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Selected AbstractsHistometric and Histochemical Analysis of the Effect of Trichloroacetic Acid Concentration in the Chemical Reconstruction of Skin Scars MethodDERMATOLOGIC SURGERY, Issue 10 2006SUNG BIN CHO MD BACKGROUND Atrophic scars can be induced by various causes, including severely inflamed acne, chicken pox, and trauma. Many treatment modalities are used for reconstructing and improving the appearance of scars with various treatment results. OBJECTIVE A recent report shows the clinical efficacy of the chemical reconstruction of skin scars (CROSS) method, which consists of the focal application of trichloroacetic acid (TCA) in a higher concentration. Histometric analysis of the CROSS method, however, has not yet been established. METHODS In this study, five hairless mice were used to evaluate the effect of the CROSS method and to analyze the difference between the CROSS method and simple TCA application. RESULTS Similar histologic changes were observed in the two methods, including epidermal and dermal rejuvenation with new collagen deposition. These changes, however, were more prominent in the CROSS method,treated areas, particularly when 100% TCA was used. CONCLUSION The results of this study suggest that treatment of atrophic scars using the CROSS method is more effective than simple application of TCA in activating fibroblasts in the dermis and increasing the amount of collagen. [source] Necessary conditions for the N -representability of pair distribution functionsINTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY, Issue 7 2006Paul W. Ayers Abstract A necessary condition for the N -representability of the electron pair density proposed by one of the authors (E. R. D.) is generalized. This shows a link between this necessary condition and other, more widely known, N -representability conditions for the second-order density matrix. The extension to spin-resolved electron pair densities is considered, as is the extension to higher-order distribution functions. Although quantum mechanical systems are our primary focus, the results are also applicable to classical systems, where they reduce to an inequality originally derived by Garrod and Percus. As a simple application, bounds to the average angle between an electron pair are derived. It is shown that computational methods based on variational minimization of the energy with respect to the electron pair density can give extremely poor results unless robust N -representability constraints are considered. For reference, constraints for the N -representability of the pair density are summarized. © 2006 Wiley Periodicals, Inc. Int J Quantum Chem, 2006 [source] A Pricing Model for Quantity ContractsJOURNAL OF RISK AND INSURANCE, Issue 4 2004Knut K. Aase An economic model is proposed for a combined price futures and yield futures market. The innovation of the article is a technique of transforming from quantity and price to a model of two genuine pricing processes. This is required in order to apply modern financial theory. It is demonstrated that the resulting model can be estimated solely from data for a yield futures market and a price futures market. We develop a set of pricing formulas, some of which are partially tested, using price data for area yield options from the Chicago Board of Trade. Compared to a simple application of the standard Black and Scholes model, our approach seems promising. [source] A simple and practical method in treatment of ingrown nails: splinting by flexible tubeJOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY & VENEREOLOGY, Issue 10 2006S Nazari Abstract Background, The ingrown nail (or onychocryptosis) is a common problem that occurs mostly in the big toe and causes high amounts of morbidity in affected patients. Many therapeutic methods have been described, most of them leading to severe damage to the nail or to frequent relapses. The nail splinting technique is a successful, simple and non-invasive therapeutic method for treating ingrown nails. Objective, To determine efficacy of the plastic tube insertion technique in patients with ingrown toenail and its use as a standard treatment. Materials and Methods, We encountered 32 cases (age range 9,67 years) of ingrown toenails in this clinical trial. All of the patients were treated using the plastic nail tube insertion technique for 7 to 15 days. Patients were examined daily for the first 3 days of treatment and were evaluated 3 and 6 months after treatment. All patients were followed up by a single observer. Results, Recurrence was seen in only two patients after 6 months of treatment (6.25%). Conclusion, The low recurrence rate using the nail splinting technique in the treatment of ingrown toenail, as well as its simple application, shows that this treatment constitutes an effective, non-invasive method. It appears that this technique can substitute other more invasive surgical methods, particularly in the early stages of this disease. [source] A note on the estimation of mixture models under endogenous samplingTHE ECONOMETRICS JOURNAL, Issue 1 2003J. M. C. Santos Silva Summary. The main purpose of this paper is to highlight that, in the estimation of mixture models under endogenous sampling, the distribution of the unobservables can be specified either in the actual population or in the artificial population induced by the sampling method. Which of the two approaches is correct depends crucially on the population of interest. The importance of making the correct decision is illustrated with a simple application. [source] PCR as a specific, sensitive and simple method suitable for diagnosticsBIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION, Issue 4 2000M. Gonzalo Claros PCR technology is a widespread method that has not reached students laboratory in anything else than a typical amplification reaction. We describe a simple application of PCR in pathogen diagnostics that enables students to identify which ampicillin-resistant organism is present in a cell culture. This experiment has been performed for one year in two "Experimental Biochemistry and Molecular Biology" courses with Biological and Chemical undergraduates. Using specific primers from the Escherichia coli ,-lactamase gene, they have been able to selectively amplify a ,-lactamase DNA fragment in E. coli but not in Staphylococcus aureus and, using different annealing temperatures, test the reaction specificity. By solving the "Study Questions", students understood the specificity and sensitivity of the method, as well as the rationale that should be applied when a molecular weight pattern is used for calculating unknown DNA sizes. © 2000 IUBMB. Published by Elsevier Science Ltd. All rights reserved. [source] |