Home About us Contact
|
Home About us Contact | ||
|
|
||
Severe Periodontal Disease (severe + periodontal_disease)
Selected AbstractsPeriodontal conditions in patients with coronary heart disease: a case,control studyJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 3 2008Carin Starkhammar Johansson Abstract Aim: This study examined periodontal conditions in patients with coronary heart disease (CHD) and subjects with no history of CHD. Material and Methods: Participants were 161 patients (40,75) with severe angina pectoris (diagnosed as CHD by coronary angiography) who subsequently underwent percutaneous coronary intervention and 162 control subjects with no history of CHD. Periodontal status was recorded. Bone loss was determined on radiographs. Periodontal disease experience was classified into five groups according to Hugoson & Jordan. Results: Periodontal disease experience groups 4 and 5 were more common in the CHD group (25%) compared with the control group (8%). The mean bone level (the distance from the CEJ to the most coronal level of the alveolar bone) was 3.0±1.0 mm in CHD subjects and 2.6±0.8 mm in controls. CHD patients had significantly lower numbers of natural teeth, higher numbers of periodontal pockets 4,6-mm and higher bleeding on probing (%). In a stepwise regression analysis, the factor periodontal disease experience groups 4+5 gave an odds ratio of 5.74 (2.07,15.90) for having CHD after controlling for smoking and age. Conclusion: Severe periodontal disease expressed by several clinical and radiographic parameters was more prevalent among subjects with CHD than among controls. Analysis, the factor periodontal disease experience groups 4+5 gave an odds ratio of 5.74 (2.07,15.90) for having CHD after controlling for smoking and age. [source] Women with a recent history of early-onset pre-eclampsia have a worse periodontal conditionJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 3 2007Alina Kunnen Abstract Objective: Pre-eclampsia is a complication of pregnancy characterized by systemic vascular dysfunction and pathological changes in placental arteries. Growing evidence of chronic infection as an aetiological factor in vascular diseases prompted us to study maternal periodontal disease in subjects with early-onset pre-eclampsia (<34 weeks). Methods: A case,control study was carried out on 17 early-onset pre-eclamptic women and 35 controls with uncomplicated pregnancies in a period of 3,28 months postpartum. All were Caucasians. Full-mouth periodontal examinations were performed to determine the periodontal condition. Subgingival-plaque samples were analysed by anaerobic culture techniques for the presence of seven bacterial periodontal pathogens. Potential confounders as age, smoking, educational level and body mass index were determined. Results: Severe periodontal disease was found in 82% of the pre-eclamptic and in 37% of the control group (p=0.009). After adjusting for age, smoking and educational level, the odds ratio was 7.9 (95% CI: 1.9,32.8). The periodontopathic microorganism Micromonas micros was more prevalent in the case group (p=0.040) while Campylobacter rectus was more prevalent in the control group (p=0.047). Conclusion: These results indicate that Caucasian women with a recent history of early-onset pre-eclampsia have a worse periodontal condition, as compared with women with uncomplicated deliveries. [source] Substance use and periodontal disease among Australian Aboriginal young adultsADDICTION, Issue 4 2010Lisa M. Jamieson ABSTRACT Aim To investigate the effects of tobacco, marijuana, alcohol and petrol sniffing on periodontal disease among Australian Aboriginal young adults. Design Cross-sectional nested within a long-standing prospective longitudinal study. Setting Aboriginal communities in Australia's Northern Territory. Participants Members of the Aboriginal Birth Cohort study who were recruited from birth between January 1987 and March 1990 at the Royal Darwin Hospital, Northern Territory, Australia. Data were from wave III, when the mean age of participants was 18 years. Measurements Clinical dental examination and self-report questionnaire. Findings Of 425 participants with complete data, 26.6% had moderate/severe periodontal disease. There was elevated risk of periodontal disease associated with tobacco [prevalence ratio (PR) = 1.59, 95% CI = 1.06,2.40], marijuana (PR = 1.44, 95% CI = 1.05,1.97) and petrol sniffing (PR = 1.83, 95% CI = 1.08,3.11), but not alcohol (PR = 0.92, 95% CI = 0.67,1.27). Stratified analysis showed that the effect of marijuana persisted among tobacco users (PR = 1.47, 95% CI 1.03,2.11). It was not possible to isolate an independent effect of petrol sniffing because all petrol sniffers used both marijuana and tobacco, although among smokers of both substances, petrol sniffing was associated with an 11.8% increased prevalence of periodontal disease. Conclusions This is the first time that substance use has been linked with periodontal disease in a young Australian Aboriginal adult population, and the first time that petrol sniffing has been linked with periodontal