THE PHILOSOPHICAL QUARTERLY, Issue 218 2005
Krista Lawlor
Ruth Millikan has long argued that the phenomenon of confused thought requires us to abandon certain traditional programmes for mental semantics. On the one hand she argues that confused thought involves confused concepts, and on the other that Fregean senses, or modes of presentation, cannot be useful in theorizing about minds capable of confused thinking. I argue that while we might accept that concepts can be confused, we have no reason to abandon modes of presentation. Making sense of confused thought requires recognizing modes of presentation. [source]

COMMUNITY, CONTEXT, AND THE PRESENTATION OF SELF IN DISTRIBUTED WORKPLACE INTERACTION

ANNALS OF ANTHROPOLOGICAL PRACTICE, Issue 1 2008
Michael Youngblood
Instantaneous communications technology has made it possible for distant coworkers to be interconnected to an unprecedented degree. Despite this, distributed workers often feel deeply disconnected from the production and performance of conventional workplace relationships and workplace culture. As the knowledge economy workforce trends toward ever-greater distribution and globalization, this raises important questions about the practice and experience of creative coengagement by colleagues who are not proximate to each other in time and space. How are shared understandings of workers' behavioral norms disseminated and practiced when workers are physically isolated from the collective workspace? How are relationships of collegiality and hierarchy constructed and performed through increasingly narrow channels of social interaction? How do workers signal their energy and commitment to a collective creative enterprise when their actual productive activity is largely invisible to others with whom and for whom they work? This article draws on my research with distributed knowledge workers, informal observations of colleagues, and personal experiences working as an independent consultant in distributed settings. It focuses on the challenges these workers face in defining their workplace community and effectively representing their professional selfhood when working at a distance. In this article I suggest that one key to alleviating these challenges is to extend the attributes of "placehood" to distant work spaces. [source]

NEUROLOGICAL DEFICIT AS A PRESENTATION OF OCCULT METASTATIC THYROID CARCINOMA

ANZ JOURNAL OF SURGERY, Issue 10 2006
Mark Izzard
Three cases of occult metastatic thyroid carcinoma presenting with neurological deficits are reviewed. In each case the patient's initial presentation was with symptoms of neurological deficiency secondary to a spinal cord compression. All patients received a combination of surgery, external beam radiotherapy and postoperative thyroxine treatment. Two of the three patients are alive and well, able to mobilize with minor neurological dysfunction. The diagnosis and management of the patients, as well as their outcomes are reviewed, with a discussion on further management issues alongside a review of the current published work. [source]

XXVII International Congress of the International Academy of Pathology October 12-17, 2008, Athens, Greece POSTER PRESENTATIONS

HISTOPATHOLOGY, Issue 2008
Article first published online: 24 SEP 200
First page of article [source]

Society for Oral Physiology Store Kro Group

JOURNAL OF ORAL REHABILITATION, Issue 9 2002
Article first published online: 3 OCT 200
ABSTRACTS OF SELECTED PRESENTATIONS Editorial note The Abstracts give early recognition to some recent scientific studies. They are reproduced on the understanding that the material has not been previously published. Individual authors should be contacted for details of their experimental method and analytical approach to their results before any conclusions are judged and quoted. [source]

MODERATED (ORAL) POSTER PRESENTATIONS

THE JOURNAL OF SEXUAL MEDICINE, Issue 2010
Article first published online: 2 SEP 2010
First page of article [source]

EPIDIDYMAL TUBERCULOSIS: PRESENTATIONS AND DIAGNOSIS

ANZ JOURNAL OF SURGERY, Issue 6 2007
Pranshu Bhargava MB BS
No abstract is available for this article. [source]

Application of Visual Analytics for Thermal State Management in Large Data Centres

