Possible Reasons (possible + reason)

Distribution by Scientific Domains
Distribution within Medical Sciences

Kinds of Possible Reasons

  • one possible reason
  • several possible reason


  • Selected Abstracts


    Cardiac arrhythmia during propofol sedation

    EMERGENCY MEDICINE AUSTRALASIA, Issue 5 2008
    Robert J Douglas
    Abstract Recent articles have described the increasing frequency of use of propofol as a sedating agent in the ED, and praise the safety profile of propofol when used in this manner. We describe a patient who developed torsade de pointes followed by ventricular fibrillation while undergoing propofol sedation for closed reduction of a mid-shaft fracture of the tibia and fibula. Possible reasons for the event are discussed, and suggestions are made for areas of further research. [source]


    Best available techniques (BAT) in the Finnish pulp and paper industry , a critical review

    ENVIRONMENTAL POLICY AND GOVERNANCE, Issue 3 2005
    Kimmo Silvo
    Abstract In this multiple-case study the BAT-associated techniques and relative emission levels presented in the EU's best available techniques (BAT) reference document for the pulp and paper industry (PP-BREF) are compared with the techniques applied and the relative emission levels achieved in the Finnish pulp and paper industry. Information on the emissions of 24 Finnish pulp and paper plants was compiled from the national databases maintained by the Finnish Environment Institute. Moreover, a supportive study was conducted on the use of the PP-BREF in the environmental permitting process. The techniques applied in the studied plants represented the BAT as defined in the PP-BREF to a high degree, but the emission levels showed a larger variation. Possible reasons for this variation were discussed. A BAT emission index (BEI) was designed to trace the degree to which the BAT-associated emission levels were achieved as a whole. The BEI appeared to be a useful indicator for assessing the BAT-related environmental performance of the plants. An important area for improvement, identified from the point of view of the applicability of the PP-BREF in the permit process, was the information on waste management issues. Moreover, a consistent cross-media assessment in the PP-BREF was called for. Copyright © 2005 John Wiley & Sons, Ltd and ERP Environment. [source]


    Variability in the spawning habitat of Pacific sardine (Sardinops sagax) off southern and central California

    FISHERIES OCEANOGRAPHY, Issue 6 2003
    Ronald J. Lynn
    Abstract The spatial pattern of sardine spawning as revealed by the presence of sardine eggs is examined in relation to sea surface temperature (SST) and mean volume backscatter strength (MVBS) measured by a 150 kHz acoustic Doppler current profiler (ADCP) during four spring surveys off central and southern California in 1996,99. Studies in other regions have shown that MVBS provides an excellent measure of zooplankton distribution and density. Zooplankton biomass as measured by survey net tows correlates well with concurrently measured MVBS. The high along-track resolution of egg counts provided by the Continuous Underway Fish Egg Sampler (CUFES) is a good match to the ADCP-based data. Large interannual differences in the pattern and density of sardine eggs are clearly related to the concurrently observed patterns of surface temperature and MVBS. The strong spatial relationship between sardine eggs and MVBS is particularly evident because of the large contrast in zooplankton biomass between the 1998 El Niño and 1999 La Niña. The inshore distribution of sardine spawning appears to be limited by the low temperatures of freshly upwelled waters, although the value of the limiting temperature varies between years. Often there is an abrupt offshore decrease in MVBS that is coincident with the offshore boundary of sardine eggs. Possible reasons for this association of sardine eggs and high zooplankton biomass include an evolved strategy that promotes improved opportunity of an adequate food supply for subsequent larval development, and/or adult nutrient requirements for serial spawning. Hence, the distribution of these parameters can be used as an aid for delineating the boundaries of sardine spawning habitat. [source]


    U.S. Spanish on the Air: Good Waves for the Classroom?

    FOREIGN LANGUAGE ANNALS, Issue 5 2001
    Carmen Villegas Rogers EdD
    Using segments of programming taped from stations in eight US. states, the researchers compiled data on the presence of Anglicisms in commercials and announcements; commentaries and discussions; and news, weather, and traffic reporting. Possible reasons for the use of these Anglicisms and the effect that the phenomenon might have on the maintenance of Spanish within the Latino community are discussed, The authors suggest ways in which these samples of authentic speech might be used in the classroom to present not only the idealized speech of the so-called "educated native speaker," but also dynamic and current models of interlocutors from many nations, interacting effectively as they transmit and receive information in the language. [source]


    Critical periods in the life cycle and the effects of a severe spate vary markedly between four species of elmid beetles in a small stream

