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Attack
Kinds of Attack Terms modified by Attack Selected AbstractsHEALING LOSS, AMBIGUITY, AND TRAUMA: A COMMUNITY-BASED INTERVENTION WITH FAMILIES OF UNION WORKERS MISSING AFTER THE 9/11 ATTACK IN NEW YORK CITYJOURNAL OF MARITAL AND FAMILY THERAPY, Issue 4 2003Pauline Boss A team of therapists from Minnesota and New York workied with labor union families of workers gone missing on September 11, 2001, after the attack on the World Trade Center, where they were employed. The clinical team shares what they did, what was learned, the questions raised, and preliminary evaulations about the multiple family meeting that were the major intervention. Because of the vast diversity, training of therapists and interventions for families aimed for cultural competence. The community-based approach, preferred by union families, plus family therapy using the lens of ambiguous loss are proposed as necessary additions to disaster work. [source] NON-LETHAL SHARK ATTACK ON A BOTTLENOSE DOLPHIN (TURSIOPS SP.) CALFMARINE MAMMAL SCIENCE, Issue 1 2006Quincy Anne Gibson First page of article [source] [Commentary] TERRORIST ATTACKS AND SUBSTANCE ABUSEADDICTION, Issue 6 2009HAROLD A. POLLACK No abstract is available for this article. [source] KILLER WHALE ATTACKS ON MINKE WHALES: PREY CAPTURE AND ANTIPREDATOR TACTICSMARINE MAMMAL SCIENCE, Issue 4 2005John K. B. Ford Abstract We describe nine incidents of predation or attempted predation of minke whales (Balaenoptera acutorostrata) by mammal-hunting "transient" killer whales (Orcinus orca) in coastal waters of British Columbia, Washington, and southeastern Alaska. Pursuits of minke whales were characterized by prolonged chases on a straight heading at velocities of 15,30 km/h. In four of the nine cases the adultsized minke whale gradually outdistanced the killer whales, which abandoned the high-speed pursuit after 0.5,1 h. In one case the minke beached itself and died. Four attacks were successful. In one instance a subadult minke was killed in open water following a chase. In two cases the fleeing minke entered a confined bay and was killed by the killer whales. One adult minke was taken after apparently attempting to seek cover beside a large sailboat. Minke whales made no attempt to physically defend themselves and were killed by repeated ramming or by asphyxiation. Although killer whales are capable of sprinting speeds greater than those of minke whales, it appears that adult minkes can maintain higher sustained speeds and evade capture if sufficient space for an extended escape trajectory is available. Successful predation of minke whales in coastal waters is rare compared to pinnipeds and small cetaceans, the main prey of transient killer whales. [source] National Study on Emergency Department Visits for Transient Ischemic Attack, 1992,2001ACADEMIC EMERGENCY MEDICINE, Issue 6 2006Jonathan A. Edlow MD Abstract Objectives: To describe the epidemiology of U.S. emergency department (ED) visits for transient ischemic attack (TIA) and to measure rates of antiplatelet medication use, neuroimaging, and hospitalization during a ten-year time period. Methods: The authors obtained data from the 1992,2001 National Hospital Ambulatory Medical Care Survey. TIA cases were identified by having ICD-9 code 435. Results: From 1992 to 2001, there were 769 cases, representing 2,969,000 ED visits for TIA. The population rate of 1.1 ED visits per 1,000 U.S. population (95% CI = 0.92 to 1.30) was stable over time. TIA was diagnosed in 0.3% of all ED visits. Physicians administered aspirin and other antiplatelet agents to a small percentage of patients, and 42% of TIA patients (95% CI = 29% to 55%) received no medications at all in the ED. Too few data points existed to measure a statistically valid trend over time. Physicians performed computed tomography scanning in 56% (95% CI = 45% to 66%) of cases and performed magnetic resonance imaging (MRI) in < 5% of cases, and there was a trend toward increased imaging over time. Admission rates did not increase during the ten-year period, with 54% (95% CI = 42% to 67%) admitted. Regional differences were noted, however, with the highest admission rate found in the Northeast (68%). Conclusions: Between 1992 and 2001, the population rate of ED visits for TIA was stable, as were admission rates (54%). Antiplatelet medications appear to be underutilized and to be discordant with published guidelines. Neuroimaging increased significantly. These findings may reflect the limited evidence base for the guidelines, educational deficits, or other barriers to guideline implementation. [source] Host range of