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Sister
Kinds of Sister Terms modified by Sister Selected AbstractsBrother (and Sister), can you spare the S100?JOURNAL OF CUTANEOUS PATHOLOGY, Issue 3 2010Timothy H. McCalmont MD Editor-in-Chief No abstract is available for this article. [source] Russian nurses: from the Tsarist Sister of Mercy to the Soviet comrade nurse: a case study of absence of migration of nursing knowledge and skillsNURSING INQUIRY, Issue 3 2004Elizabeth Murray Nursing in Russia during the Tsarist era had no structure and little formal organisation. The typical nurses of the nineteenth century were ,Sisters of Mercy', working within the communities of the Orthodox Church and semireligious societies, which were formed to provide a military nursing service. The experience of the Crimean War did not stimulate the foundation of an organised nursing service. There was no transfer of this body of nursing knowledge or experience to the wider rural or civilian population. The majority of Russia's population received inadequate medical and little nursing care. [source] Vajra Brother, Vajra Sister: Renunciation, Individualism and the Household in Tibetan Buddhist MonasticismTHE JOURNAL OF THE ROYAL ANTHROPOLOGICAL INSTITUTE, Issue 1 2000Martin A. Mills This article challenges two connected notions in the study of Tibetan Buddhism: that Buddhist monasticism is characterized by a pronounced move towards individualism, systematically detaching monks from relational social life; and that Tibetan Buddhist doctrines of karma represent an alternative mode of identity to those constructed within household life. By comparing the ritual practices and inheritance patterns associated with household groups in Ladakh with tantric ritual forms in local Buddhist (Gelukpa) monasteries, it is argued that they demonstrate pronounced structural similarities, centred on the shared symbolic construct of the household/temple as the source of socialized agency. An analysis of the meditative disciplines of Gelukpa monasticism is used to show how such training serves not to renounce kinship and household values, but to transform them into modes of religious authority, essential to the social position of monks (trapa) and incarnate lamas (tulku) in Tibetan Buddhism. [source] "A World where Action is the Sister of Dream": Surrealism and Anti-capitalism in Contemporary ParisANTIPODE, Issue 5 2004Jill Fenton In discussing the lifestyle and practices of the Paris group of the contemporary surrealist movement, this paper contributes to debates within economic and political geography that seek to develop the imagining of alternatives to neoliberal globalisation through practices of resistance, and spaces of political and policy engagement. The everyday life of the surrealist movement, in combining creativity with progressive choices and radical economic practices that oppose capitalism, while intellectually investigating ideas of revolution, a different society and utopia, suggests a perspective that contributes to the imagining of such alternatives. This paper outlines the deeply embedded nature of surrealist activity in opposing capitalism and illustrates, as one member of the surrealist group suggests, in quoting Baudelaire, surrealism's insistence for a world in which "action is the sister of dream". The paper further contributes to discussion on the role of academics in facilitating spaces of political engagement. [source] Sisters of Magdalen: Women's Mourning in Aemilia Lanyer's Salve Deus Rex JudaeorumENGLISH LITERARY RENAISSANCE, Issue 1 2001PATRICIA PHILLIPPY First page of article [source] Improving Emotion Regulation and Sibling Relationship Quality: The More Fun With Sisters and Brothers Program,FAMILY RELATIONS, Issue 5 2008Denise E. Kennedy Abstract: We examined the role of emotion regulation (ER) in improving sibling relationship quality (SRQ) by evaluating the More Fun With Sisters and Brothers Program where 4- to 8-year-old siblings from 95 families were taught emotional and social competencies. Parents reported on SRQ and ER, and sibling interactions were observed in homes. SRQ and ER improved for program participants (n = 55) in comparison to those in a wait list condition (n = 40). Children participating in the program needed less parental direction to control negative emotions and refrain from directing negative actions toward others following the program. Higher levels of ER were