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Primary Materials (primary + material)
Selected AbstractsThe Oxford Edition of Donne's Letters: Well UnderwayLITERATURE COMPASS (ELECTRONIC), Issue 2 2009Margaret Maurer This paper introduces a Literature Compass panel cluster on the forthcoming Oxford edition of Donne's letters. Offering papers by the three editors, this cluster seeks to examine the new directions the edition will pursue. The papers were originally delivered to the members of the John Donne Society in Baton Rouge, Louisiana, in February 2008. The cluster is made up of the following articles: ,The Oxford Edition of Donne's Letters: Well Underway', Margaret Maurer, Literature Compass 5 (2008), DOI: 10.1111/j.1741-4113.2008.00598.x. ,"Apparitions, and Ghosts": H(a)unting Donne's Letters', M. Thomas Hester, Literature Compass 5 (2008), DOI: 10.1111/j.1741-4113.2008.00599.x. ,"Only in Obedience" to Whom? , The Identity of a Donne Correspondent', Dennis Flynn, Literature Compass 5 (2008), DOI: 10.1111/j.1741-4113.2008.00600.x. ,Problems in Editing John Donne's Letters: Unreliable Primary Materials', Ernest W. Sullivan, II, Literature Compass 5 (2008), DOI: 10.1111/j.1741-4113.2008.00601.x. [source] ,Apparitions, and Ghosts': H(a)unting Donne's LettersLITERATURE COMPASS (ELECTRONIC), Issue 2 2009M. Thomas Hester This paper is part of a Literature Compass panel cluster on the forthcoming Oxford edition of Donne's letters. Margaret Maurer introduces the cluster which offers papers by the three editors and seeks to examine the new directions the edition will pursue. The papers were originally delivered to the members of the John Donne Society in Baton Rouge, Louisiana, in February 2008. The cluster is made up of the following articles: ,The Oxford Edition of Donne's Letters: Well Underway', Margaret Maurer, Literature Compass 5 (2008), DOI: 10.1111/j.1741-4113.2008.00598.x. ,"Apparitions, and Ghosts": H(a)unting Donne's Letters', M. Thomas Hester, Literature Compass 5 (2008), DOI: 10.1111/j.1741-4113.2008.00599.x. ,"Only in Obedience" to Whom? , The Identity of a Donne Correspondent', Dennis Flynn, Literature Compass 5 (2008), DOI: 10.1111/j.1741-4113.2008.00600.x. ,Problems in Editing John Donne's Letters: Unreliable Primary Materials', Ernest W. Sullivan, II, Literature Compass 5 (2008), DOI: 10.1111/j.1741-4113.2008.00601.x. *** One way in which we might (in part) approach the problem of establishing the canon of Donne's familiar letters is indicated through a brief review of two of what Donne called his epistolary ,apparitions, and ghosts', letters lacking ,a convenient handsome body of news. . . . spun out of nothing' (Letters 121), two letters, that is, that lack (or at first hand seem to lack) any substantial internal data beyond their style that would identify them as Donne's: (a) his problematic letter ,To the Lady G.' (first printed in Marriott's 1635 Poems); and (b) the transcription of the unsigned, unaddressed, and undated ,I promised a iorney' in the even more problematic ,Burley MS'. An examination of the approach of both nineteenth- and twentieth-century readings of the first letter provides an example of how we can determine Donne's authorship of the second letter through particular attention to the style of these two representative letters. [source] Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: An approach to identify candidate genes involved in tumor developmentGENES, CHROMOSOMES AND CANCER, Issue 6 2009Edoardo Missiaglia Rhabdomyosarcomas (RMS) are the most common pediatric soft tissue sarcomas. They resemble developing skeletal muscle and are histologically divided into two main subtypes; alveolar and embryonal RMS. Characteristic genomic aberrations, including the PAX3 - and PAX7-FOXO1 fusion genes in alveolar cases, have led to increased understanding of their molecular biology. Here, we determined the effect of genomic copy number on gene expression levels through array comparative genomic hybridization (CGH) analysis of 13 RMS cell lines, confirmed by multiplex ligation-dependent probe amplification copy number analyses, combined with their corresponding expression profiles. Genes altered at the transcriptional level by genomic imbalances were identified and the effect on expression was proportional to the level of genomic imbalance. Extrapolating to a public expression profiling dataset for 132 primary RMS identified features common to the cell lines and primary samples and associations with subtypes and fusion gene status. Genes identified such as CDK4 and MYCN are known to be amplified, overexpressed, and involved in RMS tumorigenesis. Of the many genes identified, those with likely functional relevance included CENPF, DTL, MYC, EYA2, and FGFR1. Copy number and expression of FGFR1 was validated in additional primary material and found amplified in 6 out of 196 cases and overexpressed relative to skeletal muscle and myoblasts, with significantly higher expression levels in the embryonal compared with alveolar subtypes. This illustrates the ability to identify genes of potential significance in tumor development through combining genomic and transcriptomic profiles from representative cell lines with publicly available expression profiling data from primary tumors. © 2009 Wiley-Liss, Inc. [source] LCC,The economic pillar of sustainability: Methodology and application to wastewater treatmentENVIRONMENTAL PROGRESS & SUSTAINABLE ENERGY, Issue 4 2003Gerald Rebitzer Industrial applications of supply chain cost management, along with life cycle costing of goods and services, are increasing. Several industrial sectors, in particular the automotive, electronics, and primary materials, have engaged in programs to coordinate upstream and downstream activities to reduce environmental burdens. At the same time, there is an increasing need to pass on information on product, material, and energy flows along the supply chain, as well as to provide data on the use and end-of-life phases of goods and services. Therefore, methods to analyze, assess, and manage these flows, from an economic as well as an environmental perspective, are of essential importance, particularly in established large-scale industries where suppliers are increasingly challenged to provide comprehensive cost and environmental information. In this context, a life cycle costing analysis (LCC), conducted as part of life cycle management activities, can provide important opportunities. Therefore, this paper focuses on a life cycle assessment (LCA)-based LCC method, which utilizes an LCA model as a basis for cost estimations in product development and planning. A case study on life cycle costing of wastewater treatment illustrates the practical use and benefits of the method. [source] Teaching & Learning Guide for: The Origins of the Civil WarHISTORY COMPASS (ELECTRONIC), Issue 4 2007Nicole Etcheson Author's Introduction The author argues that slavery is the root cause of the Civil War even though historians have often posited other explanations. Some other interpretations have been ideological (i.e., about the morality of slavery), others have been economic, political, or cultural. Focus Questions 1If you were to make an argument for the causes of the Civil War, what evidence or types of evidence would you want to examine? 