Possible Indications (possible + indication)

Distribution by Scientific Domains


Selected Abstracts


Angioplasty and stenting of symptomatic and asymptomatic vertebral artery stenosis: to treat or not to treat

EUROPEAN JOURNAL OF NEUROLOGY, Issue 2 2010
V. Parkhutik
Background and purpose:, Comprehensive indications for treatment of symptomatic vertebral stenosis remain unavailable. Even less is known about endovascular treatment of asymptomatic cases. We treated symptomatic and asymptomatic vertebral ostium stenosis with angioplasty and stenting and investigated the long term outcome. Methods:, Consecutive patients with two different indications were included. Group 1 (G1) had symptomatic >50% stenosis. Group 2 (G2) had asymptomatic >50% stenosis and severe lesions of anterior circulation and were expected to benefit from additional cerebral blood supply. Results:, Twenty nine vertebral origin stenoses in 28 patients (75% men, mean age 64 ± 9 years) were treated. There were 16 G1 and 13 G2 cases. Technical success rate was 100%. Immediate neurological complications rate was 3.4% (one G1 patient with vertebral TIA due to release of emboli). Two further strokes were seen during follow up (32 ± 24 months): vertebrobasilar stroke in a G2 patient with permeable stent in V1 segment, new ipsilateral V3 occlusion and high-risk cardioembolic source, and carotid stroke in a G1 patient who had had ipsilateral carotid stenting. There were no deaths of any cause. Asymptomatic restenosis was observed in one out of 19 patients from both groups who underwent a follow up angiography. Conclusions:, Angioplasty and stenting appears to be technically feasible and safe in asymptomatic and symptomatic vertebral stenosis. More studies are needed in order to clarify its role in primary and secondary prevention of vertebrobasilar stroke. High risk anterior circulation lesions should be taken into account as a possible indication in patients with asymptomatic vertebral stenosis. [source]


Self-burning versus self-cutting: Patterns and implications of self-mutilation; a preliminary study of differences between self-cutting and self-burning in a Japanese juvenile detention center

PSYCHIATRY AND CLINICAL NEUROSCIENCES, Issue 1 2005
TOSHIHIKO MATSUMOTO md
Abstract, The purpose of the present paper was to examine the differences in clinical features between self-cutters and, self-burners,, to, clarify, clinical, implications, of, self-mutilating, behaviors, other than self-cutting. Subjects were 201 delinquent adolescents consecutively entering a Japanese juvenile detention center from February 2003 to March 2003. The subjects were assessed using a self-reporting questionnaire to evaluate self-mutilation, traumatic events, and problematic behaviors. Beck Depression Inventory-2 (BDI-2) and Adolescent Dissociative Experience Scale (A-DES) were also tested. Subjects were classified into four groups according to self-mutilating behaviors: non-self-cutting or -burning (NSCB), self-cutting (SC), self-burning (SB), and self-cutting and self-burning (SCB). The questionnaire answers and scores of the BDI-2 and A-DES were compared between the four groups. Of 201 subjects, 33 (16.4%) had cut their wrists or forearms at least once, and 72 of 201 (35.8%) had burned themselves at least once. The SC and SCB group had traumatic events, problematic behavior, and various types of self-mutilating behavior more frequently than the other two groups. The SCB group reported additional types of self-mutilating behavior more than the SC group. The SCB group also experienced multiple body customizations compared to the SC group, and exhibited higher scores on the BDI-2 and A-DES than the other three groups. The self-burning without self-cutting may have limited clinical implications. However, the self-burning with self-cutting may suggest depression and dissociation, as well as possible indication of self-mutilating behavior. [source]


Nonlinear determinism in river flow: prediction as a possible indicator

EARTH SURFACE PROCESSES AND LANDFORMS, Issue 7 2007
Bellie SivakumarArticle first published online: 6 DEC 200
Abstract Whether or not river flow exhibits nonlinear determinism remains an unresolved question. While studies on the use of nonlinear deterministic methods for modeling and prediction of river flow series are on the rise and the outcomes are encouraging, suspicions and criticisms of such studies continue to exist as well. An important reason for this situation is that the correlation dimension method, used as a nonlinear determinism identification tool in most of those studies, may possess certain limitations when applied to real river flow series, which are always finite and often short and also contaminated with noise (e.g. measurement error). In view of this, the present study addresses the issue of nonlinear determinism in river flow series using prediction as a possible indicator. This is done by (1) reviewing studies that have employed nonlinear deterministic methods (coupling phase-space reconstruction and local approximation techniques) for river flow predictions and (2) identifying nonlinear determinism (or linear stochasticity) based on the level of prediction accuracy in general, and on the prediction accuracy against the phase-space reconstruction parameters in particular (termed as the ,inverse approach'). The results not only provide possible indications to the presence of nonlinear determinism in the river flow series studied, but also support, both qualitatively and quantitatively, the low correlation dimensions reported for such. Therefore, nonlinear deterministic methods are a viable complement to linear stochastic ones for studying river flow dynamics, if sufficient caution is exercised in their applications and in interpreting the outcomes. Copyright © 2006 John Wiley & Sons, Ltd. [source]