    FRESHWATER BIOLOGY, Issue 8 2006
    J. M. ELLIOTT
    Summary 1. The chief objectives were: (i) to describe quantitatively the life cycles of four species of Elmidae, Elmis aenea, Esolus parallelepipedus, Oulimnius tuberculatus and Limnius volkmari; (ii) to use life tables to identify critical periods for survival in the life cycle of each species; (iii) to evaluate the immediate and longer-term effects of a severe spate on densities of the four species. Monthly samples were taken over 63 months at two contrasting sites in a small stream: one in a deep section with macrophytes abundant, and the other in a shallow stony section. 2. There were five larval instars for O. tuberculatus, seven for L. volkmari and six for the other two species. The life cycle of each species took 1 year from egg hatching (chiefly in June for E. aenea and O. tuberculatus, and July for the other species) to pupation in the stream bank and a further year before the adults in the stream matured and laid their eggs. Mature adults were present in most months, but were rare or absent in January and February and attained maximum densities in April for O. tuberculatus and May for the other species. 3. Laboratory experiments provided data on egg hatching and pupation periods and the number of eggs laid per female. Life tables compared maximum numbers per square metre for key life-stages. Within each species, mortality rates between adjacent life-stages were fairly constant among six cohorts and between sites, in spite of large differences in numbers. The only exception for all species was the high adult, but not larval, mortality during a severe spate. 4. Standardised life tables, starting with 1000 eggs, identified key life-stages with the highest mortality, namely the early life-stages for E. aenea (36% mortality), start of the overwintering period to pupation for O. tuberculatus (41%) and L. volkmari (51%), start of pupation to the maximum number of immature adults for E. parallelepipedus (41%) and between the maximum numbers of immature and mature adults for O. tuberculatus (41%). Therefore, critical periods for survival in the life cycle differed between species, presumably because of their different ecological requirements. Similarly, the effects of the spate on adult mortality, and hence egg production, varied between species, being most severe and long-term for E. aenea and O. tuberculatus, less severe for E. parallelepipedus and least severe with a rapid recovery for L. volkmari. Possible reasons for these discrepancies are discussed, but more data are required on the food and microhabitat requirements of the elmids before satisfactory explanations can be found. [source]


    Relationships between picophytoplankton and environmental variables in lakes along a gradient of water colour and nutrient content

    FRESHWATER BIOLOGY, Issue 4 2003
    Stina Drakare
    SUMMARY 1. Biomass and production of picophytoplankton, phytoplankton and heterotrophic bacterioplankton were measured in seven lakes, exhibiting a broad range in water colour because of humic substances. The aim of the study was to identify environmental variables explaining the absolute and relative importance of picophytoplankton. In addition, two dystrophic lakes were fertilised with inorganic phosphorus and nitrogen, to test eventual nutrient limitation of picophytoplankton in these systems. 2. Picophytoplankton biomass and production were highest in lakes with low concentrations of dissolved organic carbon (DOC), and DOC proved the factor explaining most variation in picophytoplankton biomass and production. The relationship between picophytoplankton and lake trophy was negative, most likely because much P was bound in humic complexes. Picophytoplankton biomass decreased after the additions of P and N. 3. Compared with heterotrophic bacterioplankton, picophytoplankton were most successful at the clearwater end of the lake water colour gradient. Phytoplankton dominated over heterotrophic bacteria in the clearwater systems possibly because heterotrophic bacteria in such lakes are dependent on organic carbon produced by phytoplankton. 4. Compared with other phytoplankton, picophytoplankton did best at intermediate DOC concentrations; flagellates dominated in the humic lakes and large autotrophic phytoplankton in the clearwater lakes. 5. Picophytoplankton were not better competitors than large phytoplankton in situations when heterotrophic bacteria had access to a non-algal carbon source. Neither did their small size lead to picophytoplankton dominance over large phytoplankton in the clearwater lakes. Possible reasons include the ability of larger phytoplankton to float or swim to reduce sedimentation losses and to acquire nutrients by phagotrophy. [source]


    Optimized La0.6Sr0.4CoO3,, Thin-Film Electrodes with Extremely Fast Oxygen-Reduction Kinetics

    ADVANCED FUNCTIONAL MATERIALS, Issue 19 2009
    Judith Januschewsky
    Abstract La0.6Sr0.4CoO3,, (LSC) thin-film electrodes are prepared on yttria-stabilized zirconia (YSZ) substrates by pulsed laser deposition at different deposition temperatures. The decrease of the film crystallinity, occurring when the deposition temperature is lowered, is accompanied by a strong increase of the electrochemical oxygen exchange rate of LSC. For more or less X-ray diffraction (XRD)-amorphous electrodes deposited between ca. 340 and 510,°C polarization resistances as low as 0.1,, cm2 can be obtained at 600,°C. Such films also exhibit the best stability of the polarization resistance while electrodes deposited at higher temperatures show a strong and fast degradation of the electrochemical kinetics (thermal deactivation). Possible reasons for this behavior and consequences with respect to the preparation of high-performance solid oxide fuel cell (SOFC) cathodes are discussed. [source]


    Studies on ,precarious rocks' in the epicentral area of the AD 1356 Basle earthquake, Switzerland