Asobara japonica (Hymenoptera: Braconidae), a larval parasitoid of drosophilid fliesENTOMOLOGICAL SCIENCE, Issue 1 2008Shinsuke IDEO Abstract We studied the host range of Asobara japonica, a larval-pupal parasitoid of drosophilid flies. Habitat selection was found to be an important determinant of host range in this parasitoid; it attacked drosophilid larvae breeding on banana and mushrooms, but seldom attacked those breeding on decayed leaves. This parasitoid was able to use diverse drosophilid taxa as hosts. Attack by A. japonica sometimes killed hosts at the larval stage, and therefore parasitoid larvae also died. Drosophila elegans and D. busckii suffered particularly high larval mortality due to the attack by A. japonica (in the latter species only when young larvae were attacked). Many individuals of D. subpulchrella also died at the pupal stage without producing parasitoids when they were parasitized at the late larval stage. In contrast, D. bipectinata, D. ficusphila, D. immigrans, D. formosana and D. albomicans were resistant to attack: large proportions of the larvae of these drosophilid species grew to adulthood, even in the presence of parasitoids. On the basis of phylogenetic information, we concluded that phylogenetic position has only limited importance as a factor determining whether a species is suitable as a host for A. japonica, at least within the genus Drosophila. [source] Ring Closure of Alkoxycarbonyl(tetracarbonyl)pyruvoyliron Complexes into Metallalactones Induced by Nucleophilic Attack of CarbanionsEUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 7 2006Patrice Cabon Abstract The reaction of carbanions with the pyruvoyl-substituted iron complex [(CO)4Fe(CO2CH3){C(O)C(O)CH3}] (1) affords the anionic trifunctionalized metallalactones [(CO)3Fe{C(O)C(CH3)(CRR,R,)OC4(O)(Fe,C4)}(CO2CH3)], (3), whose formation results from the addition of the nucleophile to the , carbonyl of the pyruvoyl moiety, followed by attack of the oxygen of this , carbonyl on a terminal carbonyl ligand. These anionic lactones react, at low temperature, with HCl to give rise to the neutral lactones [(CO)4Fe{C(O)C(CH3)(CRR,R,)OC4(O)(Fe,C4)}] (2), which were previously obtained by addition of NuH nucleophiles to 1. Complex 3(3), whose lactonic ring formation has been performed using the diethyl malonate anion (R = R, = CO2C2H5; R, = H), and the dimethyl-substituted neutral lactone 2(1) (R = R, = R, = H) have been characterized by X-ray diffraction studies. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006) [source] Attack and defence in the gastric epithelium , a delicate balanceEXPERIMENTAL PHYSIOLOGY, Issue 4 2007Rod Dimaline The gastric epithelium is a complex structure formed into tubular branched gastric glands. The glands contain a wide variety of cell types concerned with the secretion of hydrochloric acid, proteases, mucus and a range of signalling molecules. All cell types originate from stem cells in the neck region of the gland, before migrating and differentiating to assume their characteristic positions and functions. Endocrine and local paracrine mediators are of crucial importance for maintaining structural and functional integrity of the epithelium, in the face of a hostile luminal environment. The first such mediator to be recognized, the hormone gastrin, was identified over a century ago and is now established as the major physiological stimulant of gastric acid secretion. Recent studies, including those using mice that overexpress or lack the gastrin gene, suggest a number of previously unrecognized roles for this hormone in the regulation of cellular proliferation, migration and differentiation. This review focuses on the identification of hitherto unsuspected gastrin-regulated genes and discusses the paracrine cascades that contribute to the maintenance of gastric epithelial architecture and secretory function. Helicobacter infection is also considered in cases where it shares targets and signalling mechanisms with gastrin. [source] Interspecific interference and the functional response of four species of carnivorous stonefliesFRESHWATER BIOLOGY, Issue 9 2003J.M. Elliott Summary 1.,A previous study compared the functional responses to their prey and intraspecific interference in mature larvae of Perlodes microcephalus, Isoperla grammatica, Dinocras cephalotes and Perla bipunctata. The present study extends this work by assessing interspecific interference between pairs of these species in equal numbers (one, two or three larvae per species) to provide total predator densities of two, four or six larvae. Baetis larvae as prey were replaced as they were eaten, and their density per predator was varied between 20 and 200 larvae. 