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Secondary Importance (secondary + importance)
Selected AbstractsThe relative importance of landscape and community features in the invasion of an exotic shrub in a fragmented landscapeECOGRAPHY, Issue 2 2006Anne M. Bartuszevige Although invasive plants are recognized as a major ecological problem, little is known of the relative importance of plant community characteristics versus landscape context in determining invasibility of communities. We determined the relative importance of community and landscape features of 30 woodlots in influencing the invasion of Lonicera maackii. We sampled woodlots using the point-quarter method and calculated canopy openness and basal areas and densities of shrub, sapling and tree species, as well as woody species richness. We used aerial photos and ArcView GIS to calculate landscape parameters from the same woodlots using a buffer distance of 1500,m. We used logistic and linear regression analyses to determine the community and landscape factors that best explain L. maackii presence and density. We also tested whether woodlot invasion by L. maackii begins at woodlot edges. Presence of L. maackii was significantly explained only by distance from the nearest town (logistic regression, p=0.017); woodlots nearer town were more likely to be invaded. Among invaded woodlots, density of L. maackii was positively related to the amount of edge in the landscape (partial R2=0.592) and negatively related to total tree basal area (partial R2=0.134), number of native woody species (partial R2=0.054), and sapling shade tolerance index (partial R2=0.054). Lonicera maackii in woodlot interiors were not younger than those on the perimeters, leading us to reject the edge-first colonization model of invasion. Our findings reveal that landscape structure is of primary importance and community features of secondary importance in the invasion of L. maackii. This shrub is invading from multiple foci (towns) rather than an advancing front. Connectivity in the landscape (i.e. the number of corridors) did not promote invasion. However, edge habitat was important for invasion, probably due to increased propagule pressure. The community features associated with L. maackii invasion may be indicators of past disturbance. [source] Partisan responses to Europe: Comparing Finnish and Swedish political partiesEUROPEAN JOURNAL OF POLITICAL RESEARCH, Issue 2 2001KARL MAGNUS JOHANSSON This article analyzes party responses to European integration in Finland andSweden. We argue that such responses are shaped by seven explanatory factors: basic ideology, public opinion, factionalism, leadership influence, party competition, transnational links, and the development of integration. Each factor can lead to a positive or a negative evaluation of the European Union. In the empirical analysis, the sample includes all parties represented in the respective national parliaments, and the research material consists of party documents, parliamentary votes, statements by leading party figures, public opinion surveys, direct observation and interviews. Party competition and leadership influence are the strongest factors in the Finnish case, while public opinion and factionalism are the strongest factors in Sweden. Issue avoidance combined with the secondary importance of the EU in party politics explain why parties have been relatively successful in containing internal factionalism and discord, especially in Finland. [source] Clonal diversity and subpopulation structure in central European relict populations of Saxifraga paniculataMill. (Saxifragaceae)FEDDES REPERTORIUM, Issue 3-4 2004C. Reisch Saxifraga paniculata is a rare and endangered glacial relict in central Europe. It shows high clonal reproduction. In this study, we analysed the clonal diversity and the subpopulation structure of three populations from the species main distribution area in Germany outside of the Alps (Swabian Alb, Black Forest, Nahe Mountains). We used RAPD analysis to detect the genetic variation in S. paniculata and found high levels of clonal diversity. The percentage of distinguishable genotypes (PD) within populations of S. paniculata was 1.0 and even spatially well defined mats of rosettes consisted of several genotypes. In a cluster analysis, the investigated populations were clearly separated from each other. However, we detected no genetic differentiation among subpopulations. We ascribe the high level of genotypic variability to the species' mixed mating system, which creates and maintains high levels of genetic diversity within the populations of S. paniculata. Clonal reproduction seems, meanwhile, to be of secondary importance for the propagation of the