    GEOPHYSICAL JOURNAL INTERNATIONAL, Issue 2 2005
    Peter Schürch
    SUMMARY For the first time precarious rocks have been analysed in the epicentral area of the AD 1356 Basle earthquake in northern Switzerland. Several cliff sites in flat-lying, thickly bedded Upper Jurassic coral limestones in the Jura Mountains were investigated. Seven blocks are regarded as precarious with respect to earthquake strong ground motions. The age of these precarious rocks could not be determined directly as for instance by radiometric dating methods; however, based on slope degradation processes it can be concluded that the formation of these blocks predates the AD 1356 Basle earthquake. The acceleration required to topple a precarious rock from its pedestal is estimated using geometrical data for individual block sections and earthquake strong-motion records from stations on rock sites in the European Strong-Motion Database as input data for the computer program ROCKING V1.0 from the Seismological Laboratory, University of Nevada, Reno. The calculations indicate that toppling of a precarious rock largely depends on earthquake strength but also on the frequency spectrum of the signal. Although most investigated precarious rocks are surprisingly stable for ground motions similar to those expected to have occurred during the AD 1356 Basle earthquake, at least two blocks are clearly precariously balanced, with peak toppling accelerations lower than 0.3 g. Possible reasons why these blocks did not topple during the AD 1356 Basle earthquake include incomplete separation from their base, sliding of precarious rocks, their size, lower than assumed ground accelerations and/or duration of shaking. [source]


    Stereochemical Models for Discussing Additions to ,,, -Unsaturated Aldehydes Organocatalyzed by Diarylprolinol or Imidazolidinone Derivatives , Is There an ,(E)/(Z)-Dilemma'?

    HELVETICA CHIMICA ACTA, Issue 4 2010
    Dieter Seebach
    Abstract The structures of iminium salts formed from diarylprolinol or imidazolidinone derivatives and ,,, -unsaturated aldehydes have been studied by X-ray powder diffraction (Fig.,1), single-crystal X-ray analyses (Table,1), NMR spectroscopy (Tables,2 and 3, Figs.,2,7), and DFT calculations (Helv. Chim. Acta2009, 92, 1, 1225, 2010, 93, 1; Angew. Chem., Int. Ed.2009, 48, 3065). Almost all iminium salts of this type exist in solution as diastereoisomeric mixtures with (E)- and (Z)-configured +NC bond geometries. In this study, (E)/(Z) ratios ranging from 88,:,12 up to 98,:,2 (Tables,2 and 3) and (E)/(Z) interconversions (Figs.,2,7) were observed. Furthermore, the relative rates, at which the (E)- and (Z)-isomers are formed from ammonium salts and ,,, -unsaturated aldehydes, were found to differ from the (E)/(Z) equilibrium ratio in at least two cases (Figs.,4 and 5,,a, and Fig.,6,,a); more (Z)-isomer is formed kinetically than corresponding to its equilibrium fraction. Given that the enantiomeric product ratios observed in reactions mediated by organocatalysts of this type are often ,99,:,1, the (E)-iminium-ion intermediates are proposed to react with nucleophiles faster than the (Z)-isomers (Scheme,5 and Fig.,8). Possible reasons for the higher reactivity of (E)-iminium ions (Figs.,8 and 9) and for the kinetic preference of (Z)-iminium-ion formation are discussed (Scheme,4). The results of related density functional theory (DFT) calculations are also reported (Figs.,10,13 and Table,4). [source]


    The Crow Corvus corone hybrid zone in southern Denmark and northern Germany

    IBIS, Issue 4 2005
    FREDRIK HAAS
    In hybrid zones genetically differentiated populations meet and interbreed. As they result from ongoing divergence and potential speciation, such zones provide opportunities to study how different factors affect this process. One well-known avian hybrid zone is that between the Hooded Crow Corvus corone cornix and Carrion Crow C. c. corone, which extends throughout much of Europe. We compare the current position and width of the zone in southern Denmark and northern Germany with that described in detail by Meise in 1928. A GPS technique was used to determine the geographical position of more than 1000 Crows in established pairs in which all individuals were classified as either Carrion, Hooded or hybrid phenotype. The data show that the Carrion Crow has expanded northwards and that this is most pronounced at the eastern side of the study area. Here the hybrid zone has moved around 19 km. However, the width of the zone seems to have remained stable over time. Possible reasons for why the zone may have moved are discussed. [source]


    The paucity of multimethod research: a review of the information systems literature

    INFORMATION SYSTEMS JOURNAL, Issue 3 2003
    John Mingers
    Abstract. ,It has commonly been argued that the use of different research methods within the information system (IS) discipline and within individual pieces of research will produce richer and more reliable results. This paper reports on a survey of the IS literature to discover the extent of multimethod research. The findings are that such work is relatively scarce, and where it occurs involves only a small set of traditional methods. Possible reasons for this are discussed. [source]


