Home About us Contact
|
Home About us Contact | ||
|
|
||
Sinus Thrombosis (sinus + thrombosis)
Kinds of Sinus Thrombosis Selected Abstracts,Sagittal sinus thrombosis in a teenager: homocystinuria associated with reversible antithrombin deficiency'DEVELOPMENTAL MEDICINE & CHILD NEUROLOGY, Issue 7 2002Ewoud Vorstman Specialist Registrar Paediatrics No abstract is available for this article. [source] Interobserver agreement in the magnetic resonance location of cerebral vein and dural sinus thrombosisEUROPEAN JOURNAL OF NEUROLOGY, Issue 3 2007J. M. Ferro The interobserver variation in the magnetic resonance (MR) location of cerebral vein and dural sinus thrombosis (CVT) has not been previously reported. Four independent observers rated a convenience sample of 40 MR/MR angiographies to assess whether or not each dural sinus and major cerebral veins were occluded. Interobserver reliability was measured using , statistics. Interobserver agreement was comparable between the six pairs of raters. Agreement was excellent for thrombosis of the deep cerebral venous system (, = 1.00), cerebellar veins (, = 1.00), superior saggital sinus (, range: 0.82,1) and right jugular vein (, range: 0.84,0.95); good to excellent for the right transverse/sigmoid sinus (, range: 0.75,0.90) and the left jugular vein (, range: 0.65,0.85); moderate to excellent for the left lateral sinus (, range: 0.59,0.78) and the straight sinus (, range: 0.59,0.92); poor to good for the cortical veins (, range: 0.02,0.65). Agreement between observers varies with the location of CVT. It is good or excellent for most of the occluded sinus and veins, except for the cortical veins. This study suggests that information on the location of CVT can be reliably collected and used in multicentre studies. [source] EFNS guideline on the treatment of cerebral venous and sinus thrombosisEUROPEAN JOURNAL OF NEUROLOGY, Issue 6 2006K. Einhäupl Cerebral venous and sinus thrombosis (CVST) is a rather rare disease which accounts for <1% of all strokes. Diagnosis is still frequently overlooked or delayed due to the wide spectrum of clinical symptoms and the often subacute or lingering onset. Current therapeutic measures which are used in clinical practice include the use of anticoagulants such as dose-adjusted intravenous heparin or body weight-adjusted subcutaneous low-molecular-weight heparin (LMWH), the use of thrombolysis, and symptomatic therapy including control of seizures and elevated intracranial pressure. We searched MEDLINE (National Library of Medicine), the Cochrane Central Register of Controlled Trials (CENTRAL) and the Cochrane Library to review the strength of evidence to support these interventions and the preparation of recommendations on the therapy of CVST based on the best available evidence. Review articles and book chapters were also included. Recommendations were reached by consensus. Where there was a lack of evidence, but consensus was clear we stated our opinion as good practice points. Patients with CVST without contraindications for anticoagulation should be treated either with body weight-adjusted subcutaneous LMWH or dose-adjusted intravenous heparin (good practice point). Concomitant intracranial haemorrhage related to CVST is not a contraindication for heparin therapy. The optimal duration of oral anticoagulation after the acute phase is unclear. Oral anticoagulation may be given for 3 months if CVST was secondary to a transient risk factor, for 6,12 months in patients with idiopathic CVST and in those with ,mild' hereditary thrombophilia. Indefinite anticoagulation (AC) should be considered in patients with two or more episodes of CVST and in those with one episode of CVST and ,severe' hereditary thrombophilia (good practice point). There is insufficient evidence to support the use of either systemic or local thrombolysis in patients with CVST. If patients deteriorate despite adequate anticoagulation and other causes of deterioration have been ruled out, thrombolysis may be a therapeutic option in selected cases, possibly in those without intracranial haemorrhage (good practice point). There are no controlled data about the risks and benefits of certain therapeutic measures to reduce