linked with more positive SRQ at posttest. Results highlight the value of strengthening children's emotion regulation processes as a mechanism for promoting prosocial sibling relationships. [source] Scarlett's Sisters: Young Women in the Old South by Anya JabourGENDER & HISTORY, Issue 2 2008MARTHA TOMHAVE BLAUVELT No abstract is available for this article. [source] Selim's Sisters: Muslim Women in Novels by Uwe Timm and Hermann SchulzGERMAN LIFE AND LETTERS, Issue 1 2010Monika Albrecht ABSTRACT Against the backdrop of the fact that German writers with a German background do not seem to be very interested in casting Germans with a migrant background as their literary characters, this paper focuses on two of the rare exceptions that deal with Muslim women of Turkish origin, Uwe Timm's,Rot,(2001) and Hermann Schulz's,Iskender,(1999). In discussing these novels, I am mostly interested in the way these writers take part in current debates on Muslims in Western societies and in how they engage in their specific vision of a multicultural Germany. The results are at least twofold; on the one hand one has to conclude that both Hermann Schulz and Uwe Timm are dividing Muslims into good and bad, desired and not desired; on the other hand their novels also provide facets of a counter image and introduce largely unfamiliar aspects , which can count as a major achievement in the light of the prevailing idea of the Islamic world in the imagination of the German public. Ethnische Minderheiten sind selten in Werken von einheimischen Schriftstellern zu finden. Vor diesem Hintergrund konzentriert sich der vorliegende Essay auf zwei der wenigen Ausnahmen, Uwe Timms Roman,Rot,(2001) and Hermann Schulz',Iskender,(1999), in denen türkisch-muslimische Frauen Teil des literarischen Ensembles sind. Das Interesse gilt insbesondere der Art und Weise, wie ihre Autoren an gegenwärtigen Debatten über Muslime in westlichen Gesellschaften Teil haben, und es wird nach ihrer Vision eines multikulturellen Deutschland gefragt, wie es in den Texten zum Ausdruck kommt. Dabei fällt auf, dass Muslime sowohl bei Hermann Schulz als auch bei Uwe Timm in gute und schlechte, erwünschte und weniger erwünschte aufgeteilt werden. Andererseits entwerfen die Romane jedoch auch Gegenbilder und beziehen Aspekte ein, die der Mehrheit der Deutschen nicht vertraut sind , was angesichts gängiger Vorstellungen über die islamische Lebenswelt als bemerkenswerter Beitrag zur Multikulturalismusdebatte gelten kann. [source] Sisters organising in Japan and Korea: the development of women-only unionsINDUSTRIAL RELATIONS JOURNAL, Issue 3 2007Kaye Broadbent ABSTRACT In this article, I explore the development of women-only unions in Japan and Korea. Women-only unions, which organise women workers across enterprises and employment status boundaries in both countries, have appeared only recently and are new areas of research. While the strategy to form autonomous women-only unions in Japan and Korea is a recent phenomenon, women workers in both countries are continuing a tradition of women's activism that has challenged both management and the male domination of the union movement. By taking a broad scope and by organising the growing non-full-time workforce and women employed in small workplaces, the formation of women-only unions in Japan and Korea is a positive development for both non-unionised women workers and for the broader workers' movement in general. [source] Authority and leadership: the evolution of nursing management in 19th century teaching hospitalsJOURNAL OF NURSING MANAGEMENT, Issue 1 2008CAROL HELMSTADTER BA (Hons), RN (Retd) Aim, This study shows why some 19th century nursing managers were successful and some were not. Background, With the exception of Florence Nightingale, almost nothing has been written about 19th century nursing managers. Method, Classical historical method is used. Extensive use is made of secondary sources. Primary sources are found in the archives of the 12 London teaching hospitals, the Radcliffe Infirmary, the Convents of St John the Divine and the All Saints Sisters, and 16 000 Nightingale documents in the Collected Works of Florence Nightingale. Results, Success in delivering a highly competent nursing service depended on the matron's leadership and legitimate authority but she also had to have the support of her hospital board to gain access to allocation of scarce resources. Implications for nursing