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Proportionality
Kinds of Proportionality Selected AbstractsDETERRENCE: CREDIBILITY AND PROPORTIONALITYECONOMICS & POLITICS, Issue 3 2009DANIEL G. ARCE This paper extends the analysis of deterrence to examine terrorism, nuclear proliferation, and rogue nations. Such situations are characterized by differential pre-emptive and response capacity, in contrast to the traditional deterrence literature on nuclear superpowers, where such factors are absent. We focus on the credibility of deterrence responses to pre-emption and show that credible (subgame-perfect) responses are rarely proportional. The analysis is also extended to asymmetric deterrence scenarios whereby credibility and proportionality depend on the potential aggressor's access to conflict technology and the responder's preferences for indirect conflict vs. the status quo. [source] Proportionality in the Morality of WarPHILOSOPHY AND PUBLIC AFFAIRS, Issue 1 2005THOMAS HURKA First page of article [source] How Well do Sentencing Guidelines Work?: Equity, Proportionality and Consistency in the Determination of Fine Levels in the Magistrates' Courts of England and WalesTHE HOWARD JOURNAL OF CRIMINAL JUSTICE, Issue 1 2009JOHN W. RAINE Abstract: This article considers the scope and potential of sentencing guidelines specifically in relation to the imposition of financial penalties by the courts. Evidence is presented from research with the judiciary in England on the challenge of ensuring equity (that is, equality of impact) in the burden of such penalties, proportionality in relation to the relative seriousness of different offences, and consistency in the pattern of fine levels between individual sentencers and in different courts. The research explored how magistrates and district judges went about deciding levels of penalty to impose in a series of structured fines sentencing exercises and highlighted some of the difficulties in developing a satisfactory methodology to achieve an acceptable balance between the three objectives of achieving equity, proportionality and consistency. Key among the research findings was the prime importance in sentencers' perceptions of ,proportionality', and accordingly the article concludes by considering the consequences of this finding for the design of guidelines on financial penalty-setting. [source] Necessity, Proportionality and the Use of Force by States, by Judith GardamTHE MODERN LAW REVIEW, Issue 4 2006Phoebe Okowa No abstract is available for this article. [source] ESI+ MS/MS confirmation of canine ivermectin toxicity,JOURNAL OF MASS SPECTROMETRY (INCORP BIOLOGICAL MASS SPECTROMETRY), Issue 1 2009A. F. Lehner Abstract Ivermectin is a semisynthetic macrocyclic lactone anthelmintic of the avermectin family derived from Streptomyces fermentation products. Avermectins are used as antiparasitic agents in domestic animals; although considered relatively safe, one must consider animal species, breed, weight, and age in dosage determinations. In January 2006, two canines were presented to the UK Livestock Disease Diagnostic Center after dying from suspected ivermectin overdoses [30,50 mg/kg body weight]. To confirm this clinical diagnosis we developed a rapid, sensitive semiquantitative ElectroSpray Ionization,Mass Spectrometry (ESI/MS) method for ivermectin in canine tissue samples. Pharmaceutical ivermectin contains two ivermectins differing by a single methyl group, and each compound forms interpretation-confounding adducts with tissue Na+ and K+ ions. We now report that ivermectin administration was clearly confirmed by comparison with standard and dosage forms of ivermectin, and simple proportionalities based on mass spectral intensity of respective molecular ions allowed semiquantitative estimates of injection site tissue concentrations of 20 and 40 µg/g tissue (wet weight) in these animals, consistent with the history of ivermectin administration and the clinical signs observed. There is a distinct need for both rapid detection and confirmation of toxic exposures in veterinary diagnostics, whether for interpretation of clinical cases antemortem or for forensic reasons postmortem. It is vital that interpreters of analytical results have appropriate guidance in the scientific literature and elsewhere so as to enable clear-cut answers. The method presented here is suitable for routine diagnostic work in that it allows rapid extraction of ivermectin from tissue samples, avoids the need for high-performance liquid chromatography and allows ready interpretation of the multiple ivermectin species seen by ESI+ MS/MS in samples originating from veterinary dosage forms. Copyright © 2008 John Wiley & Sons, Ltd. [source] Determination of nucleation parameters and the solid liquid interfacial energy of the KCl-ethanol-water systemCRYSTAL RESEARCH AND TECHNOLOGY, Issue 5 2007Waid Omar Abstract The kinetic parameters of homogeneous nucleation of KCl in different ethanol-water solvent mixtures were determined at 25°C from the experimental measurements of the width of the metastable zone