species. (© 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) Klonale Diversität und Subpopulationsstruktur in mitteleuropäischen Reliktpopulationen von Saxifraga paniculataMill. (Saxifragaceae) Saxifraga paniculata ist in Mitteleuropa ein seltenes und gefährdetes Glazialrelikt, das sich durch die Fähigkeit zu starker klonaler Reproduktion auszeichnet. Die vorliegende Arbeit befasst sich mit der klonalen Diversität und der Subpopulationsstruktur von drei Populationen aus dem Hauptverbreitungsgebiet der Art außerhalb der Alpen (Schwäbische Alb, Schwarzwald, Nahe-Bergland). Die genetische Variabilität wurde mittels RAPD-Analyse untersucht. Dabei konnte ein hohes Maß an klonaler Diversität festgestellt werden. Der Prozentsatz unterscheidbarer Genotypen innerhalb einer Population (PD) betrug 1.0 und selbst größere Matten, deren Entstehung nach rein morphologischer Einschätzung auf klonalem Wachstum beruhen müsste, bestanden aus mehreren Genotypen. In einer Clusteranalyse unterschieden sich die analysierten Populationen klar voneinander. Unterschiede zwischen Subpopulationen konnten jedoch nicht nachgewiesen werden. Das hohe Ausmaß an genetischer Diversität kann dem "mixed mating system" der Art zugeschrieben werden, das genetische Variabilität schafft und erhält. Klonales Wachstum scheint währenddessen eher von zweitrangiger Bedeutung für die Vermehrung der Art zu sein. [source] Some Hypotheses on the Nature of Difficulty and Ease in Second Language Reading: An Application of Schema TheoryFOREIGN LANGUAGE ANNALS, Issue 6 2000Philip C. Hauptman A traditional view of difficulty/ease is explained as consisting of two factors: (1) Language (grammar and vocabulary) and (2) Text Length. A modern view of difficulty/ease is then proposed via four hypotheses: (1) The first Primary Ease Factor in L2 reading is background knowledge; (2) Signalling becomes the Primary Ease Factor in L2 reading when background knowledge is not useful for accessing content schemata; (3) Other factors being equal, the degree of signalling determines the degree of accessibility of a text for the L2 reader; and (4) Other factors being equal, Language, Discourse, and Length are of secondary importance , after Background Knowledge and Signalling , for accessing a text by L2 readers. [source] Mass balance of a slope glacier on Kilimanjaro and its sensitivity to climateINTERNATIONAL JOURNAL OF CLIMATOLOGY, Issue 7 2008Thomas Mölg Abstract Meteorological and glaciological measurements obtained at 5873 m a.s.l. on Kersten Glacier, a slope glacier on the southern flanks of Kilimanjaro, are used to run a physically-based mass balance model for the period February 2005 to January 2006. This shows that net shortwave radiation is the most variable energy flux at the glacier-atmosphere interface, governed by surface albedo. The majority of the mass loss (,65%) is due to sublimation (direct conversion of snow/ice to water vapour), with melting of secondary importance. Sensitivity experiments reveal that glacier mass balance is 2,4 times more sensitive to a 20% precipitation change than to a 1 °C air temperature change. These figures also hold when the model is run with input data representative of a longer term (1979,2004) mean period. Results suggest that a regional-scale moisture projection for the 21st century is crucial to a physically-based prediction of glacier retention on Africa's highest mountain. Copyright © 2007 Royal Meteorological Society [source] Factors affecting the uptake of new medicines in secondary care , a literature reviewJOURNAL OF CLINICAL PHARMACY & THERAPEUTICS, Issue 4 2008D. Chauhan BPharm MRPharmS MSc Summary Background and Objective:, The rate of uptake of new medicines in the UK is slower than in many other OECD countries. The majority of new medicines are introduced initially in secondary care and prescribed by specialists. However, the reasons for relatively low precribing levels are poorly understood. This review explores the determinants of uptake of new medicines in secondary care. Methods:, Nine electronic databases were searched covering the period 1992,2006. Once the searches had been run, records were downloaded and those which evaluated uptake of new medicines in secondary care were identified. UK studies were of primary interest, although research conducted in other countries was also reviewed if relevant. With the exception of ,think pieces', eligibility was not limited by study design. Studies published in languages other than English were excluded from the review. Determinants of uptake in secondary care were classified using Bonair and Persson's typology for determinants of the diffusion of innovation. Results:, Almost 1400 records were screened for eligibility, and 29 studies were