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Serum Zinc (serum + zinc)

Distribution by Scientific Domains

Medical Sciences	60%

Terms modified by Serum Zinc

serum zinc level

Selected Abstracts

Serum Zinc, Chromium, and Iron Concentrations in Dogs with Lymphoma and Osteosarcoma

JOURNAL OF VETERINARY INTERNAL MEDICINE, Issue 6 2001
Kathy J. Kazmierski
We compared serum concentrations of zinc, chromium, and iron in dogs with cancer to those of normal dogs. Dogs with lymphoma (n = 50) and osteosarcoma (n = 52) were evaluated. Dogs with lymphoma had significantly lower (P= .0028) mean serum zinc concentrations (mean ± SD; 1.0 ± 0.3 mg/L) when compared to normal dogs (1.2 ± 0.4 mg/L). Dogs with osteosarcoma also had lower mean serum zinc concentrations (1.1 ± 0.4 mg/L), but this difference was not significant (P= .075). Serum chromium concentrations were significantly lower in dogs with lymphoma (2.6 ± 2.6 ,g/L, P= .0007) and osteosarcoma (2.4 ± 3.1 ,g/L, P= .0001) compared to normal dogs (4.7 ± 2.8 ,g/L). Serum iron concentrations and total iron-binding capacity were significantly lower in dogs with lymphoma (110.8 ± 56.7 ,g/dL, P < .0001, and 236.6 ± 45.6 ,g/dL, P < .0001, respectively) and osteosarcoma (99.6 ± 49.3 ,g/dL, P < .0001, and 245.0 ± 43.8 ,g/dL, P= .0011, respectively) when compared to normal dogs (175.1 ± 56.7 ,g/dL and 277.1 ± 47.4 ,g/dL). Mean ferritin concentration was significantly higher in dogs with lymphoma (1291.7 ± 63.0 ,g/L) than in normal dogs (805.8 ± 291.1 ,g/L, P < .0001) and dogs with osteosarcoma (826.5 ± 309.2 ,g/L, P < .0001). Further investigation is needed to explore the clinical significance of these mineral abnormalities in dogs with cancer. [source]

Serum zinc in small children with coeliac disease

ACTA PAEDIATRICA, Issue 2 2009
Lotta Högberg
Abstract In coeliac disease (CD) there is a gluten-induced small bowel enteropathy leading to malabsorption of various nutrients, vitamins and trace elements. Low levels of serum zinc have been reported in adults with untreated CD. In the present study we related the serum concentration of zinc to the morphology of the small bowel mucosa in 58 children, all under 4 years of age and under investigation for coeliac disease. The mean serum concentration of zinc (mean ± SD; ,mol/L) was significantly lower in children with untreated CD (9.7 ± 2.0) (n = 11) compared to non-coeliac children without enteropathy (15.1 ± 2.3) (n = 16) (p < 0.001), coeliac children on a gluten-free diet without enteropathy (14.2 ± 1.6) (n = 14) (p < 0.001), coeliac children on gluten challenge with enteropathy (14.1 ± 2.1) (n = 12) (p < 0.001) and coeliac children on gluten challenge without enteropathy (13.8 ± 1.9) (n = 6) (p < 0.005). Conclusion: Serum zinc concentration is decreased in untreated coeliac children with enteropathy and normalizes on gluten-free diet. A low serum zinc value in a child being investigated for possible CD on clinical grounds can thus be used as a complementary marker for enteropathy indicating further investigation with small bowel biopsy. The hypothetical role of zinc in the pathogenesis of CD is discussed. [source]

Effects of oyster extract on the reproductive function of zinc-deficient mice: Bioavailability of zinc contained in oyster extract

CONGENITAL ANOMALIES, Issue 4 2003
Yoshikazu Matsuda
ABSTRACT Zinc is a vital nutrient in the normal reproductive function and embryonic development of mammals, and it is well known that oyster extract contains significant amounts of zinc. The effects of oyster extract on reproductive function, such as embryonic development, serum levels of zinc and sperm maturation were examined in zinc-deficient mice. Zinc deficiency in dams during pregnancy induced a decrease in the successful pregnancy rate, maternal weight gain, the number of live fetuses and fetal body weight. Zinc deficiency for 12 weeks in male mice induced a decrease in body weight, testis weight and sperm count in the epididymis. However, reproductive failure, embryonic defects and decreased sperm motility in zinc-deficient mice were improved by supplementation with oyster extract. Some nutrients contained in oyster extract, such as taurine and glycogen, may be related to the recovery of reproductive function. There were significantly lower serum concentrations of zinc in dams fed a zinc-deficient diet However, the serum zinc concentration was normal in the oyster extract-supplemented group. No difference in the concentration of serum zinc was observed between the oyster extract- and zinc carbonate-supplemented groups. From these findings, it is suggested that oyster extract is a useful supplement that can prevent reproductive defects from zinc deficiency, and the bioavailability of zinc may be identical to zinc carbonate. [source]

Effects of dietary zinc levels on growth, serum zinc, haematological parameters and tissue trace elements of soft-shelled turtles, Pelodiscus sinensis

AQUACULTURE NUTRITION, Issue 3 2010
S.-C. HUANG
Abstract A 10-week feeding trial was conducted to evaluate the effects of dietary zinc (Zn) contents on the growth, tissue trace element contents and serum Zn levels in soft-shelled turtles, Pelodiscus sinensis. Juvenile soft-shelled turtles approximately 4.8 g in body weight were fed casein-based diets containing seven levels of Zn (14, 23, 32, 43, 58, 87 and 100 mg kg,1) for 10 weeks. There were no significant differences (P > 0.05) in weight gain (WG), feed conversion ratio (FCR) or protein efficiency ratio (PER) among the dietary treatments. However, Zn concentrations in the liver, serum and carapace of turtles fed the basal diet containing 14 mg Zn kg,1 were the lowest among all groups. Zn contents in the liver, serum and carapace increased when dietary Zn increased up to a dietary Zn level of approximately 43 mg kg,1. Beyond this dietary level, tissue Zn contents were relatively constant. Carapace iron (Fe), selenium (Se) in hard tissues and haemoglobin concentrations decreased when dietary Zn increased. Dietary Zn requirements of juvenile soft-shelled turtles derived from regression modelling using the liver, serum, carapace and bone Zn contents as indicators were 42, 39, 35 and 46 mg Zn kg,1, respectively. [source]