2.,The number of prey eaten by each competing species increased curvilinearly with prey density, the relationship being well described by a Type II model. Of the two constants in the model, handling time varied considerably between species, mean values being shortest for Perlodes, slightly higher for Isoperla, and much higher for Dinocras and Perla. It was not affected significantly either by predator density or the identity of the competing species. 3.,Attack rate also varied between species and decreased with predator density. This decrease was slight for Perlodes, and also for Dinocras and Perla in competition with Isoperla. The decrease in Dinocras and Perla was similar to that for intraspecific interference. 4.,The decrease in attack rate was described by a convex curve for Perlodes with the other three species and for Dinocras/Perla with Isoperla, but by a concave curve (negative power function) for Isoperla competing with the other three species, and for both Dinocras and Perla in competition with Perlodes. Prey consumption also decreased with predator density, the severity of competition with different species reflecting that for attack rate. 5.,A comparison with previous results for intraspecific interference showed that the latter was dominant for Perlodes in all contests and for Dinocras or Perla competing with Isoperla, whilst interspecific interference dominated for Isoperla in all contests and for Dinocras and Perla competing with Perlodes. Both types of interference were applicable to competition between Dinocras and Perla. Isoperla was the least, and Perlodes the most, aggressive of the four species with Dinocras and Perla intermediate. [source] The causes and consequences of maxillofacial injuries in elderly peopleGERODONTOLOGY, Issue 1 2002K. Rehman Abstract Objective: The occurrence of trauma in older people is well-documented; however the incidence of maxillofacial trauma is scarcely reported. Therefore, the objective of this study is to determine the causes and consequences of maxillofacial trauma in older people. Design: A five-year (March 95 - March 2000) retrospective study was earned out of all patients over the age of 65 years with facial trauma presenting to Accident and Emergency Department (A&E). The information was collected using the medical notes and discharge summaries. Setting: The Departments of A&E and Maxillofacial Surgery. Subjects: A total of 42 patients' records were examined for study related data. Results: A total of 42 patients were seen during the study period. Thirty-six gave a history of a fall, of which 15 had tripped, 5 had slipped, 3 resulted from a Transient Ischaemic Attack (TIA), 1 as a result of alcohol abuse, in 1 a prosthetic knee gave way and 11 gave no cause for the fall. Of the remaining 6 patients. 5 were assaulted and 1 had a wardrobe fall on top of him. The majority of the falls occurred during the winter months. Maxillofacial injuries were noted in 27 of the 42 patients. Sixteen patients had cheekbone fractures, 8 mandibular fractures, 2 midface and 1 orbital complex fracture. Twenty-five percent of cheekbone fractures and 50% of mandibular fractures were treated surgically. Medical history was noted in 27 patients. Conclusions: This study clearly demonstrates the majority of the facial trauma in the older people can be treated conservatively unless the patients complain of functional problems. [source] Gastric Stasis in Migraine: More Than Just a Paroxysmal Abnormality During a Migraine AttackHEADACHE, Issue 1 2006Objective.,The aim of this article is to evaluate gastric motility and emptying in the ictal and interictal period in migraine. Background.,Nausea is a predominant symptom of migraine and the basis of it is thought to be gastric stasis. Objective methods to establish this are however lacking. We utilized gastric scintigraphy studies to determine gastric motility in the ictal and interictal period of migraine. Methods.,Ten migraine subjects were compared to equal number of age and sex matched controls. Gastric scintigraphy using a standard meal was performed in all control subjects once and in all 10 migraine subjects in the interictal period and nine studies were performed in the ictal period migraine. Results.,The time to half emptying was delayed in migraine ictally (78%) and interictal period (80%) using normative data at this institution. Gastric stasis was less pronounced ictally (149.9 minutes) compared to interictal period (188.8 minutes). There was a significant delay compared to nonmigrainous controls (migraine 188.8 minutes vs normal controls 111.8 minutes; P < .05). These