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Selected AbstractsPhotoepilation Results of Axillary Hair in Dark-Skinned Patients by IPL: A Comparison Between Different Wavelength and Pulse WidthDERMATOLOGIC SURGERY, Issue 2 2006JONG HEE LEE MD BACKGROUND Recently, intense pulsed light (IPL) sources have been shown to provide long-term hair removal. OBJECTIVE This study examined the photoepilatory effects of different wavelengths and pulse width application in the same device and compared their efficiencies in Asian skin. METHODS Twenty-eight Korean women were treated using HR (600,950 nm filter) and 27 using HR-D (645,950 nm filter) in the axillar area. Four treatments were carried out at intervals of 4 to 6 weeks; follow-ups were conducted 8 months after the last treatment. Mean energy settings were 14.9±2.0 J/cm2 for HR and 17.1±0.6 J/cm2 for HR-D. Longer pulse widths were applied in case of HR-D treatment. Hair counts and photographic evaluation of skin sites were made at baseline and at the last follow-up. Final overall evaluations were performed by patients and clinicians. RESULTS Average clearances of 52.8% and 83.4% were achieved by HR and HR-D, respectively. No significant adverse effects were reported after HR-D treatment. One case each of hypopigmentation and hyperpigmentation was reported for HR. CONCLUSION An IPL source by removing 45 nm of the emitted spectra and applying longer pulse width was found to provide a safer and more effective means of photoepilation in Asian patients. [source] Microfluidic devices for electrokinetic sample fractionationELECTROPHORESIS, Issue 15 2010Zhen Wang Abstract We present three generations of microchip-based "in-space" sample fractionators and collectors for use in proteomics. The basic chip design consisted of a single channel for CE separation of analytes that then intersects a fractionation zone feed into multiple high aspect ratio microchannels for fractionation of separated components. Achievements of each generation are discussed in relation to important design criteria. CE-separated samples were electrokinetically driven to multiple collection channels in sequence without cross-contamination under the protection of sheath streams. A 36-channel fractionator demonstrated the efficacy of a high-throughput fractionator with no observed cross-contamination. A mixture of IgG and BSA was used to test the efficiency of the fractionator and collector. CE of the fractionated samples was performed on the same device to verify their purity. Our demonstration proved to be efficient and reproducible in obtaining non-contaminated samples over 15 sample injections. Experimental results were found to be in close agreement with PSpice simulation in terms of flow behavior, contamination control and device performance. The design presented here has a great potential to be integrated in proteomic platforms. [source] Monitoring the Channel Formation in Organic Field-Effect Transistors via Photoinduced Charge TransferADVANCED FUNCTIONAL MATERIALS, Issue 5 2009Thokchom Birendra Singh Abstract Conducting channel formation in organic field-effect transistors (OFETs) is considered to happen in the organic semiconductor layer very close to the interface with the gate dielectric. In the gradual channel approximation, the local density of accumulated charge carriers varies as a result of applied gate bias, with the majority of the charge carriers being localized in the first few semiconductor monolayers close to the dielectric interface. In this report, a new concept is employed which enables the accumulation of charge carriers in the channel by photoinduced charge transfer. An OFET employing C60 as a semiconductor and divinyltetramethyldisiloxane-bis(benzocyclobutene) as the gate dielectric is modified by a very thin noncontinuous layer of zinc-phthalocyanine (ZnPc) at the semiconductor/dielectric interface. With this device geometry, it is possible to excite the phthalocyanine selectively and photogenerate charges directly at the semiconductor/dielectric interface via photoinduced electron transfer from ZnPc onto C60. Thus the formation of a gate induced and a photoinduced channel in the same device can be correlated. [source] Safety of Deferring the Reimplantation of Pacing Systems After Their Removal for Infectious Complications in Selected Patients: A 1-Year Follow-Up StudyJOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, Issue 5 2010ELOI MARIJON M.D. Introduction: Recent expert consensus guidelines mention that one of the principles for infected device replacement following removal is to "reevaluate carefully if there is a continued need