COMPUTER GRAPHICS FORUM, Issue 6 2010
M. C. Hao
I.3.3 [Computer Graphics]: Picture/Image Generation,Display Algorithms; H.5.0 [Information Systems]: Information Interfaces and Presentation,General Abstract Today's large data centres are the computational hubs of the next generation of IT services. With the advent of dynamic smart cooling and rack level sensing, the need for visual data exploration is growing. If administrators know the rack level thermal state changes and catch problems in real time, energy consumption can be greatly reduced. In this paper, we apply a cell-based spatio-temporal overall view with high-resolution time series to simultaneously analyze complex thermal state changes over time across hundreds of racks. We employ cell-based visualization techniques for trouble shooting and abnormal state detection. These techniques are based on the detection of sensor temperature relations and events to help identify the root causes of problems. In order to optimize the data centre cooling system performance, we derive new non-overlapped scatter plots to visualize the correlations between the temperatures and chiller utilization. All these techniques have been used successfully to monitor various time-critical thermal states in real-world large-scale production data centres and to derive cooling policies. We are starting to embed these visualization techniques into a handheld device to add mobile monitoring capability. [source]

Recent Developments and Applications of Haptic Devices

COMPUTER GRAPHICS FORUM, Issue 2 2003
S. D. Laycock
Abstract Over recent years a variety of haptic feedback devices have been developed and are being used in a number of important applications. They range from joysticks used in the entertainment industry to specialised devices used in medical applications. This paper will describe the recent developments of these devices and show how they have been applied. It also examines how haptic feedback has been combined with visual display devices, such as virtual reality walls and workbenches, in order to improve the immersive experience. ACM CSS: H.5.2 Information Interfaces and Presentation,Haptic I/O; I.3.8 Computer Graphics,Applications; I.6 Simulation and Modelling,Applications [source]

A Case Report of Rapid Progressive Coarctation and Severe Middle Aortic Syndrome in an Infant with Williams Syndrome

CONGENITAL HEART DISEASE, Issue 5 2009
E. Kevin Hall MD
ABSTRACT Williams syndrome is a genetic disorder caused by multiple contiguous gene deletions in chromosome 7. Presentation in early life is most often a result of luminal stenosis of right- and left-sided arterial vasculature. We report the case of a newborn infant who had a rapidly progressing diffuse form of arteriopathy that required two surgeries and one percutaneous balloon dilation within the first 2 months of her life. [source]

Late Presentation of Pulmonary Valve Stenosis Confirmed by Cardiovascular Magnetic Resonance

CONGENITAL HEART DISEASE, Issue 3 2008
Didier Locca MD
ABSTRACT We describe the case of a 70-year-old man who presented with increasing exertional dyspnea. He was found to have an ejection systolic murmur and evidence of right ventricular outflow tract obstruction, with a peak velocity of 4.5 m/s recorded by transthoracic Doppler echocardiography. Cardiovascular magnetic resonance showed right ventricular hypertrophy, pulmonary valve stenosis, peak recorded velocity 4.2 m/s, with thickened pulmonary valve leaflets of reduced mobility, and poststenotic dilatation of the main pulmonary artery. The case illustrates that severe pulmonary valve stenosis can present late in life and that cardiovascular magnetic resonance can be useful in clarifying nature and level of right ventricular outflow tract obstruction in an adult. [source]

Coronary Artery Fistulas: A Review of the Literature and Presentation of Two Cases of Coronary Fistulas with Drainage into the Left Atrium

CONGENITAL HEART DISEASE, Issue 3 2007
Scott Ceresnak MD
Abstract We report 2 cases of infants presenting with a murmur shortly after birth and diagnosed with coronary artery fistulas with drainage into the left atrium. The first infant had a fistulous communication between the left main coronary artery and the left atrial appendage and presented with signs and symptoms of heart failure. The infant was repaired surgically in the first week of life. The second infant was asymptomatic and had a fistulous communication between the right coronary artery and the left atrium. The infant will have the fistula closed in the cardiac catheterization laboratory when the child is older. The literature on coronary artery fistulas is reviewed, and the diagnosis and management of coronary artery fistulas is discussed. [source]

