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Recirculation
Kinds of Recirculation Terms modified by Recirculation Selected AbstractsLong-term performance of co-metabolic degradation of trichloroethylene in a fluidized bed reactor fed with benzene, toluene and xyleneJOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 4 2008Wei-Min Wu Abstract BACKGROUND: Trichloroethylene (TCE) can be degraded under aerobic condition with toluene and other aromatic compounds. Inhibition by primary substrates and toxicity of TCE oxidation influence TCE degradation. RESULTS: Long-term co-metabolic degradation of TCE was evaluated using a laboratory-scale fluidized bed reactor (12 L) with granular activated carbon (1.57 kg) as media and activated sludge as inoculum. The reactor was fed with TCE and a mixture of benzene, toluene and xylene (BTX) and operated with one-pass (hydraulic retention time (HRT) of 5,6 min) for 6 months and then with recirculation (HRT of 20,30 min) for 18 months. BTX/TCE-degrading biofilm was developed within 1 month. TCE was effectively degraded with influent TCE concentrations from 48 to 280 µg L,1. BTX inhibited TCE degradation. Recirculation (or long HRT) increased TCE removal efficiency from 30% with one-pass to 90%. BTX/TCE load ratio influenced TCE removal efficiency and TCE/BTX removal ratio. TCE degradation fitted first-order kinetics. The biomass grown in the reactor also degraded cis -1,2-dichloroethylene (DCE), trans -1,2-DCE and vinyl chloride efficiently except for 1,1-DCE. CONCLUSION: Co-metabolic degradation of TCE by BTX-degrading biomass from activated sludge is sustainable in the long term. BTX/TCE load ratio is a key parameter for TCE removal performance. Copyright © 2008 Society of Chemical Industry [source] Aerobic biological treatment of waste- waters containing dichloromethaneJOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 9 2007Sandra C Moura Abstract BACKGROUND: Volatilization has been advanced as one of the predominant phenomena contributing to volatile organic carbon emissions from wastewater treatment plants (WWTPs). In this study, strategies for minimizing such air stripping losses when treating a liquid stream containing dichloromethane (DCM), aiming at decreasing the overall emission inventory from WWTPs, were investigated. RESULTS: System R1, consisting of a continuous flow stirred tank reactor (CSTR) treating a liquid stream containing DCM at a concentration of 12 mmol dm,3 presented a biodegradation efficiency (BE) of 68%, based upon chloride release, with 10% of measurable losses, mainly due to volatilization, and 22% of unmeasurable losses. System R2 introduced operational designs aiming at decreasing DCM volatilization. In Experiment R2.1, a biotrickling filter, through which the air stripped from the CSTR was driven, was introduced leading to a reduction from 10% to 7% on the measurable losses. In Experiment R2.2, the air stripped from the CSTR was recirculated at a flow rate of 2.4 dm3 h,1 through the reactor medium before entering the biotrickling filter. The BE was improved from 69% to 82% and the losses associated with air stripping were successfully reduced to 2%. The proposed design, including air recirculation and the biotrickling filter, increased the ratio between the biodegradation rate and the volatilization rate from 7 to 41. CONCLUSIONS: Recirculation of the gaseous effluent through the reactor medium, which allowed for higher residence time within the bioreactor, was shown to be a successful strategy for improving the treatment process, thus minimizing DCM volatilization losses. Copyright © 2007 Society of Chemical Industry [source] A Microchemical System with Continuous Recovery and Recirculation of Catalyst-Immobilized Magnetic Particles,ANGEWANDTE CHEMIE, Issue 38 2010Dr. Chan, Pil Park Alles im Fluss: Ein mikromechanisches System für katalytische Durchflussreaktionen mit einem magnetischen Katalysator wird vorgestellt (siehe Bild). Der Mikroreaktor ermöglicht die automatische Abtrennung und Wiederzuführung von Katalysatorpartikeln und ist auf verschiedenste katalytische Reaktionen anwendbar. [source] Optimization of a single-effect evaporation system to effectively utilize thermal energyENVIRONMENTAL PROGRESS & SUSTAINABLE ENERGY, Issue 2 2009Raafat Alnaizy Abstract Wastewater treatment facilities at Emirates Gold in Dubai seek to improve the steam economy of the existing single-effect with recirculation and vapor-compression evaporation process. Maximizing steam economy is important as it impacts treatment costs. There are two main approaches for improving steam economy in evaporators. One is to use a multiple-effect evaporator; the other is to use a mechanical vapor recompression. Multiple-effect evaporators were rejected because of higher capital and power cost. One of the suggestions that were made towards improving the steam economy was to recover heat from the steam condensate. A modified process flow diagram was proposed and investigated. The modified process was simulated using SuperPro Designer and Hysys with complete material and energy balance computation. The modified process increased the total water evaporation capacity and gained 40% better steam economy of the process. Another advantage was an increase in the amount of water reused, which is both economical and environmentally friendly. © 2008 American Institute of Chemical Engineers Environ Prog, 2009 [source] Transient T,cell accumulation in lymph nodes and sustained lymphopenia in mice treated with FTY720EUROPEAN JOURNAL OF IMMUNOLOGY, Issue 12 2005Margaret Abstract FTY720 (2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) is an orally available immunomodulatory agent that induces severe peripheral blood lymphopenia. Most studies of these lymphopenic effects have been limited to short-term exposure to FTY720. FTY720 alters the ability of lymphocytes to respond