Parietal Gray Matter Volume Loss Is Related to Spatial Processing Deficits in Long-Term Abstinent Alcoholic Men

ALCOHOLISM, Issue 10 2009
George Fein
Background:, We previously demonstrated relatively intact cognitive function (with the exception of suggestive evidence for persistent deficits in spatial information processing) in middle-aged long-term abstinent alcoholics (LTAA, abstinent for 6 months or more) compared to age and gender comparable nonalcoholic controls (NAC) (Fein et al., 2006). Methods:, In the current study, we examine cortical gray matter volumes in the same samples to determine whether gray matter volumes in LTAA are consistent with the cognitive results , i.e., exhibiting gray matter volumes comparable to NAC in most brain regions, except for possible indications of persistent shrinkage in the parietal lobe subserving spatial information processing. Results:, We found gray matter shrinkage in LTAA in the parietal lobe consistent with the spatial processing deficits in this same sample. More compelling, in LTAA, the magnitude of parietal gray matter shrinkage was negatively associated with spatial processing domain performance and positively associated with alcohol dose. Gray matter volume deficits were present in the occipital and other cortical tissue, but poorer visuospatial test performance correlated significantly with smaller volumes in the parietal cortex only. Conclusions:, Taken together, the cognitive and structural imaging data provide compelling evidence that chronic alcohol abuse results in shrinkage of the parietal cortex with associated deficits in spatial information processing. [source]


Intergenerational class mobility in contemporary Britain: political concerns and empirical findings1

THE BRITISH JOURNAL OF SOCIOLOGY, Issue 4 2007
John H. Goldthorpe
Abstract In Britain in recent years social mobility has become a topic of central political concern, primarily as a result of the effort made by New Labour to make equality of opportunity rather than equality of condition a focus of policy. Questions of the level, pattern and trend of mobility thus bear directly on the relevance of New Labour's policy analysis, and in turn are likely be crucial to the evaluation of its performance in government. However, politically motivated discussion of social mobility often reveals an inadequate grasp of both empirical and analytical issues. We provide new evidence relevant to the assessment of social mobility , in particular, intergenerational class mobility , in contemporary Britain through cross-cohort analyses based on the NCDS and BCS datasets which we can relate to earlier cross-sectional analyses based on the GHS. We find that, contrary to what seems now widely supposed, there is no evidence that absolute mobility rates are falling; but, for men, the balance of upward and downward movement is becoming less favourable. This is overwhelmingly the result of class structural change. Relative mobility rates, for both men and women, remain essentially constant, although there are possible indications of a declining propensity for long-range mobility. We conclude that under present day structural conditions there can be no return to the generally rising rates of upward mobility that characterized the middle decades of the twentieth century , unless this is achieved through changing relative rates in the direction of greater equality or, that is, of greater fluidity. But this would then produce rising rates of downward mobility to exactly the same extent , an outcome apparently unappreciated by, and unlikely to be congenial to, politicians preoccupied with winning the electoral ,middle ground'. [source]


Prevalence and associations of partner abuse in women attending general practice: a cross-sectional survey

AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH, Issue 5 2002
Kelsey L. Hegarty
Objective: To deter mine the prevalence and socio-demographic associations of physical, emotional and sexual abuse by a partner or ex-partner for women attending Australian general practices. Method: In 1996, women attending 20 randomly chosen Brisbane inner south region general practices were screened for a history of partner abuse using a self-report questionnaire. Multivariate analyses were conducted on the data, using presence of abuse or not adjusting for cluster effect to obtain prevalence rate ratios for socio-demographic background data and history of violence in the family of origin. Results: Thirty-seven per cent (CI 31.0,42.4) of the survey participants (n=1,836, response rate 78.5%) admitted to having ever experienced abuse in an adult intimate relationship. One in four women (23.3%) had ever experienced physical abuse, one in three (33.9%) emotional abuse and one in 10 (10.6%) sexual abuse. Abused women were 64.1 (CI 44.4,94.1) times more likely to have ever been afraid of any partner than non-abused women. Of women in current relationships (n=1,344), 8.0% self-reported physical or emotional or sexual abuse in the past 12 months and 1.5% all three types of abuse. Associations of abuse included being younger (<60 years), separated or divorced, having a history of child abuse or domestic violence between their parents. Conclusion: Partner abuse is very common in women attending general practices and clinicians need to be alert to possible indications of partner abuse (age, marital status, past history of abuse). [source]