Mucoepidermoid/Adenosquamous Carcinoma of the Skin: Presentation of Two Cases

DERMATOLOGIC SURGERY, Issue 12 2001
Darlene S. Johnson MD
Background. Mucoepidermoid carcinoma is a relatively common neoplasm of the major and minor salivary glands comprising 10,30% of primary carcinomas. They may involve the skin through direct extension, metastases, and rarely, as a primary focus (adenosquamous carcinoma). Objective. To discuss through case reports, the nomenclature, histology, clinical course, and treatment of mucoepidermoid/adenosquamous carcinoma. Methods. We present a case of mucoepidermoid carcinoma primary to an upper eyelid accessory lacrimal gland with direct cutaneous extension and a case of primary cutaneous adenosquamous carcinoma of the scalp. Results. An eyelid neoplasm of lacrimal origin was initially treated with Mohs micrographic surgery (MMS), requiring an orbital exenteration to achieve a tumorfree plane. In the second case, a primary scalp lesion was cleared with MMS. Neither patient has had local recurrence or metastases. Conclusion. Correct diagnosis is crucial to pursuing adequate treatment for this aggressive neoplasm. We support the use of MMS to achieve local control. [source]

Acinetobacter Endocarditis Presenting as a Large Right Atrial Mass: An Atypical Presentation

ECHOCARDIOGRAPHY, Issue 4 2010
Sherrita Bhagan-Bruno M.D.
This paper discusses a 26-year-old woman with end-stage renal disease on hemodialysis and Acinetobacter calcoaceticus-baumannii complex endocarditis. The patient had an indwelling right internal jugular catheter that was probably the nidus of infection. Transthoracic echocardiogram revealed an atypical presentation of the endocarditis as a large intracardiac mass, measuring in centimeters and occupying more than 50% of the right atrial cavity. The mass was attached to the lateral wall of the right atrium without valvular involvement. The patient was treated with prompt removal of the indwelling catheter, intravenous antibiotics, and surgical resection of the mass with an uneventful recovery. A literature search for cases of "Acinetobacter endocarditis" reveals this as the first case reported of Acinetobacter endocarditis presenting in this manner. (Echocardiography 2010;27:E39-E42) [source]

Lesions of the Mitral Valve as a Cause of Central Retinal Artery Occlusion: Presentation and Discussion of Two Cases

ECHOCARDIOGRAPHY, Issue 1 2010
Maryam Ayati M.D.
We present two cases of mitral valve lesions that manifested with unilateral blindness caused by central retinal artery occlusion (CRAO): Case 1. A 68-year-old woman was admitted to our clinic for sudden blindness. Retinal artery angiogram showed CRAO. Transthoracic and transesophageal echocardiography (TEE) documented a mass attached to the ventricular side of the posterior mitral leaflet, which at pathology was identified as a blood cyst. Case 2. A 67-year-old man was admitted for a sudden unilateral painless loss of vision. Retinal angiogram documented CRAO, and TEE showed a highly mobile, spherical, lesion on the atrial side of anterior mitral leaflet. In this case, the pathological finding was a degenerated calcified thrombosis. We report on two cases of very rare abnormalities of the mitral valve presenting with a very rare embolic complication, i.e., CRAO. Like for cryptogenic stroke, transesophageal echocardiography plays a central role in the diagnosis of cardiogenic embolic sources. (Echocardiography 2010;27:E1-E3) [source]

Unusual Left Atrial Appendage Mass: Atypical Presentation of Papillary Fibroelastoma

ECHOCARDIOGRAPHY, Issue 5 2008
Miroslawa Jablonski-Cohen M.D.
Papillary fibroelastomas are small, histologically benign neoplasms that are typically found on the valvular endocardium. We report a patient with a papillary fibroelastoma in an unusual location: the left atrial appendage. Although the mass was visualized both by computed tomography (CT) and transesophageal echocardiography, the diagnosis was histologically confirmed after surgical excision. [source]

Has the Clinical Presentation and Clinician's Index of Suspicion of Cardiac Tamponade Changed Over the Past Decade?

