Premature Closure (premature + closure)

Distribution by Scientific Domains


Selected Abstracts


Premature closure of the TUCSON trial: Stroke research is not for the faint of heart,

ANNALS OF NEUROLOGY, Issue 1 2009
Patrick D. Lyden MD
No abstract is available for this article. [source]


Cranial deformations in an Iron Age population from Münsingen-Rain, Switzerland

INTERNATIONAL JOURNAL OF OSTEOARCHAEOLOGY, Issue 4 2008
A. Kutterer
Abstract The aim of this paper is an examination of cranial fluctuating asymmetry (FA) and deformations in the prehistoric population of Münsingen-Rain (La Tène period, Switzerland). The material consists of 76 skulls. Three cases of craniosynostosis, one scaphocephalic skull with complete obliteration of the sagittal suture and two plagiocephalic skulls were identified. CT scans showed that premature closure of the frontosphenoidal suture caused these plagiocephalies. For three asymmetrically deformed skulls, differential diagnosis indicates torticollis (wry neck). Another four skulls exhibit strongly developed asymmetries of the cranium and mandible, but an aetiological diagnosis was not possible. In order to evaluate the degree of fluctuating asymmetry of the population, landmarks of the skulls were digitally measured in 3D and angle calculations were made. A reference group of 30 skulls was used for comparison. Copyright © 2007 John Wiley & Sons, Ltd. [source]


Fetal hydrops associated with spontaneous premature closure of ductus arteriosus

PATHOLOGY INTERNATIONAL, Issue 9 2006
Takeshi Kondo
A 36-year-old woman presenting with fetal growth restriction in the 25th week of gestation was referred to Kobe University Hospital where hydrops fetalis was detected. A stillborn fetus, 2012 g in weight and 40 cm in height, was delivered in the 33rd week of gestation. The mother had no past history of non-steroidal anti-inflammatory drug (NSAID) use during the pregnancy. The male fetus showed maceration without macroscopic anomalies, but it was markedly edematous with bilateral pleural effusion and massive ascites. The autopsy revealed an enlarged heart and aortic coarctation in the region of the ductus arteriosus. A mild form of aortic coarctation and premature closure of the ductus arteriosus with fibrous thickening of the wall were observed. The lungs were atelectatic with vascular dilatation and congestion. This is the first documented case of hydrops fetalis caused by spontaneous premature closure of the ductus arteriosus concomitant with aortic coarctation. The findings suggest that some form of idiopathic, or spontaneous, closure of the ductus arteriosus can be one of the causes of chronic fetal heart failure, coarctation of the aorta, and fetal hydrops. [source]


The difficulty with experience: Does practice increase susceptibility to premature closure?

THE JOURNAL OF CONTINUING EDUCATION IN THE HEALTH PROFESSIONS, Issue 3 2006
Kevin W. Eva PhD
Abstract Introduction: A recent review of the physician performance literature concluded that the risk of prematurely closing one's diagnostic search increases with years of experience. To minimize confounding variables and gain insight into cognitive issues relevant to continuing education, the current study was performed to test this conclusion. Methods: Physician participants were shown a series of case histories and asked to judge the probability of a pair of diagnoses. The order in which features were presented was manipulated across participants and the probabilities compared to determine the impact of information order. Two groups of participants were recruited, 1 older than and 1 younger than 60 years. Results: The probability assigned to a diagnosis tended to be greater when features consistent with that diagnosis preceded those consistent with an alternative than when the same features followed those consistent with the alternative. Older participants revealed a greater primacy effect than less experienced participants across 4 experimental conditions. Discussion: Physicians with greater experience appear to weigh their first impressions more heavily than those with less experience. Educators should design instructional activities that account for experience-specific cognitive tendencies. [source]