management, While the 19th century hospital environment was very different, how nurses directed under different circumstances clarifies our knowledge of successful nursing management in 2007. [source] An encounter between psychology and religion: Humanistic psychology and the Immaculate Heart of Mary nunsJOURNAL OF THE HISTORY OF THE BEHAVIORAL SCIENCES, Issue 4 2005Robert Kugelmann In the 1960s, humanistic psychology changed the relationship between psychology and religion by actively asserting the value of individual experience and self-expression. This was particularly evident in the encounter group movement. Beginning in 1967, Carl Rogers conducted a series of encounter groups, in order to promote "self-directed change in an educational system," for the Sisters of the Immaculate Heart of Mary, a religious order in California running an educational system. William Coulson, one of Rogers's associates in the project, later charged that the encounter groups undermined the religious order and played a major contributing part in the breakup of the order in 1970. The article examines these charges, situating the incident within the context of the changes occurring in religious life and in psychology in the 1960s. The article concludes that an already existing conflict the nuns had with the conservative Cardinal McIntyre of Los Angeles led to the departure of some 300 nuns from the order, who began the Immaculate Heart Community, an organization existing today. Nevertheless, encounter groups proved to be a psychological technology that helped to infuse a modern psychological,specifically, a humanistic psychological,perspective into contemporary religious life. © 2005 Wiley Periodicals, Inc. [source] Russian nurses: from the Tsarist Sister of Mercy to the Soviet comrade nurse: a case study of absence of migration of nursing knowledge and skillsNURSING INQUIRY, Issue 3 2004Elizabeth Murray Nursing in Russia during the Tsarist era had no structure and little formal organisation. The typical nurses of the nineteenth century were ,Sisters of Mercy', working within the communities of the Orthodox Church and semireligious societies, which were formed to provide a military nursing service. The experience of the Crimean War did not stimulate the foundation of an organised nursing service. There was no transfer of this body of nursing knowledge or experience to the wider rural or civilian population. The majority of Russia's population received inadequate medical and little nursing care. [source] Her Name Is "Sisters"THE ECUMENICAL REVIEW, Issue 1 2001Marilia Schüller First page of article [source] Scarlett's Sisters: Young Women in the Old South by Anya JabourTHE JOURNAL OF AMERICAN CULTURE, Issue 3 2007Christopher R. Bloss No abstract is available for this article. [source] ,You can do Nasty Things to your Brothers and Sisters without a Reason': Siblings' Backstage BehaviourCHILDREN & SOCIETY, Issue 5 2008Samantha Punch This article contributes to the recent, but still limited, literature on the sociology of sibship. It argues that during childhood the ambivalent love/hate nature of sibship is played out through the sharing of knowledge, time and space. It draws on the work of Goffman to illustrate that children's sibling interactions tend to consist of backstage, rather than frontstage, performances. The article is based on children's own perspectives from a sample of 90 children aged 5,17 drawn from 30 families of mixed socioeconomic backgrounds in central Scotland. [source] Cerebral palsy in siblings caused by compound heterozygous mutations in the gene encoding protein CDEVELOPMENTAL MEDICINE & CHILD NEUROLOGY, Issue 5 2010CHOONG YI FONG We report two sisters with extensive bilateral periventricular haemorrhagic infarction (PVHI) causing cerebral palsy (CP). The older sister presented at 20 months with cortical visual blindness, spastic diplegia, and purpura fulminans. The younger sister presented aged 3 days old with apnoeas and multifocal seizures. She subsequently had global developmental delay, cortical visual blindness, spastic quadriplegia, epilepsy, and purpura fulminans at age 2 years. Neuroimaging of both siblings showed bilateral PVHI consistent with bilateral cerebral intramedullary venous thrombosis occurring at under 28 weeks' gestation for the older sister and around time of birth for the younger sister. At latest follow-up, the older sister (13y) has spastic diplegia at Gross Motor