ECHOCARDIOGRAPHY, Issue 3 2008
Sachin Gandhi M.D.
It remains unclear whether advances in the understanding of the pathophysiology and improvements in cardiovascular imaging over the years have impacted the clinician's recognition of cardiac tamponade (CT). We sought to evaluate signs and symptoms of CT in a present-day population and compare it to a similar group from a decade prior. We performed a retrospective analysis of two cohorts of patients presenting to a tertiary hospital with CT, all of whom underwent pericardial drainage (PD). Group 1 (Gp1) included subjects presenting from 1988 to 1991 and Group 2 (Gp2) included subjects from 2002 to 2005. Fifty-five patients comprised each group, with an average age of 55 years. Seventy-one percent of patients in Gp1 had identifiable cardiovascular symptoms 1 week prior to presentation, compared to 33% in Gp2. Dyspnea was the most common symptom in both groups, and was less frequent in Gp2. Compared with Gp1, chest pain, cough, and lethargy were also less frequent in Gp2. One day prior to PD, tachypnea and pulsus paradoxus were detected more frequently in Gp1 compared to Gp2. Large, circumferential pericardial effusions were the most frequent echocardiographic findings in both groups and the most common etiology of CT was malignancy in Gp1and postoperative bleeding in Gp2. Thus, the recognition of symptoms and physical signs in patients presenting with CT has changed over the past decade, as has etiology of pericardial effusions. However, the diagnosis of CT still remains delayed, and the present data emphasize the need for a heightened index of suspicion for recognizing this hemodynamically-important process. [source]

Fibrosing TB Mediastinitis Presenting as a Superior Vena Cava Syndrome: A Case Presentation and Echocardiogram Correlate

ECHOCARDIOGRAPHY, Issue 7 2006
Lidiette Esquivel M.D.
A 49-year-old woman developed a chronic obstruction of the superior vena cava (SVC) as a complication of mediastinal tuberculosis. Echocardiography findings are presented along with the cavography. Symptoms disappeared after stenting the fibrosed SVC. Transesophageal echocardiogram findings led to the condition's final resolution. [source]

Phialemonium curvatum Prosthetic Valve Endocarditis with an Unusual Echocardiographic Presentation

ECHOCARDIOGRAPHY, Issue 6 2006
Azriel Osherov M.D.
Phialemonium species, an opportunistic fungal pathogen rarely causes invasive disease, have been described as opportunistic infection agents in humans, mainly as a result of immunosuppression and very rarely involves the heart. We present a case of a patient with Phialemonium curvatum prosthetic aortic valve endocarditis with an unusual initial transesophageal echocardiography (TEE) presentation, illustrating the important role of repeat TEE for the proper diagnosis and management of infective endocarditis. [source]

Awarding Entrepreneurship Research: A Presentation of the Global Award

ENTREPRENEURSHIP THEORY AND PRACTICE, Issue 3 2009
Pontus Braunerhjelm
On January 29, 2009, professor Scott A. Shane, Case Western Reserve University (Cleveland, Ohio), became the first recipient of the Global Award for Entrepreneurship Research, an upgrade of the previous award given annually since 1996, and since then firmly established as the leading prize for outstanding research contributions in the area. The objective of this essay is to present the background to and the organizations behind the award; to describe how candidates are nominated, evaluated, and selected; and to give a clear account of the criteria that guide the Prize Committee in their selection of award winners. [source]

Surveillance of Infectious Disease Occurrences in the Community: An Analysis of Symptom Presentation in the Emergency Department

ACADEMIC EMERGENCY MEDICINE, Issue 7 2003
Joe Suyama MD
Objectives: To determine the effectiveness of a simulated emergency department (ED)-based surveillance system to detect infectious disease (ID) occurrences in the community. Methods: Medical records of patients presenting to an urban ED between January 1, 1999, and December 31, 2000, were retrospectively reviewed for ICD-9 codes related to ID symptomatology. ICD-9 codes, categorized into viral, gastrointestinal, skin, fever, central nervous system (CNS), or pulmonary symptom clusters, were correlated with reportable infectious diseases identified by the local health department (HD). These reportable infectious diseases are designated class A diseases (CADs) by the Ohio Department of Health. Cross-correlation functions (CCFs) tested the temporal relationship between ED symptom presentation and HD identification of CADs. The 95% confidence interval for lack of trend correlation was 0.0 ± 0.074; thus CCFs > 0.074 were considered significant for trend correlation. Further cross-correlation analysis was performed after chronic and non-community-acquirable infectious diseases were removed from the HD database as a model for bioterrorism surveillance. Results: Fifteen thousand five hundred sixty-nine ED patients and 6,489 HD patients were identified. Six thousand two hundred eight occurrences of true CADs were identified. Only 87 (1.33%) HD cases were processed on weekends. During the study period, increased ED symptom presentation preceded increased HD identification of respective CADs by 24 hours for all symptom clusters combined (CCF = 0.112), gastrointestinal symptoms (CCF = 0.084), pulmonary symptoms (CCF = 0.110), and CNS symptoms (CCF = 0.125). The bioterrorism surveillance model revealed increased ED symptom presentation continued to precede increased HD identification of the respective CADs by 24 hours for all symptom clusters combined (CCF = 0.080), pulmonary symptoms (CCF = 0.100), and CNS symptoms (CCF = 0.120). Conclusions: Surveillance of ED symptom presentation has the potential to identify clinically important ID occurrences in the community 24 hours prior to HD identification. Lack of weekend HD data collection suggests that the ED is a more appropriate setting for real-time ID surveillance. [source]

