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Secondary Alcohols (secondary + alcohol)

Distribution by Scientific Domains
Chemistry95%
Life Sciences2%
Distribution within Chemistry
Organic Chemistry71%
General & Introductory Chemistry10%
6 Other Subdomains19%

Kinds of Secondary Alcohols

  • active secondary alcohol
    		•
  • chiral secondary alcohol
    		•

    Selected Abstracts

    Kinetic Resolution of Racemic Secondary Alcohols Mediated by N -Methylimidazole in the Presence of Optically Active Acyl Chlorides

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 14 2010
    Loïc Leclercq
    Abstract N -Methylimidazole was used to promote the acylation of secondary racemic alcohols and to carry out their kinetic resolution through intermediate chiral acyl imidazolium chlorides. The kinetic resolution could be turned into a catalytic process in the presence of a catalytic amount of N -methylimidazole. [source]

    One-Pot Synthesis of Carbamoyl Azides Directly from Primary Alcohols and Oxidation of Secondary Alcohols to Ketones Using Iodobenzene Dichloride in Combination with Sodium Azide

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 14-15 2009
    Xiao-Qiang Li
    Abstract An effective synthesis of carbamoyl azides directly from primary alcohols using iodobenzene dichloride in combination with sodium azide has been developed. Moreover, the same regent combination was also efficient for the oxidation of secondary alcohols to the corresponding ketones. [source]

    An Efficient Approach to Chiral Ferrocene-Based Secondary Alcohols via Asymmetric Hydrogenation of Ferrocenyl Ketones

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 3 2006
    Wing-Sze Lam
    Abstract P-Phos-ruthenium-DPEN precatalysts have been found to be efficient for the asymmetric hydrogenation of various ferrocenyl ketones. The use of (R)-xylyl-P-PhosRuCl2(R,R)-DPEN generated chiral ferrocenylethanol in 99.3% e.e. with >99% conversion in a 150-g scale. [source]

    Polymer-Supported Bisacetoxybromate(I) Anion ,-An Efficient Co-Oxidant in the TEMPO-Mediated Oxidation of Primary and Secondary Alcohols

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 5 2003
    Marco Brünjes
    Abstract A polymer-bound reagent for the efficient oxidation of primary alcohols to aldehydes and secondary alcohols to ketones in the presence of a catalytic amount of 2,2,6,6-tetramethyl-1-piperidinyloxyl (TEMPO) is described. The oxidation process is particular mild and allows one to prepare aldehydes with ,-chirality without racemization. This also includes the synthesis of ,-aminoaldehydes. In most cases, work-up of this heavy metal-free oxidation is achieved by simple filtration followed by removal of the solvent. Insight into the role of the bromate(I) anion in the oxidation process was gained from the TEMPO-mediated oxidation of benzaldehyde in the presence of the hypochlorite anion loaded on an anion exchange resin. [source]

    Full Chirality Transfer in the Conversion of Secondary Alcohols into Tertiary Boronic Esters and Alcohols Using Lithiation,Borylation Reactions,

    ANGEWANDTE CHEMIE, Issue 30 2010
    Viktor Bagutski Dr.
    Der Zusatz zählt: Mit MgBr2/MeOH als Additiv verläuft die Lithiierung-Borylierung mit fast 100,% Retention der Konfiguration und liefert so tertiäre Boronsäureester (oder tertiäre Alkohole) mit außergewöhnlich hohen ee -Werten , selbst bei erheblich gehinderten Substraten und stärker stabilisierten lithiierten Carbamaten (siehe Schema; Cb=Carbamat, pin=OCMe2CMe2O). [source]

    ChemInform Abstract: Efficient Aerobic Ruthenium-Catalyzed Oxidation of Secondary Alcohols by the Use of a Hybrid Electron Transfer Catalyst.

    CHEMINFORM, Issue 33 2010
    Eric V. Johnston
    Abstract An efficient biomimetic catalyst system for the title reaction is developed. [source]

    ChemInform Abstract: Homogeneous, Anaerobic (N-Heterocyclic Carbene),Pd or ,Ni Catalyzed Oxidation of Secondary Alcohols at Mild Temperatures.

    CHEMINFORM, Issue 4 2010
    Christophe Berini
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Preparation of Novel Axially Chiral NHC,Pd(II) Complexes and Their Application in Oxidative Kinetic Resolution of Secondary Alcohols.

    CHEMINFORM, Issue 35 2009
    Shi-Jia Liu
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Palladium-Catalyzed Enantioselective Oxidation of Chiral Secondary Alcohols: Access to Both Enantiomeric Series.

