Home About us Contact
|
Home About us Contact | ||
|
|
||
Project
Kinds of Project Terms modified by Project Selected AbstractsEffect of Cog Threads under Rat SkinDERMATOLOGIC SURGERY, Issue 12 2005Hyo Jook Jang MD Background. The aging face loses the tensile strength of structural integrity. Cog threads have been used recently to tighten lax skin and soft tissue. Objective. A comparative study of the effects of cog, monofilament, and multifilament threads under rat skin. Methods. Each cog, monofilament, and multifilament thread was inserted under the facial skin of a cadaver and the panniculus carnosus of rat dorsal skin. The maximum holding strength (MHS) of the thread and the tearing strength of the skin around the thread were measured with a tensiometer. The thickness of the capsule around the thread and the myofibroblasts was observed histologically. Results. In the cadaver, the MHS of the cog thread was 190.7 ± 65.6 g. It was greater than that of the monofilament (22.4 ± 7.7 g) or multifilament (40.4 ± 19.7 g) thread. In the rat, the MHS of the cog thread was 95.1 ± 18.8 g. It was greater than that of the monofilament (4.3 ± 1.3 g) or multifilament (10.9 ± 2.1 g) thread in the second week. The thickness of the capsule around the cog thread was 93.0 ± 3.2 ,m. It was thicker than the monofilament thread's capsule, 39.2 ± 12.1 ,m, in the fourth week. The number of myofibroblasts presented significantly more in the cog (96.0 ± 72.4) than in the monofilament thread (4.3 ± 4.4). The rumpled in-between skin suspended by each of the three different threads returned to its original state in 2 weeks. Conclusion. The cog thread placed under the rat skin immediately pulled the skin and subcutaneous tissue. The myofibroblasts around the thread played a role in fibrous tissue contracture 4 weeks postinsertion of the thread. These findings could be the basis for clinical application. THIS STUDY WAS SUPPORTED BY A GRANT FROM THE KOREA HEALTH 21 R&D PROJECT, MINISTRY OF HEALTH AND WELFARE, REPUBLIC OF KOREA. [source] THE POTENTIAL OF THE FAMILY LAW EDUCATION REFORM PROJECT FOR FAMILY LAWYERS1FAMILY COURT REVIEW, Issue 1 2007Forrest S. MostenArticle first published online: 7 DEC 200 Family lawyers are major beneficiaries of the reforms set out in the Family Law Education Reform Project (FLER) Report. This commentary from a veteran family law practitioner explores the needs of the family law bar for the training of law students in practical, interdisciplinary, client-centered lawyering that goes beyond the traditional case method. I trace many of the current innovations evolving in family law practice and how FLER reforms will not only benefit law schools but also have a major impact in the courts and private practice sector. [source] FOREWORD TO THE SPECIAL ISSUE ON THE FAMILY LAW EDUCATION REFORM PROJECTFAMILY COURT REVIEW, Issue 4 2006Andrew Schepard First page of article [source] LIPID TREATMENT IN ETHNICALLY DIVERSE UNDERSERVED OLDER ADULTS WITH DIABETES MELLITUS: STATIN USE, GOAL ATTAINMENT, AND HEALTH DISPARITIES IN THE INFORMATICS FOR DIABETES EDUCATION AND TELEMEDICINE PROJECTJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 2 2010Ruth S. Weinstock MD No abstract is available for this article. [source] LOCAL ABORIGINAL PEOPLE'S ATTITUDES TOWARDS THE UMOONA KIDNEY PROJECT AT COOBER PEDYNEPHROLOGY, Issue 3 2000Batterham M [source] A FAITH-BASED MENTAL HEALTH AND DEVELOPMENT PROJECT FOR SLUM DWELLERS IN BRAZILANNALS OF ANTHROPOLOGICAL PRACTICE, Issue 1 2010Sidney M. Greenfield This article describes a mental health and development program being carried out under the direction of a Comboni Missionary who is an ordained Roman Catholic priest from Italy and a medical doctor presently completing a Ph.D. in psychiatry in Brazil. It is based on a theoretical framework that integrates the cultural and religious backgrounds of migrants coming into the slums of Brazilian cities with a form of group therapy based on the assumptions of Liberation Theology and the teachings of Paulo Freire that was developed by Prof. Adalberto Barreto, a practicing Brazilian trained M.D.,psychiatrist with European Ph.D.s in psychiatry and anthropology. This unusual combination of anthropological insight combined with a unique approach to group psychotherapy, rooted in a humanistic approach to religion, has resulted in an extremely effective development program that is beginning to be applied in slum areas in other parts of Brazil and elsewhere. [source] AL01 PACIFIC ISLANDS PROJECT , PAST PRESENT AND FUTUREANZ JOURNAL OF SURGERY, Issue 2007D. A. K. Watters The Pacific Islands Project began in 1995 and in its early years had a focus on providing specialist services that were not available in the 10 island nations visited. In 