disease in any population. The role of substance use in periodontal disease among this, and other, marginalized groups warrants further investigation. [source] IL-6,174 genotype associated with the extent of periodontal disease in type 1 diabetic subjectsJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 1 2009Taina Raunio Abstract Aim: The aim of this study was to investigate whether genetic polymorphism in certain cytokine and receptor molecule genes and diabetic status associate with the extent of periodontal disease in type 1 diabetes mellitus (DM). Material and Methods: Eighty patients with type 1 DM participated. Visible plaque, bleeding on probing (BOP), probing pocket depth (PD) and attachment level (AL) were examined clinically and glycosylated haemoglobin (HbA1c) levels were used to assess the glycemic control of DM. CD-14, IL-6, TNF- ,, IL-10, IL-1,, IL-1, and TLR-4 gene polymorphisms were studied using the polymerase chain reaction (PCR). Results: The 3-year HbA1c was good (<7.5%) in 16%, acceptable (7.5,8.5%) in 36% and poor (>8.5%) in 48% of the subjects. IL-6,174 genotype and 3-year GHbA1c associated significantly with BOP and PD4 mm, subjects with the GG genotype of the IL-6,174 exhibiting more severe periodontal disease than those with the GC/CC genotype. After stratification by IL-6 genotype, associations between the extent of periodontal disease and 3-year HbA1c levels remained significant in subjects carrying the GC/CC but not the GG genotype. Conclusions: In addition to the HbA1c level, the IL-6,174 genotype is a significant susceptibility factor for periodontal disease among type 1 diabetics. [source] The extent of periodontal disease and the IL-6,174 genotype as determinants of serum IL-6 levelJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 12 2007Taina Raunio Abstract Aim: To study the extent of periodontal disease and the IL-6,174 genotype as determinants of serum and mouthwash IL-6 concentration in subjects with moderate to severe periodontal disease. Material and Methods: Fifty-two generally healthy subjects volunteered to participate. Probing pocket depth (PD) and periodontal attachment level (AL) were clinically examined and alveolar bone level (BL) was measured on orthopantomographs. IL-6 concentrations in mouthwash, collected by rinsing with 3 ml saline for 30 s and in serum, obtained by venipuncture, were measured using ELISA. IL-6,174 polymorphism was studied using a polymerase chain reaction. Results: Eleven subjects carried the GG genotype, and 41 subjects, carried the CG/CC genotype. The mean (± SD) concentration of IL-6 in serum was 1.6 (± 1.5) pg/ml and, 2.8 (± 5.04) pg/ml in mouthwash. The serum concentration of IL-6 was higher in subjects with the GG genotype than with the CG/CC genotype. In regression analyses the percentages of sites with PD6 mm, AL6 mm and BL8 mm, the IL-6,174 genotype, body mass index and gender associated significantly with serum IL-6 concentration. Conclusions: The extent of moderate to severe periodontal disease and the IL-6,174 genotype contribute significantly to serum IL-6 concentration. [source] The relationship of some negative events and psychological factors to periodontal disease in an adult Swedish population 50 to 80 years of ageJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 3 2002A. Hugoson Abstract Background: Clinical observations and epidemiological studies suggest that experiences of negative life events, especially those manifested as depression, may contribute to an increased susceptibility to periodontal disease. Objective: In the present study, the prevalence of some negative life events and psychological factors and their relation to periodontal disease were investigated. The sample consisted of individuals 50,80 years of age from an extensive cross-sectional epidemiological study performed in 1993 in the city of Jönköping, Sweden. Method: 298 dentate individuals from the Jönköping study were randomly selected. Clinical and radiographic examinations included registration of the number of existing teeth, plaque index, gingival index, pocket depth, and alveolar bone loss. In addition, a questionnaire about socioeconomic status, life events, and psychological and stress-related factors was used. Results: The results revealed that, in addition to the well-documented periodontal disease risk factors such as increased age, oral hygiene status, and smoking, the loss of a spouse (being a widow or widower) and the personality trait of exercising extreme external control were also associated with severe periodontal disease. Conclusion: The findings support recent studies suggesting that traumatic life events such as the loss of a spouse may increase the risk for periodontal disease. Above all, the present results indicate that an individual's ability to cope with stressful stimuli (coping behavior), as measured by the beliefs of locus of control of reinforcements may play a role in the progression of periodontal disease. Zusammenfassung Hintergrund: Klinische Beobachtungen und epidemiologische Studien legen den Schluss nahe, dass negative Ereignisse