data were replicated in percentage of radioactive material remaining in the stomach at 2 hours. Conclusions.,Contrary to previous belief, this study has demonstrated that migraineurs suffer from gastric stasis both during and outside an acute migraine attack. This may suggest that migraineurs may have an abnormal autonomic function compared to nonmigrainous controls. The potential role of this in pathophysiology of migraine is discussed and avenues for further investigations are explored. [source] Feminism in the Grips of a Pincer Attack,Traditionalism, liberalism, and globalismINTERNATIONAL JOURNAL OF JAPANESE SOCIOLOGY, Issue 1 2005Yumiko Ehara Abstract:, The dichotomy of individualism versus collectivism is one of the pivots around which political ideologies in postwar Japanese society can be broken down. Many people had thought that what postwar Japan needed was the development of modern individuals who represented a departure from feudalistic thinking. Against the backdrop of uncertainties related to employment and life in general engendered by a prolonged economic stagnation and globalism, Japanese society in the twenty-first century is being pounded by a tempest of neoliberalism and neoconservatism. In the midst of this storm, ideas advocating social policies that promote gender equality are being dismantled by both of these forces. This is because the power of traditionalism as a force for asserting a revisionist ideology in modern Japanese society primarily constitutes the power of neoconservatism, which embraces neoliberalism with a view to revitalizing the free economy through the elimination of social welfare and the intensification of free competition. In order to establish formidable economic competitiveness, neoliberalism and neoconservatism (neoliberalism = neoconservatism) reject domestic systems geared towards labor protection (deregulation) and extol familism and nationalism as means to bringing social unrest under control through the mobilization of the labor force (traditionalism). However, the habitual way of thinking that places traditionalism and liberalism in a dichotomous pivot remains ingrained within us even now. Because globalization reinforces social mobility, these two positions will continue to gain strength even as they conflict with each other. With feminism in the grips of a pincer attack, the movement will struggle to maintain its breath. [source] Attack or consumption of Epomophorus (Chiroptera) by Paraxerus (Rodentia) and Papio (Primates) in TanzaniaAFRICAN JOURNAL OF ECOLOGY, Issue 4 2009William T. Stanley No abstract is available for this article. [source] New Yorkers Respond to the World Trade Center Attack: An Anatomy of an Emergent Volunteer OrganizationJOURNAL OF CONTINGENCIES AND CRISIS MANAGEMENT, Issue 1 2008William R. Voorhees In the aftermath of the New York World Trade Center attack, an emergent group of citizen volunteers organized to provide needed supplies to the workers at Ground Zero. The emergent-group phenomenon has been documented after many disasters. This paper examines the organization of this emergent group through the organizational characteristics of structure, legitimacy, communications, leadership and organizational change. Finally, it argues that through a better understanding of the organizational characteristics, emergency-management personnel will be better prepared to manage and coordinate the activities of disaster-related emergent groups. [source] A remarkable difference in the deprotonation steps of the Friedel,Crafts acylation and alkylation reactionsJOURNAL OF PHYSICAL ORGANIC CHEMISTRY, Issue 11 2009Shinichi Yamabe Abstract Friedel,Crafts acylation and alkylation reactions were investigated using density functional theory calculations. The reaction systems studied were (benzene,+,acetyl chloride,+,Al2Cl6 (or AlCl3)) and (benzene,+,2-chloropropane,+,Al2Cl6). In the acylation reaction, the acylium ion intermediate is reached either via a MeC(Cl)OAl2Cl6 complex or via direct Cl transfer: MeC(O)ClAl2Cl6,,,MeCO,+Al2Cl. The ion adds to benzene electrophilically to form a Wheland intermediate containing a strong CHCl hydrogen bond, which leads to deprotonation and the subsequent formation of acetophenone. The resulting HClAl2Cl6 fragment is subjected to a nucleophilic attack by the carbonyl oxygen of the acetophenone, and recovery of the Al2Cl6 bridge is unlikely. Attack of the Al2Cl6 moiety by MeC(Cl)O gives the complex MeC(Cl)O,AlCl3, whose reactivity toward acylation is similar to that of the MeC(Cl)O,Al2Cl6 complex. In the alkylation reaction, deprotonation does not take place, but rather a [1,2] H-shift from the Wheland