at different cooling rates. The ethanol mass ratio in the ethanol water solvent mixture was varied from 0-0.9 and the metastable zone width for each solvent mixture was measured under the cooling rates of 10, 20 and 30 K/h. The influence of ethanol ratio on the activity coefficient was calculated. It was found that increasing the ethanol ratio in the solvent mixture leads to an increase in the mean molal activity coefficient. The experimental results obtained showed that the increase in the ethanol ratio in the solvent widens the metastable zone for the crystallization of KCl. Also it has inferred from the calculations based on the classical nucleation theory that increasing of the ethanol ratio in the solvent mixture resulted in an increase of the nucleation rate order, increase of the critical size of nuclei and increase of the solid liquid interfacial energy. It has been found that the solid liquid interfacial energy can be good correlated with inversely proportionality to the solubility. (© 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source] Surviving psychiatry in an era of,popular punitiveness'ACTA PSYCHIATRICA SCANDINAVICA, Issue 399 2000J. Peay In an era when sentencing of mentally disordered offenders has been progressively influenced by protective considerations, the role psychiatrists play in the sentencing process is problematic. Where an offender's legitimate expectation of proportionality in sentencing can be trumped by psychiatric assessments, not of therapeutic need, but of either predictions of risk or untreatability or both, leading to disproportionate and potentially damaging custodial sentences, then psychiatrists should recognize that they are ethically compromised. [source] Universal foliage-stem scaling across environments and species in dicot trees: plasticity, biomechanics and Corner's RulesECOLOGY LETTERS, Issue 3 2009Mark E. Olson Abstract Trees range from small-leaved, intricately branched species with slender stems to large-leaved, coarsely branched ones with thick stems. We suggest a mechanism for this pattern, known as Corner's Rules, based on universal scaling. We show similar crown area,stem diameter scaling between trunks and branches, environments, and species spanning a wide range of leaf size and stem biomechanics. If crown and stem maintain metabolically driven proportionality, but similar amounts of photosynthates are produced per unit crown area, then the greater leaf spacing in large-leaved species requires lower density stem tissue and, meeting mechanical needs, thicker stems. Congruent with this scenario, we show a negative relationship between leaf size and stem Young's modulus. Corner's Rules emerge from these mutual adjustments, which suggest that adaptive studies cannot consider any of these features independently. The constancy of scaling despite environmental challenges identifies this trait constellation as a crucial axis of plant diversification. [source] Policy options for alcohol price regulation: the importance of modelling population heterogeneityADDICTION, Issue 3 2010Petra Sylvia Meier ABSTRACT Context and aims Internationally, the repertoire of alcohol pricing policies has expanded to include targeted taxation, inflation-linked taxation, taxation based on alcohol-by-volume (ABV), minimum pricing policies (general or targeted), bans of below-cost selling and restricting price-based promotions. Policy makers clearly need to consider how options compare in reducing harms at the population level, but are also required to demonstrate proportionality of their actions, which necessitates a detailed understanding of policy effects on different population subgroups. This paper presents selected findings from a policy appraisal for the UK government and discusses the importance of accounting for population heterogeneity in such analyses. Method We have built a causal, deterministic, epidemiological model which takes account of differential preferences by population subgroups defined by age, gender and level of drinking (moderate, hazardous, harmful). We consider purchasing preferences in terms of the types and volumes of alcoholic beverages, prices paid and the balance between bars, clubs and restaurants as opposed to supermarkets and off-licenses. Results Age, sex and level of drinking fundamentally affect beverage preferences, drinking location, prices paid, price sensitivity and tendency to substitute for other beverage types. Pricing policies vary in their impact on different product types, price points and venues, thus having distinctly different effects on subgroups. Because population subgroups also have substantially different risk profiles for harms, policies are differentially effective in reducing health, crime, work-place absence and unemployment harms. Conclusion Policy appraisals must account for population heterogeneity and complexity if resulting interventions are to be well considered, proportionate, effective and cost-effective. [source] DETERRENCE: CREDIBILITY AND PROPORTIONALITYECONOMICS & POLITICS, Issue 3 2009DANIEL G. ARCE This paper