Function Classification System (GMFCS) level II, and the younger sister (10y) has spastic quadriplegia at GMFCS level IV. Both sisters showed partial quantitative reduction in plasma protein C antigen and severe qualitative reduction in plasma protein C anticoagulant activity. They were heterozygous for two independent mutations in the protein C gene (PROC). There was no other risk factor for CP. To our knowledge, this is the first family reported with compound heterozygous PROC mutations as the likely genetic cause of familial CP. This report adds to the list of known monogenic causes of CP. [source] Polymicrogyria in monozygous twins and an elder siblingDEVELOPMENTAL MEDICINE & CHILD NEUROLOGY, Issue 7 2003Po-Cheng Hung MD Monozygous twin births have been associated with brain lesions such as hydranencephaly, multicystic encephalomalacia, and porencephaly. Prenatal circulatory injury has been considered to be the cause. Polymicrogyria is rare but has been reported in autopsied cases. The sibship in this case report, comprising monozygotic male twins and their elder sister from the same non-consanguineous parents, all had global developmental delay. Brain MRI showed polymicrogyria. We suggest that, apart from circulatory compromise, genetic etiology must be implicated as the cause of polymicrogyria. [source] Autosomal Recessive Idiopathic Epilepsy in an Inbred Family from Turkey: Identification of a Putative Locus on Chromosome 9q32-33EPILEPSIA, Issue 5 2004Betül Baykan Summary: Purpose: The study describes the clinical features of an inbred family from Turkey with three members affected by seizures and tests possible autosomal recessive (AR) inheritance by means of linkage analysis. Methods: Personal and family history was obtained from each subject, and general physical, neurologic, and EEG examinations were performed. A set of 382 fluorescence-labeled markers was used for the initial genome-wide search. A further set of 83 markers was used to map the locus precisely and to exclude the remaining genome. Results: Twelve individuals from three generations were examined. Two subjects were affected by idiopathic epilepsy, whereas, their brother experienced a single unprovoked generalized seizure. Two siblings affected by idiopathic epilepsy and their unaffected sister showed a photoparoxysmal response to photic stimulation. Nine family members reported migraine. The genome-wide search led to the identification of a unique homozygous, 15.1-cM region shared by subjects with seizures on chromosome 9q32-33 and providing a lod score of 2.9. This locus, however, was not associated with migraine in this pedigree. Conclusions: The study suggests that idiopathic epileptic traits with AR inheritance might be underestimated in the general population and that inbred pedigrees may represent powerful tools for the identification of AR genes. [source] Reports of information and support needs of daughters and sisters of women with breast cancerEUROPEAN JOURNAL OF CANCER CARE, Issue 1 2003ASSOCIATE PROFESSOR , K. CHALMERS RN, MSC(A) The aim of this study was to describe the information and support needs of women who have primary relatives with breast cancer. The Information and Support Needs Questionnaire (ISNQ) was developed and revised from previous qualitative and pilot studies. The ISNQ addressed concepts of the importance of, and the degree to which, 29 information and support needs related to breast cancer had been met. The study sample consisted of 261 community-residing women who had mothers, sisters, or a mother and sister(s) with breast cancer. Data were collected using a mailed survey. In addition to the ISNQ, additional items addressed family and health history, breast self-care practices, perception of the impact of the relative's breast cancer and other variables. Also included were established and well-validated measures of anxiety and depression. The findings document women's priority information and support needs. The information need most frequently identified as very important was information about personal risk of breast cancer. Other highly rated needs addressed risk factors for breast cancer and early detection measures. Generally, the women perceived that their information and support needs were not well met. These findings illuminate needs of women for more information and support when they have close family relatives with breast cancer and opportunities for primary care providers