ± 1.756 in upward and downward directions, three groups including two selected groups of Fast and Slow and one non-selected Control group were created, which were reared under the same environmental conditions at any stage. Differences always significantly existed among the three groups (P<0.05), except for larvae at day 1 and at day 5, and in the order of Fast>Control>Slow. The average standardized response to selection (SR), realized heritability (hR2) and genetic gain (GG) was 0.473%, 0.269% and 7.85% for the Fast group and 0.381%, 0.217% and 6.60% for the Slow group respectively. Moreover, significant differences (P<0.05) were detected between the fast and the slow lines in both SR and hR2, providing evidence for an asymmetric response in two directions. Performance in shell height is improved by 7.85% in the fast line after one generation selection, suggesting that mass selection for faster growth in a cultured population of the Japanese scallop is effective. [source]

    Slow versus rapid enteral feeding advancement in preterm newborn infants 1000,1499 g: a randomized controlled trial

    ACTA PAEDIATRICA, Issue 1 2010
    Sriram Krishnamurthy
    Abstract Aim:, To evaluate whether preterm neonates weighing 1000,1499 g at birth receiving rapid enteral feeding advancement at 30 mL/kg/day attain full feedings (180 mL/kg/day) earlier than those receiving slow enteral feeding advancement at 20 mL/kg/day without increase in the incidence of feeding intolerance or necrotizing enterocolitis. Methods:, A total of 100 stable intramural neonates weighing between 1000 and 1499 g and gestational age less than 34 weeks were randomly allocated to enteral feeding (expressed human milk or formula) advancement of 20 mL/kg/day (n = 50) or 30 mL/kg/day (n = 50). Results:, Neonates in the rapid feeding advancement group achieved full volume feedings before the slow advancement group (median 7 days vs. 9 days) (p < 0.001), had significantly fewer days of intravenous fluids (median 2 days vs. 3.4 days) (p < 0.001), shorter length of stay in hospital (median 9.5 days vs. 11 days) (p = 0.003) and regained birth weight earlier (median 16 days vs. 22 days) (p < 0.001). There were no statistical differences in the proportion of infants with apnea, feed interruption or feed intolerance. Conclusion:, Rapid enteral feeding advancements of 30 mL/kg/day are well tolerated by stable preterm neonates weighing 1000,1499 g. [source]

    A Dual Electrochrome of Poly-(3,4-Ethylenedioxythiophene) Doped by N,N,-Bis(3-sulfonatopropyl)-4-4,-bipyridinium,Redox Chemistry and Electrochromism in Flexible Devices

    CHEMSUSCHEM CHEMISTRY AND SUSTAINABILITY, ENERGY & MATERIALS, Issue 1 2010
    Shweta Bhandari
    Abstract An electrochromic zwitterionic viologen, N,N,-bis(3-sulfonatopropyl)-4-4,-bipyridinium, has been used for the first time for doping poly (3,4-ethylenedioxythiopene) (PEDOT) films during electropolymerization. Slow and fast diffusional rates for the monomer at deposition potentials of +1.2 and +1.8,V, respectively yielded the viologen-doped PEDOT films with granular morphology and with dendrite-like shapes. The dual electrochrome formed at +1.8,V, showed enhanced coloration efficiency, larger electrochemical charge storage capacity, and superior redox activity in comparison to its analogue grown at +1.2,V, thus demonstrating the role of dendritic shapes in amplifying electrochromism. Flexible electrochromic devices fabricated with the viologen-doped PEDOT film grown at +1.8,V and Prussian blue with an ionic liquid-based gel electrolyte film showed reversible coloration between pale and dark purple with maximum coloration efficiency of 187,cm2,C,1 at ,=693,nm. The diffusional impedance parameters and switching kinetics of the device showed the suitability of this dual electrochrome formed as a single layer for practical electrochromic cells. [source]