2002 Nauru was added and PIP Phase III will end its 9 month bridging/extension phase in September 2007. During the last 12 years Fiji School of Medicine has commenced a postgraduate medical training program in surgery similar to that has been in existence in PNG since 1975. There are now a growing number of Pacific-trained surgeons who can select suitable cases, do some of the surgery, and supervise the postoperative care. Increasingly visiting teams have focused on transferring skills and building local capabilities (capacity building). The RACS, the Project Director and the speciality coordinators have managed the first three phases of the project in Australia. Phase III had on-going evaluation by an internal RACS committee under the chairmanship of Professor Hamish Ewing. AusAid also externally reviewed the project late in 2006. That review was generally complimentary as to what has been achieved but also points to some new goals for the future. At the time of writing this abstract the future direction of PIP is yet to be decided and designed. This will be done mid 2007. However, it is to be hoped there will be a new program, focused on capacity building, that is managed in the Pacific and employs the skills of Pacific Island Specialists wherever possible. RACS is likely to continue to play an important role in sourcing visiting specialists, organising training positions, arranging courses. We have much expertise to offer but there is no longer any need for us to set the agendas. [source] THE HISTORY OF THE BROOKHAVEN NATIONAL LABORATORY PROJECT IN ARCHAEOLOGICAL CHEMISTRY, AND APPLYING NUCLEAR METHODS TO THE FINE ARTSARCHAEOMETRY, Issue 2 2007G. HARBOTTLE This paper traces the events leading up to the formation of a project in 1954, in the Chemistry Department at Brookhaven National Laboratory, dedicated to the application of those new developments that were rapidly transforming postwar nuclear science to the parallel humanistic disciplines of archaeology and the fine arts. The further evolution of this effort involved the enlightened support of the Department of Energy (then AEC and ERDA) coupled with the lively interests of the archaeological, fine-arts and art-historical communities, their professional academics and the many graduate and undergraduate students who participated in the Brookhaven project. But more than new scientific methodologies, concepts and instrumentation were deployed. What developed was a large-scale, truly interdisciplinary effort, where scholars of the humanities and sciences worked side by side in a remarkable way, each led by the other, to the mutual benefit and increase of their knowledge and understanding. A paradigm of co-operation between arts and sciences was initiated: this paper presents a record of the process and its outcome, a novel blending of science and humanism that is very much taken for granted by research workers today. [source] EVALUATION OF THE RURAL SOUTH AUSTRALIAN TRI-DIVISION ADOLESCENT HEALTH PROJECTAUSTRALIAN JOURNAL OF RURAL HEALTH, Issue 3 2003Lucio Naccarella ABSTRACT: The Adolescent Health Project (AHP) was a rural pilot project aimed at strengthening the relationship between general practitioners (GPs) and adolescents within three Divisions of general practice. The evaluation assessed the implementation of the AHP model and strategies and their impact. The AHP used a centralised management/support and local delivery model. The AHP improved GP relationships and comfort with dealing with young people, and improved GP relationships with school counsellors. Divisional relationships with local schools improved. Students reported increased knowledge about GPs, increased confidence and comfort with accessing GPs. The AHP delivered a popular project to GPs, GP clinics, schools, school counsellors and students, which built the capacity of divisions, GPs, and schools to improve adolescent health care provision. Further research questions have emerged: What are the patterns of relationships between GPs and adolescents, and between GPs and school counsellors, and what strategies work best to sustain such relationships? [source] Population pharmacokinetics of mycophenolic acid in children and young people undergoing blood or marrow and solid organ transplantationBRITISH JOURNAL OF CLINICAL PHARMACOLOGY, Issue 4 2010Lihua Zeng WHAT IS ALREADY KNOWN ABOUT THIS PROJECT? , Mycophenolate mofetil (MMF) is an immunosuppressant drug used for the treatment and prevention of graft vs. host disease in blood or marrow transplantation and acute graft rejection in solid organ transplantation. , Mycophenolic acid (MPA) pharmacokinetics have not been thoroughly studied in paediatric blood or marrow transplant recipients and guidance for optimal dosing