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Quinoline Derivatives (quinoline + derivative)
Selected AbstractsThe First Proline-Catalyzed Friedlander Annulation: Regioselective Synthesis of 2-Substituted Quinoline DerivativesEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 16 2008Biao Jiang Abstract The first proline-catalyzed Friedlander annulation for the synthesis of 2-substituted 4-trifluoromethyl quinoline derivatives is described. Excellent regioselectivity as well as good yields were shown in a variety of cases, and a tandem aldol-cyclization pathway might be involved. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) [source] Synthesis of New Quinoline Derivatives as Inhibitors of Human Tumor Cells GrowthARCHIV DER PHARMAZIE, Issue 8 2010Aymn E. Rashad Abstract A series of new 8-[(2H -tetrazol-5-yl)methoxy]quinoline derivatives, their sugar hydrazones, and their N -glycoside derivatives were synthesized. Furthermore, the 1,2,4-triazole-3-one derivatives 3 and 4 were synthesized from the amidrazone derivative 2. Some of the newly prepared compounds demonstrated inhibitory effects on the growth of MCF-7 human breast cancer cells as compared with the activity of the commonly used anticancer drug, cisplatin. The results of antitumor evaluation revealed that compounds 2,5, 8b, and 12 inhibited the growth of cancer cells through their effect as free-radical regulators by increasing the activity of superoxide dismutase and depletion of intracellular levels of reduced glutathione, catalase and glutathione peroxidase activities, accompanied with a high production of hydrogen peroxide, nitric oxide, and other free radicals causing the killing of tumor cells. The results suggested that the prepared compounds possess significant anticancer activity comparable to cisplatin and the antitumor activity of these prepared compounds was accompanied with a reduction in the levels of protein and nucleic acids. [source] ChemInform Abstract: Unexpected Domino Reaction via Pd-Catalyzed Sonogashira Coupling of Benzimidoyl Chlorides with 1,6-Enynes and Cyclization to Synthesize Quinoline Derivatives.CHEMINFORM, Issue 24 2010Guo-Lin Gao Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis and Pharmacological Studies on Some Phthalimidoxy Substituted Quinoline Derivatives.CHEMINFORM, Issue 16 2010Dinesh Bhambi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Zinc-Catalyzed Reactions of Ethenetricarboxylates with 2-(Trimethylsilylethynyl)anilines Leading to Bridged Quinoline Derivatives.CHEMINFORM, Issue 46 2009Shoko Yamazaki Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Quinoline Derivatives by Cyclocondensation of N-(2-Bromophenylmethylphenyl)benzenesulfonamide with Enol Ethers and Enamines.CHEMINFORM, Issue 29 2009Giuseppe Cremonesi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Sequential Catalytic Process: Synthesis of Quinoline Derivatives by AuCl3/CuBr-Catalyzed Three-Component Reaction of Aldehydes, Amines, and Alkynes.CHEMINFORM, Issue 38 2008Fengping Xiao Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Synthesis and Characterization of Quinoline Derivatives via the Friedlaender Reaction.CHEMINFORM, Issue 46 2007Dingqiao Yang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Lewis Acid Promoted Aza Diels,Alder Reactions of Acyclic Unactivated 5-Dienyl Pyrimidinones with N-Arylimines: Synthesis of Novel Quinoline Derivatives.CHEMINFORM, Issue 28 2007Gaurav Bhargava Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Transformations of 2-(,-Furyl)-4-(2-oxopyrrolidinyl-1)-1,2,3,4-tetrahydroquinolines, Cycloadducts of the Imino Diels,Alder Reaction: A Simple Synthesis of New Quinoline Derivatives.CHEMINFORM, Issue 15 2007Vladimir V. Kouznetsov Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] A Simple and Clean Procedure for the Synthesis of Polyhydroacridine and Quinoline Derivatives: Reaction of Schiff Base with 1,3-Dicarbonyl Compounds in Aqueous Medium.CHEMINFORM, Issue 5 2006Xiang-Shan Wang No abstract is available for this article. [source] Synthesis of Aryl-Substituted Quinoline Derivatives via Broensted Acid-Catalyzed [4 + 2] Aza