im Laufe des Lebens, insbesondere solche, die sich in Depression manifestieren, zu einer erhöhten Empfänglichkeit für Parodontitis beitragen. Zielsetzung: Untersuchung der Prävalenz von negativen Ereignissen im Lebenslauf sowie psychologischen Faktoren und deren Beziehung zu Parodontalerkrankungen in einer Population im Alter zwischen 50 und 80 Jahren, die im Rahmen einer extensiven epidemiologischen Querschnittsstudie im Jahre 1993 in der Stadt Jönköping in Schweden untersucht worden war. Material und Methoden: 298 bezahnte Personen wurden randomisiert aus der Jönköping-Studie ausgewählt. Die klinischen und röntgenologischen Untersuchungen umfassten die Erhebung der vorhandenen Zähne, der Plaque Index, Gingival Index, Sondierungstiefen und alveolärem Knochenabbau. Zusätzlich wurden durch Befragung sozioökonomischer Status, Lebensereignisse sowie psychologische und stressbezogene Faktoren erfasst. Ergebnisse: Die Resultate ergaben, dass zusätzlich zu den bekannten Parodontitisrisikofaktoren wit Alter, Mundhygienestatus und Rauchen der Verlust des Ehepartners, also eine Witwe oder ein Witwer zu sein, und das Persönlichkeitsmuster extreme externe Kontrolle auszuüben, mit schwerer Parodontitis assoziiert waren. Schlussfolgerungn: Diese Ergebnisse unterstützen neuere Studien, die Hinweise dafür gegeben haben, dass traumatische Lebensereignisse wie der Verlust eines Ehenpartners das Risiko an Parodontitis zu erkranken erhöhen. Darüber hinaus legen die Ergebnisse den Schluss nahe, dass die individuelle Fähigkeit mit Stress umzugehen (Coping), die in dieser Studie durch die Erfragung der Überzeugung über die Lokalisation der Kontrolle von Verstärkungen erfasst wurde, eine Rolle in der Progression der Parodontitis spielen. Résumé Origine: Des observations cliniques et des études épidémiologiques suggèrent que des évènements négatifs, particulièrement ceux manifestés par une dépression, puisse contribuer à une susceptibilité augmentée à la maladie parodontale. But: Dans cette étude, la prévalence de ces évènements négatifs et les facteurs psychologiques et leurs relations avec la maladie parodontale ont été recherchés. L'échantillon était composé de personnes âgées de 50 à 80 ans issues d'une étude épidémiologique extensive croisée réalisé en 1993 dans la ville de Jonkoping en Suède. Méthode: 298 individus dentés de cette étude furent sélectionnés au hasard. Les examens cliniques et radiographiques comprenaient l'enregistrement du nombre de dents présentes, l'indice de plaque, l'indice gingival, la profondeur de poche et la perte osseuse alvéolaire. De plus, un questionnaire sur le statut socio économique, les évènements de la vie et les facteurs psychologiques en relation avec le stress, fut utilisé. Résultats: Les résultats montrèrent qu'en plus des facteurs de risque bien documentés de maladie parodontale comme l'âge, l'hygiène orale et le tabagisme, la perte d'un époux (que l'on soit veuf ou veuve) et le trait de personnalité de pouvoir exercer un contrôle externe extrême étaient aussi associés avec une maladie parodontale sévère. Conclusion: Ces résultats soutiennent de récentes études qui suggèrent que des évènements traumatisant de la vie quotidienne comme la perte d'un époux puisse augmenter le risque pour la maladie parodontale. Par-dessus tout, ces résultats indiquent que la capacité d'un individu à gérer des stimuli stressants, (comportement gestionnel), mesurés par les convictions de contrôle des renforcements pourrait jouer un rôle dans la progression de la maladie parodontale. [source] The outcome of a preventive dental care programme on the prevalence of localized aggressive periodontitis in Down's syndrome individualsJOURNAL OF INTELLECTUAL DISABILITY RESEARCH, Issue 7 2006M. Zigmond Abstract Background Periodontal disease in Down's syndrome (DS) individuals develops earlier and is more rapid and extensive than in age-matched normal individuals. The present study evaluated a group of DS patients, who had been participating in a 10-year preventive dental programme, for the impact of the programme on their periodontal status. Methods Thirty DS patients (mean age 23.3 ± 4 years) were compared with 28 age-matched healthy controls (mean age 22.8 ± 5 years). The hygiene level, gingival condition and periodontal status (periodontal probing depth, clinical attachment level and radiographic alveolar bone loss) were determined. Results In spite of similar oral hygiene and gingival measures, DS patients, as opposed to the control ones, had a severe periodontal disease. The prevalence, extent and severity of periodontitis in the DS group were significantly greater than in the control group. The teeth most commonly and severely affected were the lower central incisors and the upper first molars. DS patients lost significantly more teeth due to periodontitis. Conclusions The clinical and radiographic picture found in the present DS group is characteristic of localized aggressive periodontitis. Within the limitations of this study, it seems that the preventive dental programme had no effect on periodontal destruction progression of localized