included in the review. Prescribing of new medicines in secondary care was found to be subject to a number of interacting influences. The support structures which exist within secondary care facilitate access to other colleagues and shape prescribing practices. Clinical trial investigators and physicians who sit on decision-making bodies such as Drug and Therapeutic Committees (DTCs) appear to have a special influence due to their proximity to their research and understanding of evidence base. Pharmaceutical representatives may also influence prescribing decisions through funding of meetings and academic detailing, but clinicians are wary of potential bias. Little evidence on the influence of patients upon prescribing decisions was identified. The impact of clinical guidelines has been variable. Some guidelines have significantly increased the uptake of new medicines, but others have had little discernible impact despite extensive dissemination. However given the increasing influence of the National Institute for Health and Clinical Excellence, guidelines may become more important. The impact of financial prescribing incentives on secondary care prescribing is unclear. Although cost and budget may influence hospital prescribing of new drugs, they are of secondary importance to the safety and effectiveness profile of the medicine. If a drug has a novel mechanism of action, or belongs to a class with few alternatives, clinicians are more likely to consider it favourably as a prescribing option. Conclusions:, Although price does not appear to be a primary factor behind prescribing decision-making, in secondary care there has long been a historical need for formal purchasing decisions through the DTC, which differentiates it from primary care. This, in addition to increasing pressures for cost-effectiveness within the NHS means that cost will appear more frequently on clinician consciousness. As a result, guidelines are more likely to be implemented using the strong professional networks in existence within secondary care, and although the influence of patients has not been addressed by the literature, they are likely to have an increasing input into the prescribing decision, given the importance of patient involvement in current UK policy. [source] A model selection approach for the identification of quantitative trait loci in experimental crossesJOURNAL OF THE ROYAL STATISTICAL SOCIETY: SERIES B (STATISTICAL METHODOLOGY), Issue 4 2002Karl W. Broman Summary. We consider the problem of identifying the genetic loci (called quantitative trait loci (QTLs)) contributing to variation in a quantitative trait, with data on an experimental cross. A large number of different statistical approaches to this problem have been described; most make use of multiple tests of hypotheses, and many consider models allowing only a single QTL. We feel that the problem is best viewed as one of model selection. We discuss the use of model selection ideas to identify QTLs in experimental crosses. We focus on a back-cross experiment, with strictly additive QTLs, and concentrate on identifying QTLs, considering the estimation of their effects and precise locations of secondary importance. We present the results of a simulation study to compare the performances of the more prominent methods. [source] Exploitation of food resources by badgers (Meles meles) in the Swiss Jura MountainsJOURNAL OF ZOOLOGY, Issue 2 2005C. Fischer Abstract In our study three badger Meles meles populations separated by only a few km but subjected to different environmental conditions were compared. Differences are especially marked for climatic factors, the three areas being located at different altitudes, and for intensivity of soil use by people. The diet of the three populations was significantly different, with one or two dominant items in each area: mammals and cereals in the mountain, maize in the mid-mountain and in the lowland areas. In the most intensively cultivated area, maize was the most consumed item in autumn and spring, several months after harvesting. Earthworms had only a secondary importance in the diet in the mountainous area, but were negligible in the mid-mountain and lowland areas. Soil management seemed to play a preponderant role, mostly owing to soil quality and topography. Climate seemed to have a secondary effect only. [source] Observations at terrestrial impact structures: Their utility in constraining crater formationMETEORITICS & PLANETARY SCIENCE, Issue 2 2004Richard A. F. Grieve Local geology of the target area tends to be of secondary importance, and the net result is that impacts of similar size on a given planetary body produce similar results. This is the essence of the utility of observations at