extends the analysis of deterrence to examine terrorism, nuclear proliferation, and rogue nations. Such situations are characterized by differential pre-emptive and response capacity, in contrast to the traditional deterrence literature on nuclear superpowers, where such factors are absent. We focus on the credibility of deterrence responses to pre-emption and show that credible (subgame-perfect) responses are rarely proportional. The analysis is also extended to asymmetric deterrence scenarios whereby credibility and proportionality depend on the potential aggressor's access to conflict technology and the responder's preferences for indirect conflict vs. the status quo. [source] Pharmacokinetics of carisbamate (RWJ-333369) in healthy Japanese and Western subjectsEPILEPSIA, Issue 8 2009Peter Zannikos Summary Purpose:, To compare the pharmacokinetics of carisbamate (RWJ-333369) in healthy Japanese and Western adults, and to comparatively assess carisbamate safety and tolerability between the two populations. Methods:, An open-label study was conducted in 24 Japanese and 24 Caucasian healthy subjects. Subjects received a single oral dose of 250 mg carisbamate on day 1 followed by a 3-day washout period; twice-daily dosing of 250 mg carisbamate on days 5,8; subsequently, 500 mg on days 9,12 and a single dose of 500 mg on day 13. Plasma samples were collected for a pharmacokinetic analysis on days 1, 8, and 13. Plasma and urine samples were analyzed for carisbamate and its urinary metabolites by liquid-chromatography-mass-spectrometry. Results:, Following a single dose, carisbamate Cmax and area under the curve (AUC) geometric mean ratios were 16.4% and 28.8% higher in Japanese than in Caucasians, respectively; these differences were statistically significant and their 90% confidence intervals (CIs) fell outside of the 80,125% limits, which are considered not to be of clinical significance. With dose,body weight normalization, Cmax and AUC were similar in Japanese and Caucasian subjects and the 90% CIs were within the 80,125% boundaries. Carisbamate was well tolerated, and its mean oral clearance and half-life were similar in both groups, ranging from 35.1,41.4 ml/h/kg and 11.5,12.8 h. Discussion:, Carisbamate plasma exposure (AUC) and Cmax in Japanese subjects is ,20,25% higher than in Caucasians due to a higher mg/kg dose. After body weight normalization, carisbamate pharmacokinetics was similar between Japanese and Caucasian subjects following single and multiple dosing, and showed the same dose proportionality. [source] Density Functional Study of the Complexation Reaction of Sn(CH3)3X (X = F, Cl, Br and I) with Halide AnionsEUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 20 2003Frank De Proft Abstract The Lewis acid-base reaction between Sn(CH3)3X and Y, (with X, Y = F, Cl, Br and I) has been studied using quantum chemical calculations. Complexation energies were calculated at the Density Functional Theory (DFT) level and rationalized on the basis of a local application of the hard and soft acids and bases principle. It was observed that smaller differences in the local softness of the interacting sites in the Lewis acid and base correspond to stronger interactions. Moreover, the calculated sequences in complexation energies can be reproduced using equations containing chemical concepts introduced within the framework of conceptual density functional theory and rooted in the hard and soft acids and bases principle and referring only to the reactants. A method of treating the electronegativity and softness of the halide anions is presented based on a Taylor expansion of the electronegativity of the neutral halogens and the softness-polarizability proportionality. Experimental evidence for the calculated sequences was gathered from measured 117Sn chemical shifts and 1J (13C- 119/117Sn) coupling constant changes upon complexation. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003) [source] Long-term carbon exchange in a sparse, seasonally dry tussock grasslandGLOBAL CHANGE BIOLOGY, Issue 10 2004John E. Hunt Abstract Rainfall and its seasonal distribution can alter carbon dioxide (CO2) exchange and the sustainability of grassland ecosystems. Using eddy covariance, CO2 exchange between the atmosphere and a sparse grassland was measured for 2 years at Twizel, New Zealand. The years had contrasting distributions of rain and falls (446 mm followed by 933 mm; long-term mean=646 mm). The vegetation was sparse with total above-ground biomass of only 1410 g m,2. During the dry year, leaf area index peaked in spring (November) at 0.7, but it was <0.2 by early summer. The maximum daily net CO2 uptake rate was only 1.5 g C m,2 day,1, and it occurred before mid-summer in both years. On an annual basis, for the dry year, 9 g C m,2 was lost to the atmosphere. During the wet year, 41 g C m,2 was sequestered from the atmosphere. The net exchange rates were determined mostly by the timing and intensity of spring rainfall. The components of ecosystem respiration were measured using chambers. Combining scaled-up measurements