    Dementia Care Mapping reconsidered: exploring the reliability and validity of the observational tool

    INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, Issue 8 2004
    A. Thornton
    Abstract Background Dementia Care Mapping (DCM) is a widely used observational method for evaluating the service quality provided to people with dementia. However, there is little evidence concerning its reliability and validity when used by routine care staff for whom it was designed. Method The study evaluated levels of inter-observer agreement; The ability of the five-minute time frame to reflect the ,actual passing of time'; And the nature of the relationship between individual Well/Ill-Being values (WIB) and dependency levels. Data collected using DCM and continuous time sampling (CTS) were compared. The methods were used in parallel where the CTS coder and the DCM mapper(s) observed the same participants. Observations were carried out with 64 people with dementia within a day hospital and a continuing care ward. Inter-observer agreement was calculated across 20 participants. Dependency levels were measured using the Clifton Assessment Procedure for the Elderly (CAPE) (Pattie and Gilleard, 1979). Results Low levels of inter-observer agreement were found where 11 of the 25 Behaviour Category codes and all six Well/Ill-being Codes produced unacceptable kappas (<0.6). The Behaviour coding frame provided a meaningful picture of activities participants engaged in, but significantly underestimated participant levels of inactivity. A strong relationship was demonstrated between participants' WIB score and levels of dependency, thus DCM was unable to measure well-/ill-being as a separate construct from participants' levels of dependency. Conclusions Questions were raised regarding the reliability and validity of DCM as used by routine care staff. Possible reasons for this, and suggestions for amendments are made. Copyright © 2004 John Wiley & Sons, Ltd. [source]


    Does the method of data collection affect patients' evaluations of quality of care?

    INTERNATIONAL JOURNAL OF NURSING PRACTICE, Issue 6 2000
    Bodil Wilde Larsson RNT
    The aim of the study was to compare two methods of data collection,personal interviews and self-administered questionnaires,with patients' evaluations of the quality of care they received. The sample consisted of 41 matched pairs of inpatients at a medical clinic. In each pair, one patient was interviewed and one responded to a questionnaire. Data were collected using the questionnaire ,Quality from the Patients Perspective' (QPP). The QPP consists of 54 items designed to measure the following four quality dimensions: (i) the medical,technical competence and (ii) the degree of identityorientation in the action of the caregivers; (iii) the physical,technical conditions; and (iv) the sociocultural atmosphere of the care organization. Results showed that patients who were interviewed had significantly less favourable scores on the ,softer' quality dimension scales,the identity-oriented approach of the caregivers and the sociocultural atmosphere of the care setting. Possible reasons for this were discussed, including the possibility that the questions designed to measure these two dimensions were more abstract and emotionally loaded than the items of the other two quality dimensions. [source]


    Discrimination and Well-Being: Perceptions of Refugees in Western Australia

    INTERNATIONAL MIGRATION REVIEW, Issue 1 2008
    Farida Fozdar
    This paper reports the apparent paradox of high levels of discrimination experienced by humanitarian migrants to Australia, in the labor market and everyday life, yet simultaneous reporting of positive well-being. How can people feel discriminated against, yet still be relatively satisfied with life? The study draws on quantitative and qualitative data from a study of 150 refugees from the former Yugoslavia, the Middle East, and Africa. Possible reasons for the level of well-being are explored, including "relative deprivation theory," as well as various resiliency and mitigating factors, including personal and social supports. The notion of eudaimonic well-being , whereby experiences of difficulty produce positive well-being , is also applied to the findings. The negative experiences and perceptions appear to map onto low-level dissatisfaction or disgruntlement, and specifically directed or contained disappointment, rather than serious dissatisfaction with life generally, orientation to Australia, or negative subjective well-being. [source]


    Commercial considerations in tissue engineering

    JOURNAL OF ANATOMY, Issue 4 2006
    Jonathan Mansbridge
    Abstract Tissue engineering is a field with immense promise. Using the example of an early tissue-engineered skin implant, Dermagraft, factors involved in the successful commercial development of devices of this type are explored. Tissue engineering has to strike a balance between tissue culture, which is a resource-intensive activity, and business considerations that are concerned with minimizing cost and maximizing customer convenience. Bioreactor design takes place in a highly regulated environment, so factors to be incorporated into the concept include not only tissue culture considerations but also matters related to asepsis, scaleup, automation and ease of use by the final customer. Dermagraft is an allogeneic tissue. Stasis preservation, in this case cryopreservation, is essential in allogeneic tissue engineering, allowing sterility testing, inventory control and, in the case of Dermagraft, a cellular stress that may be important for hormesis following implantation. Although the use of allogeneic cells provides advantages in manufacturing under suitable conditions, it raises the spectre of immunological rejection. Such rejection has not been experienced with Dermagraft. Possible reasons for this and the vision of further application of allogeneic tissues are important considerations in future tissue-engineered cellular devices. This review illustrates approaches that indicate some of the criteria that may provide a basis for further developments. Marketing is a further requirement for success, which entails understanding of the mechanism of action of the procedure, and is illustrated for Dermagraft. The success of a tissue-engineered product is dependent on many interacting operations, some discussed here, each of which must be performed simultaneously and well. [source]