    Platelet function disorder in patients with coronary slow flow

    CLINICAL CARDIOLOGY, Issue 3 2005
    Dr. Mustafa Gökçe M.D.
    Abstract Background: Some patients evaluated for chest pain with angiographically normal coronary arteries show coronary slow flow phenomenon (CSFP) on angiography. Slow flow of dye in epicardial coronary arteries is also not an infrequent finding in patients during routine coronary angiography. The precise pathophysiology of CSFP is not known yet. Hypothesis: This study investigates the presence of platelet function disorders in patients with CSFP. Methods: The patient group included 24 patients with CSFP detected by coronary angiography via the TIMI "frame count" method, and a control group included 23 patients with normal coronary flow. Platelet aggregability induced by use of ristocetin, collagen, and adenosine diphosphate (ADP), was measured from all blood samples in both control and patient groups. Results: The ratio of platelet aggregability increased significantly in patients with CSFP compared with patients with normal coronary flow (ristocetin 57.6 ± 15 vs. 45.4 ± 17.1, collagen 62.9 ± 16.4 vs. 48.9 ± 25.3, ADP 59.4 ± 18 vs. 42.4 ± 15.2, p < 0.05). Conclusion: Platelet aggregability is increased in patients with CSFP. [source]

    East Africa: FDI Slows

    AFRICA RESEARCH BULLETIN: ECONOMIC, FINANCIAL AND TECHNICAL SERIES, Issue 9 2009
    Article first published online: 2 NOV 200
    No abstract is available for this article. [source]

    SOUTH AFRICA: Growth Slows

    AFRICA RESEARCH BULLETIN: ECONOMIC, FINANCIAL AND TECHNICAL SERIES, Issue 12 2009
    Article first published online: 6 FEB 200
    No abstract is available for this article. [source]

    Snap: A time critical decision-making framework for MOUT simulations

    COMPUTER ANIMATION AND VIRTUAL WORLDS (PREV: JNL OF VISUALISATION & COMPUTER ANIMATION), Issue 3-4 2008
    Shang-Ping Ting
    Abstract Deliberative reasoning based on the rational analysis of various alternatives often requires too much information and may be too slow in time critical situations. In these situations, humans rely mainly on their intuitions rather than some structured decision-making processes. An important and challenging problem in Military Operations on Urban Terrain (MOUT) simulations is how to generate realistic tactical behaviors for the non-player characters (also known as bots), as these bots often need to make quick decisions in time-critical and uncertain situations. In this paper, we describe our work on Snap, a time critical decision-making framework for the bots in MOUT simulations. The novel features of Snap include case-based reasoning (CBR) and thin slicing. CBR is used to make quick decisions by comparing the current situation with past experience cases. Thin slicing is used to model human's ability to quickly form up situation awareness under uncertain and complex situations using key cues from partial information. To assess the effectiveness of Snap, we have integrated it into Twilight City, a virtual environment for MOUT simulations. Experimental results show that Snap is very effective in generating quick decisions during time critical situations for MOUT simulations. Copyright © 2008 John Wiley & Sons, Ltd. [source]

    Fast, Exact, Linear Booleans

    COMPUTER GRAPHICS FORUM, Issue 5 2009
    Gilbert Bernstein
    Abstract We present a new system for robustly performing Boolean operations on linear, 3D polyhedra. Our system is exact, meaning that all internal numeric predicates are exactly decided in the sense of exact geometric computation. Our BSP-tree based system is 16-28× faster at performing iterative computations than CGAL's Nef Polyhedra based system, the current best practice in robust Boolean operations, while being only twice as slow as the non-robust modeler Maya. Meanwhile, we achieve a much smaller substrate of geometric subroutines than previous work, comprised of only 4 predicates, a convex polygon constructor, and a convex polygon splitting routine. The use of a BSP-tree based Boolean algorithm atop this substrate allows us to explicitly handle all geometric degeneracies without treating a large number of cases. [source]