impact craters, particularly terrestrial craters, in constraining impact processes. Unfortunately, there are few well-documented results from systematic contemporaneous campaigns to characterize specific terrestrial impact structures with the full spectrum of geoscientific tools available at the time. Nevertheless, observations of the terrestrial impact record have contributed substantially to fundamental properties of impact. There is a beginning of convergence and mutual testing of observations at terrestrial impact structures and the results of modeling, in particular from recent hydrocode models. The terrestrial impact record provides few constraints on models of ejecta processes beyond a confirmation of the involvement of the local substrate in ejecta lithologies and shows that Z-models are, at best, first order approximations. Observational evidence to date suggests that the formation of interior rings is an extension of the structural uplift process that occurs at smaller complex impact structures. There are, however, major observational gaps and cases, e.g., Vredefort, where current observations and hydrocode models are apparently inconsistent. It is, perhaps, time that the impact community as a whole considers documenting the existing observational and modeling knowledge gaps that are required to be filled to make the intellectual breakthroughs equivalent to those of the 1970s and 1980s, which were fueled by observations at terrestrial impact structures. Filling these knowledge gaps would likely be centered on the later stages of formation of complex and ring structures and on ejecta. [source] Histologic classification of ductal carcinoma in situMICROSCOPY RESEARCH AND TECHNIQUE, Issue 2 2002Shabnam Jaffer Abstract Prior to the current mammographic era, ductal carcinoma in situ (DCIS) usually presented as a large mass, was classified morphologically by architecture, and treated by mastectomy. The introduction of screening mammography led to an increase in the incidence of DCIS, a decrease in the average size of DCIS, and an increased emphasis on its heterogeneous nature. Thus, a reproducible and prognostically relevant classification system for DCIS is necessary. The ultimate goal of this classification is proper selection of patients for whom lumpectomy would suffice rather than mastectomy. Features to evaluate include: extent and size of disease, adequacy of resection margins, and histology. While none of the proposed histological classification systems were endorsed at the recent Consensus Conference on the Classification of DCIS, nuclear grade was the most important feature common to most of them. Architecture was given secondary importance. By definition, DCIS is a non-invasive clonal proliferation of epithelial cells originating in the terminal duct lobular unit, which would be expected to be monomorphic; however, it is the degree of nuclear pleomorphism that is primarily used to separate DCIS into low, intermediate, and high grades. Architecturally, DCIS has been divided into the following types: comedo, solid, cribriform, micropapillary, and papillary. Different architectural patterns and grades may be present in a given particular case; however, some combinations of patterns occur more frequently than others. Interobserver studies have shown nuclear grading to be interpreted with greater consistency than architecture, and nuclear grading methods have correlated with biological and molecular marker studies. Microsc. Res. Tech. 59:92,101, 2002. © 2002 Wiley-Liss, Inc. [source] Layers of defense responses to Leptosphaeria maculans below the RLM1 - and camalexin-dependent resistancesNEW PHYTOLOGIST, Issue 2 2009Mattias Persson Summary ,,Plants have evolved different defense components to counteract pathogen attacks. The resistance locus resistance to Leptosphaeria maculans 1 (RLM1) is a key factor for Arabidopsis thaliana resistance to L. maculans. The present work aimed to reveal downstream defense responses regulated by RLM1. ,,Quantitative assessment of fungal colonization in the host was carried out using quantitative polymerase chain reaction (qPCR) and GUS expression analyses, to further characterize RLM1 resistance and the role of salicylic acid (SA), jasmonic acid (JA), and ethylene (ET) in disease development. Additional assessments of A. thaliana mutants were performed to expand our understanding of this pathosystem. ,,Resistance responses such as lignification and the formation of vascular plugs were found to occur in an RLM1 -dependent manner, in contrast to the RLM1 -independent increase in reactive oxygen species at the stomata and hydathodes. Analyses of mutants defective in hormone signaling in the camalexin-free rlm1Lerpad3 background revealed a