to assist women in addressing their needs. [source] PHYLOGENETIC PLACEMENT OF AN UNUSUAL CORAL MUSHROOM CHALLENGES THE CLASSIC HYPOTHESIS OF STRICT COEVOLUTION IN THE APTEROSTIGMA PILOSUM GROUP ANT,FUNGUS MUTUALISMEVOLUTION, Issue 8 2009Bryn T. M. Dentinger The ,50 million-year-old fungus-farming ant mutualism is a classic example of coevolution, involving ants that subsist on asexual, fungal biomass, in turn propagating the fungus clonally through nest-to-nest transmission. Most mutualistic ants cultivate two closely related groups of gilled mushrooms, whereas one small group of ants in the genus Apterostigma cultivates a distantly related lineage comprised of the G2 and G4 groups. The G2 and G4 fungi were previously shown to form a monophyletic group sister to the thread-like coral mushroom family Pterulaceae. Here, we identify an enigmatic coral mushroom that produces both fertile and sterile fruiting structures as the closest free-living relative of the G4 fungi, challenging the monophyly of the Apterostigma -cultivated fungi for the first time. Both nonparametric bootstrap and Bayesian posterior probability support the node leading to the G4 cultivars and a free-living Pterula mushroom. These data suggest three scenarios that contradict the hypothesis of strict coevolution: (1) multiple domestications, (2) escape from domestication, (3) selection of single cultivar lineages from an ancestral mixed-fungus garden. These results illustrate how incomplete phylogenies for coevolved symbionts impede our understanding of the patterns and processes of coevolution. [source] THE PHYLOGENY OF THE PENTASCHISTIS CLADE (DANTHONIOIDEAE, POACEAE) BASED ON CHLOROPLAST DNA, AND THE EVOLUTION AND LOSS OF COMPLEX CHARACTERSEVOLUTION, Issue 4 2007C. Galley We construct a species-level phylogeny for the Pentaschistis clade based on chloroplast DNA, from the following regions: trnL-F, trnT-L, atpB-rbcL, rpL16, and trnD-psbA. The clade comprises 82 species in three genera, Pentaschistis, Pentameris, and Prionanthium. We demonstrate that Prionanthium is nested in Pentaschistis and that this clade is sister to a clade of Pentameris plus Pentaschistis tysonii. Forty-three of the species in the Pentaschistis clade have multicellular glands and we use ancestral character state reconstruction to show that they have been gained twice or possibly once, and lost several times. We suggest that the maintenance, absence, loss, and gain of glands are correlated with leaf anatomy type, and additionally that there is a difference in the degree of diversification of lineages that have these different character combinations. We propose that both glands and sclerophyllous leaves act as defense systems against herbivory, and build a cost/benefit model in which multicellular glands or sclerophyllous leaves are lost when the alternative defense system evolves. We also investigate the association between leaf anatomy type and soil nutrient type on which species grow. There is little phylogenetic constraint in soil nutrient type on members of the Pentaschistis clade, with numerous transitions between oligotrophic and eutrophic soils. However, only orthophyllous-leaved species diversify on eutrophic soils. We suggest that the presence of these glands enables the persistence of orthophyllous lineages and therefore diversification of the Pentaschistis clade on eutrophic as well as oligotrophic soils. [source] SOCIALITY IN THERIDIID SPIDERS: REPEATED ORIGINS OF AN EVOLUTIONARY DEAD ENDEVOLUTION, Issue 11 2006Ingi Agnarsson Abstract Evolutionary ,dead ends' result from traits that are selectively advantageous in the short term but ultimately result in lowered diversification rates of lineages. In spiders, 23 species scattered across eight families share a social system in which individuals live in colonies and cooperate in nest maintenance, prey capture, and brood care. Most of these species are inbred and have highly female-biased sex ratios. Here we show that in Theridiidae this social system originated eight to nine times independently among 11 to 12 species for a remarkable 18 to 19 origins across spiders. In Theridiidae, the origins cluster significantly in one clade marked by a possible preadaptation: extended maternal care. In most derivations, sociality is limited to isolated species: social species are sister to social species only thrice. To examine whether sociality in spiders represents an evolutionary dead end, we