intermediate. The resulting , -protonated cumene undergoes deprotonation, with subsequent recovery of the Al2Cl6 bridge. In addition, the Al2Cl6 -catalyzed isomerization of the n -propyl to the isopropyl cation was found to be a dyotropic shift. Copyright © 2009 John Wiley & Sons, Ltd. [source] Attack of the artillery fungus on vinyl sidingJOURNAL OF VINYL & ADDITIVE TECHNOLOGY, Issue 2 2005Richard F. Grossman The artillery fungus, Sphaerobolus stellatus, ejects dark-colored spores for a distance of several meters. These are enclosed in an adhesive layer comprised of carotenoid pigments. On exposure to sunlight, the pigment layer resinifies and develops a strong bond to vinyl siding capstock. The damage is compounded when the homeowner removes the bonded spores abrasively, destroying the protective capstock layer. Strategies to protect vinyl siding or to defeat the microorganism are discussed. J. VINYL. ADDIT. TECHNOL., 11:63,64, 2005. © 2005 Society of Plastics Engineers [source] Demographic Data on the Victims of the September 11, 2001 Terror Attack on the World Trade Center, New York CityPOPULATION AND DEVELOPMENT REVIEW, Issue 3 2002Article first published online: 27 JAN 200 The magnitude of the death toll resulting from the attack on the World Trade Center is without precedent in the history of terrorist acts. Because of the scale and destructiveness of the buildings' collapse, a final list of the victims required a lengthy process, more so than was the case at the other sites of terrorist violence on the same day,at the Pentagon, Virginia (193 killed, 68 of these on American Airlines Flight 77), and near Shanksville, Pennsylvania (45 killed in the crash of United Airlines Flight 93). After the passing of a year, the list of the victims in New York, while essentially complete, is still not officially closed. On August 19, 2002, the city's medical examiner's office issued a list containing 2,819 names. Reproduced below are some data, released by the city's office of vital statistics, on the demographic characteristics of 2,723 victims (59 of these on United Airlines Flight 175 and 89 on American Airlines Flight 11) for whom a death certificate had been issued,an exacting procedure,as of August 16,2002. The cause of death, in each instance, was entered as homicide. The age distribution reflects the character of the World Trade Center,a workplace,and the time of day,early for tourist visits. The youngest victims perished as passengers in the two airplanes flown into the twin towers. [source] Activation of the prefrontal cortex to trauma-related stimuli measured by near-infrared spectroscopy in posttraumatic stress disorder due to terrorismPSYCHOPHYSIOLOGY, Issue 4 2003Koji Matsuo Abstract To develop a noninvasive method for psychophysiological assessment of posttraumatic stress disorder (PTSD), 34 victims of the Tokyo Subway Sarin Attack in 1995 including 8 diagnosed as PTSD and 12 controls were examined by a multichannel near-infrared spectroscopy (NIRS) system. Hemodynamic response in the prefrontal cortex was monitored during the presentation of trauma-related and control stimuli by video images. Skin conductance response (SCR) was also examined. Oxygenated hemoglobin significantly increased during the trauma-related image in the victims with or without PTSD. Deoxygenated hemoglobin significantly decreased only in victims with PTSD. No significant alteration was found in controls. Significantly enhanced SCR was also observed in the victims with PTSD during trauma-related stimuli. The findings suggest that measurement of cerebral hemodynamic response by NIRS is useful for psychophysiological assessment of PTSD. [source] Attack,norm separation for detecting attack-induced quality problems on computers and networksQUALITY AND RELIABILITY ENGINEERING INTERNATIONAL, Issue 5 2007Nong Ye Abstract Cyber attacks on computer and network systems induce system quality and reliability problems, and present a significant threat to the computer and network systems that we are heavily dependent on. Cyber attack detection involves monitoring system data and detecting the attack-induced quality and reliability problems of computer and network systems caused by cyber attacks. Usually there are ongoing normal user activities on computer and network systems when an attack occurs. As a result, the observed system data may be a mixture of attack data and normal use data (norm data). We have established a novel attack,norm separation approach to cyber attack detection that includes norm data cancelation to improve the data quality as an important part of this approach. Aiming at demonstrating the importance of norm data