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Peripheral Lesions (peripheral + lesion)

Distribution by Scientific Domains
Medical Sciences100%

Selected Abstracts

Reprogramming the Cerebral Cortex: Plasticity Following Central and Peripheral Lesions

EUROPEAN JOURNAL OF NEUROLOGY, Issue 10 2007
K. A. Jellinger
No abstract is available for this article. [source]

Cell type accuracy of transthoracic fine needle aspiration material in primary lung cancer

RESPIROLOGY, Issue 2 2001
Adnan Yilmaz
Objective: The aim of this study was to evaluate the diagnostic accuracy of transthoracic fine needle aspiration (TFNA) materials in establishing the specific cell type in primary lung cancer, and to study the influence of several factors on this accuracy. Methodology: The present study included 129 patients [(12 females, 117 males; mean age 54.6 years (range 25,75)] who underwent thoracotomy. The initial diagnosis was obtained by means of TFNA biopsy in all patients. Transthoracic fine needle aspiration was performed by 22-gauge Chiba needle with fluoroscopy guide in 93 patients and with computed tomography guide in 36 cases. Results: The overall concordance was 73.6% (Kappa = 0.52). The worst agreement was obtained for the large cell carcinoma (40%; Kappa = 0.48). The likelihood of a correct diagnosis using the TFNA specimens was 6.2-fold higher for well-differentiated tumours than for poorly differentiated tumours (P < 0.005). The stage of tumour and diameter of the lesion had no effect on cell agreement. Cell agreement was higher in central lesions than peripheral lesions, but the difference was not statistically significant (P = 0.097). This difference was more significant between patients with central and peripheral epidermoid carcinoma (P = 0.057). Conclusion: In our opinion, cell typing by TFNA may lead to incorrect results in the presence of poor differentiation, mixed tumours and peripheral epidermoid carcinomas. [source]

Teledermatology: Influence of zoning and education on a clinician's ability to observe peripheral lesions

AUSTRALASIAN JOURNAL OF DERMATOLOGY, Issue 3 2002
Keng Chen
SUMMARY Teledermatology can benefit rural and remote communities, where specialist dermatological services may not be readily available. Regarding store-and- forward teledermatology, we hypothesized that the site of a lesion in an image (zoning) may influence a clinician's ability to observe target lesions, and that education on image viewing may improve use of this technology. We examined this by conducting both pre- and post-education studies. The education on image viewing consisted of a presentation on the outcome of the first study-survey on image viewing. The first study demonstrated that zoning influences a clinician's visual attention and that significant, concurrent lesions in the periphery may be missed. The second study demonstrated that brief education could produce a measurable change in observing peripheral lesions. These findings have medico-legal implications and suggest that further education in the use of such technology is necessary in order to optimize patient care and prevent potential errors. [source]

Scanning beyond the limits of standard OCT: OCT scans of the peripheral retina and the anterior chamber angle with a slitlamp integtrated FD-OCT system

ACTA OPHTHALMOLOGICA, Issue 2009
M STEHOUWER
Purpose Exploring the quality of OCT images of the peripheral retina and anterior chamber angle made through a 3-mirror contactlens and a new FD-OCT device integrated into a slit lamp. Methods Patients with peripheral lesions (n=10) and glaucoma (n=10), seen in the outpatient clinic of the Academic Medical Center, were scanned with a Fourier Domain OCT integrated into a common Topcon slitlamp (SLD light source, central wavelength 830 nm, bandwidth 30 nm, 1024 pixel CCD camera, scan speed 5k A-scans per second, up to 1024 A-scans per b-scan). For posterior segment scans a fast Z-tracking system in the reference arm compensates for the dynamic character (movements of patient, handheld lens, slitlamp) of the examination. Scans of peripheral lesions, and the anterior chamber angle were made with a 3-mirror lens, while simultaneously the lesions were observed with the slitlamp. Results Scans of the peripheral retina obtained with a 3-mirror lens with the FD-OCT integrated into the slitlamp were of reasonably good quality and lesions, like peripheral laser scars, could be clearly identified. Compared to stand alone OCT systems, the integrated OCT system reached more peripheral lesions. The anterior chamber angle scanned through a 3-mirror lens enabled scans of the angle structures. Conclusion It is possible to scan the peripheral retina and anterior chamber angle through a 3-mirror contact lens with the slitlamp with integrated OCT. These scans could be of clinical interest in patients with pathology in the peripheral retina pathology or the anterior chamber angle. [source]