an elevated intracranial pressure (with brain displacement) in patients with severe CVST. Antioedema treatment (including hyperventilation, osmotic diuretics and craniectomy) should be used as life saving interventions (good practice point). [source] Transverse Sinus Thrombosis Presenting With Acute Hydrocephalus: A Case ReportHEADACHE, Issue 2 2008Lampis C. Stavrinou MD We report on a 32-year-old woman who presented with headache of a 10-day duration, due to acute hydrocephalus. This was a result of a tumefactive lesion of the posterior fossa, which was later proven to be a cerebellar venous infarct caused by unilateral transverse sinus thrombosis. Cerebral dural sinus thrombosis should be considered in the differential diagnosis of new onset of headache. [source] Unilateral Orbital Bruit in an Adolescent With Daily Persistent HeadacheHEADACHE, Issue 2 2006Todd D. Rozen MD The presence of an orbital bruit in a patient with daily headache suggests an underlying secondary cause. A case is presented in which a unilateral orbital bruit appeared to be the only physical sign of a dural venous sinus thrombosis. [source] Utility of D-dimer in the diagnosis of cerebral venous sinus thrombosisJOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 2 2005B. CUCCHIARA [source] Conservative treatment of L -asparaginase-associated lipid abnormalities in children with acute lymphoblastic leukemia,PEDIATRIC BLOOD & CANCER, Issue 5 2010Hofit Cohen MD Abstract Objective To determine the incidence and clinical consequences of asparaginase-associated lipid abnormalities in children with acute lymphoblastic leukemia (ALL). Methods Sixty-five newly diagnosed children and adolescents aged 0.4,21 years with ALL or lymphoblastic lymphoma were retrospectively evaluated for lipid abnormalities. They were treated according to the ALLIC-BFM 2002 protocol between 2002 and 2005. Fasting cholesterol levels were measured in all patients and triglycerides (TG) in 42/65 patients. Results Prior to treatment, mean cholesterol level was 149,±,50,mg/dl, and increased to maximal level 274,±,124,mg/dl during treatment. Mean TG level during treatment was 459,±,526,mg/dl (range 54,3,009). Twelve patients (28%) had TG levels <200,mg/dl, 18 (43%) had 200,400,mg/dl, 3 (7%) had 400,600,mg/dl, 4 (10%) between 600 and 1,000,mg/dl, and 5 (12%) patients had >1,000,mg/dl. No association was found between TG levels and age or gender. One of the 12 patients with TG >400,mg/dl developed left saggital sinus thrombosis and left frontal lobe infarct. TG level at the time of the event was 2,640,mg/dl. None of the five patients with TG levels >1,000,mg/dl developed pancreatitis. Children with TG levels between 400 and 600,mg/dl were treated by fasting. Fibrates and heparin were added to those with levels >600,mg/dl. Lipid abnormalities normalized in all children upon completion of asparaginase treatment. Conclusions Abnormalities of lipid profile in children with ALL during asparaginase therapy are relatively common. We recommend measuring TG before and during asparaginase treatment. Initiation of conservative treatment could prevent further increase of TG and decrease the risk of potential complications. Pediatr Blood Cancer 2010;54:703,706. © 2010 Wiley-Liss, Inc. [source] Cerebral venous sinus thrombosis in an infant with Pseudomonas aeruginosa sepsisPEDIATRICS INTERNATIONAL, Issue 2 2010Chang-Hung Kuo No abstract is available for this article. [source] Prenatal diagnosis of a spontaneous dural sinus thrombosisPRENATAL DIAGNOSIS, Issue 8 2009G. Legendre First page of article [source] Saka, an ancestral possession: MalaysiaASIA-PACIFIC PSYCHIATRY, Issue 3 2010Hasanah Che Ismail MBBS MPM Abstract This report illustrates a culture-bound disorder known as "saka" in the local population of Kelantan, as well as other states in Malaysia. It is a form of possession by the spirit of a deceased ancestor who was once a traditional healer or shaman. While in a dissociative state, the patient introduced a 7 × 3,4 cm wooden stick precisely into his inferior rectus muscle, in an attempt to identify with a blind ancestor who showed his presence momentarily and specifically to the patient. The stick remained hidden to ophthalmologists