develop a test that compares the observed phylogenetic isolation of social species to the simulated evolution of social and non-social clades under equal diversification rates, and find that sociality in Theridiidae is significantly isolated. Because social clades are not in general smaller than their nonsocial sister clades, the spindly phylogenetic pattern,many tiny replicate social clades,may be explained by extinction rapid enough that a nonsocial sister group does not have time to diversify while the social lineage remains extant. In this case, this repeated origin and extinction of sociality suggests a conflict between the short-term benefits and long-term costs of inbred sociality. Although benefits of group living may initially outweigh costs of inbreeding (hence the replicate origins), in the long run the subdivision of the populations in relatively small and highly inbred colony lineages may result in higher extinction, thus an evolutionary dead end. [source] Relationships in Taraxacum section Arctica s.l. (Asteraceae, Cichorieae) and allies based on nrITSFEDDES REPERTORIUM, Issue 1-2 2009I. Uhlemann nrITS sequences of 19 Taraxacum -species as well as four outgroups of Asteraceae-Cichorieae were analysed using Bayesian and parsimony analyses in order to establish their systematics. The Arctica s.l. clade together with T. bessarabicum is sister to all derived European and South American taxa. The division of Arctica s.l. into smaller units (sections: Antarctica, Arctica s. str., Australasica) is supported. Within the remaining taxa, Taraxacum farellonicum, a species from the Chilean Andes which is described as new, is supposed to be a hybrid of T. gilliesii and an introduced Ruderalia -species. Section Erythrosperma is well separated and supported. With the exception of T. patagonicum and T. bracteatum which are sister to the other representatives of the European taxa two groups are distinguished: first the Ruderalia/Hamata alliance (including T. tenebricans with some exceptional characters) of predominantly ruderal species and second an assemblage of the sections Celtica, Fontana, Macrodonta, Palustria and Taraxacum prefering a lesser ruderal habitate. (© 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) Molekulare Systematik der Gattung Taraxacum Sektion Arctica s.l. (Asteraceae, Cichorieae) und verwandter Arten auf der Basis von nuklearer ribosomaler DNA (nrITS) Die Verwandtschaftsverhältnisse von 19 Arten der Gattung Taraxacum und vier Außengruppen aus den Asteraceae-Cichorieae wurden mit Bayesischen und Parsimonieanalysen der nrITS Sequenzen rekonstruiert. Die Sektion Arctica s.l. bildet zusammen mit T. bessarabicum die Schwestergruppe zu den abgeleiteten europäischen und südamerikanischen Taxa. Die Klassifizierung der Arctica s.l. in die Sektionen Antarctica, Arctica s.str. und Australasica wird von den Analysen unterstützt. Die in dieser Studie neu beschriebene Art, Taraxacum farellonicum, aus den chilenischen Anden ist wahrscheinlich ein Hybrid aus T. gilliesii und einer neophytischen Art der Sektion Ruderalia. Die Sektion Erythrosperma erscheint als gut gestützte Gruppe. Mit Ausnahme von T. patagonicum und T. bracteatum, die Schwestergruppen zu den anderen Vertretern europäischer Taxa bilden, können zwei größere Komplexe unterschieden werden: erstens die Ruderalia/Hamata -Gruppe (einschließlich T. tenebricans mit einigen besonderen Merkmalen), welche vorwiegend Arten der ruderalen Standorte umfasst und zweitens ein Verwandtschaftskreis aus den Sektionen Celtica, Fontana, Macrodonta, Palustria und Taraxacum, die an weniger stark ruderalisierten Standorten vorkommen. [source] Sir Francis Knollys's Latin dictionary: new evidence for Katherine Carey*HISTORICAL RESEARCH, Issue 209 2007Sally Varlow A Latin dictionary once owned by Sir Francis Knollys has come to light containing his records of his marriage to Katherine Carey, daughter of Mary Boleyn, and the births of their fourteen children. These previously unpublished details (here transcribed) strengthen the argument that Katherine was an illegitimate child of Henry VIII, born during his affair with Anne Boleyn's sister. Sir Francis's handwritten notes also reveal his wife's remarkably successful series of pregnancies; and the birth date of his daughter Lettice , branded a ,she-wolf' by Elizabeth I , who turns out to be younger than is usually claimed when she married Robert Dudley, earl of Leicester. [source] The