of mycophenolic acid in children is lacking. , Mycophenolic acid exhibits considerable inter- and intra-patient pharmacokinetic variability in adults and paediatric transplant recipients. , The AUC of mycophenolic acid over a 12 h dose interval at steady-state is generally agreed to be the most reliable metric associated with the risk of acute rejection. , Population pharmacokinetic analysis can utilize concentration information from both intensive sampling and sparse sampling to provide pharmacokinetic parameter estimates, estimates of inter- individual and intra-individual variability in these parameters and allows patient characteristics explaining inter-individual variability to be quantified. WHAT THIS STUDY ADDS , This study is one of the first investigations in which a population pharmacokinetic modelling approach was applied to assess the pharmacokinetics of both intravenous and oral MMF in children and young people undergoing blood or marrow and solid organ transplantation. , Bodyweight and concomitant ciclosporin were found to influence MPA pharmacokinetics. , This study evaluated current dosing strategies and found that they may be suboptimal for children weighing less than 10 kg. AIMS To characterize the population pharmacokinetics of mycophenolic acid (MPA) and evaluate dose regimens using a simulation approach and accepted therapeutic drug monitoring targets in children and young people undergoing blood or marrow, kidney and liver transplantation. METHODS MPA concentration,time data were collected using an age specific sampling protocol over 12 h. Some patients provided randomly timed but accurately recorded blood samples. Total and unbound MPA were measured by HPLC. NONMEM was employed to analyze MPA pharmacokinetic data. Simulations (n= 1000) were conducted to assess the suitability of the MPA dose regimens to maintain total MPA AUC(0,12 h) within the range 30 and 60 mg l,1 h associated with optimal outcome. RESULTS A two-compartment pharmacokinetic model with first-order elimination best described MPA concentration,time data. Population mean estimates of MPA clearance, inter-compartmental clearance, volumes of distribution in the central and peripheral compartments, absorption rate constant and bioavailability were 6.42 l h,1, 3.74 l h,1, 7.24 l, 16.8 l, 0.39 h,1 and 0.48, respectively. Inclusion of bodyweight and concomitant ciclosporin reduced the inter-individual variability in CL from 54.3% to 31.6%. Children with a bodyweight of 10 kg receiving standard MPA dose regimens achieve an MPA AUC below the target range suggesting they may be at a greater risk of acute rejection. CONCLUSIONS The population pharmacokinetic model for MPA can be used to explore dosing guidelines for safe and effective immunotherapy in children and young people undergoing transplantation. [source] JOINT BIDDING, GOVERNANCE AND PUBLIC PROCUREMENT COSTS:A CASE OF ROAD PROJECTS,ANNALS OF PUBLIC AND COOPERATIVE ECONOMICS, Issue 3 2009Antonio Estache ABSTRACT§:,To utilize public resources efficiently, it is important to take advantage of competition in public procurement auctions to the maximum extent. Joint bidding is a common practice that potentially facilitates competition. By pooling financial and experiential resources, more firms are expected to enter the market, but it will also directly reduce competition if more than one bidder who is solely qualified makes a coalition. In theory joint bidding may or may not be beneficial to auctioneers, depending on the model. The paper empirically examines the impacts of joint bidding on firms' entry as well as bidding behaviour, using data on public road projects in developing countries. It shows that coalitional bids, in particular by local firms, would be competitive, but foreign joint ventures would undermine competition. It is also found that good governance can encourage firms' entry into the tendering and facilitate joint bidding practices. [source] A direct circuit experiment system in non-immersive virtual environments for education and entertainmentCOMPUTER APPLICATIONS IN ENGINEERING EDUCATION, Issue 2 2005Quang-Cherng Hsu Abstract This article proposes to contribute to the goal of "The Popular Science Teaching Research Project" as well as to enhance the programming abilities of mechanical engineering students. Topics being included as example are in physical science, which include battery, lamp, and electric circuit. These materials are designed, based on virtual-reality technology that is suitable for students as early as fourth-grade students of primary school. It will help the students become familiar with new computer technology and provide an opportunity to study while playing virtual reality computer games. The benefits of the developed