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Silicone Tube (silicone + tube)
Selected AbstractsA new endoscopic technique for suspension of esophageal prosthesis for refractory caustic esophageal stricturesDISEASES OF THE ESOPHAGUS, Issue 3 2008E. Ancona SUMMARY., There is no clear consensus concerning the best endoscopic treatment of benign refractory esophageal strictures due to caustic ingestion. Different procedures are currently used: frequent multiple dilations, retrievable self-expanding stent, nasogastric intubation and surgery. We describe a new technique to fix a suspended esophageal silicone prosthesis to the neck in benign esophageal strictures; this permits us to avoid the frequent risk of migration of the expandable metallic or plastic stents. Under general anesthesia a rigid esophagoscope was placed in the patient's hypopharynx. Using transillumination from the optical device, the patient's neck was pierced with a needle. A n.0 monofilament surgical wire was pushed into the needle, grasped by a standard foreign body forceps through the esophagoscope and pulled out of the mouth (as in percutaneous endoscopic gastrostomy procedure). After tying the proximal end of the silicone prosthesis with the wire, it was placed through the strictures under endoscopic view. This procedure was successfully utilized in four patients suffering from benign refractory esophageal strictures due to caustic ingestion. The prosthesis and its suspension from the neck were well-tolerated until removal (mean duration 4 months). A postoperative transitory myositis was diagnosed in only one patient. One of the most frequent complications of esophageal prostheses in refractory esophageal strictures due to caustic ingestion is distal migration. Different solutions were proposed. For example the suspension of a wire coming from the nose and then fixed behind the ear. This solution is not considered optimal because of patient complaints and moreover the aesthetic aspect is compromised. The procedure we utilized in four patients utilized the setting of a silicone tube hanging from the neck in a way similar to that of endoscopic pharyngostomy. This solution is a valid alternative both for quality of life and for functional results. [source] Enhanced rat sciatic nerve regeneration through silicon tubes filled with pyrroloquinoline quinoneMICROSURGERY, Issue 4 2005Shiqing Liu M.D. Pyrroloquinoline quinone (PQQ) is an antioxidant that also stimulates nerve growth factor (NGF) synthesis and secretion. In an earlier pilot study in our laboratory, Schwann cell growth was accelerated, and NGF mRNA expression and NGF secretion were promoted. The present study was designed to explore the possible nerve-inducing effect of PQQ on a nerve tube model over a 1-cm segmental deficit. An 8-mm sciatic nerve deficit was created in a rat model and bridged by a 1-cm silicone tube. Then,10 ,l of 0.03 mmol/l PQQ were perfused into the silicone chamber in the PQQ group. The same volume of normal saline was delivered in the control group. Each animal underwent functional observation (SFI) at 2-week intervals and electrophysiological studies at 4-week intervals for 12 weeks. Histological and morphometrical analyses were performed at the end of the experiment, 12 weeks after tube implantation. Using a digital image-analysis system, thickness of the myelin sheath was measured, and total numbers of regenerated axons were counted. There was a significant difference in SFI, electrophysiological index (motor-nerve conduct velocity and amplitude of activity potential), and morphometrical results (regenerated axon number and thickness of myelin sheath) in nerve regeneration between the PQQ group and controls (P < 0.05). More mature, high-density, newly regenerated nerve was observed in the PQQ group. We conclude that PQQ is a potent enhancer for the regeneration of peripheral nerves. © 2005 Wiley-Liss, Inc. Microsurgery 25:329,337, 2005. [source] Effectiveness of porto-intracaval shunt to reduce the negative effects of portal and caval clamping in the rabbitMICROSURGERY, Issue 4 2001Gaetano La Greca M.D., Ph.D. In performing experimental liver surgery, it is difficult to prolong anhepatic time because the animals do not tolerate prolonged portal and caval clamping. To counteract prolonged venous stasis, the authors previously developed a simple porto-intracaval shunt. The shunt consists of a self-constructed inverted Y silicone tube. The effectiveness of this shunt was studied comparing two groups of 10 rabbits with shunt (S) versus those with clamped portal and inferior caval vein (C). In the group of rabbits that underwent porto-intracaval shunt, the results concerning intraoperative mortality, intraoperative increase in distal portal vein pressure, and incidence of the histologic signs of gut damage were clearly improved. The