to sphingosine-1-phosphate (S1P) through S1P receptors, particularly S1P1. FTY720 affects different leukocyte populations and their trafficking through major lymphoid organs. We show the dynamics of CD4,T, CD8,T, and B,lymphocyte recirculation in all major lymphoid compartments during 21-day FTY720 treatment of normal C57BL/6 mice. Following a transient increase in peripheral lymph nodes and Peyer's patches, lymphocyte recirculation reaches a new steady state. Other lymphoid organs show transient changes in lymphocyte composition with various patterns. At 21,days of FTY720 treatment, total body lymphocyte content is reduced by 20% and blood lymphocytes by 80%. Modeling suggests that the new steady state is due to a combination of reduced naive lymphocyte release from the thymus and a transient reduction of lymphocyte egress from lymph nodes. Our data indicate that the commonly held belief that FTY720 blocks lymphocyte egress from lymph nodes cannot fully explain the lymphocyte dynamics observed with prolonged treatment. [source] Postprandial lipemic response to alpha-linolenic acid rich oil, butter, and olive oilEUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, Issue 9 2010Julia Svensson Abstract Postprandial lipemia varies with composition of dietary fat due to partitioning of fatty acids between ,-oxidation, incorporation into TAG, and tissue lipids. Effects of alpha-linolenic acid (ALA) are poorly characterized. Lipase-catalyzed transesterification was used to produce a novel ALA-oil (35% ALA) from rapeseed and linseed oil. We hypothesized a lower postprandial lipemic response with ALA-oil than with olive oil and butter due to higher ,-oxidation of ALA. A randomized crossover study with 26 healthy men compared the effects on plasma lipids 7,h after a breakfast containing 35,g ALA-rich oil, butter fat, or olive oil. The incremental area under curve for plasma TAG was lower with butter than with olive oil (34%, p<0.05) and ALA-oil (25%, ns). After ALA-oil percentage ALA increased, in TAG to a constant level of 7,mol% and in NEFA to 6% after 7,h. Since total NEFA increased with time the amount of exogenous ALA in NEFA also increased. Butter resulted in lower postprandial lipemia than the oils, the difference exceeding what is expected from the presence of short and medium chain fatty acids in butter. There was a considerable recirculation of ALA into the NEFA pool available for oxidation. Practical application: Enzymatic transesterification was used to produce a dietary oil rich in ALA. By randomizing the partitioning of ALA more evenly between the TAG molecules the risk of oxidation could be reduced. Analyses showed that the ALA-oil was stable during storage for at least 3 months. Enzymatic transesterification could be used as an advantageous method to design an ALA rich dietary oil with new properties regarding fatty acid composition, susceptibility to oxidation, and effects on blood lipids. [source] Automated ultrasound-assisted method for the determination of the oxidative stability of virgin olive oilEUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, Issue 2 2007José Platero-López Abstract A fast and automated method is proposed for determining the oxidative stability of virgin olive oil by using ultrasound. The ultrasound microprobe (3,mm in diameter) was directly immersed into the olive oil sample contained in a test tube. The most influential variables in the oxidation process, namely pulse amplitude, duty cycle, irradiation time, and sample amount, were optimized. The oil absorbance at 270,nm was continuously monitored by oil recirculation through a 0.1-mm path length flow cell connected to a fiber optic microspectrometer. This short path length allowed the direct monitoring of absorbance without needing any sample dilution. The ultrasound energy was applied during 35,min, and the resulting increase in absorbance was continuously monitored. The difference between the final and the initial absorbance at 270,nm of a set of virgin olive oil samples was closely correlated with their oxidative stability calculated by the Rancimat method (R2,=,0.9915). The resulting equation enabled the prediction of the oxidative stability of virgin olive oil in a short period of time (35,min), by using a simple, inexpensive, automatic and easy-to-use system. [source] Larval transport and retention of the spiny lobster, Panulirus argus, in the coastal zone of the Florida Keys, USAFISHERIES OCEANOGRAPHY, Issue 5 2002Cynthia Yeung Abstract The spiny lobster Panulirus argus is of ecological and commercial importance in the South Florida coast of the continental USA and throughout the Intra-Americas Sea. Essential spiny lobster habitat in South Florida is primarily located in the Florida Keys coastal zone (including the Dry Tortugas), where the dynamic regional circulation coupled with the long planktonic larval duration (6,12 months) of P. argus raises questions of larval retention and recruitment. Locally spawned phyllosomata entrained in the Florida Current are likely to be expatriated out of the Straits of Florida, which implies that the local spiny lobster population is sustained by the transport of larval recruits from upstream locations. We examined the physical processes that may influence recruitment. Transport processes in the Keys coastal zone are spatially variable. Observed and modelled data suggest that the upper Keys is a point of onshore larval transport via the inshore meandering of the Florida Current, and the lower Keys to Dry Tortugas region apoint of retention through wind-driven onshore/countercurrents and eddy recirculation. Eddies that propagate between the Dry Tortugas and the lower Keys facilitate the exchange of larvae between the Florida Current and the coastal zone. Northerly wind events associated with cold fronts can enhance recirculation of larvae in the upper Keys. The association