with the eddy CO2 effluxes, it was estimated that 85% of ecosystem respiration emanated from the soil surface. Under well-watered conditions, 26% of the soil surface CO2 efflux came from soil microbial activity. Rates of soil microbial CO2 production and net mineral-N production were low and indicative of substrate limitation. Soil respiration declined by a factor of four as the soil water content declined from field capacity (0.21 m3 m,3) to the driest value obtained (0.04 m3 m,3). Rainfall after periods of drought resulted in large, but short-lived, respiration pulses that were curvilinearly related to the increase in root-zone water content. Coupled with the low leaf area and high root : shoot ratio, this sparse grassland had a limited capacity to sequester and store carbon. Assuming a proportionality between carbon gain and rainfall during the summer, rainfall distribution statistics suggest that the ecosystem is sustainable in the long term. [source] Cocatalysis by ruthenium(III) in hydrogen ions catalyzed oxidation of iodide ions: A kinetic studyINTERNATIONAL JOURNAL OF CHEMICAL KINETICS, Issue 10 2004Praveen K. Tandon RuCl3 further catalyzes the oxidation of iodide ion by K3Fe(CN)6, already catalyzed by hydrogen ions. The rate of reaction, when catalyzed only by hydrogen ions, was separated graphically from the rate when both Ru(III) and H+ ions catalyzed the reaction. Reactions studied separately in the presence as well as absence of RuCl3 under similar conditions were found to follow second-order kinetics with respect to [I,], while the rate showed direct proportionality with respect to [Fe(CN)6]3,, [RuCl3], and [H+]. External addition of [Fe(CN)6]4, ions retards the reaction velocity, while changing the ionic strength of the medium has no effect on the rate. With the help of the intercept of the catalyst graph, the extent of the reaction that takes place without adding Ru(III) was calculated and it was in accordance with the values obtained from the reaction in which only H+ ions catalyzed the reaction. It is proposed that ruthenium forms a complex, which slowly disproportionates into the rate-determining step. Arrhenius parameters at four different temperatures were also calculated. © 2004 Wiley Periodicals, Inc. Int J Chem Kinet 36: 545,553, 2004 [source] Exchange rates, prices and money: A long-run perspectiveINTERNATIONAL JOURNAL OF FINANCE & ECONOMICS, Issue 4 2001Paul De Grauwe Abstract In this paper we analyse the long-run proportionality and neutrality propositions between inflation and money growth and between exchange rate changes and money growth. Using a sample of 100 countries over a thirty-year period we find that the evidence in favour of these propositions is weak for the low inflation countries and very strong for the high inflation countries. We propose an explanation based on productivity shocks and transaction costs. Copyright © 2001 John Wiley & Sons, Ltd. [source] Characterizations of consistent pairwise comparison matrices over abelian linearly ordered groupsINTERNATIONAL JOURNAL OF INTELLIGENT SYSTEMS, Issue 10 2010Bice Cavallo We consider the framework of pairwise comparison matrices over abelian linearly ordered groups. We introduce the notion of ,-proportionality that allows us to provide new characterizations of the consistency, efficient algorithms for checking the consistency and for building a consistent matrix. Moreover, we provide a new consistency index. © 2010 Wiley Periodicals, Inc. [source] Computation on symmetry-invariant basesINTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY, Issue 1 2003Jian Wu Abstract There is standard methodology available to facilitate electronic structure computations on a space that is invariant under a symmetry group. Here, we focus on additional consequences that arise if the basis itself is invariant under the symmetry group (i.e., in the case that application of symmetry operations to each basis vector yields, up to proportionality, a single basis vector). In illustration of the formal development, examples are considered where the symmetries are point-group symmetries and the basis vectors are Slater determinants over singly occupied atomic orbitals, as for an open-shell valence bond (VB) model. Several other types of examples are mentioned, e.g., a basis of chemically motivated resonance structures, as for a VB model, or an orbital basis of atomic orbitals for a one-electron Hückel-type model. © 2003 Wiley Periodicals, Inc. Int J Quantum Chem 94: 7,22, 2003 [source] Experimental Analysis of Grazing by the Mayfly Meridialaris chiloeensis on Different Successional Stages of Stream PeriphytonINTERNATIONAL REVIEW OF HYDROBIOLOGY, Issue 3 2004Verónica Díaz Villanueva Abstract In this study we determined grazing effects of the South Andean endemic mayfly Meridialaris chiloeensis on periphyton at different stages of successional development. Grazing effects were studied through a two-factor experimental design (colonization stages X grazer density) in a stream-side channel in spring and winter. Our results showed an absence of proportionality