    Skeletal muscle fibre diversity and the underlying mechanisms

    ACTA PHYSIOLOGICA, Issue 4 2010
    M. Canepari
    Abstract The review first briefly summarizes how myosin isoforms have been identified as the major determinant of the functional variability among skeletal muscle fibres. The latter feature is a major characteristic of muscle fibres and a major basis of skeletal muscle heterogeneity and plasticity in vivo. Then, evidence is reported, which indicates that the properties of muscle fibres can vary with no change in the myosin isoform they express. Moreover, the physiological and pathological conditions (ageing, disuse, exercise training, muscular dystrophy) in which such myosin isoform independent change in functional properties occurs and the possible underlying mechanisms are considered. Finally, the known molecular bases of the functional differences among slow and fast isoforms are briefly dealt with. [source]

    Wildfire Policy and Public Lands: Integrating Scientific Understanding with Social Concerns across Landscapes

    CONSERVATION BIOLOGY, Issue 4 2004
    MICHAEL P. DOMBECK
    administración de bosques; fuego no controlado; política; Servicio Forestal Estados Unidos; tierras públicas Abstract:,Efforts to suppress wildfires have become increasingly problematic in recent years as costs have risen, threats to firefighter safety have escalated, and detrimental impacts to ecosystems have multiplied. Wildfires that escape initial suppression often expand into large, high-intensity summer blazes. Lost is the legacy of smaller fires that likely burned outside extreme weather and fuel conditions and resulted in less severe impacts. Despite the recognized need for modifications to existing policies and practices, resource agencies have been slow to respond. The spread of exotic species, climate change, and increasing human development in wildlands further complicates the issue. New policies are needed that integrate social and ecological needs across administrative boundaries and broad landscapes. These policies should promote a continuum of treatments with active management and reduction of fuel hazard in wildland-urban interface zones and reintroduction of fire in wildlands. Management goals should focus on restoration of the long-term ecological health of the land. Projects that reduce fuel loads but compromise the integrity of soil, water supplies, or watersheds will do more harm than good in the long run. Despite significant ecological concerns, learning to live with fire remains primarily a social issue that will require greater political leadership, agency innovation, public involvement, and community responsibility. Resumen:,En años recientes, los esfuerzos para suprimir los fuegos no controlados se han vuelto cada vez más problemáticos por el incremento de costos, el aumento de las amenazas a la seguridad de bomberos y se la multiplicio, de los impactos perjudiciales a los ecosistemas. Los incendios que escapan la supresión inicial a menudo se expanden a grandes conflagraciones estivales de alta intensidad. Se ha perdido el legado de fuegos menores que probablemente se llevaban a cabo en condiciones climáticas y de combustible extremas que tenían impactos menos severos. A pesar del reconocimiento de la necesidad de modificaciones a las políticas y prácticas actuales, las agencias han respondido lentamente. La expansión de especies exóticas, el cambio climático y el incremento del desarrollo humano en áreas silvestres complican el problema aún más. Se requieren políticas nuevas que integren necesidades sociales y ecológicas más allá de límites administrativos y en paisajes amplios. Estas políticas deben promover un continuo de tratamientos con gestión activa y reducción de riesgo de combustión en la interfase área silvestre-urbana y la reintroducción de fuego en áreas silvestres. Las metas de la gestión deben enfocar en la restauración de la salud ecológica a largo plazo. Los proyectos que reducen la carga de combustible pero que comprometen la integridad del suelo, las reservas de agua o cuencas hidrológicas no serán de mucha utilidad en el largo plazo. A pesar de preocupaciones ecológicas significativas, aprender a vivir con fuego seguirá siendo un aspecto social que requerirá de mayor liderazgo político, innovación de agencias, participación del público y responsabilidad comunitaria. [source]

    Incorporating Uncertainty into Demographic Modeling: Application to Shark Populations and Their Conservation