application software system of virtual reality are virtualization of teaching equipment, cost reduction of teaching materials, unlimited teaching style, and optimization of learning procedures. © 2005 Wiley Periodicals, Inc. Comput Appl Eng Educ 13: 146,152, 2005; Published online in Wiley InterScience (www.interscience.wiley.com); DOI 10.1002/cae.20044 [source] Management Strategies and Improvement of Performance of Sewer NetworksCOMPUTER-AIDED CIVIL AND INFRASTRUCTURE ENGINEERING, Issue 7 2007Denys Breysse Even when they are conscious about the needs of maintenance to keep the system in a good condition, they lack efficient methods and tools that may help them in taking appropriate decisions. One can say that no really satisfactory and efficient tool exists, enabling the optimization of Inspection, Maintenance, or Rehabilitation (IMR) strategies on such systems. Sewer managers and researchers have been involved for many years in the French National Research Project for Renewal of Non Man Entry Sewer System (RERAU,Réhabilitation des Réseaux d'Assainissement Urbains, in French) to improve their knowledge of these systems and the management policies. During the RERAU project, a specific action has been dedicated to the modeling of asset ageing and maintenance. A special attention has been dedicated to the description of defects and dysfunctions, to the evaluation of performances and its modeling, accounting for its various dimensions (from the point of view of the manager, of the user, of the environment,). After having defined an Index of Technical Performance (ITp), we will introduce the Index of Technical and Economic Performance (ITEp) that is a combined measure of performance (including social costs) and technical costs. This index provides an objective standard tool for managers to compare different alternatives. It is used in the article to compare some simple IMR strategies. It sets the basis of a new method for no-man entry sewer system management, enabling us to analyze the profitableness of investment in terms of both technical and economic performance. [source] Modeling the Dynamics of an Infrastructure ProjectCOMPUTER-AIDED CIVIL AND INFRASTRUCTURE ENGINEERING, Issue 4 2005Long Duy Nguyen These problems result in low project performance and poor project outcome. A dynamic simulation model is proposed to capture the dynamics of construction projects in the construction phase. Eight key feedback structures from previous models of project dynamics and the unique characteristics of construction projects are identified as dynamic hypotheses. They include the structures of labor, equipment, material, labor and equipment interaction, schedule, rework, safety, and quality. Subsequently, a formal simulation model is mathematically formulated in terms of stock and flow diagrams. The model is then calibrated into a real project under construction. Part of testing indicates that the simulated behavior of the model and the actual behavior of the project are similar. This implies that the model is able to simulate the dynamics of the project and, consequently, to enhance project monitoring and control. [source] Preparing Students for Conservation Careers through Project-Based LearningCONSERVATION BIOLOGY, Issue 6 2006Jeremy A. Martinich First page of article [source] A COMPARISON OF MEXICAN MIGRANT REMITTANCES ACROSS U.S. REGIONSCONTEMPORARY ECONOMIC POLICY, Issue 3 2008STEPHEN T. FAIRCHILD Since 1990, the United States has experienced a geographic dispersion of Mexican migrants from traditional gateways to new regions. Using data from the Mexican Migration Project, we find significant differences in both the likelihood of remitting and the amount remitted by Mexican migrants across U.S. regions. Specifically, Mexican migrants living in U.S. regions that have experienced considerable increases in migrant populations since 1990 (the Northeast, Southeast, Mountain, and Midwest regions) remit at higher rates and in larger quantities than migrants living in more traditional migrant destinations (the Pacific and South Central regions), even after controlling for observed differences in migrant populations. (JEL F22, F32, J11, R23) [source] Corporate environmental disclosures about the effects of climate changeCORPORATE SOCIAL RESPONSIBILITY AND ENVIRONMENTAL MANAGEMENT, Issue 6 2008Elizabeth Stanny Abstract We examine factors associated with the US S&P 500 firms' decisions to disclose information about the current and projected effects of climate change to institutional investors. Through the Carbon Disclosure Project, 315 institutional investors representing 41 trillion USD in assets asked the largest public firms to respond to a questionnaire about climate change. We explore whether firms' disclosures