between grazer density and periphyton decline in response to grazers at low and intermediate levels of periphytic biomass; however, when periphyton biomass was high a direct inverse relationship was observed between post-grazing biomass and grazer density. The relationship between periphytic algae (chlorophyll a concentration) and periphyton (total periphytic ash-free dry mass) (C/OM index) was used as an estimation of the autotrophic fraction in the total periphyton matrix. Grazing did not alter the C/OM index indicating that both autotrophic and heterotrophic fractions of the periphyton components were reduced in the same proportion. Ordination of samples using the relative abundance of diatom species showed that herbivore effect was less evident at intermediate and late stage of colonization than at early one. These results support the statement that the outcome of the herbivore-periphyton interaction may depend on the successional stage of the periphyton community. In spring Fragilaria pinnata relative abundance, on the basis of cell counts, was reduced by grazing and Nitzschia palea was enhanced. In the winter experiment, grazing decreased Achnanthes minutissima relative abundance. (© 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source] Changing sources of support for women's political rights*INTERNATIONAL SOCIAL SCIENCE JOURNAL, Issue 184 2005Katherine Meyer Much research investigating changes in women's political rights focuses on the presence or absence of improvement that is evident in national and international policies or on gender proportionality in representative institutions at international, national, and local levels. Public opinion about women's rights is an important corollary to this research because it underpins the legitimacy of policies and representative bodies. However, if examined alone, changes in public opinion over time yield an incomplete picture of women's situation, just as changes in policies and representation do. Factors that lie behind statistics about trends in women's rights matter, and it is essential to figure out if the sources of support for women's political rights shift over time. We employed data from Kuwait in the years surrounding the Beijing +5 conference to illustrate how the absence of change in public opinion about women's rights can hide important social dynamics that figure into the development of policies and practices affecting women. Whereas support for women's rights was evident among the most numerous and advantaged Kuwaiti citizens in 1994, it rested less with the general public and more with citizens involved in social networks and those who had particular political and cultural agendas by 1998. [source] New directions: a South Asian perspectiveINTERNATIONAL SOCIAL SCIENCE JOURNAL, Issue 167 2001Gamini Lakshman Peiris The central challenge facing countries of the developing world such as Sri Lanka is how to reconcile ethnic and cultural diversity with the concept of mature and cohesive nationhood. This is especially so where a federation is created not by the traditional pattern of independent entities coming together, but by devolution from a unitary state to one involving power sharing. In such situations there arealways fears that federalism is a precursor of dismemberment or disintegration. What is needed is to reconcile competing objectives for a strong and effective centre and for recognition of cultural and ethnic diversity. This may require hybrid or quasi-federal structures that do not fit neatly into unitary or federal categories. In attempting to achieve this reconciliation practicalities may require asymmetrical devolution, but this in turn may provoke emotional resistance to special or disparate treatment of particular minorities. Nor is devolution by itself sufficient. To be viable there must be suitable mechanisms to resolve intergovernmental disputes. Particularly important if confrontation and polarisation are to be minimised isemphasis upon compromise and proportionality and a public respect for pluralism, secularism, and representative democracy. [source] The Right of National DefenseINTERNATIONAL STUDIES PERSPECTIVES, Issue 1 2007DAVID R. MAPEL This article argues that there are two justifications of the right of national defense. First, some states possess the right as a means of protecting legitimate domestic political institutions. Second, all states possess the right within a morally defensible form of international law. Critics have argued that the first justification does not explain why one legitimate state should have the right not to be attacked and conquered by another legitimate state. Critics have argued that the second justification does not recognize that current international law is too flawed to justify a right of national defense for all states. This article defends the right against both criticisms. It then considers the scope of the right, focusing on the issue of proportionality. The article also argues that the two justifications of the right express potentially conflicting principles of justice, which