for a new cardiac device replacement." This is a Class I recommendation, which nevertheless suffers from a very low level of evidence (level of evidence C), since no study has revisited the systematic practice of reimplanting the same device based on a meticulous clinical reassessment. In the present paper, we examined the safety of withholding the implantation of pacing systems in selected patients. Methods and Results: Between January 2005 and December 2007, 188 consecutive patients underwent extractions of infected pacing systems at 2 medical centers. "Low-risk" patients were identified by (1) a spontaneous heart rate >45 bpm, (2) no symptomatic asystole during monitoring, (3) QRS duration <120 ms when history of AV block was noted, (4) no high-degree AV block during continuous monitoring. They remained device-free, unless an adverse clinical event occurred mandating the reimplantation. The primary study endpoint was rate of sudden death and syncope after a 12-month follow-up. Among the 74 (39.4%) "low-risk" patients, a single patient suffered a bradycardia-related syncopal event corresponding to a 1.3% (95% CI, 0.0,3.9) rate of primary endpoint. Pacing systems were also reimplanted in 24 patients (32.4%) for syncope (n = 1), nonsevere bradycardia-reated symptoms (n = 17), cardiac resynchronization (n = 2), and for reassurance in 4 asymptomatic patients. Conclusion: After removal of infected pacing systems, these preliminary data demonstrated that a strategy of nonsystematic device reimplantation associated with close surveillance was safe in "low-risk" patients, allowing the administration of antimicrobials in a device-free state. (J Cardiovasc Electrophysiol, Vol. 21, pp. 540-544, May 2010) [source] Pyrotechnic Reaction Residue Particle AnalysisJOURNAL OF FORENSIC SCIENCES, Issue 2 2006Kenneth L. Kosanke Ph.D. ABSTRACT: Pyrotechnic reaction residue particle (PRRP) production, sampling and analysis are all very similar to that for primer gunshot residue. In both cases, the preferred method of analysis uses scanning electron microscopy to locate suspect particles and then uses energy dispersive x-ray spectroscopy to characterize the particle's constituent chemical elements. There are relatively few times when standard micro-analytical chemistry performed on pyrotechnic residues may not provide sufficient information for forensic investigators. However, on those occasions, PRRP analysis provides a greatly improved ability to discriminate between materials of pyrotechnic origin and other unrelated substances also present. The greater specificity of PRRP analysis is the result of its analyzing a large number of individual micron-sized particles, rather than producing only a single integrated result such as produced using standard micro-analytical chemistry. For example, PRRP analyses are used to demonstrate its ability to successfully (1) discriminate between pyrotechnic residues and unrelated background contamination, (2) identify that two different pyrotechnic compositions had previously been exploded within the same device, and (3) establish the chronology of an incident involving two separate and closely occurring explosions. [source] Fractional deep dermal ablation induces tissue tightening,LASERS IN SURGERY AND MEDICINE, Issue 2 2009Zakia Rahman MD Abstract Background and Objective Due to the significant risk profile associated with traditional ablative resurfacing, a safer and less invasive treatment approach known as fractional deep dermal ablation (FDDAÔ) was recently developed. We report the results of the first clinical investigation of this modality for treatment of photodamaged skin. Study Design/Materials and Methods Twenty-four subjects received treatments on the inner forearm with a prototype fractional CO2 laser device (Reliant Technologies Inc., Mountain View, CA) at settings of 5,40 mJ/MTZ and 400 MTZ/cm2. Clinical and histological effects were assessed by study investigators 1 week, 1 month, and 3 months following treatment. Thirty subjects were then enrolled in a multi-center study for treatment of photodamage using the same device. Subjects received 1,2 treatments on the face and neck, with energies ranging from 10 to 40 mJ/MTZ and densities ranging from 400 to 1,200 MTZ/cm2. Study investigators assessed severity of post-treatment responses during follow-up visits 48 hours, 1 week, 1 month, and 3 months following treatment. Using a standard quartile improvement scale (0,4), subjects and investigators assessed improvement in rhytides, pigmentation, texture, laxity and overall appearance 1 and 3 months post-treatment. Results Clinical and histologic results