    CONSERVATION BIOLOGY, Issue 4 2002
    Enric Cortés
    I used age-structured life tables and Leslie matrices based on a prebreeding survey and a yearly time step applied only to females to model the demography of 41 populations from 38 species of sharks representing four orders and nine families. I used Monte Carlo simulation to reflect uncertainty in the estimates of demographic traits and to calculate population statistics and elasticities for these populations; I used correlation analysis to identify the demographic traits that explained most of the variation in population growth rates ( , ). The populations I examined fell along a continuum of life-history characteristics that can be linked to elasticity patterns. Sharks characterized by early age at maturity, short lifespan, and large litter size had high , values and short generation times, whereas sharks that mature late and have long lifespans and small litters have low , values and long generation times. Sharks at the "fast" end of the spectrum tended to have comparable adult and juvenile survival elasticities, whereas sharks at the "slow" end of the continuum had high juvenile survival elasticity and low age,zero survival ( or fertility ) elasticity. Ratios of adult survival to fertility elasticities and juvenile survival to fertility elasticities suggest that many of the populations studied do not possess the biological attributes necessary to restore , to its original level after moderate levels of exploitation. Elasticity analysis suggests that changes in juvenile survival would have the greatest effect on ,, and correlation analysis indicates that variation in juvenile survival, age at maturity, and reproduction account for most of the variation in ,. In general, combined results from elasticity and correlation analyses suggest that research, conservation, and management efforts should focus on these demographic traits. Resumen: Exploré los efectos de la incertidumbre en los caracteres demográficos en análisis demográficos de tiburones, un método no empleado con anterioridad para este taxón. Utilicé tablas de vida estructuradas por edades y matrices de Leslie basadas en evaluaciones pre-gestación y pasos de tiempo de un año aplicados solo a las hembras para modelar la demografía de 41 poblaciones de 38 especies de tiburones que representan cuatro órdenes y nueve familias. Utilicé la simulación de Monte Carlo para reflejar la incertidumbre en las estimaciones de caracteres demográficos y calcular las estadísticas y elasticidades poblacionales para estas poblaciones y el análisis de correlación para identificar los caracteres demográficos que explican la mayoría de la variación en las tasas de crecimiento poblacional ( , ). Las poblaciones examinadas caen dentro de un continuo de características de historias de vida que pueden estar vinculadas con los patrones de elasticidad. Los tiburones que maduran a temprana edad y tienen corta duración de vida y grupos grandes de crías tuvieron valores altos de , y tiempos generacionales cortos, mientras que los tiburones que maduran tarde y tienen una duración de vida larga y grupos pequeños de crías tienen valores bajos de , y tiempos generacionales largos. Los tiburones que se encuentran en el punto final "rápido" del espectro tendieron a tener elasticidades de supervivencia de adultos y juveniles comparables, mientras que los tiburones en el punto final "lento" del continuo tuvieron una alta elasticidad de supervivencia de juveniles y una baja elasticidad en supervivencia a la edad cero (o fertilidad ). Las proporciones de elasticidades de supervivencia de adultos y fertilidad y de elasticidades de supervivencia de juveniles y fertilidad sugieren que muchas de las poblaciones estudiadas no poseen los atributos biológicos necesarios para restaurar , a su nivel original después de niveles moderados de explotación. El análisis de elasticidad sugiere que en la supervivencia de juveniles se podría tener el efecto mayor de , y el análisis de correlación indica que la variación en la supervivencia de juveniles, la edad de maduración y reproducción explican la mayor parte de la variación en ,. En general, los resultados combinados de los análisis de elasticidad y correlación sugieren que los esfuerzos de investigación, conservación y manejo deberían enfocarse a estas características demográficas. [source]

    Protective effects of exercise preconditioning on hindlimb unloading-induced atrophy of rat soleus muscle