can sometimes lead to hard choices, as illustrated by the NATO intervention in Kosovo. [source] The importance of growth and mortality costs in the evolution of the optimal life historyJOURNAL OF EVOLUTIONARY BIOLOGY, Issue 6 2006D. A. ROFF Abstract A central assumption of life history theory is that the evolution of the component traits is determined in part by trade-offs between these traits. Whereas the existence of such trade-offs has been well demonstrated, the relative importance of these remains unclear. In this paper we use optimality theory to test the hypothesis that the trade-off between present and future fecundity induced by the costs of continued growth is a sufficient explanation for the optimal age at first reproduction, ,, and the optimal allocation to reproduction, G, in 38 populations of perch and Arctic char. This hypothesis is rejected for both traits and we conclude that this trade-off, by itself, is an insufficient explanation for the observed values of , and G. Similarly, a fitness function that assumes a mortality cost to reproduction but no growth cost cannot account for the observed values of ,. In contrast, under the assumption that fitness is maximized, the observed life histories can be accounted for by the joint action of trade-offs between growth and reproductive allocation and between mortality and reproductive allocation (Individual Juvenile Mortality model). Although the ability of the growth/mortality model to fit the data does not prove that this is the mechanism driving the evolution of the optimal age at first reproduction and allocation to reproduction, the fit does demonstrate that the hypothesis is consistent with the data and hence cannot at this time be rejected. We also examine two simpler versions of this model, one in which adult mortality is a constant proportion of juvenile mortality [Proportional Juvenile Mortality (PJM) model] and one in which the proportionality is constant within but not necessarily between species [Specific Juvenile Mortality (SSJM) model]. We find that the PJM model is unacceptable but that the SSJM model produces fits suggesting that, within the two species studied, juvenile mortality is proportional to adult mortality but the value differs between the two species. [source] A discrete-time hazard analysis of the exit of burley tobacco growers in Tennessee, North Carolina, and VirginiaAGRICULTURAL ECONOMICS, Issue 5 2010Kelly J. Tiller Burley tobacco; Exit; Discrete-time hazard logit; Federal tobacco program Abstract This article examines the exit and survival dynamics of burley tobacco growers in Tennessee, North Carolina, and Virginia using a discrete-time hazard logit model. The study also predicts the effects of selected farm and family characteristics on exit hazards, assesses the proportionality of their effects over time and their relative importance in explaining the variation in exit hazards among burley tobacco growers. Results provide the longitudinal progression of the probability of exiting the tobacco industry since the end of the federal tobacco program in 2004, and identify off-farm participation, percentage of farm receipts from tobacco, tobacco price, educational level, and farm size as the most important determinants of the decision to exit the tobacco industry. Further, the effects of off-farm participation and farm size on the exit hazards of burley tobacco farms are proportional over time while the effects of the percentage of farm receipts from tobacco and tobacco price are time variant. [source] Orientational analysis of planar fibre systems observed as a Poisson shot-noise processJOURNAL OF MICROSCOPY, Issue 1 2007SALME KÄRKKÄINEN Summary We consider two-dimensional fibrous materials observed as a digital greyscale image. The problem addressed is to estimate the orientation distribution of unobservable thin fibres from a greyscale image modelled by a planar Poisson shot-noise process. The classical stereological approach is not straightforward, because the point intensities of thin fibres along sampling lines may not be observable. For such cases, Kärkkäinen et al. (2001) suggested the use of scaled variograms determined from grey values along sampling lines in several directions. Their method is based on the assumption that the proportion between the scaled variograms and point intensities in all directions of sampling lines is constant. This assumption is proved to be valid asymptotically for Boolean models and dead leaves models, under some regularity conditions. In this work, we derive the scaled variogram and its approximations for a planar Poisson shot-noise process using the modified Bessel function. In the case of reasonable high resolution of the observed image, the scaled variogram has an approximate functional relation to the point intensity, and in the case of high resolution the relation is proportional. As the obtained relations are approximative, they are tested on simulations. The existing orientation analysis method based on the proportional relation is further experimented on images with different