of older larvae with the Florida Current front supports the hypothesis that spiny lobster larval recruits come from upstream sources in the Caribbean. [source] A Screening Model for Injection-Extraction Treatment Well Recirculation System DesignGROUND WATER MONITORING & REMEDIATION, Issue 4 2008Monica Y. Wu Implementation of injection-extraction treatment well pairs for in situ, in-well, or on-site remediation may be facilitated by development and application of modeling tools to aid in hydraulic design and remediation technology selection. In this study, complex potential theory was employed to derive a simple one-step design equation and related type curves that permit the calculation of the extraction well capture zone and the hydraulic recirculation between an injection and extraction well pair oriented perpendicular to regional flow. This equation may be used to aid in the design of traditional fully screened injection-extraction wells as well as innovative tandem recirculating wells when an adequate geologic barrier to vertical ground water flow exists. Simplified models describing in situ bioremediation, in-well vapor stripping, and in-well metal reactor treatment efficiency were adapted from the literature and coupled with the hydraulic design equation presented here. Equations and type curves that combine the remediation treatment efficiency with the hydraulic design equation are presented to simulate overall system treatment efficiency under various conditions. The combined model is applied to predict performance of in situ bioremediation and in-well palladium reactor designs that were previously described in the literature. This model is expected to aid practitioners in treatment system screening and evaluation. [source] The effects of exercise during hemodialysis on adequacyHEMODIALYSIS INTERNATIONAL, Issue 1 2005C. Caner Pedalling during hemodialysis (HD) has been shown to increase solute clearance in a previous study. In the present study, we aimed to test whether an easy to perform exercise program, not requiring a special device, could yield similar outcomes. Fifteen HD patients with the mean age of 48.4 ± 3.8 years were enrolled into the study. Patients with significant access recirculation (>10%), moderate to severe coronary artery disease, moderate to severe heart failure, severe chronic obstructive lung disease, and history of lower extremity surgery during last three month period were excluded. All patients were studied on two consecutive HD sessions with identical prescriptions. At the first session, standard HD was applied without exercise, whereas in the second session lower extremity exercise of 30 minutes duration was added. Reduction rates and rebound for urea, creatinine, and potassium and Kt/V were calculated. Wilcoxon signed rank test was applied in analysis and p < 0.05 was accepted as significance level. All patients completed the study. When both sessions were compared, mean arterial blood pressure (97 ± 3 mmHg vs 120 ± 4 mmHg, p < 0.001) and heart rate (77 ± 1 beats/min vs 92 ± 3 beats/min, p < 0.001) were higher in the exercise group. On the other hand, urea reduction rates, rebound values of urea, creatinine, and potassium were similar in both groups. Conclusion:,In the study, we did not observe any changes in solute rebound and clearance with the exercise. Shorter duration of the exercise may be the explanation of failure to achieve desired outcomes. Increasing patients' tolerance and fitness levels by means of steadily increasing exercise programs may be of help. Additionally, mode of exercise may also be responsible for different outcomes. [source] Memory T-cell trafficking: new directions for busy commutersIMMUNOLOGY, Issue 2 2010Federica M. Marelli-Berg Summary The immune system is unique in representing a network of interacting cells of enormous complexity and yet being based on single cells travelling around the body. The development of effective and regulated immunity relies upon co-ordinated migration of each cellular component, which is regulated by diverse signals provided by the tissue. Co-ordinated migration is particularly relevant to the recirculation of primed T cells, which, while performing continuous immune surveillance, need to promptly localize to antigenic sites, reside for a time sufficient to carry out their effector function and then efficiently leave the tissue to avoid bystander damage. Recent advances that have helped to clarify a number of key molecular mechanisms underlying the complexity and efficiency of memory T-cell trafficking, including antigen-dependent T-cell trafficking, the regulation of T-cell motility by costimulatory molecules, T-cell migration out of target tissue and fugetaxis, are reviewed in this article. [source] Composite adaptive and input observer-based approaches to the cylinder flow estimation in spark ignition automotive enginesINTERNATIONAL JOURNAL OF ADAPTIVE CONTROL AND SIGNAL PROCESSING, Issue 2 2004A. Stotsky Abstract The performance of air charge estimation algorithms in spark ignition automotive engines can be enhanced using advanced estimation techniques available in the controls literature. This paper illustrates two approaches of this kind that can improve the cylinder flow estimation for gasoline engines without external exhaust gas recirculation (EGR). The first approach is based on an input observer, while the second approach relies on an adaptive estimator. Assuming that the cylinder flow is nominally estimated via a speed-density calculation, and that the uncertainty is additive to the volumetric efficiency, the straightforward application of an input observer provides an easy to implement algorithm that corrects the nominal air flow estimate. The experimental results that we report in the paper point to a sufficiently good transient behaviour of the estimator. The signal quality may deteriorate, however, for