    ACTA PHYSIOLOGICA, Issue 1 2009
    H. Fujino
    Abstract Aim:, A chronic decrease in the activation and loading levels of skeletal muscles as occurs with hindlimb unloading (HU) results in a number of detrimental changes. Several proteolytic pathways are involved with an increase in myofibrillar protein degradation associated with HU. Exercise can be used to counter this increase in proteolytic activity and, thus, may be able to protect against some of the detrimental changes associated with chronic decreased use. The purpose of the present study was to determine the potential of a single bout of preconditioning endurance exercise in attenuating the effects of 2 weeks of HU on the mass, phenotype and force-related properties of the soleus muscle in adult rats. Methods:, Male Wistar rats were subjected to HU for 2 weeks. One half of the rats performed a single bout of treadmill exercise for 25 min immediately prior to the 2 weeks of HU. Results:, Soleus mass, maximum tetanic tension, myofibrillar protein content, fatigue resistance and percentage of type I (slow) myosin heavy chain were decreased in HU rats. In addition, markers for the cathepsin, calpain, caspase and ATP-ubiquitin-proteasome proteolytic pathways were increased. The preconditioning endurance exercise bout attenuated all of the detrimental changes associated with HU, and increased HSP72 mRNA expression and protein levels. Conclusion:, These findings indicate that exercise preconditioning may be an effective countermeasure to the detrimental effects of chronic decreases in activation and loading levels on skeletal muscles and that an elevation in HSP72 may be one of the mechanisms associated with these responses. [source]

    Towards Fast Measurement of the Electron Temperature in the SOL of ASDEX Upgrade Using Swept Langmuir Probes

    CONTRIBUTIONS TO PLASMA PHYSICS, Issue 9 2010
    H.W. Müller
    Abstract On ASDEX Upgrade first experiments were made using single probes with a voltage sweep frequency up to 100kHz. Possibilities and limitations using fast swept probes with a standard diagnostic and analysis tools are discussed. A good agreement between the data derived from fast swept single probe characteristics and floating as well as saturation current measurements was found. In a stationary (non ELMing) plasma the data of the fast swept probe are compared to standard slow swept probes (kHz range) showing an improvement of the measurement by faster sweeping. While ELM filaments already could be resolved the access of electron temperature fluctuations in small scale turbulence still has to be improved. Further comparisons are done in ELMy H-mode with combined ball-pen probe/floating potential measurements which can deliver electron temperatures with 25 , s time resolution at reduced spatial resolution compared to pin probes. During ELMs the electron temperatures derived from the ball-pen probe and fast swept single probes agreed (© 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source]

    Changes in the contractile properties of motor units in the rat medial gastrocnemius muscle after one month of treadmill training

    ACTA PHYSIOLOGICA, Issue 4 2008
    M. Pogrzebna
    Abstract Aim:, The influence of 4 weeks treadmill training on the contractile properties of motor units (MUs) in the rat medial gastrocnemius muscle was investigated. Methods:, A population of 18 Wistar rats was divided into two groups: trained on a treadmill (n = 7, locomotion speed 27 cm s,1, 1 km daily, 5 days a week, for 4 weeks) and control (n = 11). The contractile properties of isolated MUs were studied. Functional isolation of units was achieved by electrical stimulation of filaments of the ventral roots. A total of 299 MUs were investigated (142 in the control group and 157 in the trained group). They were divided into fast fatigable (FF), fast resistant to fatigue (FR) and slow (S). Their proportions and parameters of contractions were analysed. Results:, Following training, the number of FF units decreased and the number of FR units increased. The distribution of the fatigue index changed within these two types of fast units. The twitch and tetanus forces increased considerably in fast MUs, mainly in those of the FF type. The contraction and relaxation times shortened in the FR and S MUs. The steep part of the force,frequency curves shifted towards higher stimulation frequencies in FR and S units, while in FF units the shift was in the opposite direction. Conclusion:, The significant change in the proportions of fast MUs following training indicates FF to FR transformation. The various effects of training seen in the different MU types help explain the rationale behind mixed training. [source]

    Dielectric relaxation in ferroelectric TlInS2 layered crystals within metastable chaotic state

