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Rose Hip (rose + hip)
Selected AbstractsA systematic review on the Rosa canina effect and efficacy profilesPHYTOTHERAPY RESEARCH, Issue 6 2008Cosima Chrubasik Abstract Rose hip, rose hip and seed and rose hip seed, all were negatively monographed by the German Commission E due to insufficient evidence of effects and effectiveness. Therefore a comprehensive review of the literature was conducted to summarize the pharmacological and clinical effects of Rosa canina L. to reevaluate its usefulness in traditional medicine. For various preparations of rose hip and rose hip and seed, antioxidative and antiinflammatory effects have been demonstrated. Lipophilic constituents are involved in those mechanisms of action. The proprietary rose hip and seed powder LitozinR has been employed successfully in a number of exploratory studies in patients suffering from osteoarthritis, rheumatoid arthritis and low back pain. However, the sizes of the clinical effects for the different indications need to be determined to assure clinical significance. There is also a rationale behind the use of LitozinR as part of a hypocaloric diet based on the rose hip probiotic, stool regulating and smooth muscle-relaxing actions, as well as the rose hip seed lipid-lowering, antiobese and antiulcerogenic effects. Further research is needed to clarify the importance of the reported promising experimental effects in clinical use and to characterize the optimum rose hip seed oil preparation for topical use in the treatment of skin diseases. Copyright © 2008 John Wiley & Sons, Ltd. [source] Patients with rheumatoid arthritis may benefit from a standardised powder of Rosa canina (rose hip)FOCUS ON ALTERNATIVE AND COMPLEMENTARY THERAPIES AN EVIDENCE-BASED APPROACH, Issue 2 2010Article first published online: 14 JUN 2010 [source] A one-year survey on the use of a powder from Rosa canina lito in acute exacerbations of chronic painPHYTOTHERAPY RESEARCH, Issue 9 2008C. Chrubasik Abstract This pilot surveillance included 152 patients with acute exacerbations of chronic pain, 124 (Back group) with non-specific low back pain (NSLBP), 20 with NSLBP overridden by osteoarthritic pain (Knee-Hip group), and eight with specific LBP (included in the safety analysis). Patients were recommended the rose hip and seed powder LitozinR at a dose providing up to 3 mg of galactolipid/day for up to 54 weeks. Clinical symptoms and well-being were assessed every 6 weeks. The patients also kept a diary of their pain and the requirement for rescue medication. Data were analysed by intention to treat with last observation carried forward. Only 77 patients completed the year of surveillance. Multivariate analysis suggested an appreciable overall improvement during the surveillance, irrespective of group, and this was reflected for most of the individual measures in repeated measures ANOVA. The degree and time-course of improvement echoed that seen in similar surveillances of patients receiving an aqueous extract of Harpagophytum. Multiple regression analyses indicated that percentage changes from baseline tended to be greater in patients with greater degrees of pain and disability, but were otherwise largely unrelated to the patients' characteristics. There were no serious adverse events. The rose hip and seed powder, LitozinR, seems to deserve further, more definitive studies as a possible option in long-term management of NSLBP with or without osteoarthritic pain. Copyright © 2008 John Wiley & Sons, Ltd. [source] A systematic review on the Rosa canina effect and efficacy profilesPHYTOTHERAPY RESEARCH, Issue 6 2008Cosima Chrubasik Abstract Rose hip, rose hip and seed and rose hip seed, all were negatively monographed by the German Commission E due to insufficient evidence of effects and effectiveness. Therefore a comprehensive review of the literature was conducted to summarize the pharmacological and clinical effects of Rosa canina L. to reevaluate its usefulness in traditional medicine. For various preparations of rose hip and rose hip and seed, antioxidative and antiinflammatory effects have been demonstrated. Lipophilic constituents are involved in those mechanisms of action. The proprietary rose hip and seed powder LitozinR has been employed successfully in a number of exploratory studies in patients suffering from osteoarthritis, rheumatoid arthritis and low back pain. However, the sizes of the clinical effects for the different indications need to be determined to assure clinical significance. There is also a rationale behind the use of LitozinR as part of a hypocaloric diet based on the rose hip probiotic, stool regulating