    CHEMINFORM, Issue 50 2008
    David C. Ebner
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: A Chiral Mn(III) Salen Complex Immobilized onto Ionic Liquid Modified Mesoporous Silica for Oxidative Kinetic Resolution of Secondary Alcohols.

    CHEMINFORM, Issue 47 2008
    Suman Sahoo
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Etherification of (E)-1,3-Diaryl- and (E)-1,3-Diheteroaryl-prop-2-en-1-ols with Primary and Secondary Alcohols over Platinum on Carbon.

    CHEMINFORM, Issue 8 2008
    Thies Thiemann
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Efficient Conversion of Primary and Secondary Alcohols to Primary Amines.

    CHEMINFORM, Issue 7 2008
    Weilin Sun
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    (S)-Selective Kinetic Resolution and Chemoenzymatic Dynamic Kinetic Resolution of Secondary Alcohols.

    CHEMINFORM, Issue 16 2006
    Linnea Boren
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

    The Stereoselective Synthesis of ,-Substituted ,-Amino Secondary Alcohols Based on the Proline-Mediated, Asymmetric, Three-Component Mannich Reaction and Its Application to the Formal Total Synthesis of Nikkomycins B and Bx.

    CHEMINFORM, Issue 12 2006
    Yujiro Hayashi
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

    Direct ,-Alkylation of Secondary Alcohols with Primary Alcohols Catalyzed by a Cp*Ir Complex.

    CHEMINFORM, Issue 1 2006
    Ken-ichi Fujita
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]

    Removal of the Acyl Donor Residue Allows the Use of Simple Alkyl Esters as Acyl Donors for the Dynamic Kinetic Resolution of Secondary Alcohols.

    CHEMINFORM, Issue 38 2005
    Gerard K. M. Verzijl
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]

    Oxidation of Secondary Alcohols with Phenyltrimethylammonium Tribromide in the Presence of a Catalytic Amount of Antimony(III) Bromide or Copper(II) Bromide.

    CHEMINFORM, Issue 18 2005
    Shinsei Sayama
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]

    A Heterobimetallic Rhodium(I),Ruthenium(II) Catalyst for the Oppenauer-Type Oxidation of Primary and Secondary Alcohols under Mild Conditions.

    CHEMINFORM, Issue 47 2004
    Sebastien Gauthier
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]

    Asymmetric Synthesis of Secondary Alcohols from Primary Alcohols via Intramolecular Carbenoid C,H Insertion Catalyzed by Rhodium(II) 3-Phenylcholestane-2-carboxylate.

    CHEMINFORM, Issue 33 2004
    Cheol Hee Hwang
    No abstract is available for this article. [source]

    The Application of N,N,-Dibromo-N,N,-1,2-ethanediylbis(p-toluenesulfonamide) as a Powerful Reagent for the Oxidation of Primary and Secondary Alcohols to Aldehydes and Ketones.

    CHEMINFORM, Issue 52 2003
    Ramin Ghorbani-Vaghei
    No abstract is available for this article. [source]

    Sulfenamide-Catalyzed Oxidation of Primary and Secondary Alcohols with Molecular Bromine.

    CHEMINFORM, Issue 25 2003
    Jun-ichi Matsuo
    No abstract is available for this article. [source]

    Efficient and Highly Selective Oxidation of Primary and Secondary Alcohols by Butyltriphenylphosphonium Chlorochromate under Non-Aqueous Conditions.

    CHEMINFORM, Issue 16 2003
    Abdol R. Hajipour
    No abstract is available for this article. [source]

    ChemInform Abstract: The Mn(acac)3 -RCN-CCl4 System as a New Efficient Reagent for the Oxidation of Secondary Alcohols into Ketones.

    CHEMINFORM, Issue 49 2002
    R. I. Khusnutdinov
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: A Sequential Application of Kinetic Resolution and Polymer-Supported Scavenging for the Isolation of Chiral Secondary Alcohols.

    CHEMINFORM, Issue 48 2001
    Armando Cordova
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Nonenzymatic Kinetic Resolution of Secondary Alcohols: Enantioselective SN2 Displacement of Hydroxy Groups by Halogens in the Presence of Chiral BINAP.

    CHEMINFORM, Issue 30 2001
    Govindasamy Sekar
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: NaBrO3,FeCl3 as a New Reagent for Oxidation of Benzylic and Secondary Alcohols to Carbonyl Compounds.

