Home About us Contact
|
Home About us Contact | ||
|
|
||
Postoperative Ileus (postoperative + ileus)
Selected AbstractsPostoperative ileus: a preventable event (Br J Surg 2000; 87: 1480-93)BRITISH JOURNAL OF SURGERY (NOW INCLUDES EUROPEAN JOURNAL OF SURGERY), Issue 4 2001S. Sunil No abstract is available for this article. [source] Alvimopan, a selective peripherally acting , -opioid antagonist,NEUROGASTROENTEROLOGY & MOTILITY, Issue 2 2005M. Camilleri Abstract, Alvimopan is a novel, peripherally acting , -opioid antagonist that is being developed for the management of acute postoperative ileus and for the reversal of the delayed gastrointestinal and colonic transit that result in symptoms such as constipation, nausea and motility disorders in patients treated with opiate analgesics. There is a clinical need for effective medications for the treatment of postoperative ileus and opiate-induced constipation and other motility disorders. This review addresses the basic and applied pharmacology and current evidence for the use of the medication, alvimopan, in clinical gastroenterology. [source] Opioids and the gut: pharmacology and current clinical experienceNEUROGASTROENTEROLOGY & MOTILITY, Issue 4 2004H. U. De Schepper Abstract, This article reviews the pharmacology and physiology of opiate receptors and the current and potential uses of opioid agonists and antagonists in clinical gastroenterology. ,-receptors are involved in motor and sensory functions, and their modulation is established for treatment of diarrhea. ,-antagonists have potential to reverse endogenous (e.g., postoperative ileus) or iatrogenic dysmotility (e.g., opioid bowel dysfunction). Modulation of the function of ,-receptors may be a novel approach to control visceral pain in functional gut disorders. Results of formal testing of novel opioid modulators are keenly awaited. [source] Is mechanical bowel preparation necessary in patients undergoing cystectomy and urinary diversion?BJU INTERNATIONAL, Issue 9 2002M. Shafii Objective,To compare the surgical outcome in patients with or with no bowel preparation before cystectomy and ileal conduit urinary diversion, specifically assessing local and systemic complications. Patients and methods,All patients undergoing cystectomy and ileal conduit urinary diversion between January 1991 and December 1999 were assessed retrospectively. Twenty-two receive no bowel preparation (group 1) and were compared with 64 who had (group 2). Patients had similar demographic characteristics, stage and grade of tumour. Patients in group 2 received a standard 4-day bowel preparation and group 1 received no lavage or enemas. All patients underwent a standard iliac and obturator lymph node dissection, and cystoprostatectomy or anterior exenteration and ileal conduit urinary diversion. All patients received intraoperative metronidazole and gentamicin intravenously, and two further doses after surgery. Results,Deaths after surgery were comparable in the two groups (two in group 1 and four in group 2) and the incidence of wound infection was similar (three and seven, respectively). There were no significant differences between the respective groups for fistula and anastomotic dehiscence (two and six) or sepsis (three and six). Group 2 had a higher incidence of wound dehiscence (one) than in group 1 (none). The incidence of prolonged postoperative ileus was lower in group 1 (one vs 12), as was the length of hospital stay (31.6 days vs 22.8 days). Conclusions,Bowel preparation had no advantage for the surgical outcome but it increased the length of hospital stay. [source] Randomized clinical trial of the impact of early enteral feeding on postoperative ileus and recovery (Br J Surg 2007; 94: 555,561)BRITISH JOURNAL OF SURGERY (NOW INCLUDES EUROPEAN JOURNAL OF SURGERY), Issue 8 2007M. Gatt No abstract is available for this article. [source] | ||||||||||