cancelation, this paper presents a set of data modeling and analysis techniques developed to perform norm data cancelation before applying an existing technique of anomaly detection, the chi-square distance monitoring (CSDM), to residual data obtained after norm data cancelation for cyber attack detection. Specifically, a Markov chain model of norm data and an artificial neural network (ANN) of norm data cancelation are developed and tested. This set of techniques is compared with using CSDM alone for cyber attack detection. The results show a significant improvement of detection performance by CSDM with norm data cancelation over CSDM alone. Copyright © 2006 John Wiley & Sons, Ltd. [source] Common Sense Rediscovered: Lessons from the Terrorist Attack on America by Dale M. HerderTHE JOURNAL OF AMERICAN CULTURE, Issue 3 2006Ray B. Browne No abstract is available for this article. [source] Ancient Weapons for Attack and Defense: the Pore-forming Polypeptides of Pathogenic Enteric and Free-living Amoeboid Protozoa,THE JOURNAL OF EUKARYOTIC MICROBIOLOGY, Issue 5 2004MATTHIAS LEIPPE ABSTRACT Pore-forming polypeptides have been purified from several amoeboid protozoans that are well-known human pathogens. Obligate enteric parasites, such as Entamoeba histolytica, and free-living but potentially highly pathogenic species, such as Naegleria fowleri, contain these cytolytic molecules inside cytoplasmic granules. Comprehensive functional and structural studies have been conducted that include isolation of the proteins from their natural sources, monitoring of their biological activity towards different targets, and molecular cloning of the genes of their precursors. In the case of the most prominent member of the protein family, with respect to protozoans, the three-dimensional structure of amoebapore A was solved recently. The amoebic pore-forming polypeptides can rapidly perforate human cells. The antibacterial activity of amoebapores and of related polypetides from free-living protozoa points to a more vital function of these molecules: inside the digestive vacuoles they combat growth of phagocytosed bacteria which are killed when their cytoplasmic membranes are permeabilized. The concommitant activity of these proteins towards host cells may be due to a coincidental selection for an efficient effector molecule. Nonetheless, several lines of evidence indicate that these factors are involved in pathogenesis of fatal diseases induced by amoeboid protozoa. [source] In the Wake of Terrorist Attack, Hatred May Mask FearANALYSES OF SOCIAL ISSUES & PUBLIC POLICY, Issue 1 2002Jennifer J. Freyd Reactions of anger, rage, and hatred in the wake of September 11 terrorist attack are considered in light of the psychology of emotion and stress. Acknowledging underlying grief and fear through self-reflection, writing, and social communication is likely to reduce unchecked anger, rage, and hatred. Hate crimes may also have some psychological bases in responses to stress called "flight-or-fight." When flight is not an option, identifying and hating an enemy may have had evolutionary value for survival. This response creates harm in the current situation. An alternative cooperative response to stress, called "tend-and-befriend" by researchers, will be more helpful. [source] Fast food and neighborhood stroke risk,ANNALS OF NEUROLOGY, Issue 2 2009Lewis B. Morgenstern MD Objective To investigate the association between the number of fast food restaurants and ischemic stroke in neighborhoods. Methods This work was a prespecified part of the Brain Attack in Corpus Christi (BASIC) project. Ischemic stroke cases were prospectively ascertained in Nueces County, Texas. Home addresses were geocoded and used to establish the census tract for each stroke case. Census tracts were used as proxies for neighborhoods (n = 64). Using a standard definition, fast food restaurants were identified from a commercial list. Poisson regression was used to study the association between the number of fast food restaurants in the neighborhood, using a 1-mile buffer around each census tract, and the risk of stroke in the neighborhood. Models were adjusted for demographics and neighborhood socioeconomic status (SES). Results There were 1,247 completed ischemic strokes from January 2000 through June 2003 and 262 fast food restaurants. The median number of fast food restaurants per census tract including buffer was 22 (interquartile range, 12,33). Adjusting for neighborhood demographics and SES, the association of fast food restaurants with stroke was significant (p = 0.02). The association suggested that the risk of stroke in a neighborhood increased by 