extremely fast transients. This motivates the development of an adaptive estimator that relies mostly on the feedforward speed-density calculation during transients, while during engine operation close to steady-state conditions, it relies mostly on the adaptation. In our derivation of the adaptive estimator, the uncertainty is modelled as an unknown parameter multiplying the intake manifold temperature. We use the tracking error between the measured and modelled intake manifold pressure together with an appropriately defined prediction error estimate to develop an adaptation algorithm with improved identifiability and convergence rate. A robustness enhancement, via a ,-modification with the ,-factor depending on the prediction error estimate, ensures that in transients the parameter estimate converges to a pre-determined a priori value. In close to steady-state conditions, the ,-modification is rendered inactive and the evolution of the parameter estimate is determined by both tracking error and prediction error estimate. Further enhancements are made by incorporating a functional dependence of the a priori value on the engine operating conditions such as the intake manifold pressure. The coefficients of this function can be learned during engine operation from the values to which the parameter estimate converges in close to steady-state conditions. This feedforward learning functionality improves transient estimation accuracy and reduces the convergence time of the parameter estimate. Copyright © 2004 John Wiley & Sons, Ltd. [source] Energy efficiency improvement strategies for a diesel engine in low-temperature combustionINTERNATIONAL JOURNAL OF ENERGY RESEARCH, Issue 1 2009Ming Zheng Abstract The lowered combustion temperature in diesel engines is capable of reducing nitrogen oxides and soot simultaneously, which can be implemented by the heavy use of exhaust gas recirculation (EGR) or the homogeneous charge compression ignition (HCCI) type of combustion. However, the fuel efficiency of the low-temperature combustion (LTC) cycles is commonly compromised by the high levels of hydrocarbon and carbon monoxide emissions. More seriously, the scheduling of fuel delivery in HCCI engines has lesser leverage on the exact timing of auto-ignition that may even occur before the compression stroke is completed, which may cause excessive efficiency reduction and combustion roughness. New LTC control strategies have been explored experimentally to achieve ultralow emissions under independently controlled EGR, intake boost, exhaust backpressure, and multi-event fuel-injection events. Empirical comparisons have been made between the fuel efficiencies of LTC and conventional diesel cycles. Preliminary adaptive control strategies based on cylinder pressure characteristics have been implemented to enable and stabilize the LTC when heavy EGR is applied. The impact of heat-release phasing, duration, shaping, and splitting on the thermal efficiency has also been analyzed with engine cycle simulations. This research intends to identify the major parameters that affect diesel LTC engine thermal efficiency. Copyright © 2008 John Wiley & Sons, Ltd. [source] Influence of high rates of supplemental cooled EGR on NOx and PM emissions of an automotive HSDI diesel engine using an LP EGR loopINTERNATIONAL JOURNAL OF ENERGY RESEARCH, Issue 15 2008A. Maiboom Abstract Previous experimental studies on diesel engine have demonstrated the potential of exhaust gas recirculation (EGR) as an in-cylinder NOx control method. Although an increase in EGR at constant boost pressure (substitution EGR) is accompanied with an increase in particulate matter (PM) emissions in the conventional diesel high-temperature combustion (HTC), the recirculation of exhaust gases supplementary to air inlet gas (supplemental EGR) by increasing the boost pressure has been suggested as a way to reduce NOx emissions while limiting the negative impact of EGR on PM emissions. In the present work, a low-pressure (LP) EGR loop is implemented on a standard 2.0 l automotive high-speed direct injection (HSDI) turbocharged diesel engine to study the influence of high rates of supplemental cooled EGR on NOx and PM emissions. Contrary to initial high-pressure (HP) EGR loop, the gas flow through the turbine is unchanged while varying the EGR rate. Thus, by closing the variable geometry turbine (VGT) vanes, higher boost pressure can be reached, allowing the use of high rates of supplemental EGR. Furthermore, recirculated exhaust gases are cooled under 50°C and water vapour is condensed and taken off from the recirculated gases. An increase in the boost pressure at a given inlet temperature and dilution ratio (DR) results in most cases an increase in NOx emissions and a decrease in PM emissions. The result of NOx,PM trade-off, while varying the EGR rate at fixed inlet temperature and boost pressure depends on the operating point: it deteriorates at low load conditions, but improves at higher loads. Further improvement can be obtained by increasing the injection pressure. A decrease by approximately 50% of NOx emissions while maintaining PM emission level, and brake specific fuel consumption can be obtained with supplemental cooled EGR owing to an LP EGR loop, compared with the initial engine configuration (HP moderately cooled EGR). Copyright © 2008 John Wiley & Sons, Ltd. [source] Effects of exhaust gas recirculation on exergy destruction due to isobaric combustion for a range of conditions and fuelsINTERNATIONAL JOURNAL OF ENERGY RESEARCH, Issue 10 2008Hari Shanker Sivadas Abstract This study was directed at examining the effects of exhaust gas recirculation (EGR) on the exergy destroyed due to combustion in a simple constant pressure combustion system. Both cooled and adiabatic cases of EGR were studied. Higher ,cooled EGR' fractions lead to higher exergy destruction for reactant temperatures