directed specifically to institutional investors are related to factors that have been found to explain voluntary disclosures to investors in general. In particular, we consider factors related to the level of scrutiny, since extant literature predicts that the cost of not disclosing increases with level of scrutiny. We find that size, previous disclosures and foreign sales are related to whether firms disclose information about climate change requested by institutional investors through the Carbon Disclosure Project. Copyright © 2008 John Wiley & Sons, Ltd and ERP Environment. [source] Predictive, concurrent, prospective and retrospective validity of self-reported delinquencyCRIMINAL BEHAVIOUR AND MENTAL HEALTH, Issue 3 2003Darrick Jolliffe Background The self-report method is widely used to measure offending. Previous studies suggest that it is generally valid, but that its validity may be lower for blacks than for whites. Aim To assess the validity of self-reported offending in relation to court referrals, and to investigate how it varies with types of offences, sex and race. Method Annual court and self-report data were collected between ages 11 and 17 for eight offences in the Seattle Social Development Project, which is a prospective longitudinal survey of 808 youths. Results Self-reports predicted future court referrals. Predictive validity was highest for drug offences, for males and for whites, and lowest for females and Asians. The probability of youths with a court referral reporting offences and arrests was highest for drug offences, for males, for whites and for blacks. Retrospective ages of onset agreed best with prospective ages for drug offences, Asians and whites. More Asians than blacks or whites failed retrospectively to report offences that had been reported prospectively. Conclusions The validity of self-reports of offending was high, especially for drug offences, for males and for whites. Contrary to prior research, validity was high for black males. It was lowest for Asian females. Sex and race differences in validity held up after controlling for socioeconomic status. Differential validity probability did not reflect police bias. Copyright © 2003 Whurr Publishers Ltd. [source] DESTINATION EFFECTS: RESIDENTIAL MOBILITY AND TRAJECTORIES OF ADOLESCENT VIOLENCE IN A STRATIFIED METROPOLIS,CRIMINOLOGY, Issue 3 2010PATRICK SHARKEY Two landmark policy interventions to improve the lives of youth through neighborhood mobility,the Gautreaux program in Chicago and the Moving to Opportunity (MTO) experiments in five cities,have produced conflicting results and have created a puzzle with broad implications: Do residential moves between neighborhoods increase or decrease violence, or both? To address this question, we analyze data from a subsample of adolescents ages 9,12 years from the Project on Human Development in Chicago Neighborhoods, a longitudinal study of children and their families that began in Chicago,the site of the original Gautreaux program and one of the MTO experiments. We propose a dynamic modeling strategy to separate the effects of residential moving across three waves of the study from dimensions of neighborhood change and metropolitan location. The results reveal countervailing effects of mobility on trajectories of violence; whereas neighborhood moves within Chicago lead to an increased risk of violence, moves outside the city reduce violent offending and exposure to violence. The gap in violence between movers within and outside Chicago is explained not only by the racial and economic composition of the destination neighborhoods but also by the quality of school contexts, adolescents' perceived control over their new environment, and fear. These findings highlight the need to simultaneously consider residential mobility, mechanisms of neighborhood change, and the wider geography of structural opportunity. [source] MODELING MEDIATION IN THE ETIOLOGY OF VIOLENT BEHAVIOR IN ADOLESCENCE: A TEST OF THE SOCIAL DEVELOPMENT MODEL,CRIMINOLOGY, Issue 1 2001BU HUANG The social development model seeks to explain human behavior through specification of predictive and mediating developmental relationships. It incorporates the effects of empirical predictors ("risk factors" and "protective factors") for antisocial behavior and seeks to synthesize the most strongly supported propositions of control theory, social learning theory, and differential association theory. This article examines the fit of the social development model using constructs measured at ages 10, 13, 14, and 16 to predict violent behavior at age 18. The sample of 808 is from the longitudinal panel of the Seattle Social Development Project, which in 1985 surveyed fifth-grade students from schools