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Propargylic Amines (propargylic + amine)
Selected AbstractsRhodium- and Palladium-Catalyzed Hydroarylation of Propargylic Amines with Arylboronic AcidsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 2-3 2010Antonio Arcadi Abstract The hydroarylation of 3-arylprop-2-yn-1-amine derivatives with arylboronic acids has been studied in the presence of rhodium or palladium catalysts. By using a rhodium-based catalytic system, ,,,-diarylallylamines were isolated in good yields. By contrast, the formation of the regiosomeric ,,,-diarylallylamines was achieved by means of a palladium catalyst in the presence of acetic acid. The complementary regioselectivity displayed by these two processes is a consequence of different catalytic cycles, involving respectively carborhodation or hydropalladation of the coordinated alkyne as key steps. Calculated charge distributions in the ,-complexes are in accord with the results obtained. [source] Conventional Tetrakis(triphenylphosphine)palladium-Copper(I) Iodide-Catalyzed Sonogashira Coupling of Free and BOC- Protected Propargylic Amines "On Water"ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 11-12 2009Bartomeu Soberats Abstract Alkynylation of aryl iodides with propargylic amines has been achieved by means of a Sonogashira coupling using "on water" methods. The use of less than 0.2,mol% of tetrakis(triphenylphosphine)palladium [Pd(PPh3)4] and 1.5,mol% copper(I) iodide [CuI] in the presence of diisopropylethylamine (DIPEA) allows the coupling to proceed at 95,°C yielding moderate to good yields of mono-, bis-, and tris-aminoalkynylbenzene derivatives. [source] ChemInform Abstract: Copper(I)-Catalyzed Substitution Reactions of Propargylic Amines: Importance of C(sp),C(sp3) Bond Cleavage in Generation of Iminium Intermediates.CHEMINFORM, Issue 33 2010Tsuyuka Sugiishi Abstract Substitution reactions of propargylic amines using various secondary amines proceed in the presence of a copper(I) catalyst. [source] ChemInform Abstract: Conventional Tetrakis(triphenylphosphine)palladium-Copper(I) Iodide-Catalyzed Sonogashira Coupling of Free and BOC-Protected Propargylic Amines "On Water".CHEMINFORM, Issue 1 2010Bartomeu Soberats Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] PdCl2 -Catalyzed Efficient Transformation of Propargylic Amines to (E)-,-Chloroalkylidene-,-lactams.CHEMINFORM, Issue 34 2005Shengming Ma Abstract For Abstract see ChemInform Abstract in Full Text. [source] Semiconductor-Gold Nanocomposite Catalysts for the Efficient Three-Component Coupling of Aldehyde, Amine and Alkyne in WaterADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 17 2009Leng Leng Chng Abstract An efficient heterogeneous lead sulfide-gold catalyst has been successfully developed for the synthesis of propargylic amines via a three-component coupling reaction of aldehyde, amine and alkyne in water. The process is simple and applicable to a diverse range of aromatic and aliphatic aldehydes, amines and alkynes. Furthermore, the catalyst is stable to air and water, and can be easily recovered and reused. [source] Conventional Tetrakis(triphenylphosphine)palladium-Copper(I) Iodide-Catalyzed Sonogashira Coupling of Free and BOC- Protected Propargylic Amines "On Water"ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 11-12 2009Bartomeu Soberats Abstract Alkynylation of aryl iodides with propargylic amines has been achieved by means of a Sonogashira coupling using "on water" methods. The use of less than 0.2,mol% of tetrakis(triphenylphosphine)palladium [Pd(PPh3)4] and 1.5,mol% copper(I) iodide [CuI] in the presence of diisopropylethylamine (DIPEA) allows the coupling to proceed at 95,°C yielding moderate to good yields of mono-, bis-, and tris-aminoalkynylbenzene derivatives. [source] Synthesis of Trisubstituted Pyrroles from Rhodium-Catalyzed Alkyne Head-to-Tail Dimerization and Subsequent Gold- Catalyzed CyclizationADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2009Hong Mei Peng Abstract Dimerization of N -protected propargylic amines in a rather rare head-to-tail mode has been achieved under mild conditions with high selectivity using rhodium catalysts. The N -protecting group could be a sulfonyl, carbamate, or carbonyl functionality and (cyclooctadiene)rhodium chloride dimer/1,1,-bis(diphenylphosphino)ferrocene {[Rh(COD)Cl]2/dppf} as well as tris(triphenylphosphine)rhodium chloride [Rh(PPh3)3Cl] proved to be active catalysts. In addition, these functionalized gem -enynes subsequently undergo selective gold(III)-catalyzed intramolecular hydroamination to give trisubstituted pyrroles under mild conditions. [source] ChemInform Abstract: Copper(I)-Catalyzed Substitution Reactions of Propargylic Amines: Importance of C(sp),C(sp3) Bond Cleavage in Generation of Iminium Intermediates.CHEMINFORM, Issue 33 2010Tsuyuka Sugiishi Abstract Substitution reactions of propargylic amines using various secondary amines proceed in the presence of a copper(I) catalyst. [source] | ||||||||||