less than 2000,K. For the base case, the percentage of the reactant exergy destroyed for 0,,20, and 40% EGR at 300,K was found to be 28,,32, and 36%, respectively. Neglecting the chemical exergy in the products, the equivalence ratio and reactant temperature that corresponded to the lowest exergy destruction varied from 0.9 to 1.0 and 800,1300,K, respectively, depending on the EGR fraction. The fraction of the reactant exergy destroyed increased with increase in the molecular mass of the fuel for the alkanes examined. The exergy destroyed due to combustion was the least for acetylene and the highest for the alcohols. The trends stayed the same for the different EGR fractions for the eight fuels that were analyzed. For the ,adiabatic EGR' case, the percentage destruction of exergy decreased with increase in the EGR fraction with a 40% ,adiabatic EGR' fraction corresponding to a destruction of exergy of 14%. Copyright © 2008 John Wiley & Sons, Ltd. [source] Comparative study of flame structures and NOx emission characteristics in fuel injection recirculation and fuel gas recirculation combustion systemINTERNATIONAL JOURNAL OF ENERGY RESEARCH, Issue 10 2004Jeong Park Abstract A numerical study with momentum-balanced boundary conditions has been conducted to grasp the chemical effects of added CO2 to fuel- and oxidizer-sides on flame structure and NO emission behaviour in H2,O2 diffusion flames with varying flame location. A reaction mechanism is proposed to show better agreements with experimental results in CO2 -added hydrogen flames. Oxidizer-side dilution results in significantly higher flame temperatures and NO emission. Flame location is dramatically changed due to high diffusivity of hydrogen according to variation of the composition of fuel- and oxidizer-sides. This affects flame structure and NO emission considerably especially the chemical effects of added CO2. The present work also displays separately thermal contribution and prompt NO emission due to the chemical effects caused by thermal dissociation of added CO2 in NO emission behaviour. It is found that flame temperature and the flame location affect the contribution of thermal and prompt NO due to chemical effects considerably in NO emission behaviour. Copyright © 2004 John Wiley & Sons, Ltd. [source] Role of cell adhesion molecules in leukocyte recruitment in the liver and gutINTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Issue 1 2003A. Ala Summary. This article reviews the evidence that adhesion molecules are critical in leukocyte recirculation and pathogenesis of diseases affecting the closely related tissues of the liver and gut, which offer novel opportunities for treatment. [source] Pressure and temperature-based adaptive observer of air charge for turbocharged diesel enginesINTERNATIONAL JOURNAL OF ROBUST AND NONLINEAR CONTROL, Issue 6 2004A. G. Stefanopoulou Abstract In this paper we design an adaptive air charge estimator for turbocharged diesel engines using intake manifold pressure, temperature and engine speed measurements. This adaptive observer scheme does not depend on mass air flow sensors and can be applied to diesel engines with no exhaust gas recirculation (EGR). The performance of the adaptive scheme is shown in simulations to be comparable to conventional air charge estimation schemes if perfect temperature measurements are available. The designed scheme cannot estimate fast transients and its performance deteriorates with temperature sensor lags. Despite all these difficulties, this paper demonstrates that (i) the proposed scheme has better robustness to modelling errors because it provides a closed-loop observer design, and (ii) robust air charge estimation is achievable even without air flow sensors if good (fast) temperature sensors become available. Finally, we provide a rigorous proof and present the implementation challenges as well as the limiting factors of this adaptation scheme and point to hardware and temperature sensor requirements. Copyright © 2004 John Wiley & Sons, Ltd. [source] Long-term performance of co-metabolic degradation of trichloroethylene in a fluidized bed reactor fed with benzene, toluene and xyleneJOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 4 2008Wei-Min Wu Abstract BACKGROUND: Trichloroethylene (TCE) can be degraded under aerobic condition with toluene and other aromatic compounds. Inhibition by primary substrates and toxicity of TCE oxidation influence TCE degradation. RESULTS: Long-term co-metabolic degradation of TCE was evaluated using a laboratory-scale fluidized bed reactor (12 L) with granular activated carbon (1.57 kg) as media and activated sludge as inoculum. The reactor was fed with TCE and a mixture of benzene, toluene and xylene (BTX) and operated with one-pass (hydraulic retention time (HRT) of 5,6 min) for 6 months and then with recirculation (HRT of 20,30 min) for 18 months. BTX/TCE-degrading biofilm was developed within 1 month. TCE was effectively degraded with influent TCE concentrations from 48 to 280 µg L,1. BTX inhibited TCE degradation. Recirculation (or long HRT) increased TCE removal efficiency from 30% with one-pass to 90%. BTX/TCE load ratio influenced TCE removal efficiency and TCE/BTX removal ratio. TCE degradation fitted first-order kinetics. The biomass grown in the reactor also degraded cis -1,2-dichloroethylene (DCE), trans -1,2-DCE and vinyl chloride efficiently except for 1,1-DCE. CONCLUSION: Co-metabolic degradation of TCE by BTX-degrading biomass from activated sludge is sustainable in the long term. BTX/TCE load ratio is a key parameter for TCE removal performance. Copyright © 2008 Society of Chemical Industry [source] Aerobic biological treatment of waste- waters containing dichloromethaneJOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 9 2007Sandra C Moura Abstract BACKGROUND: Volatilization has been advanced as one of the