serving high crime neighborhoods in Seattle, Washington. Structural equation modeling techniques were used to examine the fit of the model to the data. The model fit the data (CFI ,.90, RMSEA ,.05). We conclude that the social development model adequately predicts violence at age 18 and mediates much of the effect of prior violence. Implications for theory and for prevention are discussed. [source] GOVERNMENTALITY, LANGUAGE IDEOLOGY, AND THE PRODUCTION OF NEEDS IN MALAGASY CONSERVATION AND DEVELOPMENTCULTURAL ANTHROPOLOGY, Issue 2 2007PAUL W. HANSON Integrated conservation and development program planning pivots on a critical exchange. In establishing protected areas, part of the subsistence base of resident people is enclosed. Residents are then offered assistance in meeting needs emerging from the enclosure. The elicitation and interpretation of need in such programs forms a technology of governance. This article analyzes differing linguistic ideologies underpinning needs production in Madagascar's Ranomafana National Park Project, arguing that the technology of needs production is part of a green neoliberal rationality through which the Malagasy state and its citizens are being transformed, and from which an increasingly sophisticated countergovernmentality grows. [source] Anti-Colonialist Antinomies in a Biology Lesson: A Sonata-Form Case Study of Cultural Conflict in a Science ClassroomCURRICULUM INQUIRY, Issue 3 2003Paokong John Chang This case study illustrates and analyzes the tension an ESL science teacher encountered when his science curriculum came into conflict with the religious and cosmological beliefs of one of his Hmong immigrant students. A Hmong immigrant himself, the teacher believes the science he is teaching is important for all his students to learn. He also understands how his science curriculum can be one part of an array of cultural forces that are adversely affecting the Hmong community. The case study examines this tension, but does not resolve it. Instead, the study explores the knowledge the teacher draws upon to respond to the tension in a caring and constructive manner. This knowledge includes the teacher's understanding of science and pedagogy. It also includes his understanding of Hmong history, which enables him to hear what his science curriculum means to one of his students. The case study concludes that teachers need some knowledge of the history of students' specific cultural groups in order to teach science well to all students. This case study was one of seven produced by the Fresno Science Education Equity Teacher Research Project. It uses a special format, a "sonata-form case study," to highlight tensions between specific curricular imperatives and meeting broader student needs. The study is based on real experiences, and employs composite characters and fictionalized dialogue to make its conceptual point. A theoretical preface explaining the methods of research and the modes of representation used in the Fresno Project is included. [source] Plasmodium falciparum myosins: Transcription and translation during asexual parasite development,CYTOSKELETON, Issue 4 2005Jacqueline Chaparro-Olaya Abstract Six myosins genes are now annotated in the Plasmodium falciparum Genome Project. Malaria myosins have been named alphabetically; accordingly, we refer to the two latest additions as Pfmyo-E and Pfmyo-F. Both new myosins contain regions characteristic of the functional motor domain of "true" myosins and, unusually for P. falciparum myosins, Pfmyo-F encodes two consensus IQ light chain-binding motifs. Phylogenetic analysis of the 17 currently known apicomplexan myosins together with one representative of each myosin class clusters all but one of the apicomplexan sequences together in Class XIV. This refines the earlier definition of the Class XIV Subclasses XIVa and XIVb. RT-PCR on blood stage parasite mRNA amplifies a specific product for all six myosins and each shows developmentally regulated transcription. Thus: Pfmyo-A and Pfmyo-B genes are transcribed throughout development; Pfmyo-C is predominant in trophozoites; Pfmyo-D occurs in trophozoites and schizonts; Pfmyo-E though barely present in earlier stages is abundant in schizonts; Pfmyo-F increases steadily throughout development and maturation. It is known that Pfmyo-A and Pfmyo-B are synthesised during late schizogony and we now show that Pfmyo-D expression is also temporally regulated to late trophozoites and schizonts where it distributes close to segregating nuclei. Thus, in asexual stages myosin synthesis does not always parallel transcript accumulation, showing that translation is also regulated. The implication is that the mRNAs are either subjected to turnover, synthesised and degraded, or