2In what ways can the different types of arguments (ideological, economic, political, and cultural), be combined to explain the causes of the Civil War? Do such arguments exclude or reinforce each other? In what ways? Author Recommends * E. L. Ayres, In the Presence of Mine Enemies: War in the Heart of America, 1859,1863 (New York, NY: Norton, 2003). A study of two counties, one north and one south, during the end of the sectional crisis and the early Civil War. While Potter, Walther, and Wilentz offer sweeping, often political, histories, Ayres offers a microhistory approach to the sectional conflict. Although Ayres writes within the tradition of seeing cultural differences between North and South, he concludes that slavery was the issue that drove the two sections apart. * M. A. Morrison, Slavery and the American West: The Eclipse of Manifest Destiny and the Coming of the Civil War (Chapel Hill, NC: University of North Carolina Press, 1997). Views the development of the sectional crisis through the lens of Manifest Destiny. Territorial expansion drove hostility between the sections. Morrison concentrates on the political developments of the period connected to the acquisition and organization of the territories to show how the issue of slavery in the territories polarized the sections. * D. M. Potter, The Impending Crisis, 1848,1861 (New York, NY: Harper & Row, 1976). The most comprehensive survey of the decade before the war. Potter traces the development of slavery as a political issue that North and South could not resolve. While it is a masterly and nuanced treatment of the political history, it does not incorporate social history and is more detailed than is useful for most undergraduates. E. H. Walther, The Shattering of the Union: America in the 1850s (Wilmington, Scholarly Resources, 2004) has recently supplanted Potter as a survey of the decade. It is an easier read for undergraduates and incorporates the new literature than has emerged since Potter wrote. * S. Wilentz, The Rise of American Democracy: Jefferson to Lincoln (New York, NY: Norton, 2005). A sweeping history of the United States from the constitutional era to the outbreak of the Civil War. Wilentz attempts to update Arthur M. Schlesinger Jr.'s synthesis The Age of Jackson by returning to a focus on the evolution of democracy while at the same time incorporating the social history that emerged after Schlesinger wrote. Only the last third of this very long book covers the 1850s, but Wilentz argues that democracy had taken differing sectional forms by that period: a free-labor version in the North and a plantation version in the South. Online Materials 1. The Valley of the Shadow: Two Communities in the American Civil War (http://valley.vcdh.virginia.edu/) A prize-winning website that profiles Augusta County, Virginia and Franklin County, Pennsylvania. Material from this website formed the basis of Ayres, In the Presence of Mine Enemies. Although the website primarily concentrates on the Civil War itself, it provides access to newspapers and letters and diaries from the 1850s that show the development of, and reaction to, the sectional crisis in those counties. It also shows students the types of materials (census, tax, and church records as well as newspapers and letters and diaries) with which historians work to build an argument. 2. American Memory from the Library of Congress (http://memory.loc.gov/ammem/index.html) Although not specifically devoted to the origins of the Civil War, the American Memory site provides access to the collections of the Library of Congress which contain massive amounts of primary materials for students and scholars. From the website, one can gain access to congressional documents, periodicals from the 1850s, nineteenth-century books, music, legal documents, memoirs by white and black southerners as well as slave narratives. Sample Syllabus Nicole Etcheson's ,Origins of the Civil War,' History Compass, 3/1 (2005), doi:10.1111/j.1478-0542.2005.00166.x can be used as a reading in any Civil War course. [source] Potentials and constraints of the farmer-to-farmer programme for environmental protection in NicaraguaLAND DEGRADATION AND DEVELOPMENT, Issue 2 2003S. Hawkesworth Abstract The natural environment in Nicaragua has been damaged by rural development policies geared for the export of cash crops, by uneven land distribution and the near absence of concerns about the environmental effects of the prevailing model of development. The demands made by market forces for the export of primary materials have been reasons for land degradation in the big farms, and the need to survive a poverty stricken existence has forced the peasantry to damage the marginal and fragile land they worked. Successive governments did not address these underlying causes of environmental degradation, and even the opportunities afforded by the environment programme that resulted from the 1979 Sandinista revolution, did not result in significant environmental improvements. The paper briefly considers the constraints faced by the Sandinista administration and how the farmer-to-farmer programme (Campesino-a-Campesino) was brought about as a result of the impacts of the Sandinista era. The substantive part of the paper considers PCAC's significance as an agroecological programme and its advantages and limitations for improving peasants' livelihoods via dissemination of land-protective measures. The viability of the programme is assessed by field work carried out examining in detail the case of three communities, and the paper concludes that the gains made in environmental protection and conservation are in jeopardy without structural policy changes. The paper proposes that for the programme to improve its potential, adequate political will, power and organization are necessary to facilitate greater access to secure land tenure among the peasantry. Copyright © 2003 John Wiley & Sons, Ltd. [source] | ||||||||||