predominant phenomena contributing to volatile organic carbon emissions from wastewater treatment plants (WWTPs). In this study, strategies for minimizing such air stripping losses when treating a liquid stream containing dichloromethane (DCM), aiming at decreasing the overall emission inventory from WWTPs, were investigated. RESULTS: System R1, consisting of a continuous flow stirred tank reactor (CSTR) treating a liquid stream containing DCM at a concentration of 12 mmol dm,3 presented a biodegradation efficiency (BE) of 68%, based upon chloride release, with 10% of measurable losses, mainly due to volatilization, and 22% of unmeasurable losses. System R2 introduced operational designs aiming at decreasing DCM volatilization. In Experiment R2.1, a biotrickling filter, through which the air stripped from the CSTR was driven, was introduced leading to a reduction from 10% to 7% on the measurable losses. In Experiment R2.2, the air stripped from the CSTR was recirculated at a flow rate of 2.4 dm3 h,1 through the reactor medium before entering the biotrickling filter. The BE was improved from 69% to 82% and the losses associated with air stripping were successfully reduced to 2%. The proposed design, including air recirculation and the biotrickling filter, increased the ratio between the biodegradation rate and the volatilization rate from 7 to 41. CONCLUSIONS: Recirculation of the gaseous effluent through the reactor medium, which allowed for higher residence time within the bioreactor, was shown to be a successful strategy for improving the treatment process, thus minimizing DCM volatilization losses. Copyright © 2007 Society of Chemical Industry [source] Studies on internal and external water treatment at a paper and cardboard factoryJOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 5 2003Mamdouh M Nassar Abstract The treatment of effluent from a paper/board factory that produced 280 tons of cardboard and consumed 1200 m3 of water per day was carried out. Wastewater analysis showed that the mill effluent contained 3000 mg dm,3 suspended solids, 1400 mg dm,3 COD (chemical oxygen demand) and 500 mg dm,3 BOD (biochemical oxygen demand). An internal treatment cycle is suggested that involves recirculation of paper-machine wastewater (white-water) and may be accomplished by installing a flotation saveall (fiber recovery) unit. This arrangement reduced fresh water use by about 90%, reduced fiber loss by 80,90%, and increased board production by 13%. An external treatment process for the effluent was assessed by conducting laboratory coagulation tests (alum, ferric chloride, ferrous sulfate, and polyelectrolyte) on the whole mill effluent. Oxidation of the mill effluent using calcium hypochlorite before discharging the effluent to a lagoon offers the benefits of killing the harmful bacteria and reducing the pollution load. Copyright © 2003 Society of Chemical Industry [source] Perfusion parameters derived from bolus-tracking perfusion imaging are immune to tracer recirculation,JOURNAL OF MAGNETIC RESONANCE IMAGING, Issue 3 2010Jayme Cameron Kosior PhD Abstract Purpose: To investigate the impact of tracer recirculation on estimates of cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT). Materials and Methods: The theoretical model used to derive CBF, CBV, and MTT was examined. CBF and CBV estimates with and without tracer recirculation were compared in computer simulations to examine the effects of tracer recirculation. Results: The equations used to derive CBF, CBV, and MTT assume that the arterial input function and tissue tracer signals define the input and output signals, respectively, of a linear time-invariant system. As a result of the principle of superposition, these perfusion parameters are immune to tracer recirculation, which was confirmed by computer simulation. However, limited acquisition durations can lead to CBV and CBF errors of up to 50%. Conclusion: Tracer recirculation does not impact estimation of CBF, CBV, or MTT. However, previous approaches used to remove recirculation effects may be beneficial when used to compensate for limited acquisition durations in which the passage of the bolus is not adequately captured. J. Magn. Reson. Imaging 2010;31:753,756. © 2010 Wiley-Liss, Inc. [source] Discrete element simulation of free flowing grains in a four-bladed mixerAICHE JOURNAL, Issue 8 2009Brenda Remy Abstract Numerical simulations of granular flow in a cylindrical vessel agitated by a four-blade impeller were performed using the discrete element method. Velocity, density, and stress profiles within the mixer displayed a periodic behavior with a fluctuation frequency equal to that of the blade rotation. Blade orientation was found to affect flow patterns and mixing kinetics. For an obtuse blade pitch orientation, a three-dimensional recirculation zone develops in-front of the blade due to formation of heaps where the blades are present. This flow pattern promotes vertical and radial mixing. No recirculation zone was observed when the blade orientation was changed to an acute blade pitch. The system's frictional characteristics are shown to strongly influence the granular behavior within the mixer. At low friction coefficients, the 3-D recirculation in front of the obtuse blade is not present reducing convective mixing. Higher friction coefficients lead to an increase in granular temperature which is associated with an increase in diffusive mixing. Normal and shear stresses were found to vary with mixer height with maximum values near the bottom plate. Additionally, a strong dependence between the magnitude of the shear stresses and the friction coefficient of the particles was found. The stress tensor characteristics indicate that the granular flow in our simulations occurs in the quasi-static regime. At the same time, the averaged pressure was found to vary linearly with bed height and could be