that they are sequestered in an inactivate form until required for protein synthesis. Cell Motil. Cytoskeleton 60:200,213, 2005. © 2005 Wiley-Liss, Inc. [source] Depression, desperation, and suicidal ideation in college students: results from the American Foundation for Suicide Prevention College Screening Project at Emory UniversityDEPRESSION AND ANXIETY, Issue 6 2008Ph.D., Steven J. Garlow M.D. Abstract The objective of this investigation was to examine suicidal ideation and depression in undergraduate college students who participated in the American Foundation for Suicide Prevention-sponsored College Screening Project at Emory University. The principal measure of depressive symptoms was the nine-item depression module from the Patient Health Questionnaire (PHQ-9). Additional questions were focused on current suicidal ideation, past suicide attempts, and episodes of deliberate self-harm and on symptoms of anxiety and distress. Seven hundred and twenty-nine students participated over a 3-school-year interval (2002,2005). Most notably, 11.1% of the students endorsed current (past 4 weeks) suicidal ideation and 16.5% had a lifetime suicide attempt or self-injurious episode. Students with current suicidal ideation had significantly higher depression symptom severity than those without suicidal ideation (t = ,9.34, df = 706, P<.0001, d = 1.9), and 28.5% of the students with PHQ-9 scores of 15 or higher reported suicidal ideation compared to 5.7% of those with lower scores (,2 = 56.29, df = 1, P<.0001, two-tailed). Suicidal ideation was prominently associated with symptoms of desperation (odds ratio 2.6, 95% CI 1.5,4.6, P<.001). The vast majority of students with moderately severe to severe depression (85%) or current suicidal ideation (84%) were not receiving any psychiatric treatment at the time of assessment. These results suggest that there is a strong relationship between severity of depressive symptoms and suicidal ideation in college students, and that suicidal feelings and actions are relatively common in this group. This underscores the need to provide effective mental health outreach and treatment services to this vulnerable population. As this analysis was based on data collected at a single institution, the results may not be representative of all college students or young adults. Depression and Anxiety 0:1,7, 2007. © 2007 Wiley-Liss, Inc. [source] Dermo quiz: the illness and death of Anna Maria Lodovica de' Medici, Palatine Electress (1667,1743)DERMATOLOGIC THERAPY, Issue 2010L. Cataliotti ABSTRACT According to the unpublished documents, preserved in the Archives, the authors provide a possible explanation of the disease of the Anna Maria Lodovica de' Medici, the last descendent of the famous Florentine dynasty, suggesting that she could not have suffered from breast cancer, as it was claimed, but that she could have contracted syphilis. The opportunity to exhume her corpse in the frame of the Medici Project will supply evidence for this interpretation. [source] Payments for Ecosystem Services in Nicaragua: Do Market-based Approaches Work?DEVELOPMENT AND CHANGE, Issue 3 2010Gert Van Hecken ABSTRACT The concept of Payments for Ecosystem Services (PES) is gaining increasing attention among scholars as well as conservation and development practitioners. The premises of this innovative conservation approach are appealing: private land users, usually poorly motivated to protect nature on their land, will do so if they receive payments from environmental service buyers which cover part of the land users' opportunity costs of developing the land. However, this article warns against an over-enthusiastic adoption of a one-sided market-based PES approach. Based on a field study of the Regional Integrated Silvopastoral Approaches to Ecosystem Management Project (RISEMP), one of the main PES pilot projects in Nicaragua, it suggests that a mixture of economic and non-economic factors motivated farmers to adopt the envisaged silvopastoral practices and that the actual role of PES is mistakenly understood as a simple matter of financial incentives. The authors argue that PES approaches should be understood as a part of a broader process of local institutional transformation rather than as a market-based alternative for allegedly ineffective government and/or community governance. [source] The next exclusion debate: Assessing technology, ethics, and intellectual disability after the human genome projectDEVELOPMENTAL DISABILITIES RESEARCH REVIEW, Issue 2 2007Kelly M. Munger Abstract Recent scientific discoveries have made it much easier to test prenatally for various genetic disabilities, such as Down syndrome. However, while many observers have heralded such "advances" for their effectiveness in