Presentation, diagnosis and post mortem evaluation of musculoskeletal neoplasia in a 14-year-old Warmblood gelding

EQUINE VETERINARY EDUCATION, Issue 1 2004
M. J. Head
First page of article [source]

Does Lateral Presentation of the Palmate Antlers During Fights by Fallow Deer (Dama dama L.) Signify Dominance or Submission?

ETHOLOGY, Issue 5 2002
Dómhnall J. Jennings
A central aim of the study of animal communication is to identify the mode and content of information transferred between individuals. The lateral presentation of the antler palm between male fallow deer has been described as either a signal of individual quality or an attempt to avoid fighting. In the first case two phenotypic features have been proposed by which transmission of individual quality may be facilitated. These are antler size and antler symmetry. The alternative hypothesis proposes that the lateral presentation of antlers occurs as a consequence of averting a threatening posture and may signify a reluctance to fight. We examined whether mature fallow deer use lateral palm presentation as a display during fights to indicate antler size and symmetry. We found no relationship between presentation rate of the antler and antler size and symmetry. Furthermore, males did not preferentially present their larger antler to their opponent. We also investigated whether the rate at which males presented antlers laterally during a fight was related to their ability to win the fight. Our results show that the male who performed more presentations during a fight was more likely to lose it. There were behavioural differences in the way in which a bout of presentation ended; subsequent losers tended to turn their body away from their opponent and subsequent winners tended to lower their antlers to an opponent which we interpret as an invitation to continue fighting. We conclude that the lateral palm presentation serves to de-escalate fighting between mature fallow deer. It is not a mechanism by which to communicate individual quality but rather an indication that a male is less committed to continuing investment in the current contest. [source]

Monogenic diabetes: information seeking and genetic testing access via e-mail

EUROPEAN DIABETES NURSING, Issue 2 2010
M Shepherd RGN, PhD Honorary Clinical Senior Lecturer
Abstract Background: Confirmation of monogenic diabetes by molecular genetic testing has allowed many patients, often previously assumed to have type 1 diabetes, to transfer from insulin injections to sulphonylurea tablets, with improvements in glycaemic control and quality of life: www.diabetesgenes.org provides information about monogenic diabetes and genetic testing. Aim: To investigate key issues raised by individuals who e-mailed the monogenic diabetes team about genetic testing and monogenic diabetes management. Methods: Sixty e-mail enquiries, received over a six-month period from patients and professionals worldwide, were analysed using a qualitative thematic content approach. Results: Five themes emerged: 1. Accessing genetic technology: patients and professionals both enquired about access to testing; 2. Presentation of evidence: medical facts presented by patients and professionals included characteristics specifically relevant to diagnosing monogenic diabetes; 3. Experiences of healthcare: patients often researched their condition online and some felt dissatisfied with routine consultations; 4. Seeking specialist advice regarding treatment: specific information was sought relating to management of neonatal diabetes or monogenic diabetes and pregnancy; 5. Searching for a cure through genetic technology: patients questioned whether genetic advances would lead to a cure for diabetes. Conclusion: This project offers the first insights into use of e-mail as a means of gaining access to a specialist monogenic team and information about genetic testing. Although providing advice via e-mail can prove complicated, particularly when received from patients under the care of other clinicians, it is an efficient means of communicating specialist knowledge. Study findings will aid development of a ,frequently asked questions' section of www.diabetesgenes.org. Copyright © 2010 FEND [source]