Kingdom of Sicily and the Kingdom of England, 1066,1266HISTORY, Issue 292 2003G. A. Loud This article looks back from the political crisis in England in the 1250s to examine English and Anglo-Norman perceptions of southern Italy and Sicily, and contacts between the two regions, over the previous two centuries. Although some at least were conscious of a common Norman heritage, commentators from England knew relatively little of the southern kingdom; certainly less than the Norman chroniclers, Orderic Vitalis and Robert of Torigni, and even they were less well informed than has been suggested in the past. There was a period of increased diplomatic contact for a generation or so after 1160, in which the Becket dispute played a part, culminating in the visit of Richard I to Sicily during the Third Crusade although that episode did nothing to increase the warmth of Anglo-Sicilian relations. Thereafter there was relatively little contact for the next half-century, in spite of Frederick II's marriage to the sister of Henry III of England in 1235. Furthermore, Sicily was always perceived as an exotic and alien region indicating that the perceptions found in the 1250s had been anticipated at an earlier period. [source] Hereditary benign telangiectasia: first case in IranINTERNATIONAL JOURNAL OF DERMATOLOGY, Issue 7 2006Zari Javidi A 14-year-old boy was referred to the Dermatology Clinic of the Medical University of Mashhad, Iran, with numerous cutaneous telangiectasias on the face, ears, lips, and back of the hands, with lesions in the temporal region being the first to appear (Figs 1,3). His mother stated that the lesions had been present for 10 years with an increase in the past 6 months. He had no history of bleeding from the nose, mouth, gastrointestinal tract, and other mucosal surfaces, and there was no sign of organ involvement. On inspection, no lesions were detected on the nasal mucosa, external ear, over the tympanic membrane, or mouth. Figure 1. Numerous telangiectasias affecting the cheeks, nose, and perioral areas Figure 2. Lateral view of Fig. 1 Figure 3. Telangiectasias affecting the dorsal aspect of the hands The patient is one member of a family of six. His mother is healthy, but similar lesions were seen in his father, sister and one of his brothers with similar distributions. Lesions were also seen in his aunt and paternal grandmother, showing disease distribution in six members of this family from three generations. The oldest brother is 20 years of age and mentioned the onset of disease from the age of 10 years. The sister is 18 years of age and lesions started to appear 7 years ago; she claims that the lesions regress during her menstrual period. The youngest brother is 4 years of age and shows no sign of cutaneous lesions as yet. The parents are not consanguineous. Generalized telangiectasia with a predominant distribution on light-exposed skin, an autosomal dominant inheritance, and no sign of systemic or mucosal involvement and bleeding disorders indicates a diagnosis of hereditary benign telangiectasia. Our patient did not consent to biopsy. [source] Compound heterozygosity in sibling patients with recessive dystrophic epidermolysis bullosa associated with a mild phenotypeINTERNATIONAL JOURNAL OF DERMATOLOGY, Issue 3 2006Y. Shibusawa MD We describe two cases of a 3-year-old Japanese boy and his 1-year-old sister presenting recessive dystrophic epidermolysis bullosa; a relatively mild phenotype. Blistering and scarring were limited to the acral region, and some fingernails and toenails were lost. PCR-RFLP and DNA sequencing analyses revealed compound heterozygotes for a splice-site mutation (6573 +1GtoC) and a nonsense mutation (E2857X) in the type VII collagen gene (COL7A1). Both mutations caused a premature termination codon (PTC). The mutation E2857X was located behind the candidate cleavage site within the NC-2 domain required for the assembly of anchoring fibrils. This PTC position may explain their mild phenotype. [source] A unique variant of Darier's diseaseINTERNATIONAL JOURNAL OF DERMATOLOGY, Issue 4 2001Christopher M. Peterson MD A 45-year-old black woman presented with a chief complaint of an increasing number of ,,light spots'' on her face, upper trunk, and legs. She had a 4-year history of a pruritic eruption on the dorsum of her hands. The eruption was particularly pruritic in the summer months. Other family members, including her sister and her