detecting certain conditions, others have argued that they perpetuate discrimination by preventing the birth of children with disabilities. This article examines the ethical and social implications of the Human Genome Project for individuals with intellectual disabilities and their families. It details the critique of prenatal testing articulated by many disability rights activists as well as scholarly and professional responses to that critique. A review of the pertinent research literature includes perspectives of genetic professionals, ethicists, disability studies scholars, parents of children with disabilities, and disabled individuals themselves. Finally, the article explores how future research endeavors, policies, and practices may more effectively integrate and respect the positions of these various stakeholders. © 2007 Wiley-Liss, Inc. MRDD Research Reviews 2007;13:121,128. [source] Universal newborn screening and adverse medical outcomes: A historical noteDEVELOPMENTAL DISABILITIES RESEARCH REVIEW, Issue 4 2006Jeffrey P. Brosco Abstract Universal newborn screening programs for metabolic disorders are typically described as a triumph of medicine and public policy in the US over the last 50 years. Advances in science and technology, including the Human Genome Project, offer the opportunity to expand universal newborn screening programs to include many additional metabolic and genetic conditions. Although the benefits of such screening programs appear to outweigh their costs, some critics have claimed that historical examples of inadvertent harm ensuing from false-positive screening results and subsequent inappropriate medical treatment should make us wary of expanding universal newborn screening. In this essay, we report the results of a review of the published literature to assess whether the extension of screening from at risk populations to all newborns led to substantial morbidity and mortality from misguided medical treatment. We provide a historical overview of universal newborn screening programs in the United States, and then focus on six early NBS programs: congenital hypothyroidism, phenylketonuria, congenital adrenal hyperplasia, galactosemia, sickle cell disease, and maple syrup urine disease. Our comprehensive search of published sources did not reveal a widespread problem of harm ensuing from medical treatment of children with false positive screening test results. © 2006 Wiley-Liss, Inc. MRDD Research Reviews 2006;12:262,269. [source] Two distinct forms of minor neurological dysfunction: perspectives emerging from a review of data of the Groningen Perinatal ProjectDEVELOPMENTAL MEDICINE & CHILD NEUROLOGY, Issue 8 2002Mijna Hadders-Algra MD PhD First page of article [source] Residual risk for acute stroke in patients with type 2 diabetes and hypertension in primary care: Skaraborg Hypertension and Diabetes ProjectDIABETES OBESITY & METABOLISM, Issue 5 2006K. Junga Aim:, The aim of this study was to investigate the risk of acute stroke in subgroups of patients treated for hypertension and type 2 diabetes in primary care. Methods:, Patients with hypertension only (n = 695), type 2 diabetes only (n = 181) or both (n = 240), who consecutively attended an annual control in primary care in Skara, Sweden during 1992,1993, were evaluated for cardiovascular disease risk factors and enrolled in this study. Subjects with neither hypertension nor type 2 diabetes (n = 824) who participated in a population survey in the same community served as controls. Possible events of acute stroke through 2002 were validated using hospital records and death certificates. Results:, During a mean follow-up time of 8.4 years, 190 first events of acute stroke, fatal or non-fatal, were ascertained. Risk factor levels were generally higher in all patient categories than in controls. Stroke risk was significantly increased in all male patients: hazard ratio 4.2 (95% CI 2.1,8.4) in patients with both conditions, 3.3 (1.5,7.0) in those with type 2 diabetes alone and 2.8 (1.5,5.3) in those with hypertension alone (adjusted for age, total cholesterol, current smoking, BMI and physical activity). Corresponding findings in women were 2.9 (1.5,5.8) in patients with type 2 diabetes only and 2.4 (1.2,4.7) in those with both conditions. However, in women with hypertension only, a significant risk was seen first when subjects were truncated at 85 years of age. There were too few fatal stroke events for conclusive results on stroke mortality. Conclusions:, A considerable risk of acute stroke remains in patients with type 2 diabetes and hypertension. Strategies for stricter multiple risk factor interventions should be implemented in primary care. [source] | |||||||||||||||||||||||||||||||||||||||||||||||||||||||