proposed porto-intracaval shunt was therefore effective in reducing some principal negative effects of portal and caval clamping. This type of porto-intracaval shunt can be therefore useful allowing improvement of experimental models concerning liver surgery in little animals. In chirurgia sperimentale del fegato è difficile prolungare il tempo anepatico dato che gli animali non tollerano un clampaggio portale e cavale prolungato. Gli Autori hanno precedentemente sviluppato un semplice shunt porto-intracavale con l'intento di ovviare alla stasi venosa prolungata. Lo shunt è costituito da un tubo di silicone a forma di Y invertita. Nel presente studio viene analizzata l'efficacia di questo shunt confrontando un gruppo di dieci conigli con shunt (S) rispetto al gruppo sottoposto invece al clampaggio della vena porta e della vena cava inferiore (C). I risultati riguardo mortalità intraoperatoria, incremento intraoperatorio della pressione portale distale e presenza e distribuzione di segni istologici di danno intestinale sono chiaramente migliori nel gruppo con shunt intra-porto cavale. Lo shunt porto-intracavale proposto è risultato realmente efficace nel ridurre alcuni dei principali effetti negativi del clampaggio portale e cavale. Questo tipo di shunt porto-intra cavale può essere quindi utile per migliorare le possibilità e i modelli di chirurgia sperimentale del fegato nei piccoli animali. © 2001 Wiley-Liss, Inc. MICROSURGERY 21:179,182 2001 [source] Intestinal regeneration by a novel surgical procedureBRITISH JOURNAL OF SURGERY (NOW INCLUDES EUROPEAN JOURNAL OF SURGERY), Issue 5 2008S.-C. Jwo Background: Treatment of short bowel syndrome is problematical. Small bowel tissue engineering has achieved modest results in animal studies. The aim of this study was to investigate intestinal regeneration in a novel surgical model. Methods: Roux-en-Y bypass procedures were performed on 40 Wistar rats weighing 250,350 g. Animals were killed at 1, 2, 3, 4, 8, 12 and 24 weeks after implantation with a 3-cm silicone tube. The spatio temporal relationship of intestinal regeneration was analysed using three-dimensional multislice computed tomography, and examination of sequential morphological changes on gross or histological findings and measurement of missing intestinal tissue (growth defects). Results: Progressive intestinal regeneration on a silicone tube was identifiable in 35 animals. Most adhesions were initially localized on the tube but spread to a distal site 4 weeks after implantation. Growth defects decreased with time, with a marked reduction in the first 4 weeks and a gradual reduction to week 24 after implantation. Luminal patency shown radiologically as well as sequential histological findings, such as mucosal lining, matrix remodelling and muscular regeneration, suggested that regeneration of intestinal tissue took place, not merely scar contraction. Conclusion: Non-invasive as well as histomorphological assessment followed intestinal regeneration over time in this model, which provides scope for further studies. Copyright © 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. [source] Bicanalicular double silicone intubation in external dacryocystorhinostomy and canaliculoplasty for distal canalicular obstructionACTA OPHTHALMOLOGICA, Issue 4 2009Sang Won Hwang Abstract. Purpose:, We aimed to evaluate the effectiveness of bicanalicular double silicone intubation in dacryocystorhinostomy (DCR) and canaliculoplasty for distal or common canalicular obstruction. Methods:, We reviewed the medical records of patients with distal or common canalicular obstruction who had undergone bicanalicular double silicone intubation (insertion of two tubes into each canaliculus) during external DCR and canaliculoplasty. We reviewed the records of subjects who had undergone the same surgery with a bicanalicular single intubation as control material. The tubes were removed at around 6 months after surgery. Anatomical and functional success rates of patients who were followed up for > 2 months after the removal of tube(s) were evaluated. In addition, complications related to the silicone tube were evaluated. Results:, Data for 60 eyes of 45 patients in the double-intubation group and 69 eyes of 65 patients in the single-intubation group were retrieved. The double-intubation group showed higher anatomical success rates (96.5%) than the single-intubation group (85.5%). Functional success was achieved by 53 (88.3%) of 60 eyes in the double-intubation group and 56 (81.2%) of 69 eyes in the single-intubation group. There was no significant difference in complication rates between the two groups. Conclusions:, Bicanalicular double silicone intubation for DCR and canaliculoplasty may be an effective mode of treatment for patients with distal or common canalicular obstruction. [source] | ||||||||||