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Portal System (portal + system)
Selected AbstractsEvaluation of the participant-support method for information acquisition in the "Multiplex Risk Communicator"ELECTRONICS & COMMUNICATIONS IN JAPAN, Issue 9 2009Tomohiro Watanabe Abstract In this paper, we propose a smooth risk communication support method for the Multiplex Risk Communicator. There has been a diversification of the social risks to the information-based society, leading to complex social issues, and risk communication is necessary in order to solve the complicated social problems that arise concerning stakeholders with various levels of knowledge and differing standards regarding risks. We introduce a portal system that assists participants to achieve an optimal combination of countermeasures. The characteristics of the proposed method are: first, to classify the stage when participants acquire information; second, to enable smooth transitions during the information acquisition stage; and third, to support information acquisition by offering information portals. © 2009 Wiley Periodicals, Inc. Electron Comm Jpn, 92(9): 24,35, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecj.10092 [source] Neuroendocrine mechanisms controlling female puberty: new approaches, new conceptsINTERNATIONAL JOURNAL OF ANDROLOGY, Issue 1 2006Sergio R. Ojeda Summary Sexual development and mature reproductive function are controlled by a handful of neurones that, located in the basal forebrain, produce the decapeptide luteinizing hormone releasing hormone (LHRH). LHRH is released into the portal system that connects the hypothalamus to the pituitary gland and act on the latter to stimulate the synthesis and release of gonadotrophin hormones. The pubertal activation of LHRH release requires coordinated changes in excitatory and inhibitory inputs to LHRH-secreting neurones. These inputs are provided by both transsynaptic and glia-to-neurone communication pathways. Using cellular and molecular approaches, in combination with transgenic animal models and high-throughput procedures for gene discovery, we are gaining new insight into the basic mechanisms underlying this dual control of LHRH secretion and, hence, the initiation of mammalian puberty. Our results suggest that the initiation of puberty requires reciprocal neurone-glia communication involving excitatory amino acids and growth factors, and the coordinated actions of a group of transcriptional regulators that appear to represent a higher level of control governing the pubertal process. [source] Intrahepatic arterioportal fistula: Demonstration by dynamic 3D magnetic resonance angiography in under four secondsJOURNAL OF MAGNETIC RESONANCE IMAGING, Issue 1 2002N. Cem Balci MD Abstract We report a case of a 35-year-old patient with clinical symptoms of portal hypertension that underwent dynamic contrast-enhanced 3D magnetic resonance angiography (MRA) of the abdomen. On breath-hold dynamic contrast-enhanced MRA in less than 4 seconds, contrast passage from the arterial to the portal system was successfully demonstrated. Patient was managed according to MRA findings. J. Magn. Reson. Imaging 2002;16:94,96. © 2002 Wiley-Liss, Inc. [source] Presumed hypoplastic intrahepatic portal system due to patent ductus venosus: Importance of direct occlusion test of ductus venosus under open laparotomyPEDIATRICS INTERNATIONAL, Issue 4 2004Yuka Takehara No abstract is available for this article. [source] The tegument surface membranes of the human blood parasite Schistosoma mansoni: A proteomic analysis after differential extractionPROTEINS: STRUCTURE, FUNCTION AND BIOINFORMATICS, Issue 5 2006Simon Braschi Abstract The blood fluke Schistosoma mansoni can live for years in the hepatic portal system of its human host and so must possess very effective mechanisms of immune evasion. The key to understanding how these operate lies in defining the molecular organisation of the exposed parasite surface. The adult worm is covered by a syncytial tegument, bounded externally by a plasma membrane and overlain by a laminate secretion, the membranocalyx. In order to determine the protein composition of this surface, the membranes were detached using a freeze/thaw technique and enriched by sucrose density gradient centrifugation. The resulting preparation was sequentially extracted with three reagents of increasing solubilising power. The extracts were separated by 2-DE and their protein constituents were identified by MS/MS, yielding predominantly cytosolic, cytoskeletal and membrane-associated proteins, respectively. After extraction, the final pellet containing membrane-spanning proteins was processed by liquid chromatographic techniques before MS. Transporters for sugars, amino acids, ions and other solutes were found together with membrane enzymes and proteins concerned with membrane structure. The proteins identified were categorised by their function and putative location on the basis of their homology with annotated proteins in other