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SimplePhos Ligands (SimplePho + ligand)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

ChemInform Abstract: Copper-Catalyzed Asymmetric Conjugate Addition with Grignard Reagents and SimplePhos Ligands.

CHEMINFORM, Issue 24 2010
Laetitia Palais
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Copper-Catalyzed Asymmetric Conjugate Addition with Chiral SimplePhos Ligands.

CHEMINFORM, Issue 8 2010
Laetitia Palais
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Copper-Catalyzed Asymmetric Conjugate Addition with Chiral SimplePhos Ligands,

CHEMISTRY - A EUROPEAN JOURNAL, Issue 40 2009
Laëtitia Palais
Abstract SimplePhos ligands represent a novel class of monodentate chiral ligands based on a chiral amine moiety and flexible diaryl groups on the phosphorous atom. They can be easily prepared by two different pathways and they can be highly functionalised. Herein we report the copper-catalysed asymmetric conjugate addition of diethyl zinc and trialkylaluminium reagents with SimplePhos ligands, which gives high enantioselectivity with cyclic enones, acyclic enones and nitro-olefins, with up to 98.6,%,ee. Of particular interest is the reaction of trialkylaluminium reagents with a wide range of 3-substituted enones, thus allowing the formation of stereogenic quaternary carbon centres. [source]