    On the relation between temporal variability and persistence time in animal populations

    JOURNAL OF ANIMAL ECOLOGY, Issue 6 2003
    Pablo Inchausti
    Summary 1The relationship between temporal variability, spectral redness and population persistence for a large number of long-term time series was investigated. Although both intuition and theory suggest that more variability in population abundance would mean greater probability of extinction, previous empirical support for this view has not been conclusive. Possible reasons are the shortage of long-term data and the difficulties of adequately characterizing temporal variability, two issues that are explicitly addressed in this paper. 2We examined the relationship between population variability and quasi-extinction time (measured as the time required to observe a 90% decline of population abundance) for a large set of data comprising 554 populations for 123 species that were censused for more than 30 years. Two aspects of temporal variability were considered in relation with the quasi-extinction time: a baseline value (coefficient of variation over a fixed, 30-year, time scale), and a measure of the rate of increase of the population variability over time (spectral exponent). 3The results show that the quasi-extinction time was shorter for populations having higher temporal variability and redder dynamics. The relation between persistence time and population variability was compared for different taxa, trophic levels, habitat type (aquatic and terrestrial) and body sizes and compared with theoretical expectations. [source]


    Does Holling's disc equation explain the functional response of a kleptoparasite?

    JOURNAL OF ANIMAL ECOLOGY, Issue 4 2001
    R. W. G. Caldow
    Summary 1Type II functional responses, which can be described by Holling's disc equation, have been found in many studies of predator/prey and host/parasite interactions. However, an increasing number of studies have shown that the assumptions on which the disc equation is based do not necessarily hold. We examine the functional response of kleptoparasitically feeding Arctic skuas (Stercorarius parasiticus L.) to the abundance of fish-carrying auks and, by examination of the assumptions of the disc equation, test whether it can explain the function. 2The rate at which individual skuas make successful chases is a decelerating function of the abundance of auks. However, it would appear that this is not determined by factors that influence their probability of success, but by the rate at which they initiate chases. This too is a decelerating function of the abundance of auks. Arctic skuas have a Type II functional response. 3Although Arctic skuas exhibited a direct numerical response there was no evidence that components of predation connected to the density of predators (direct prey stealing, or increased host avoidance) had any effect on the rate at which individual skuas made chases or were successful in their chases. We conclude that the observed functional response is free from any effects of interference. 4We suggest that abnormally high levels of foraging effort expended by breeding skuas and their poor breeding success in the years of observation argue against the limit to the observed functional response being determined by skuas' energetic requirements. 5Several of the assumptions underlying the disc equation do not hold. The duration of chases (handling time) was not a constant; it decreased with increasing host abundance. Moreover, the chase duration predicted by the disc equation, if handling time limited the functional response, was far in excess of that observed. Furthermore, the observed rate of decline in the searching time per victim with increasing host abundance suggested that skuas' instantaneous rate of discovery was also not constant. Possible reasons for these observations are discussed. The basic disc equation may describe Arctic skuas' functional response, but it cannot explain it. [source]


    Care Standards in Homes for People with Intellectual Disabilities

    JOURNAL OF APPLIED RESEARCH IN INTELLECTUAL DISABILITIES, Issue 3 2008
    Julie Beadle-Brown
    Background, National minimum standards for residential care homes were introduced following the Care Standards Act 2000 in response to concern about the lack of consistency and poor quality services. These standards are intended to reflect outcomes for service users and to be comprehensive in scope. Method, This study compared ratings made by care standards inspectors with research measures for 52 homes for people with intellectual disabilities serving 299 people. The research measures focused on the lived experience of residential care, including engagement in meaningful activity, choice and participation in activities of daily living. They also included measures of related care practices and organizational arrangements. Results, The research measures were in general significantly correlated with each other. Most of the care standards ratings were also correlated with each other. However, only two of 108 correlations between care standards and research measures were significant. Possible reasons for this are discussed. Conclusions, This study confirms that the review of national minimum standards and modernization of inspection methods recently announced by the Department of Health and the Commission for Social Care Inspection are timely and appropriate. [source]