resolutions. The new result, the asymptotic proportionality between the scaled variograms and the point intensities for a Poisson shot-noise process, completes the earlier results for the Boolean models and for the dead leaves models. [source] Pore-size effects on activated-carbon capacities for volatile organic compound adsorptionAICHE JOURNAL, Issue 8 2002Mei-Chiung Huang Gas-phase adsorption of acetone and n-hexane by activated carbons with different pore structures was investigated. The carbons were prepared from a bituminous coal with KOH activation. Increasing the activation temperature increased both the porosity and pore size. The equilibrium adsorption capacity for the organic compounds increased with the carbon porosity, but not proportionally. The percentage of pore volume utilized showed a decreasing trend with the porosity development for acetone adsorption, while an increasing trend was observed for n-hexane. By incorporating pore size distribution with the Dubinin-Radushkevich equation using an inverse proportionality between the micropore size and adsorption energy, the isotherms for adsorption onto different carbons can be well predicted. Simulations indicated that the adsorption energy, which is an inverse function of the micropore size, determines the adsorption capacity. Different effects of porosity development were observed for different adsorbates. [source] Ultrasonic Velocity Technique for Nondestructive Quantification of Elastic Moduli Degradation during Creep in Silicon NitrideJOURNAL OF THE AMERICAN CERAMIC SOCIETY, Issue 5 2003Franti, ek Lofaj The ultrasonic velocity technique was used for nondestructive quantification of creep damage during interrupted tensile creep tests at 1400°C in an advanced silicon nitride to investigate the possibilities of this technique for creep damage monitoring in ceramic components. The longitudinal and shear wave velocities, Poisson's ratio, and Young's, shear, and bulk moduli linearly decreased with strain. Precise density change measurements indicated a linear relationship with a coefficient of proportionality of 0.69 between the volume fraction of cavities and tensile strain. Cavitation was identified as the main creep mechanism in the studied silicon nitride and the reason for ultrasonic velocity and elastic moduli degradation. The measurement of just the longitudinal wave velocity changes was found to be sufficient for quantification of cavitation during creep. The capability of the ultrasonic velocity technique for simple, sensitive, and reliable nondestructive monitoring of creep damage during intermittent creep was demonstrated in silicon nitride. [source] Pharmacokinetics of gamithromycin in cattle with comparison of plasma and lung tissue concentrations and plasma antibacterial activityJOURNAL OF VETERINARY PHARMACOLOGY & THERAPEUTICS, Issue 3 2010R. A. HUANG Huang, R. A., Letendre, L. T., Banav, N., Fischer, J., Somerville, B. Pharmacokinetics of gamithromycin in cattle with comparison of plasma and lung tissue concentrations and plasma antibacterial activity. J. vet. Pharmacol. Therap.33, 227,237. The pharmacokinetics (PK) and dose proportionality of gamithromycin (ZACTRAN®), a novel azalide, after a single intravenous (i.v.) dose of 3 mg/kg or subcutaneous (s.c.) injection at 3, 6 and 9 mg/kg body weight were studied in 13 male castrate and 13 female Angus cattle. Following i.v. administration, the mean area under the curve extrapolated to infinity (AUCinf) was 4.28 ± 0.536 ,g·h/mL, and mean elimination half-life (t1/2) was 44.9 ± 4.67 h, with a large volume of distribution (Vss) of 24.9 ± 2.99 L/kg and a high clearance rate (Clobs) of 712 ± 95.7 mL/h/kg. For cattle treated with s.c. injection of 3, 6 or 9 mg/kg, mean AUCinf values were 4.55 ± 0.690, 9.42 ± 1.11 and 12.2 ± 1.13 ,g·h/mL, respectively, and the mean elimination half-lives (t1/2) were 51.2 ± 6.10, 50.8 ± 3.80 and 58.5 ± 5.50 h. Gamithromycin was well absorbed and fully bioavailable (97.6,112%) after s.c. administration. No statistically significant (, = 0.05) gender differences in the AUCInf or elimination half-life values were observed. Dose proportionality was established based on AUCInf over the range of 0.5 to 1.5 times of the recommended dosage of 6 mg/kg of body weight. Further investigations were conducted to assess plasma PK, lung/plasma concentration ratios and plasma antibacterial activity using 36 cattle. The average maximum gamithromycin concentration measured in whole lung homogenate was 18 500 ng/g at first sampling time of 1 day (,24 h) after treatment. The ratios of lung to plasma concentration were 265, 410, 329 and 247 at 1, 5, 10 and 15 days postdose. The lung AUCinf was 194 times higher than the corresponding plasma AUCinf. The apparent elimination half-life for gamithromycin in lung was 90.4 h (,4 days). Antibacterial activity was observed with plasma collected at 6 h postdose with a corresponding average gamithromycin plasma concentration of 261 ng/mL. In vitro plasma protein binding in bovine plasma was determined to be 26.0 ± 0.60% bound over a range of 0.1,3.0 ,g/mL