    CRYSTAL RESEARCH AND TECHNOLOGY, Issue 6 2007
    entürk
    Abstract The results of investigations low frequency dielectric relaxation in layered ferroelectric TlInS2 crystals are presented. The measurements were performed in the temperature range of 180-230 K and in the frequency range of 5 kHz,1 MHz. Two different relaxation processes were observed in mentioned temperature interval. The crystal has "slow" and "fast" relaxation mechanisms in low and high frequency region, respectively. The presence of two different relaxation mechanisms in TlInS2 is discussed. (© 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source]

    Respiratory muscle performance with stretch-shortening cycle manoeuvres: maximal inspiratory pressure,flow curves

    ACTA PHYSIOLOGICA, Issue 3 2005
    G. E. Tzelepis
    Abstract Aim:, To test the hypothesis that the maximal inspiratory muscle (IM) performance, as assessed by the maximal IM pressure,flow relationship, is enhanced with the stretch-shortening cycle (SSC). Methods:, Maximal inspiratory flow,pressure curves were measured in 12 healthy volunteers (35 ± 6 years) during maximal single efforts through a range of graded resistors (4-, 6-, and 8-mm diameter orifices), against an occluded airway, and with a minimal load (wide-open resistor). Maximal inspiratory efforts were initiated at a volume near residual lung volume (RV). The subjects exhaled to RV using slow (S) or fast (F) manoeuvres. With the S manoeuvre, they exhaled slowly to RV and held the breath at RV for about 4 s prior to maximal inspiration. With the F manoeuvre, they exhaled rapidly to RV and immediately inhaled maximally without a post-expiratory hold; a strategy designed to enhance inspiratory pressure via the SSC. Results:, The maximal inspiratory pressure,flow relationship was linear with the S and F manoeuvres (r2 = 0.88 for S and r2 = 0.88 for F manoeuvre, P < 0.0005 in all subjects). With the F manoeuvre, the pressure,flow relationship shifted to the right in a parallel fashion and the calculated maximal power increased by approximately 10% (P < 0.05) over that calculated with the S manoeuvre. Conclusion:, The maximal inspiratory pressure,flow capacity can be enhanced with SSC manoeuvres in a manner analogous to increases in the force,velocity relationship with SSC reported for skeletal muscles. [source]

    Partial reversal of conduction slowing during repetitive stimulation of single sympathetic efferents in human skin

    ACTA PHYSIOLOGICA, Issue 3 2004
    M. Campero
    Abstract Aims:, To describe and identify the function of a class of human C fibre with an unusual response to repetitive electrical stimulation. Other C fibres slow progressively at 2 Hz (type 1), reach a latency plateau (type 2) or hardly slow at all (type 3). Methods:, C fibres innervating hairy skin were recorded by microneurography in the superficial peroneal nerves of 19 healthy volunteers. Baseline electrical stimulation of the skin was at 0.25 Hz, and activity-dependent slowing recorded during stimulation at 2 Hz for 3 min and after a 3-min pause in stimulation. Results:, In 41 units, there was a partial recovery of latency during repetitive stimulation. These were classified as ,type-4' units, and identified as sympathetic efferents, since they exhibited spontaneously activity, which was enhanced by manoeuvres that increase sympathetic outflow (15 of 16 cases) and/or suppressed by a proximal anaesthetic block (eight of eight cases). The peak slowing during 2 Hz trains averaged 6.47 ± 2.06% (mean ± SD, n = 41), but after 3 min the slowing had reduced to 4.90 ± 2.20%, which was less than in all type 1 (nociceptor) fibres but similar to that in type 2 (cold) fibres. Compared with cold fibres, type-4 sympathetic fibres slowed more after the first 10 impulses at 2 Hz (2.57 ± 0.45%) and also after a pause in stimulation (1.66 ± 0.51%). Conclusions:, The distinctive activity-dependent slowing profiles of these type-4 sympathetic C units may help identification in vitro, and suggest that hyperpolarization-activated channels have a particularly prominent role in the axonal membrane. [source]