predicted by a simple hydrostatic approximation. © 2009 American Institute of Chemical Engineers AIChE J, 2009 [source] Comparing flow-reversal and inner recirculation reactors: Experiments and simulationsAICHE JOURNAL, Issue 7 2003Moshe Ben-Tullilah The operation of reactors with flow reversal operate similar to a reactor with internal recirculation, which the feed enters through one (say, inner) reactor and then turns around and flows out through (the outer) another, when the heat-transfer coefficient between the tubes is large. In this study, we compare the behavior of a packed-bed reactor operating in flow-reversal or internal-recirculation modes, using ethylene oxidation on Pt/Al2O3 as a model reaction. The reactor was built from two concentric tubes (with 28.5 and 42.5 mm in diameter), both packed with a 20 cm catalytic bed and 10 cm inert beds (of alumina-pellets) on each side. An adjustable opening between the tubes allowed for an internal recycle mode and the whole system could be operated with periodic flow reversal. The reactor can be employed then either as a simple once-through bed or as a bed with flow reversal in the inner tube or as bed with internal recirculation flowing from the inner to outer tube, or in the opposite direction, as well as an internal-recirculation reactor with flow reversal. Due to heat losses, the latter two modes were inferior to the others. The experiments, backed by simulations using a homogeneous model with independently determined parameters, showed that the technically-simpler inner-outer internal-recycle reactor operated better at low flow rates, than that with flow reversal, but the conclusion is reversed at high flow rates. The domain where the internal-recirculation reactor is superior depends on the heat-transfer coefficient between the streams. By lowering the feed concentration, the extinction point was determined for each mode highlighting again the conclusions drawn above that inner-recirculation operation may be superior to flow reversal at low flow rates. Simulations revealed also the existence of solutions with stationary fronts or oscillatory fronts. [source] Prediction of the possibility of the second peak of drug plasma concentration time curve after iv bolus administration from the standpoint of the traditional multi-compartmental linear pharmacokineticsJOURNAL OF PHARMACEUTICAL SCIENCES, Issue 6 2008Leonid M. Berezhkovskiy Abstract It is shown that the existence of the second peak on the drug plasma concentration time curve Cp(t) after iv bolus dosing can be explained by considering the traditional multi-compartmental linear pharmacokinetics. It was found that a direct solution of the general three-compartment model yields the second peak of Cp(t) for the certain values of the rate constants, and Cp(t) includes the term with oscillating preexponent, that is, K,sin(,t,+,,),exp(,,t), in this case. The considered model describes the drug entero-hepatic recirculation in the species which do not have gall bladder (rats). The model fit of the experimental data from rat pharmacokinetic studies where the second peak of Cp(t) was observed, yields the rate of bile production that is consistent with the physiological value (,0.7 mL/h). © 2007 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 97:2385,2393, 2008 [source] In vivo pharmacology and antidiarrheal efficacy of a thiazolidinone CFTR inhibitor in rodentsJOURNAL OF PHARMACEUTICAL SCIENCES, Issue 1 2005N.D. Sonawane Abstract A small-molecule inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR), 3-[(3-trifluoromethyl)phenyl]-5-[(4-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone (CFTRinh -172), reduces enterotoxin-induced intestinal fluid secretion in rodents. Here, we study CFTRinh -172 pharmacology and antidiarrheal efficacy in rodents using 14C-labeled CFTRinh -172, liquid chromatography/mass spectrometry, and a closed intestinal loop model of fluid secretion. CFTRinh -172 was cleared primarily by renal glomerular filtration without chemical modification. CFTRinh -172 accumulated in liver within 5 min after intravenous infusion in mice, and was concentrated fivefold in bile over blood. At 30,240 min, CFTRinh -172 was found mainly in liver, intestine, and kidney, with little detectable in the brain, heart, skeletal muscle, or lung. Pharmacokinetic analysis in rats following intravenous bolus infusion showed a distribution volume of 770 mL with redistribution and elimination half-times of 0.14 h and 10.3 h, respectively. CFTRinh -172 was stable in hepatic microsomes. Closed-loop studies in mice indicated that a single intraperitoneal injection of 20 ,g CFTRinh -172 inhibited fluid accumulation at 6 h after cholera toxin by >90% in duodenum and jejunum, ,60% in ileum and <10% in colon. No toxicity was seen after high-dose CFTRinh -172 administration (3 mg/kg/day in two daily doses) in mice over the first 6 weeks of life. The metabolic stability, enterohepatic recirculation, slow renal elimination, and intestinal accumulation of CFTRinh -172 account for its efficacy as an antidiarrheal. © 2004 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 94:134,143, 2005 [source] RECIRCULATING WELLS: GROUND WATER REMEDIATION AND PROTECTION OF SURFACE WATER RESOURCES,JOURNAL OF THE AMERICAN WATER RESOURCES ASSOCIATION, Issue 1 2000Keith W. Ryan ABSTRACT: Several chlorinated solvent plumes threaten the sole-source aquifer underlying the Massachusetts Military Reservation at the western end of Cape Cod. Sensitive surface water features including ponds, cranberry bogs, and coastal wetlands are hydraulically connected to the aquifer. For one of the plumes (CS-10 the original remedy of 120 extraction and reinjection wells has the potential for significant disruption of surface water hydrology, through the localized drawdown and mounding of the water table. Recirculating wells with in-well air stripping offer