aggressive periodontitis in DS individuals and that impaired oral hygiene plays a relatively minor role in the pathogenesis of this disease. Future controlled studies are needed to assess the effectiveness of different preventive dental programmes in preventing the progression of periodontitis in DS patients. [source] Type 2 diabetes and periodontal indicators: epidemiology in France 2002,2003JOURNAL OF PERIODONTAL RESEARCH, Issue 4 2006C. Mattout Background and Objective:, ,Diabetes and periodontal disease have been associated in the literature. In the present study, the periodontal heath of noninsulin-dependent diabetic adults was compared with that of a general population of nondiabetic patients. Material and Methods:, In France, 2144 adults (age: 35,65 years) were examined for life habits (tobacco, alcohol), biological diagnosis (type II diabetes, arterial hypertension), biometry (weight, size) and biochemistry. Dental and periodontal data included plaque index, gingival index, probing depth, and clinical attachment loss. Results:, Descriptive and multifactorial analysis evidenced a more severe periodontal disease in diabetic patients. Moreover, when the plaque index was held constant, the gingival index was more elevated in diabetics. In nondiabetics, age, gender, glycemia, alcohol, and tobacco smoking were identified as significant risk factors for periodontal disease. In contrast, in diabetic subjects, only tobacco smoking was a significant risk factor. Conclusion:, In type II diabetics, the diabetes factor is probably more significant than periodontal risk factors, age, and gender. [source] Periodontitis and Gestational Diabetes Mellitus: Exploring the Link in NHANES IIIJOURNAL OF PUBLIC HEALTH DENTISTRY, Issue 3 2006Karen F. Novak DDS Abstract Objectives: The authors hypothesized that women with a history of gestational diabetes mellitus (GDM) during pregnancy would exhibit more severe periodontal disease than controls without a history of diabetes during pregnancy. Methods: Data from NHANES III provided information for 4,244 women ages 20,59. One hundred and thirteen had a history of GDM (GDM+), while 4,131 had no history of diabetes before or during their pregnancies (GDM-). Women were further classified by the presence or absence of diabetes mellitus (DM+ or OM-) at the time of their NHANES 111 examination. Periodontal disease (PO) was defined as one or more teeth with one or more sites with probing depth ,4mm, loss of affachment ,2mm, and bleeding on probing. Results: The PD prevalence among women who were GDM+DM- was 9.0% and 4.8% for those who were GDM-DM-. PD prevalence for women who were GDM+DM+ was 30.5% and 11.6% for GDM-DM+ subjects, respectively. A logistic regression model, controlling for age, calculus, smoking, and income estimated women who were GDM+DM+ were more likely to have periodontal disease than women who were GDM-DM- and women who were GDM-DM+. The GDM+DM- group also tended to be more likely to have PD than the GDM-DM- and GDM-DM+ groups. However, the odds ratios were not statistically significant. Conclusions: These results support the hypothesis that women with gestational diabetes mellitus (GDM) during pregnancy may be at greater risk for developing more severe periodontal disease than pregnant women without GDM. [source] The oral health status of patients on oral bisphosphonates for osteoporosisAUSTRALIAN DENTAL JOURNAL, Issue 4 2008R Kunchur Abstract Background:, The oral health status of patients on bisphosphonates is the key to the patient's ongoing health and well-being. If they are orally healthy, invasive bone procedures, particularly extractions can be avoided, then the risk of osteonecrosis of the jaws (ONJ) is low. Methods:, The records of 49 consecutive patients on oral bisphosphonates, referred to the Oral and Maxillofacial Surgery Unit (OMSU) for an oral health check and probable extractions, were retrospectively reviewed. The DMFT, periodontal and pathologic state were calculated from the OPG radiographs. An age and gender matched control group, from patients referred to the OMSU but who were not on oral bisphosphonates, were similarly assessed. Community data were also obtained. Results:, The DMFT score for the oral bisphosphonate group was 29: Decayed 3, Missing 10, Filled 16. The control group DMFT score was 24: Decayed 5, Missing 11, Filled 8. Both groups had advanced periodontal disease (over 95 per cent) and were medically compromised (over 90 per cent). The DMFT for general community data for age matched government pensioners was 19.1: Decayed 0.8, Missing 10.4, Filled 7.9. With severe periodontal disease 23 per cent. Thus, the oral health of the oral bisphosphonate group was similar to the control group and both had more decayed teeth and periodontal disease than community values. Conclusions:, This study confirms that one cannot assume that a patient on an oral bisphosphonate for osteoporosis has a healthy mouth. It supports the view that all patients on bisphosphonates need to be seen by a dentist either before or soon after commencement of bisphosphonate therapy. [source] | ||||||||||