    Update on the Management of Hypertension: Recent Clinical Trials and the JNC 7

    JOURNAL OF CLINICAL HYPERTENSION, Issue 2004
    Marvin Moser MD Editor in Chief
    The following issues are highlighted: Emphasis is placed on the importance of systolic blood pressure elevations in estimating risk and in determining prognosis. A review of placebo-controlled clinical trials indicates that cardiovascular events are statistically significantly reduced with diuretic- or , blocker-based treatment regimens. The question of whether blood pressure lowering alone or specific medications make the difference in outcome is discussed. Based on the results of numerous trials, it is apparent that blood pressure lowering itself is probably of greater importance in reducing cardiovascular events than the specific medication used. Meta-analyses suggest, however, that the use of an agent that blocks the renin-angiotensin aldosterone system is probably more effective in diabetics and in patients with nephropathy than a regimen based on calcium channel blocker therapy. The Antihypertensive and Lipid-Lowering treatment to Prevent Heart Attack Trial (ALLHAT) reported no overall difference in coronary heart disease outcome among patients treated with a diuretic-based compared to a calcium channel blocker- or an angiotensin-converting enzyme inhibitor-based treatment program. However, patients in the diuretic group experienced fewer episodes of heart failure than in the calcium channel blocker group and fewer episodes of heart failure and strokes than those in the angiotensin-converting enzyme inhibitor group. Results were similar in diabetics and nondiabetics. Possible reasons for this outcome are discussed. The Australian National Blood Pressure 2 study, which was unblinded, reported a marginally significantly better outcome only in male patients receiving an angiotensin-converting enzyme inhibitor-based regimen compared to those receiving a diuretic-based program. Finally, the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) is reviewed. Highlights of this report include the new designation of prehypertension, i.e., blood pressures of 120,139 mm Hg/80,89 mm Hg. The JNC 7 suggested that diuretics should be the first-step drug of choice in most patients, but listed numerous specific reasons why other agents should be used in special situations. The report stressed that the majority of patients will require two or more medications to achieve goal blood pressure. [source]


    Prospective Surveillance of Hypertension in Firefighters

    JOURNAL OF CLINICAL HYPERTENSION, Issue 5 2003
    Elpidoforos S. Soteriades MD
    The authors evaluated blood pressure and antihypertensive medication use in 334 firefighters in an occupational medical surveillance program. Firefighters received written summaries of their examination results, including blood pressures, and were encouraged to see their personal physicians for any abnormal results. The mean age of the participants was 39 years, and the vast majority were men (n=330). The prevalence of hypertension was 20% at baseline (1996), 23% in 1998, and 23% in 2000. Among firefighters with high blood pressure readings, only 17%, 25%, and 22% were taking antihypertensive medications at the baseline, 1998, and 2000 examinations, respectively. Medical surveillance was effective in detecting hypertension in firefighters; however, after 4 years of follow-up, only 42% of hypertensives were receiving treatment with medications, including only 22% of firefighters with hypertensive readings. Overall, 74% of hypertensives were not adequately controlled. Possible reasons for low treatment rates may be the inadequate recognition among primary care physicians that mild hypertension is a significant risk factor for cardiovascular disease. [source]


    Is EMDR an exposure therapy?

    JOURNAL OF CLINICAL PSYCHOLOGY, Issue 1 2002
    A review of trauma protocols
    This article presents the well established theoretical base and clinical practice of exposure therapy for trauma. Necessary requirements for positive treatment results and contraindicated procedures are reviewed. EMDR is contrasted with these requirements and procedures. By the definitions and clinical practice of exposure therapy, the classification of EMDR poses some problems. As seen from the exposure therapy paradigm, its lack of physiological habituation and use of spontaneous association should result in negligible or negative effects rather than the well researched positive outcomes. Possible reasons for the effectiveness of EMDR are discussed, ranging from the fundamental nature of trauma reactions to the nonexposure mechanisms utilized in information processing models. © 2002 John Wiley & Sons, Inc. J Clin Psychol 58: 43,59, 2002. [source]


    Physiological effects of dominance hierarchies: laboratory artefacts or natural phenomena?

    JOURNAL OF FISH BIOLOGY, Issue 1 2002
    K. A. Sloman
    Studies of fish behaviour have demonstrated the existence of social interactions that result in dominance hierarchies. In environments in which resources, such as food, shelter and mates, are limited, social competition results in some fish becoming dominant and occupying the most profitable positions. This behaviour has been observed in natural environments and also in many laboratory-based experiments. When two fish have been confined in a small tank, one of them usually has exhibited behaviour that suggests it is dominant over the other submissive animal. Physiological consequences of social interaction can be seen in both dominants and subordinates but are more extreme in the subordinate. However, this scenario is without doubt an artificial situation. Fewer experiments have been conducted using laboratory experiments that are more socially and physically complex than those experienced by dyads in tanks. In simple fluvial tanks, through which water is recirculated, the physiological responses of fish to social competition have generally been qualitatively similar to those recorded among dyads. However, when environmental disturbances, complex resource distributions, increase in water flushing, presence of predators and competing species of fish have been included in experimen-tal designs, there have been fewer, diminished or no physiological dierences between dominant and subordinate fish. There have been very few studies of physiology in relation to dominance in natural habitats, and those that have been conducted suggest that under some circumstances hierarchies may cause less intense physiological responses than have been suggested based on results of laboratory studies in simple environments. Possible reasons for these variations are discussed. The need is identified for a well structured experimental approach to the investi-gation of the causes and consequences of hierarchies if the ecology of wild fish is to be modelled eectively based on physiological processes. It is also suggested that the further development and application of techniques for monitoring physiologies of fish in the wild is important. [source]


    The biology and management of wireworms (Agriotes spp.) on potato with particular reference to the U.K.