daughters, reportedly had a similar dermatologic problem. The patient had been previously evaluated and biopsied by another dermatologist. The earlier biopsy was nondiagnostic, however, and she presented for further evaluation of this problem. On physical examination, the patient had hypopigmented macules along her jawline (Fig. 1), lateral neck, and upper chest. She had similar hypopigmented macules on her thighs. She had hyperkeratosis of the palmoplantar surface of her hands and feet. The dorsum of her hands had numerous coalescing, shiny, flat-topped, hypopigmented papules (Fig. 2), and several of her fingernails had distal, V-shaped notching. Figure 1. Hypopigmented macules on the cheek and along the jawline Figure 2. Coalescing, hypopigmented papules on the dorsal aspect of the fingers and hand, with distal notching of the fingernails A punch biopsy from a papule on the dorsum of her hand was obtained. The epidermis had corps ronds present with focal areas of acantholysis above the basal layer (Fig. 3). The dermis had sparse, superficial, perivascular infiltrates composed of lymphocytes and histiocytes. These changes were consistent with our clinical diagnosis of Darier's disease (keratosis follicularis). Figure 3. Corps ronds (large arrow) and focal acantholysis with suprabasal clefts (small arrow) are present in the epidermis (hematoxylin and eosin; original magnification, ×,40) [source] Other financial corporations: Cinderella or ugly sister of empirical monetary economics?INTERNATIONAL JOURNAL OF FINANCE & ECONOMICS, Issue 1 2005K. Alec Chrystal Abstract This paper reports estimates of an econometric model of the determinants of OFCs' broad money holding and M4 lending to OFCs. This is of interest both as providing information about a component of UK money and credit aggregates and because it provides some evidence of the link between financial activity and growth of the real economy. We model the long-run equilibria for money holding and lending to this sector as being driven by GDP, wealth, the return to financial services and various interest spreads. The dynamics of OFCs' money and lending are shown to be interdependent. We then consider the evidence for interactions between OFCs and other sectors. Our results indicate that M4 lending to OFCs is significantly related to aggregate investment in the long run, but is largely unrelated to the spending of households. Copyright © 2005 John Wiley & Sons, Ltd. [source] Cotylea (Polycladida): a cladistic analysis of morphologyINVERTEBRATE BIOLOGY, Issue 2 2008Kate A. Rawlinson Abstract. Polyclad flatworms are acoelomate bilaterians found in benthic communities worldwide, predominantly in marine environments. Current polyclad systematics is unstable, with two non-concordant classification schemes resulting in a poor understanding of within-group relationships. Here we present the first phylogenetic framework for the suborder Cotylea using a morphological matrix. Representatives of 34 genera distributed among all cotylean families (except four, excluded due to their dubious taxonomic status) were investigated. The number of families included ranges from a conservative eight to a revisionary 11. Outgroup analysis indicated that the suborder is monophyletic and defined by the presence of a ventral adhesive structure, a short posteriorly positioned vagina, and cement glands. Of the eight to 11 families included, we confirmed that three were monophyletic: Boniniidae, Prosthiostomidae, and Pseudocerotidae. Boniniidae was consistently recovered as the sister group to other Cotylea, based on the retention of the plesiomorphic Lang's vesicle. The clade consisting of Anonymus, Marcusia, and Pericelis is sister to the Boniniidae and the rest of the Cotylea. Above this clade there is little resolution at the base of the sister group. The Euryleptidae are found to be paraphyletic and give rise to the Pseudocerotidae. Neither classification scheme received unequivocal support. The intrafamilial relationships of the diverse Pseudocerotidae and Euryleptidae were examined. Color pattern characters (used for species identification) were highly homoplasious but increased cladogram resolution within genera. The monophyly of seven genera within the Pseudocerotidae and Euryleptidae was not supported and many genera showed no autapomorphies, highlighting the need for taxonomic revision of these families. [source] | ||||||||||||||||||||||||||||||||||||||||||||||