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QRS Voltage (qr + voltage)

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Medical Sciences100%

Selected Abstracts

Electrical and Structural Remodeling in Left Ventricular Hypertrophy,A Substrate for a Decrease in QRS Voltage?

ANNALS OF NONINVASIVE ELECTROCARDIOLOGY, Issue 3 2007
Ljuba Bacharova M.D., M.B.A., Ph.D.
Electrical remodeling in advanced stages of cardiovascular diseases creates a substrate for triggering and maintenance of arrhythmias. The electrical remodeling is a continuous process initiated already in the early stages of cardiological pathology. The aim of this opinion article was to discuss the changes in electrical properties of myocardium in left ventricular hypertrophy (LVH), with special focus on its early stage, as well as their possible reflection in the QRS amplitude of the electrocardiogram. It critically appraises the classical hypothesis related to the QRS voltage changes in LVH. The hypothesis of the relative voltage deficit is discussed in the context of supporting evidence from clinical studies, animal experiments, and simulation studies. The underlying determinants of electrical impulse propagation which may explain discrepancies between "normal" ECG findings and increased left ventricular size/mass in LVH are reviewed. [source]

Correlates of NT-proBNP concentration in patients with essential hypertension in absence of congestive heart failure

JOURNAL OF CLINICAL LABORATORY ANALYSIS, Issue 1 2010
Keizo Toda
Abstract Background: N-terminal proBNP (NT-proBNP) is widely used as a diagnostic biomarker and for the risk stratification of patients with heart failure (HF). Its role in the evaluation of patients with essential hypertension (EHT) is less clear. We examined the relationship between NT-proBNP concentrations and various clinical characteristics in hypertensive patients without HF. Methods: This study included 186 consecutive patients with EHT and no history of HF, ischemic heart disease, or atrial fibrillation. Single and multiple variable regression analyses were performed in search of clinical correlates of NT-proBNP concentrations. Results: In patients with EHT, median serum concentration of NT-proBNP was 73,pg/ml, and interquartile range (IQR) was 40,128,pg/ml. NT-proBNP was significantly higher (P<0.001) in women (87,pg/ml; IQR 55,137,pg/ml) than in men (52,pg/ml; IQR 24,115,pg/ml). Age (r=0.371, P<0.001), precordial QRS voltage (r=0.223, P<0.001), hemoglobin (Hgb) concentration, (r=,0.208, P=0.023) and estimated glomerular filtration rate (r=,0.139, P=0.044) were correlated with log-transformed NT-proBNP by multiple variable analysis. In men, age (r=0.453, P<0.001) and QRS voltage (r=0.283, P=0.004), and in women age (r=0.299, P=0.006), QRS voltage (r=0.212, P=0.019), Hgb (r=,0.182, P=0.049), and estimated glomerular filtration rate (r=,0.272, P=0.009) were correlated with serum concentrations of NT-proBNP. Conclusions: Age, gender, Hgb, left ventricular hypertrophy and renal function were correlated with NT-proBNP in patients with EHT. J. Clin. Lab. Anal. 24:12,16, 2010. © 2010 Wiley-Liss, Inc. [source]

Cardiac amyloidosis in a patient with multiple myeloma: A case report and review of literature

JOURNAL OF CLINICAL ULTRASOUND, Issue 3 2009
David Sedaghat MD
Abstract We report a case of a 52-year-old man with multiple myeloma and rapidly progressive heart failure who died unexpectedly from a probable arrhythmia. Postmortem examination revealed infiltrative amyloid cardiomyopathy, a rare cause of predominantly diastolic myocardial disease. Cardiac amyloidosis should be considered in any patient presenting with congestive heart failure, preserved systolic function, and a discrepancy between a low QRS voltage on electrocardiography and an apparent left ventricular hypertrophy on sonogram. The pattern of left ventricular diastolic dysfunction changes during the course of amyloidosis and the classically described restrictive physiology occurs only in advanced stages of the disease. © 2009 Wiley Periodicals, Inc. J Clin Ultrasound, 2009 [source]