    AGRICULTURAL AND FOREST ENTOMOLOGY, Issue 2 2001
    William E. Parker
    Summary 1 This paper reviews and interprets relevant work on the biology and management of wireworms (Agriotes spp.) within the context of potato production in Europe, with particular reference to the U.K. Although the review concentrates on Agriotes spp., the extensive world literature on other Elateridae of economic importance is also drawn upon. 2 Possible reasons for the apparent increase in the importance of wireworms on the potato crop are discussed, followed by a review of wireworm biology, risk assessment techniques (soil sampling, bait trapping and adult pheromone trapping), crop damage, and cultural, biological and chemical control methods. 3 It is clear that the process of site risk assessment followed by appropriate control measures (usually insecticide use) will remain the mainstay of wireworm management programmes. However, there is considerable scope for adopting new risk assessment techniques, such as pheromone trapping of adult beetles. 4 These control measures will need to be underpinned by a greater understanding of wireworm biology, particularly adult dispersal. Factors affecting the initiation and maintenance of wireworm populations in individual fields also require further study. The current use of insecticides could also be optimized by a better appreciation of the interactions between insecticide use, potato variety choice and harvest dates. [source]


    The relationship between levels of mood, interest and pleasure and ,challenging behaviour' in adults with severe and profound intellectual disability

    JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, Issue 3 2002
    E. Ross
    Abstract Background Research on affective disorders in adults with intellectual disability (ID) suggests that depression may not present a ,classic picture' in individuals with severe and profound ID, but may include challenging behaviours, which are referred to as ,atypical symptoms', such as self-injury, aggression and irritability. The aim of the present study was to explore whether there is an association between constructs relating closely to the core symptoms of depression and challenging behaviours in adults with severe and profound ID. Method Mood and levels of interest and pleasure were measured in 53 adults with severe or pro-found ID using the Mood, Interest and Pleasure Questionnaire (MIPQ). Results Two groups of adults were identified based on MIPQ scores: (1) a ,low mood' group (lowest score = 12); and (2) a comparison group (highest scoring = 12). The groups were clearly differentiated on the MIPQ (P < 0.0001), but were comparable on age, gender and medication use. The Challenging Behaviour Interview showed no difference between the two groups in self-injury, aggression or disrupting the environment. A secondary analysis revealed that participants who showed challenging behaviour scored significantly lower on the MIPQ than those who did not show challenging behaviour. Conclusions Possible reasons for these results and considerations for future studies are discussed. [source]


    Oestrogen Receptor ,: Role in Neurohypophyseal Neurones

    JOURNAL OF NEUROENDOCRINOLOGY, Issue 4 2004
    C. D. Sladek
    Abstract The robust expression of oestrogen receptor , (ER-,) in magnocellular vasopressin neurones has focused attention on the role of this receptor and the gonadal steroids in the regulation of vasopressin secretion. Although the effects of gonadal steroids on vasopressin secretion have been the subject of many studies, there is no consensus in the literature as to their role. Possible reasons for the diverse findings are discussed, including diversity in the types, site and level of expression of steroid receptors across species, gender and physiological conditions. The physiological regulation of expression is of particular interest because ER-, mRNA expression in vasopressin neurones is inversely correlated to the osmotic state of the animal. Chronic hyperosmolality inhibits ER-, mRNA expression in magnocellular vasopressin neurones, while chronic hypo-osmolality enhances expression. This is consistent with an inhibitory role for ER-, because hyperosmolality is a potent stimulus for vasopressin secretion, whereas vasopressin secretion is maximally inhibited by chronic hypo-osmolality. An inhibitory role is also indicated by in vitro experiments demonstrating inhibition of osmotically stimulated vasopressin secretion by oestrogen and testosterone, and ER-, mediated inhibition of NMDA-stimulated vasopressin secretion. The challenge remains to elucidate the mechanism of this inhibition, and to understand its significance for maintenance of whole-body fluid and electrolyte homeostasis. [source]


    A Gender Perspective on Conflict Management Strategies of Nurses

    JOURNAL OF NURSING SCHOLARSHIP, Issue 1 2001
    Patricia E.B. Valentine
    Purpose: To apply a gender perspective to synthesis of research findings on conflict management. Organizing Construct: The Thomas-Kilmann Mode Instrument (TKI), for measuring five conflict-handling strategies: avoiding, compromising, collaborating, accommodating, and competing. Method: Nursing research studies with the TKI and other studies are synthesized from perspectives in three gender theories. Conclusions: Findings were that two conflict management strategies, avoiding and compromising, were used predominantly by all categories of nurses. Possible reasons for over- and underuse of the remaining three strategies (collaborating, accommodating, competing) are described. Implications of these findings for nurses and nursing organizations are discussed. [source]


