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Autoimmune Thrombocytopenic Purpura (autoimmune + thrombocytopenic_purpura)

Distribution by Scientific Domains

Medical Sciences	100%

Selected Abstracts

Autoimmune thrombocytopenic purpura with spuriously normal platelet count and ,punch-hole' red cells

BRITISH JOURNAL OF HAEMATOLOGY, Issue 2 2007
Y. K. Lam
No abstract is available for this article. [source]

Splenunculectomy in autoimmune thrombocytopenic purpura

BRITISH JOURNAL OF HAEMATOLOGY, Issue 3 2003
Paul A. Fields
No abstract is available for this article. [source]

Clinically significant newly presenting autoimmune thrombocytopenic purpura in adults: a prospective study of a population-based cohort of 245 patients

BRITISH JOURNAL OF HAEMATOLOGY, Issue 6 2003
Annette J. Neylon
Summary. The true incidence and prognosis of autoimmune thrombocytopenic purpura (ITP) in adults is unknown. We present the results of a prospective study in a population-based cohort of newly presenting adults (, 16 years) with ITP and platelet count of <,50 × 109/l, which took place between 1 January 1993 and 31 December 1999 in the former Northern Health Region in the UK (population 3·08 million). A total of 245 cases were confirmed by bone marrow examination with a median follow-up of 60 months (range 6,78 months). There were 134 females/111 males (1·2:1). Overall incidence was 1·6 per 105 per annum. Absolute incidence was similar for both sexes, with highest age-specific incidence in those aged >,60 years. Thirty patients (12%) presented with frank bleeding, and 28% were asymptomatic. Forty-five patients (18%) received no treatment, and 135 (55%) received first-line treatment only. Thirty patients (12%) underwent splenectomy. There were four deaths (1·6%) from bleeding and/or the complications of therapy in this cohort, but only one was in the acute phase of the illness. The majority of patients (155 out of 245) achieved remission (platelet count >,100 × 109/l), with a further 59 (24%) in partial remission with no symptoms (platelet count 30,100 × 109/l). This population-based study suggests that the traditional view of adult ITP as being a predominantly chronic disease that preferentially affects females needs to be modified. [source]

Clopidogrel-associated autoimmune thrombocytopenic purpura

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, Issue 3 2004
Patricia J.M. Best MD
Abstract We report the case of a 51-year-old male who underwent coronary stent placement for the treatment of an acute myocardial infarction. One week later, he developed symptomatic autoimmune thrombocytopenia likely related to clopidogrel use. This was successfully treated with intravenous methylprednisilone and platelet transfusions. Catheter Cardiovasc Interv 2004;62:339,340. © 2004 Wiley-Liss, Inc. [source]