of gamithromycin. The dose proportionality of AUC, high bioavailability, rapid and extensive distribution to lung tissue and low level of plasma protein binding are beneficial PK parameters for an antimicrobial drug used for the treatment and prevention of bovine respiratory disease. [source] Pharmacokinetics of ibafloxacin following intravenous and oral administration to healthy Beagle dogsJOURNAL OF VETERINARY PHARMACOLOGY & THERAPEUTICS, Issue 2 2002M. COULET The pharmacokinetics of ibafloxacin, a new veterinary fluoroquinolone antimicrobial agent, was studied following intravenous (i.v.) and oral administration to healthy dogs. The mean absolute bioavailability of ibafloxacin after oral doses of 7.5, 15 and 30 mg/kg ranged from 69 to 81%, indicating that ibafloxacin was well absorbed by dogs. Ibafloxacin was also absorbed rapidly [time of maximum concentration (tmax) 1.5 h], reaching a mean maximum concentration (Cmax) of 6 ,g/mL at 15 mg/kg, well distributed in the body [large volume of distribution at steady state (Vss) and Varea of 1.1 L/kg and 4 L/kg, respectively], and exhibited an elimination half-life of 5.2 h and a low total body clearance (8.7 mL/min/kg). Both Cmax and area under the concentration,time curve (AUC) showed dose proportionality over the dose range tested (7.5,30 mg/kg). The pharmacokinetics of ibafloxacin was similar following single and repeated dosage regimens, implying no significant accumulation in plasma. Food promoted the absorption of ibafloxacin by increasing Cmax and AUC, but did not change tmax. High amounts of the metabolites, mainly 8-hydroxy- and, 7-hydroxy-ibafloxacin were excreted in urine and faeces, either unchanged or as glucuronide conjugates. Following oral administration of 15 mg ibafloxacin/kg, the total recovery of ibafloxacin, its metabolites and conjugates in urine and faeces was 61.9,99.9% of the dose within 48 h. [source] Millimetric properties of gamma-ray burst host galaxiesMONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Issue 3 2006R. S. Priddey ABSTRACT We present millimetre (mm) and submillimetre (submm) photometry of a sample of five host galaxies of gamma-ray bursts (GRBs), obtained using the Max Planck Millimetre Bolometer (MAMBO2) array and Submillimetre Common-User Bolometer Array (SCUBA). These observations were obtained as part of an ongoing project to investigate the status of GRBs as indicators of star formation. Our targets include two of the most unusual GRB host galaxies, selected as likely candidate submm galaxies: the extremely red (R,K, 5) host of GRB 030115, and the extremely faint (R > 29.5) host of GRB 020124. Neither of these galaxies is detected, but the deep upper limits for GRB 030115 impose constraints on its spectral energy distribution, requiring a warmer dust temperature than is commonly adopted for submillimetre galaxies (SMGs). As a framework for interpreting these data, and for predicting the results of forthcoming submm surveys of Swift -derived host samples, we model the expected flux and redshift distributions based on luminosity functions of both submm galaxies and GRBs, assuming a direct proportionality between the GRB rate density and the global star formation rate density. We derive the effects of possible sources of uncertainty in these assumptions, including (1) introducing an anticorrelation between GRB rate and the global average metallicity, and (2) varying the dust temperature. [source] Relations and disproportions: The labor of scholarship in the knowledge economyAMERICAN ETHNOLOGIST, Issue 2 2008ALBERTO CORSÍN JIMÉNEZ ABSTRACT In this article, I provide an ethnographic exploration of some of the terms for imagining knowledge in today's "knowledge society," and I attempt to situate the kind of "sociology of knowledge" behind this imagination. In particular, I am interested in the sociological imagination of knowledge in terms of a relational economy, in which knowledge flows uninterruptedly to create and shape what Yochai Benkler has dubbed "the wealth of networks." I pursue this interest through an ethnography of the production of research among humanities scholars at Spain's National Research Council (CSIC). For CSIC's human scientists, books (and other bookish analogues, such as libraries or manuscript collections) occupy a place of prominence in the institutional production of research. This economy of scholarship (between books, between people and books, and between what books do and what institutions and researchers imagine them to do) finds itself at a "disproportionate" distance from the "network economy of information" encountered in the literature on the knowledge economy and promoted in certain circles within CSIC. I contrast the epistemological economies of CSIC scientists' relational and disproportional views on research and, ultimately, attempt to provide an anthropological description of a contemporary sociology of knowledge, including its analytical categories and models. [knowledge, knowledge economy, relations, proportionality, labor, academia] [source] | ||||||||||||||||||||||||||||||||||