    The Effects of Oligosaccharide and Spores from Aspergillus niger on the Defence Responses of Taxus chinensis Leaves In vitro

    JOURNAL OF PHYTOPATHOLOGY, Issue 10 2003
    M. Y. Li
    Abstract Spores and oligosaccharide of a strain of Aspergillus niger, which had been isolated from the inner bark of Taxus chinensis, were used to treat T. chinensis leaves. The spores decreased the dry weight and chlorophyll content of the leaves, but increased their malondialdehyde content; oligosaccharide induced similar but more moderate changes. The changes in soluble protein, phenolic content, and peroxidase and phenylalanine ammonia-lyase activity were also analysed. Oligosaccharide significantly increased all these, whereas the spores had contrary effects. Results indicate that oligosaccharide, but not the fungal spores, elicited a defence reaction in T. chinensis. Possible reasons for these different effects on T. chinensis leaves in vitro are discussed. [source]


    Synthesis and stability of linear and star polymers containing [C60] fullerene

    JOURNAL OF POLYMER SCIENCE (IN TWO SECTIONS), Issue 14 2001
    Dimitris Pantazis
    Abstract Linear and symmetric star block copolymers of styrene and isoprene containing [C60] fullerene were synthesized by anionic polymerization and appropriate linking postpolymerization chemistry. In all block copolymers, the C60 was connected to the terminal polyisoprene (PI) block. The composition of the copolymers was kept constant (,30% wt PI), whereas the molecular weight of the diblock chains was varied. The polymers were characterized with a number of techniques, including size exclusion chromatography, membrane osmometry, and 1H NMR spectroscopy. The combined characterization results showed that the synthetic procedures followed led to well-defined materials. However, degradation of the fractionated star-shaped copolymers was observed after storage for 2 months at 4 °C, whereas the nonfractionated material was stable. To further elucidate the reasons for this degradation, we prepared and studied a four-arm star copolymer with the polystyrene part connected to C60 and a six-arm star homopolymer of styrene. These polymers as well as linear copolymers end-capped, through N<, with C60 were stable. Possible reasons are discussed. © 2001 John Wiley & Sons, Inc. J Polym Sci Part A: Polym Chem 39: 2494,2507, 2001 [source]


    Glaciomarine deposition around the Irish Sea basin: some problems and solutions

    JOURNAL OF QUATERNARY SCIENCE, Issue 5 2001
    Dr. Jasper Knight
    Abstract Reconstructing the depositional processes and setting (marine or terrestrial depositional environment) of late Devensian age glacigenic sediments around the Irish Sea basin (ISB) is critical for developing an all-embracing and consistent glacial model that can account for all observed field evidence. Identifying episodes of marine and terrestrial glacial deposition from field data is considered the first step in achieving this goal. Criteria for distinguishing marine and terrestrial glacial environments in the ISB include the geomorphology, sedimentology and faunal content (biofacies) of the associated deposits. Exposures of glacigenic sediments around the ISB are very diverse in terms of their morphosedimentary characteristics and associated biofacies, and thus inferred depositional processes and setting. Possible reasons for the diverse geological record include the differing geometry of eastern and western ISB coasts, time-transgressive ice retreat, and differential land rebound effects as a result of forebulge collapse and neotectonics. Poor geochronometric control on ice sheet events has not helped the correlation of ISB events with glacial and climatic events elsewhere. Future investigations of glacial sites around the ISB should use an integrated methodological approach involving a range of geomorphological, sedimentary and biofacies data, and dating control where possible. This will help in developing a more precise and holistic late Devensian glacial model that is constrained rigorously by field geological evidence. Copyright © 2001 John Wiley & Sons, Ltd. [source]


    Letter knowledge precipitates phoneme segmentation, but not phoneme invariance

    JOURNAL OF RESEARCH IN READING, Issue 3 2004
    Julia M. Carroll
    There is a wealth of evidence linking letter knowledge and phoneme awareness, but there is little research examining the nature of this relationship. This article aims to elucidate this relationship by considering the links between letter knowledge and two sub-skills of phoneme awareness: phoneme segmentation and phoneme invariance. Two studies are reported. The first study consisted of an eight-month longitudinal study with 56 pre-literate children. No child within this group was successful on any phoneme awareness task unless they knew at least one letter. Letter knowledge was also a significant predictor of later phoneme completion and deletion. The hypothesis that letter knowledge is an important precursor for phoneme awareness was then investigated in a small-scale intervention study with ten children. These children were taught letters and their phoneme awareness was monitored. It was found that letter knowledge was specifically related to the development of phoneme segmentation in pre-literate children. Possible reasons for this finding are discussed. [source]