1% for every fast food restaurant (relative risk, 1.01; 95% confidence interval [CI], 1.00,1.01). The relative risk of stroke comparing neighborhoods in the 75th to the 25th percentile of the distribution of fast food restaurants was 1.13 (95% CI, 1.02,1.25). Interpretation Controlling for demographic and SES factors, there was a significant association between fast food restaurants and stroke risk in neighborhoods in this community-based study. Ann Neurol 2009;66:165,170 [source] ChemInform Abstract: Lewis Acid Catalyzed Indole Synthesis via Intramolecular Nucleophilic Attack of Phenyldiazoacetates to Iminium Ions.CHEMINFORM, Issue 18 2010Lei Zhou Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Hospital and Demographic Influences on the Disposition of Transient Ischemic AttackACADEMIC EMERGENCY MEDICINE, Issue 2 2008Jeffrey H. Coben MD Abstract Objectives:, There is substantial variation in the emergency department (ED) disposition of patients with transient ischemic attack (TIA), and the factors responsible for this variation have not been determined. In this study, the authors examined the influence of clinical, sociodemographic, and hospital characteristics on ED disposition. Methods:, All ED-treated TIA cases from community hospitals in 11 states were identified from the 2002 Healthcare Cost and Utilization Project (HCUP). Using the aggregate data, descriptive analyses compared admitted and discharged cases. Pearson's chi-square test was used to determine the statistical significance of these comparisons. Based on the results of the bivariate analyses, logistic regression models of the likelihood of hospital admission were derived, using a stepwise selection process. Adjusted risk ratios and 95% confidence intervals (CI) were calculated from the logistic regression models. Results:, A total of 34,843 cases were identified in the 11 states, with 53% of cases admitted to the hospital. In logistic regression models, differences in admission status were found to be strongly associated with clinical characteristics such as age and comorbidities. After controlling for comorbidities, differences in admission status were also found to be associated to hospital type and with sociodemographic characteristics, including county of residence and insurance status. Conclusions:, While clinical factors predictably and appropriately impact the ED disposition of patients diagnosed with TIA, several nonclinical factors are also associated with differences in disposition. Additional research is needed to better understand the basis for these disparities and their potential impact on patient outcomes. [source] Electrophilic Attack on Sulfur,Sulfur Bonds.CHEMINFORM, Issue 43 2004Part 1. Abstract For Abstract see ChemInform Abstract in Full Text. [source] Nucleophilic Additions to Fused Bicyclic Five-Membered Ring Oxocarbenium Ions: Evidence for Preferential Attack on the Inside Face.CHEMINFORM, Issue 11 2004Deborah M. Smith Abstract For Abstract see ChemInform Abstract in Full Text. [source] Electrophilic Attack on Sulfur,Sulfur Bonds: Coordination of Lithium Cations to Sulfur-Rich Molecules Studied by Ab Initio MO MethodsCHEMISTRY - A EUROPEAN JOURNAL, Issue 4 2005Yana Steudel Dr. Abstract Complex formation between gaseous Li+ ions and sulfur-containing neutral ligands, such as H2S, Me2Sn (n = 1,5; Me = CH3) and various isomers of hexasulfur (S6), has been studied by ab initio MO calculations at the G3X(MP2) level of theory. Generally, the formation of LiSn heterocycles and clusters is preferred in these reactions. The binding energies of the cation in the 29 complexes investigated range from ,88 kJ,mol,1 for [H2SLi]+ to ,189 kJ,mol,1 for the most stable isomer of [Me2S5Li]+ which contains three-coordinate Li+. Of the various S6 ligands (chair, boat, prism, branched ring, and triplet chain structures), two isomeric complexes containing the S5S ligand have the highest binding energies (,163±1 kJ,mol,1). However, the global minimum structure of [LiS6]+ is of C3v symmetry with the six-membered S6 homocycle in the well-known chair conformation and three LiS bonds with a length of 256 pm (binding energy: ,134 kJ,mol,1). Relatively unstable isomers of S6 are stabilized by complex formation with Li+. The interaction between the cation and the S6 ligands is mainly attributed to ion,dipole attraction with a little charge transfer, except in cations containing the six sulfur atoms in the form of separated neutral S2, S3, or S4 units, as in [Li(S3)2]+ and [Li(S2)(S4)]+. In the two most stable isomers of the [LiS6]+ complexes, the number of SS bonds is at maximum and the coordination number of Li+ is either 3 or 4. A