Alterations in behaviour and glutamate transmission following presentation of stimuli previously associated with cocaine exposure

EUROPEAN JOURNAL OF NEUROSCIENCE, Issue 11 2001
Gregory Hotsenpiller
Abstract To study the role of glutamate in cocaine-conditioned responses, we developed a rat model in which conditioned locomotion is produced by repeated pairing of cocaine with discrete stimuli (flashing light and metronome). ,Paired' subjects received cocaine (15 mg/kg) prior to six exposures to stimuli for 30 min in the test environment. ,Unpaired' subjects received equivalent presentations of the stimuli yet received cocaine in home cages. Tests with the stimuli alone demonstrated that the conditioned locomotion displayed by Paired subjects was evident at 3 or 10 days post-training and resistant to two sessions of testing. The degree of conditioned locomotion was not correlated with the subjects' response to novelty or cocaine. Administration of the noncompetitive AMPA receptor antagonist GYKI 52466 (2.5 mg/kg, a dose without effect on spontaneous activity) attenuated the expression of conditioned activity. In vivo microdialysis revealed that Paired subjects had significantly lower basal glutamate levels in the nucleus accumbens (NAc) than did Unpaired subjects when no stimuli were presented. Presentation of the conditioned stimuli resulted in significant increases in glutamate levels in the NAc in the Paired group whilst glutamate levels in the Unpaired group remained unchanged. The associative control of glutamate levels in the NAc by stimuli formerly paired with a drug of abuse is an unprecedented finding. It is likely to reflect the convergence of excitatory inputs that the NAc receives from limbic structures. [source]

The Construction and Presentation of Performance Indicators in executive Agency External Reports

FINANCIAL ACCOUNTABILITY & MANAGEMENT, Issue 3 2000
Brian A. Rutherford
For a variety of reasons, factors affecting the understandability and comparability of performance indicators, and perceptions of their status, may differ from those applying in the case of profit-seeking sector financial statements. This study examines the construction and presentation of performance indicators from the perspective of understandability, comparability and perceived importance. It identifies a number of aspects of reporting practice which may undermine these qualities. [source]

Multifunctional Dendrimer-Templated Antibody Presentation on Biosensor Surfaces for Improved Biomarker Detection

ADVANCED FUNCTIONAL MATERIALS, Issue 3 2010
Hye Jung Han
Abstract Dendrimers, with their well-defined globular shape and high density of functional groups, are ideal nanoscale materials for templating sensor surfaces. This work exploits dendrimers as a versatile platform for capturing biomarkers with improved sensitivity and specificity. The synthesis, characterization, fabrication, and functional validation of the dendrimer-based assay platform are described. Bifunctional hydroxyl/thiol-functionalized G4-polyamidoamine (PAMAM) dendrimer is synthesized and immobilized on the polyethylene-glycol (PEG)-functionalized assay plate by coupling PEG-maleimide and dendrimer thiol groups. Simultaneously, part of the dendrimer thiol groups are converted to hydrazide functionalities. The resulting dendrimer-modified surface is coupled to the capture antibody in the Fc region of the oxidized antibody. This preserves the orientation flexibility of the antigen binding region (Fv) of the antibody. To validate the approach, the fabricated plates are further used as a solid phase for developing a sandwich-type enzyme-linked immunosorbent assay (ELISA) to detect IL-6 and IL-1,, important biomarkers for early stages of chorioamnionitis. The dendrimer-modified plate provides assays with significantly enhanced sensitivity, lower nonspecific adsorption, and a detection limit of 0.13,pg,mL,1 for IL-6 luminol detection and 1.15,pg,mL,1 for IL-1, TMB detection, which are significantly better than those for the traditional ELISA. The assays were validated in human serum samples from a normal (nonpregnant) woman and pregnant women with pyelonephritis. The specificity and the improved sensitivity of the dendrimer-based capture strategy could have significant implications for the detection of a wide range of cytokines and biomarkers since the capture strategy could be applied to multiplex microbead assays, conductometric immunosensors, and field-effect biosensors. [source]