a cost-effective alternative to conventional pump-and-treat technology that does not adversely affect the configuration of the water table. Pilot testing of a two well system, pumping 300 gpm, showed a capture radius of > 200 feet per well, in-well trichloroethylene (TCE) removal efficiencies of 92 to 98 percent per recirculation cycle, an average of three recirculation cycles within the capture zone, and no measurable effect on water table elevations at any point within the recirculation/treatment zone. During 120 days of operation, the mean concentration of TCE in the treatment zone was reduced by 83 percent, from 1,111 ,g/l to 184 ,g/l. Full-scale design projections indicate that 60 wells at an average spacing of 160 feet, having an aggregate recirculation 11 MGD, can contain the CS-b plume without ground water extraction or adverse hydraulic effects on surface water resources. The estimated capital costs for such a system are about $7 million, and annual operations-and-maintenance costs should be about $1.4 million, 40 percent of those associated with a pump and treat system over a 20-year period. [source] The Coxib NSAIDs: Potential Clinical and Pharmacologic Importance in Veterinary MedicineJOURNAL OF VETERINARY INTERNAL MEDICINE, Issue 5 2005Mary Sarah Bergh Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to control acute and chronic pain as well as to manage oncologic and neurologic diseases in human and veterinary patients. Despite ongoing research and efforts to improve the safety and efficacy of existing drugs, adverse effects such as gastrointestinal irritation, renal and hepatic toxicity, interference with hemostasis, and reproductive problems persist. The true incidence of NSAID-induced adverse effects in animals is unknown, but is likely underestimated, because cats and dogs may be more sensitive than humans to NSAIDs due to alterations in drug metabolism, absorption, and enterohepatic recirculation. NSAIDs produce both analgesia and toxic adverse effects primarily by inhibiting cyclooxygenase (COX), thereby decreasing the production of prostaglandins that signal inflammation and pain as well as mediate physiologic functions such as platelet aggregation, gastric protection, and electrolyte balance in the kidney. The presence of at least 2 COX isoforms may account for variability in NSAID efficacy and toxicity both within and among species. This paper reviews and evaluates the published literature on the safety, pharmacology, uses, and complications of a subclass of COX-1,sparing drugs, the coxibs, in veterinary medicine. Coxibs and other COX-1,sparing drugs provide a clinically useful improvement over traditional NSAIDs, but data are incomplete and more in vivo species-specific, target-tissue, and clinical studies are needed. [source] Influence of novel cycle concepts on the high-temperature corrosion of power plantsMATERIALS AND CORROSION/WERKSTOFFE UND KORROSION, Issue 5 2008Bettina BordenetArticle first published online: 29 MAY 200 Abstract The aim to reduce CO2 emissions has triggered the evaluation of new cycle concepts for power plants. CO2 -capture concepts are also evaluated to add on new and existing power plants. For combined cycle power plants (CCPP), different cycles are investigated such as integrated gasification (IGCC) or oxy-fuel firing. Besides the difference in combustion compared to a conventional CCPP, the environmental boundary conditions are changed and will affect the oxidation and corrosion life of the materials in the hot-gas path of the gas turbine and the heat-recovery steam generator. For the circulating fluidised bed power plants, the biomass co-firing and the oxy-fuel firing are also foreseen for CO2 -emission reduction. The fireside corrosion of the water walls will be influenced by these concepts and the changed fuel. The corrosion risk has been evaluated for two new power plant concepts: combined cycle with exhaust gas recirculation and pulverised coal-fired boiler with oxy-fuel firing. Based on this evaluation, the consequences for the testing conditions and the material selection have been discussed in detail. [source] Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25, T cells from atopic and nonatopic donorsALLERGY, Issue 8 2009D. Ahern Background:, Allergic inflammation is associated with Th2-type T cells, which can be suppressed by CD4+ CD25+ regulatory T cells (Tregs). Both express chemokine receptors (CCR) 4 and CCR8, but the dynamics of expression and effect of atopic status are unknown. Objective:, To examine the expression of chemokine receptors by CD4+ CD25+ and CD4+ CD25, T cells from atopic and nonatopic donors, and document response to allergen stimulation in vitro. Methods:, Chemokine receptor expression was examined by flow cytometry and quantitative PCR of CD4+ CD25hi and CD4+ CD25, T cells from atopics and nonatopics. Responsiveness to chemokines was by actin polymerization. Dynamics of chemokine receptor expression in 6-day allergen-stimulated cultures was analysed by carboxyfluoroscein succinimidyl ester labelling. Results:, CD4+ CD25hi Tregs preferentially expressed CCR3, CCR4, CCR5, CCR6 and CCR8. CD4+ CD25hi Tregs responded to the chemokine ligands for CCR4, CCR6 and CCR8 (CCL17, 22, 20 and 1 respectively), with no differences between atopic and nonatopic donors. Over 6-day allergen stimulation, CD4+ CD25+ T-cells downregulated CCR4 and upregulated CCR7, in contrast to CD4+ CD25, effector cells, which downregulated CCR7 and upregulated CCR4. Conclusions:, CCR4, CCR6 and CCR8 have potential roles in localization of both CD4+ CD25+ regulatory and CD4+ CD25, effector T cells to sites of allergic inflammation. Upregulation of CCR7 and downregulation of CCR4 upon allergen stimulation of Tregs may allow their recirculation from sites of inflammation, in contrast to retention of effector T cells. [source] | ||||||||||||||||||||||||||||||||||