topological analysis of all investigated complexes revealed that the LiS bonds of lengths below 280 pm are characterized by a maximum electron-density path and closed-shell interaction. [source] Comparative Analysis of Indoor Levels of Suspended Particulates and Nitrogen Dioxide a Few Hours later after an Asthmatic AttackCHINESE JOURNAL OF CHEMISTRY, Issue 11 2007Emmanuel Ehiabhi UKPEBOR Abstract Suspended particulates (TSP) and nitrogen dioxide (NO2) are known respiratory irritants linked to asthma aggravation. This pilot study was designed to investigate the role of these pollutants on the frequency of asthmatic attack on two of the inhabitants of a household. The surveillance of TSP and NO2 in this household commenced a few hours later, after one of the occupants suffered an attack. The TSP load determination was done using a High Volume Gravimetric sampler and a light scattering method via a Haz-Dust 10 µm particulate monitor. Palmes Diffusion tubes for NO2 and a portable Crowcon Gasman toxic gas detector were utilized for NO2 screening. In the first day of monitoring in the living room, the in situ particulate sampler (Haz-Dust) recorded a mean TSP level of 26,000 µg·m,3. A confirmatory test with the eight hour average Gravimetric sampler gave 25,833 µg·m,3. With the use of the Gasman toxic gas detector for NO2, the NO2 concentration for the first few hours of sampling was lower than 188 µg·m,3, the detection limit of this instrument. However, the exact NO2 concentrations for the 7 day monitoring after the attack were 27.50 µg·m,3 (kitchen) and 12.03 µg·m,3 (living room) as recorded by the Palmes diffusion tubes. [source] Characteristics of Migraine Attacks and Responses to Almotriptan Treatment: A Comparison of Menstrually Related and Nonmenstrually Related MigrainesHEADACHE, Issue 2 2008Merle L. Diamond MD Objectives., To compare the clinical characteristics of menstrually related migraines (MRMs) and nonmenstrually related migraines (nonMRMs) and to investigate the efficacy of almotriptan in the treatment of these migraine subtypes. Design/Methods., These are post hoc analyses of data from the AXERT® Early miGraine Intervention Study (AEGIS), a multicenter, double-blind, parallel-group trial that evaluated adults with IHS-defined migraine with and without aura. Patients were randomized 1 : 1 to treat 3 consecutive headaches with almotriptan 12.5 mg or matching placebo at the first sign of headache typical of their usual migraine, at any level of pain intensity but within 1 hour of onset. MRMs were defined as those occurring ±2 days of the first day of menstrual flow. Post hoc analyses to describe headache characteristics pooled all migraine attacks experienced by patients who reported ,1 menses during the study regardless of assigned treatment group. The post hoc efficacy analyses included outcomes of almotriptan treatment compared with placebo treatment for all migraines in patients with a menstrual record. Results., Of the 275 women in the AEGIS intent-to-treat population, 190 (69.1%; 97 almotriptan, 93 placebo; aged 18-54 years) reported ,1 menses during the trial. Of the 506 migraines reported by these patients, 95 (18.8%) occurred ±2 days of the first day of menstrual flow and were defined as MRM. Aura was associated with 11.7% of MRM and 15.0% of nonMRM. Allodynia-associated symptoms were present with 62.8% of MRM and 57.0% of nonMRM. Prior to treatment, 19.1% of MRM were associated with normal functional ability, 68.1% with disturbed functional ability, and 12.8% required bed rest compared with 18.9%, 68.8%, and 12.3%, respectively, of nonMRM. Pretreatment pain intensity was mild in 40.0%, moderate in 47.4%, and severe in 12.6% of MRM compared with 43.6%, 47.2%, and 9.2%, respectively, of nonMRM. Almotriptan treatment efficacy outcomes for MRM vs nonMRM, respectively, were: 2-hour pain relief, 77.4% vs 68.3%; 2-hour pain free, 35.4% vs 35.9%; and sustained pain free, 22.9% vs 23.8%. Almotriptan was similarly effective in relieving migraine-associated symptoms and improving functional disability associated with both MRM and nonMRM. Conclusions., Prior to treatment, the presence of migraine-associated characteristics including aura, allodynia-associated symptoms, photophobia, phonophobia, and nausea were similar for both MRM and nonMRM attacks. The pretreatment levels of pain intensity and functional disability were likewise similar across the migraine subtypes. Almotriptan was equally effective in the treatment of both MRM and nonMRM attacks and was associated with an adverse event profile that was similar to placebo treatment. [source] | ||||||||||||||||||||||||||||||||||||||||||||||||||||