significant influence of JA and ET on symptom development and pathogen colonization. ,,The overall results indicate that the defense responses of primary importance induced by RLM1 are all associated with physical barriers, and that responses of secondary importance involve complex cross-talk among SA, JA and ET. Our observations further suggest that ET positively affects fungal colonization. [source] An Examination of Labor Productivity Growth and Structural Changes in the Singapore Labor Force,ASIAN ECONOMIC JOURNAL, Issue 3 2002Chong-Yah Lim This paper ,rst examines the sources of growth in the Singapore economy by decomposing real per capita gross domestic product (GDP) growth into two components. It is found that, for the period 1974,1999, labor productivity was a signi,cant source of economic growth in Singapore. Conversely, the contribution of the rate of change in employment ratio was only of secondary importance. On further decomposition, the rate of change in employment ratio was due mainly to rate of change in population age-structure ratio and rate of change in labor-force participation rate. Growth patterns of the labor force were examined after it has been segregated according to gender, citizenship and age group independently. Labor productivity growth was highest in the transport, storage and communication sector, while labor productivity growth was lowest in the ,nancial, insurance, real estate and business services sector. [source] Sensitivity Analyses for Ecological RegressionBIOMETRICS, Issue 1 2003Jon Wakefield Summary. In many ecological regression studies investigating associations between environmental exposures and health outcomes, the observed relative risks are in the range 1.0,2.0. The interpretation of such small relative risks is difficult due to a variety of biases,some of which are unique to ecological data, since they arise from within-area variability in exposures/confounders. The potential for residual spatial dependence, due to unmeasured confounders and/or data anomalies with spatial structure, must also be considered, though it often will be of secondary importance when compared to the likely effects of unmeasured confounding and within-area variability in exposures/confounders. Methods for addressing sensitivity to these issues are described, along with an approach for assessing the implications of spatial dependence. An ecological study of the association between myocardial infarction and magnesium is critically reevaluated to determine potential sources of bias. It is argued that the sophistication of the statistical analysis should not outweigh the quality of the data, and that finessing models for spatial dependence will often not be merited in the context of ecological regression. [source] Towards a Methodology for Developing Evidence-Informed Management Knowledge by Means of Systematic ReviewBRITISH JOURNAL OF MANAGEMENT, Issue 3 2003David Tranfield Undertaking a review of the literature is an important part of any research project. The researcher both maps and assesses the relevant intellectual territory in order to specify a research question which will further develop the knowledge base. However, traditional ,narrative' reviews frequently lack thoroughness, and in many cases are not undertaken as genuine pieces of investigatory science. Consequently they can lack a means for making sense of what the collection of studies is saying. These reviews can be biased by the researcher and often lack rigour. Furthermore, the use of reviews of the available evidence to provide insights and guidance for intervention into operational needs of practitioners and policymakers has largely been of secondary importance. For practitioners, making sense of a mass of often-contradictory evidence has become progressively harder. The quality of evidence underpinning decision-making and action has been questioned, for inadequate or incomplete evidence seriously impedes policy formulation and implementation. In exploring ways in which evidence-informed management reviews might be achieved, the authors evaluate the process of systematic review used in the medical sciences. Over the last fifteen years, medical science has attempted to improve the review process by synthesizing research in a systematic, transparent, and reproducible manner with the twin aims of enhancing the knowledge base and informing policymaking and practice. This paper evaluates the extent to which the process of systematic review can be applied to the management field in order to produce a reliable knowledge stock and enhanced practice by developing context-sensitive research. The paper highlights the challenges in developing an appropriate methodology. [source] | ||||||||||||||||||||||