organisms. [source] Vascular Development and Differentiation During Human Liver OrganogenesisTHE ANATOMICAL RECORD : ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, Issue 6 2008Sophie Collardeau-Frachon Abstract The vascular architecture of the human liver is established at the end of a complex embryological history. The hepatic primordium emerges at the 4th week and is in contact with two major venous systems of the fetal circulation: the vitelline veins and the umbilical veins. The fetal architecture of the afferent venous circulation of the liver is acquired between the 4th and the 6th week. At the end of this process, the portal vein is formed from several distinct segments of the vitelline veins; the portal sinus, deriving from the subhepatic intervitelline anastomosis, connects the umbilical vein, which is the predominant vessel of the fetal liver, to the portal system; the ductus venosus connects the portal sinus to the vena cava inferior. At birth, the umbilical vein and the ductus venosus collapse; the portal vein becomes the only afferent vein of the liver. The efferent venous vessels of the liver derive from the vitelline veins and are formed between the 4th and the 6th week. The hepatic artery forms at the 8th week; intrahepatic arterial branches progressively extend from the central to the peripheral areas of the liver between the 10th and the 15th week. Hepatic sinusoids appear very early, as soon as hepatic cords invade the septum transversum at the 4th week. They then progressively acquire their distinctive structural and functional characters, through a multistage process. Vascular development and differentiation during liver organogenesis is, therefore, a unique process; many of the cellular and molecular mechanisms involved remain poorly understood. Anat Rec, 291:614,627, 2008. © 2008 Wiley-Liss, Inc. [source] Successful Urgent Transplantation of an Adult Kidney into a Child with Inferior Vena Cava ThrombosisAMERICAN JOURNAL OF TRANSPLANTATION, Issue 8 2009R. B. Stevens Poor venous drainage options following inferior vena cava (IVC) thrombosis have been considered to complicate or preclude renal transplantation of adult kidneys into pediatric patients. We describe urgent renal transplantation in a 5-year-old (15.3 kg) male with IVC thrombosis using an adult living donor. Preoperative magnetic resonance venography revealed a patent infrahepatic/suprarenal vena cava and portal system. In surgery, the right liver lobe was mobilized sufficiently to anastomose the graft renal vein to the native IVC at the confluence of the native left renal vein and proximal vena cava. Graft function has remained excellent with serum creatinine of 0.5 mg/dL at 36 months. IVC thrombosis need not preclude successful transplantation of adult-sized kidneys into children. [source] Expression of Agouti-related Protein (Agrp) and its mRNA in the Hypothalamus and the Adrenal Gland of the Duck (Anas platyrhynchos)ANATOMIA, HISTOLOGIA, EMBRYOLOGIA, Issue 2005N. Mirabella Introduction:, Agouti-related protein (AGRP) is a neuropeptide involved in the control of body weight. Morphological and pharmacological studies have shown that AGRP is implicated in the central control of feeding behaviour acting as an endogenous antagonist of the alpha-melanocyte stimulating hormone (,-MSH), a potent satiety-inducing factor, at the melanocortin 3 (MC3)- and four (MC4)-receptors. Aim:, The aim of the present study was to investigate the expression of AGRP and its mRNA in the hypothalamus and adrenal gland of the duck and, in particular, to establish which type of adrenal tissue is involved in the AGRP synthesis. Methods:, Immunohistochemistry, western blotting, reverse transcriptase (RT)-polimerase chain reaction (PCR). Results and Discussion:, AGRP-immunoreactivity was observed in neurons and nerve fibres in a restricted area of the hypothalamus. AGRP-ir neurons were located in the nucleus infundibularis and distributed ventromedially to the third ventricle in the hypothalamic tuberal region. These neurons were round or, with a lesser extent, elongated in shape. AGRP-ir fibres were seen to project to the median eminence (ME) and anterior periventricular hypothalamus. The AGRP ir-fibres in the ME were distributed in the external layer in close vicinity to the capillaries of the hypothalamo-hypophysial portal system. In the avian adrenal gland, AGRP immunoreactivity was observed in the medullary tissue. A partial sequence of AGRP cDNA was identified using RT-PCR cloning and sequencing. This sequence was highly homologous to the corresponding fragment of the chicken AGRP gene. The western blotting analysis of adrenal gland and hypothalamus tissue extracts showed a well-defined single band with an electrophoretic mobility consistent with the molecular weight of the avian AGRP protein. These results demonstrate that AGRP is expressed in the hypothalamus and adrenal glands of the duck and suggest an involvement of this peptide in the regulation of the melanocortin system in birds. [source] | |||||||||||||