and smooth muscle-relaxing actions, as well as the rose hip seed lipid-lowering, antiobese and antiulcerogenic effects. Further research is needed to clarify the importance of the reported promising experimental effects in clinical use and to characterize the optimum rose hip seed oil preparation for topical use in the treatment of skin diseases. Copyright © 2008 John Wiley & Sons, Ltd. [source] Evidence of effectiveness of herbal antiinflammatory drugs in the treatment of painful osteoarthritis and chronic low back painPHYTOTHERAPY RESEARCH, Issue 7 2007J. E. Chrubasik Abstract Treatment with herbal medicines is very popular in Europe. In order to get information on the evidence of effectiveness of oral herbal medicines in the treatment of pain in the joints or lower back, OVID(MEDLINE), PUBMED and COCHRANE COLLABORATION LIBRARY were searched back to 1985 for systematic reviews. The level of evidence of effectiveness was defined as strong , at least two confirmatory studies demonstrating a clinical relevant effect, moderate , one confirmatory study with a clinical relevant effect and/or multiple exploratory studies of good quality; otherwise the evidence was insufficient or conflicting in the case of inconsistent findings. Fifteen systematic reviews were identified. The evidence of effectiveness was strong for a proprietary unsaponifiable avocado soybean fraction and Harpagophytum preparations containing >50 mg harpagoside in the daily dosage, moderate for ginger and a proprietary rose hip and seed powder, insufficient for Boswellia serrata gum resin and other herbal preparations and inconsistent for a proprietary willow bark extract. Further rigorous studies are required to confirm the usefulness of herbal medicines in the treatment of osteoarthritic complaints and chronic low back pain in order to enable acceptance of the herbal medicines into the treatment guidelines. Copyright © 2007 John Wiley & Sons, Ltd. [source] Determination of phenolic compounds in rose hip (Rosa canina) using liquid chromatography coupled to electrospray ionisation tandem mass spectrometry and diode-array detectionRAPID COMMUNICATIONS IN MASS SPECTROMETRY, Issue 7 2002Erlend Hvattum Liquid chromatography coupled with negative and positive electrospray ionisation (ESI) tandem mass spectrometry (MS/MS) and diode-array detection (DAD) was used for determination of phenols in rose hip (Rosa canina) extract. ESI mass spectra of the chromatographically separated phenols gave the molecular weight of the compounds through prominent [M,,,H], ions for most of the compounds and M+ ions for the anthocyanins. Collision induced dissociation (CID) of the [M,,,H], (or M+) precursor ions yielded product ions which determined the molecular weight of the aglycones. In-source fragmentation followed by CID of the resulting deprotonated aglycone ([A,,,H],) provided product ions for the identification of the unconjugated phenols. The identification was based on comparison with product ion spectra of commercial standards. UV-diode-array spectra were used for identity confirmation. This combined approach allowed the identification in rose hip extract of an anthocyanin, i.e. cyanidin-3- O -glucoside, several glycosides of quercetin and glycosides of taxifolin and eriodictyol. Phloridzin was identified, and several conjugates of methyl gallate were also found, one of which was tentatively identified as methyl gallate-rutinoside. Catechin and quercetin were found as the aglycones in the extract. Copyright © 2002 John Wiley & Sons, Ltd. [source] Determination of cadmium and selected micronutrients in commonly used and traded medicinal plants in TurkeyJOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, Issue 1 2008Nazim Sekeroglu Abstract BACKGROUND: Medicinal plants commonly used and traded in Turkey were monitored for their cadmium and selected micronutrient (copper, iron, manganese and zinc) content. RESULTS: Cadmium was not detected in any sample of licorice extract, linden flowers or nettle leaves. However, in the rest of the samples, cadmium was found in the range of 7,126 µg kg,1, with the highest concentration in chamomile leaf. Of all the monitored trace elements, the highest concentration found was 520 mg kg,1 iron in zahter. The highest copper, manganese and zinc concentrations were found in rose hips (24 mg kg,1), Turkish oregano (58 mg kg,1) and zahter (50 mg kg,1), respectively. CONCLUSION: The results of the present study reveal that cadmium and trace element concentrations in medicinal plants commonly used as traditional medicines in Turkey are well below the critical levels. Copyright © 2007 Society of Chemical Industry [source] | |||||||||||||