demonstrated that fractional delivery of a 10,600 nm CO2 laser source offers an improved safety profile with respect to traditional ablative resurfacing, while still effectively resurfacing epidermal and dermal tissue. Forearm and facial treatments were well-tolerated with no serious adverse events observed. Eighty-three percent of subjects exhibited moderate or better overall improvement (50,100%), according to study investigator quartile scoring. Conclusions FDDAÔ treatment is a safe and promising new approach for resurfacing of epidermal and deep dermal tissue targets. Lasers Surg. Med. 41:78,86, 2009. © 2009 Wiley-Liss, Inc. [source] Innovation zur Bestimmung der Erdstoff-Geokunststoff-Wechselwirkung , Pullout-, Scher- und ReibungsversucheBAUTECHNIK, Issue 9 2004Taner Aydogmus Dipl.-Ing. Der Einsatz des ökonomischen und ökologischen Baumaterials "Geokunststoff" hat sich in den letzten Jahren in der Geotechnik für das Bauwesen, den Bergbau und den Umweltschutz stark verbreitet. In Form von Geotextilien, Geogittern, Geomembranen und verwandten Produkten ermöglichen sie technisch einfache, preisgünstige alternative Lösungsmöglichkeiten. Für die Berechnung der Standsicherheit von Konstruktionen mit Geokunststoffen, die für Bewehrungszwecke verwendet werden, ist die Ermittlung der "Reibungseigenschaften" in den Schichtgrenzen zwischen verschiedenen Geokunststoffen sowie zwischen Geokunststoffen und Erdstoffen unerläßlich. Zur Einschätzung der Hauptversagensmechanismen eines kunststoffbewehrten Erdkörpers werden üblicherweise Scher- und Reibungsversuche sowie nun auch verstärkt Pullout-Versuche durchgeführt. In diesem Beitrag wird ein neu entwickeltes und gebautes vollautomatisches Großrahmenschergerät mit integrierter Herausziehversuchseinrichtung vorgestellt, welches die Durchführung von vielfältigen innovativen Versuchen, mit leicht reproduzierbaren , den in-situ-Verhältnissen anpaßbaren , Randbedingungen, dem aktuellen Stand der Versuchstechnik entsprechend und nach den Vorgaben der neuen Normen (z. B. DIN 18137-3) ermöglicht. Innovation for the determination of the soil-geosynthetic interaction , pullout-, shear- and friction tests. The use of the economical and ecological construction material "geosynthetic" plays a rapidly increasing role in a variety of civil engineering, mining and environmental protection applications. Geosynthetics captured their own place as construction material due to their diversity and their specific characteristics. The applications of geosynthetics are many-sided. In the form of geotextiles, geogrids, geomembranes and related products, they make technically simple and low-priced alternative solution concepts possible. For the stability analysis of geosynthetic constructions knowledge of the friction behaviour in the geosynthetic interfaces is essential. For the assessment of the main failure mechanisms of a geosynthetic reinforced construction shear- and friction tests are usually performed as well as now also Pullout tests. In the following, a novel experimental apparatus for the examination of the interaction behaviour of soil-geosynthetic compound systems capable of performing both pullout and direct shear tests is described. In comparison with known geosynthetic testing practice, the novel testing apparatus offers the special advantage that a wide range of innovative shear and pullout test procedures can be carried out in the same device with negligible influence of test device configurations on friction test results. [source] Carrier recombination processes in 1.3 ,m and 1.5 ,m InGaAs(P)-based lasers at cryogenic temperatures and high pressuresPHYSICA STATUS SOLIDI (B) BASIC SOLID STATE PHYSICS, Issue 14 2004S. J. Sweeney Abstract We describe measurements of the threshold current of 1.3 ,m and 1.5 ,m InGaAs(P)-based quantum-well lasers measured at cryogenic temperatures and at high pressures. At low temperatures (,100 K), we find that the threshold current of the devices increases with increasing pressure consistent with the calculated pressure variation of the radiative current. This is in sharp contrast with their pressure dependence at room temperature (RT), where the threshold current decreases with increasing pressure due to the decrease in importance of Auger recombination. These low-temperature, high-pressure results agree well with previous temperature dependence measurements on the same devices, which show a transition from radiative to non-radiative Auger recombination dominated behaviour as the laser temperature is increased from ,100 K to room temperature. (© 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source] | ||||||||||