for 17 days and during this period the patient developed right orbital cellulitis, bilateral cavernous sinus thrombosis and sepsis. The stick was identified after the family took the patient home for cultural healing rites to be performed. The patient's altered behavior resolved with the removal of the stick and he returned to his premorbid personality and functioning without psychotropic medication. To date, saka has not been reported in any peer-reviewed medical journal. [source] Recurrent dural venous sinus thrombosis in a 20-year-old man: nature or nurture?BRITISH JOURNAL OF HAEMATOLOGY, Issue 4 2009Ceri Marrin No abstract is available for this article. [source] Hormonal contraceptives as a risk factor for cerebral venous and sinus thrombosisACTA NEUROLOGICA SCANDINAVICA, Issue 5 2007M. Saadatnia This review will focus on recent developments in our understanding of cerebral venous and sinus thrombosis (CVST), as a side effect of combined oral contraceptives (COCs) use. Case,control studies have shown an increased risk of CVST in women who use COCs, especially third-generation contraceptives that contain gestodene or desogestrel. Several studies have indicated that the combination of COCs and thrombophilia greatly increased the risk of CVST, particularly in women with hyperhomocysteinaemia, factor V Leiden and the prothrombin-gene mutation. Women with thrombophilia who developed CVST while taking oral contraceptives should be definitively advised to stop using COCs. These patients should be considered for preventive therapy with low doses of heparin in prothrombotic situations such as bed rest or pregnancy, and the duration of anticoagulation should be considered on a case-by-case basis. Patients may be considered candidates for chronic treatment with antiplatelet agents. The best and most cost-effective screening method for thrombophilia in women who are planning to conceive is selective screening based on the presence of previous personal or family history of either prior extracerebral or cerebral venous thromboembolism events. [source] Arterial contamination: a useful indirect sign of cerebral sino-venous thrombosisACTA NEUROLOGICA SCANDINAVICA, Issue 2 2006R. Kochhar Background,,, Various imaging findings of cerebral sino-venous thrombosis (CSVT) have been described on magnetic resonance venography (MRV). Objective,,, The purpose of this study was to evaluate the significance of visualization of the arterial system on cerebral MRV, also described as arterial contamination, as an indirect sign of CSVT. Methods,,, Forty patients with a clinical suspicion of venous sinus thrombosis underwent MR imaging of the brain, followed by MRV sequence, based on 2D time of flight technique in the coronal oblique plane. Patient's clinical symptoms and signs were noted with particular interest for papilloedema. Twenty-seven patients were diagnosed to have cerebral venous thrombosis on MRV, and of these, arterial contamination was visualized in 16 patients. In the remaining 13 cases, in which there was no evidence of venous sinus thrombosis, arterial contamination was absent. The sensitivity of this finding was 59.25% (n = 16/27), specificity was 100%, positive predictive value was 100% and negative predictive value was 54.2%. Of these 16 patients with arterial contamination, 12 patients had evidence of increased intracranial pressure in the form of papilloedema. Conclusion,,, Visualization of the arterial system is a useful indirect sign of CSVT, and may be an indicator of increased intracranial pressure in these patients. [source] Cerebral venous sinus thrombosis manifesting as bilateral subdural effusionACTA NEUROLOGICA SCANDINAVICA, Issue 6 2004G. Marquardt Three patients with bilateral subdural effusion, an exclusive manifestation of cerebral venous sinus thrombosis (CVST), are presented. A possible explanation of this rare occurrence is provided, and the differential therapeutic strategies are discussed. We propose to consider CVST in cases of subdural effusions of obscure origin. Appropriate imaging studies should not be delayed if there is suspicion of sinus thrombosis to enable adequate therapy to be started as soon as possible. [source] | ||||||||||