Diels,Alder Reaction.CHEMINFORM, Issue 49 2004Takahiko Akiyama Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: Synthesis of Thiosulfonates Belonging to Quinoline Derivatives.CHEMINFORM, Issue 16 2001V. I. Lubenets Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Syntheses and Cytotoxic, Antimicrobial, Antifungal, and Cardiovascular Activity of New Quinoline Derivatives.CHEMINFORM, Issue 4 2001Kalid Mohammed Khan Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: An Efficient Synthesis of Indeno[1,2-b]pyridine and Benzo[h]quinoline Derivatives under Solvent-Free Conditions.CHEMINFORM, Issue 41 2009Liangce Rong Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis of Benzo[f]quinoline Derivatives by Three-Component Condensation of Tetronic Acid with Naphthalen-2-amine and Formaldehyde.CHEMINFORM, Issue 37 2009A. P. Kadutskii Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: An Efficient Synthesis of Pyrimido[4,5-b]quinoline Derivatives via Three-Component Reaction in Aqueous Media.CHEMINFORM, Issue 36 2009Da-Qing Shi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Design and Synthesis of 5-Alkoxy-[1,2,4]triazolo[4,3-a]quinoline Derivatives with Anticonvulsant Activity.CHEMINFORM, Issue 30 2009Li-Jun Guo Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis of Some New Indolizine and Pyrrolo[1,2-a]quinoline Derivatives via Nitrogen Ylides.CHEMINFORM, Issue 23 2009Nabila A. Kheder Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ,-Oxoacids Esters in the Synthesis of Benzo[f]quinoline Derivatives.CHEMINFORM, Issue 46 2007K. N. Gusak Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] A Convenient Route for the Synthesis of Pyrazolo[3,4-d]pyrimidine, Pyrazolo[3,4-b][1,6]naphthyridine and Pyrazolo[3,4-b]quinoline Derivatives.CHEMINFORM, Issue 7 2007Madhukar N. Jachak Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Cyclization of 1-Benzyl-1,2-dihydro-2-(substituted methylene)quinolines to Pyrrolo[1,2-a]quinoline Derivatives.CHEMINFORM, Issue 34 2006Reiko Fujita Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Pyrrolo(iso)quinoline Derivatives as 5-HT2C Receptor Agonists.CHEMINFORM, Issue 18 2006Howard L. Mansell Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Synthesis and Biological Activity of 5-Methylidene 1,2-Dihydrochromeno[3,4-f]quinoline Derivatives as Progesterone Receptor Modulators.CHEMINFORM, Issue 39 2003Lin Zhi Abstract For Abstract see ChemInform Abstract in Full Text. [source] New Pathway to Furo[2,3-b]quinoline Derivatives.CHEMINFORM, Issue 52 2002V. F. Traven Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: Furo[3,2-h]quinoline Derivatives as Gastric H+/K+ -ATPase Inhibitors.CHEMINFORM, Issue 36 2002Seung Kyu Kang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis and Antibacterial Activity of 1,3,4-Thia(Oxa)diazino[6,5,4-i,j]quinoline Derivatives.CHEMINFORM, Issue 17 2002E. V. Nosova Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis and Antimicrobial Activity of Novel Pyrazolo[3,4-b]quinoline Derivatives.CHEMINFORM, Issue 35 2001Ola A. El-Sayed Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] The First Proline-Catalyzed Friedlander Annulation: Regioselective Synthesis of 2-Substituted Quinoline DerivativesEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 16 2008Biao Jiang Abstract The first proline-catalyzed Friedlander annulation for the synthesis of 2-substituted 4-trifluoromethyl quinoline derivatives is described. Excellent regioselectivity as well as good yields were shown in a variety of cases, and a tandem aldol-cyclization pathway might be involved. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) [source] An Improved Protocol for the Synthesis of Quinoline-2,3-dicarboxylates under Neutral Conditions via Biomimetic ApproachHELVETICA CHIMICA ACTA, Issue 2 2010Bandaru Madhav Abstract A mild and efficient protocol for synthesis of quinoline derivatives in aqueous medium under neutral conditions is described. The reaction proceeded smoothly in H2O catalyzed by supramolecular catalyst , -CD. By this protocol, various quinoline derivatives were synthesized in excellent yields. [source] |