    CHEMINFORM, Issue 24 2001
    Ahmad Shaabani
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    An Improved Ruthenium Catalyst for the Environmentally Benign Amination of Primary and Secondary Alcohols

    CHEMISTRY - AN ASIAN JOURNAL, Issue 3 2007
    Dirk Hollmann
    Abstract The N-alkylation of amines in the presence of different ruthenium catalysts generated in,situ was investigated. Among the various catalysts tested, the combination of [Ru3(CO)12] and N -phenyl-2-(dicyclohexylphosphanyl)pyrrole showed the best performance. By applying this novel catalyst, a variety of functionalized alcohols and amines were converted into the corresponding secondary amines in high yield. Die Synthese von sekundären Aminen aus primären Aminen und Alkoholen ist eine salzfreie und damit umweltfreundliche Alternative zu den bisherigen Alkylierungsverfahren. Durch die in,situ Dehydrierung,Kondensation,Hydrierung Reaktionsequenz, welche die Vorteile der Transferhydrierung nutzt, wurden die Produkte atomeffizient hergestellt. Ermöglicht wird dies durch die einen neuartigen Ruthenium Katalysator bestehend aus [Ru3(CO)12] und N -phenyl-2-(dicyclohexylphosphanyl)pyrrol. Der robuste und wasserstabile Katalysator ermöglicht die Synthese von funktionalisierten Aminen in guten bis sehr guten Ausbeuten. [source]

    TEMPO and Carboxylic Acid Functionalized Imidazolium Salts/Sodium Nitrite: An Efficient, Reusable, Transition Metal-Free Catalytic System for Aerobic Oxidation of Alcohols

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 13 2009
    Cheng-Xia Miao
    Abstract An effective catalytic system comprising a 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) functionalized imidazolium salt ([Imim-TEMPO]+,X,), a carboxylic acid substituted imidazolium salt ([Imim-COOH]+,X,), and sodium nitrite (NaNO2) was developed for the aerobic oxidation of aliphatic, allylic, heterocyclic and benzylic alcohols to the respective carbonyl compounds with excellent selectivity up to >99%, even at ambient conditions. Notably, the catalyst system could preferentially oxidize a primary alcohol to the aldehyde rather than a secondary alcohol to the ketone. Moreover, the reaction rate is greatly enhanced when a proper amount of water is present. And a high turnover number (TON 5000) is achieved in the present transition metal-free aerobic catalytic system. Additionally, the functionalized imidazolium salts are successfully reused at least four times. This process thus represents a greener pathway for the aerobic oxidation of alcohols into carbonyl compounds by using the present task-specific ionic liquids in place of the toxic and volatile additive, such as hydrogen bromide, bromine, or hydrogen chloride (HBr, Br2 or HCl), which is commonly required for the transition metal-free aerobic oxidation of alcohols. [source]

    Hydrosilylation of Ketone and Imine over Poly-N-Heterocyclic Carbene Particles

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2009
    MeiXuan Tan
    Abstract N-Heterocyclic carbene (NHC)-catalyzed ketone/imine hydrosilylation, silane alcohol condensation and asymmetric ketone hydrosilylation reactions were demonstrated for the first time over solid, main-chain poly-NHC particles. The stable and robust poly-NHC particles were easily recovered, and exhibited good catalytic recyclability. A novel chiral induction protocol with a cheap and easily accessible secondary alcohol as the chiral source was also developed in this catalytic system. [source]

    Chemoenzymatic Route to Both Enantiomers of a 1-Isopropyl-3a-methyloctahydroinden-4-one Derivative: A Synthetic Intermediate for Sesqui- and Diterpenoids

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 7-8 2005
    Shigeo Fujieda
    Abstract On the way to a chemoenzymatic synthesis of a key intermediate for sesquiterpenoids and diterpenoids, 2-methyl-2-(4-methyl-3-oxopentyl)-1,3-cyclohexanedione was reduced with the whole cells of yeast biocatalysts. Torulaspora delbrueckii NBRC10921 reduced a cyclic ketone of three carbonyl groups in an enantiofacially selective manner (re -face attack), but there was poor enantiotopic group selectivity between two carbonyl groups on the cyclohexane ring to yield a mixture of diastereomeric products. Candida floricola IAM13115 reduced mainly the pro -(R) carbonyl group. In contrast, the reduction proceeded in an enantiofacially poorly selective manner to give another set of diastereomeric products. In both cases, another carbonyl group on the side chain worked as a ,trapping arm' of the resulting secondary alcohol. The diastereomeric products were effectively separated as the ,syn' or ,cis' isomer exclusively exist in the intramolecular hemiacetal structure, while ,anti' or ,trans' isomer being an equilibrated mixture of cyclic hemiacetal and open-chain hydroxyketone (ca. 0.7,:,1). Starting separately from the enantiomerically enriched products as above, both enantiomers of the target compound, a key intermediate for terpenoids, were efficiently prepared via stereoselective ring closure under pinacol coupling reaction conditions. Furthermore, a daucane sesquiterpene intermediate, a hydroazulene derivative, was provided after one-carbon homologation of the six-membered ring. [source]